69 results about "Atropine sulfate" patented technology

The invention discloses an instant atropine sulphate eye gel and a preparation method thereof. According to the invention, 1000ml of the instant atropine sulphate eye gel contains 1g to 20g of atropine sulphate, 0.05g to 1g of preservative, 1.0g to 7.5g of osmotic pressure adjusting agent, and 30g to 150g of gel stroma, and the rest includes acid-alkali buffer and water for injection. The invention, through the optimization of accessories and the improvement of the technique, enriches the pharmaceutical dosage form of the atropine sulphate, greatly prolongs the time for which the medicine stays in the eyes, and not only improves the curative effect and shortens the time for reaching the function peak, but also reduces the amount of the medicine flowing into and absorbed by dacryocysts and relieves the side effect and toxic reaction of the atropine sulphate.

The disclosure provides a pharmaceutical composition for treating social anxiety, performance anxiety, and social phobia comprising a therapeutic amount for die treatment of a patient of a β-adrenergic receptor antagonist, an anti-diarrheal compound, and an optional anticholinergic compound. The β-adrenergic receptor antagonist may be the lipophilic β-blocker propranolol HCl, the anti-diarrheal compound may be the opioid diphenoxylate HCl, and the optional anticholinergic compound may be atropine sulfate. The composition for treating performance anxiety and social phobia can further include a pharmaceutically acceptable carrier. A method of preventing or treating social anxiety, performance anxiety, and social phobia in a patient is also provided, comprising administering a composition of the disclosure to a patient in need of such treatment. The composition administered in the present method comprises a therapeutic amount of a β-adrenergic receptor antagonist, an anti-diarrheal compound, and an optional anticholinergic compound.

The invention relates to the technical field of pharmaceutical preparations, and particularly discloses an eye drop for treating myopia and a preparation method thereof. The eye drop comprises atropine sulfate, a thickening agent, a pH regulator, an osmotic pressure regulator and a metal ion chelating agent, wherein the solvent is water, the content of atropine sulfate is 0.001-0.1 wt%. The eye drop for treating myopia is a low-concentration atropine sulfate eye drop, and the metal ion chelating agent is selectively added. Moreover, the eye drop is supplemented with auxiliary materials for improving the stability of atropine sulfate, such as the pH regulator, the osmotic pressure regulator and the thickening agent, so that the stability of the low-concentration atropine sulfate solution isobviously improved, the safety is good, the occurrence of myopia of teenagers can be effectively prevented and delayed, the irritation to eye tissue cells is small, and the eye drop is particularly suitable for teenagers with myopia below 400 degrees.

The invention relates to the drug quality detection field, in particular to a method for detecting the quality of a blood-activating analgesic plaster, which comprises the following steps: angelica sinensis, hesperidin, atropine sulfate, chrysophanol and cortex periplocae in the blood-activating analgesic plaster are identified by a thin layer chromatography, and then component contents in the blood-activating analgesic plaster are detected by a gas chromatograph. The method for detecting the quality of the blood-activating analgesic plaster combines the thin layer chromatography and the gas chromatograph for detecting the effective components and contents of the blood-activating analgesic plaster, the detected result is accurate and reliable, the quality of the blood-activating analgesicplaster can be effectively monitored, and the method is simple and convenient and is easy to operate.

The invention discloses a compound solution of diclazuril for curing avian coccidium infection and a preparation method thereof, aiming to provide a solution for curing avian coccidium infection, reducing the drug resistance of avian coccidium and increasing the curative effect and a preparation method thereof. The 100L of solution comprises the following components: 0.1-2kg of diclazuril, 3-15kgof sulfachloropyrazine sodium, 0.05-0.5kg of atropine sulfate, 40L of dimethyl acetamide, 30L of 95% ethanol, 5L of ethanolamine and the balance propylene glycol. In the invention, diclazuril and sulfachloropyrazine sodium are used as components for anti-coccidium and the invention has double function so as to effectively reduce drug resistance rate of coccidium and increase the sensitivity of coccidium; atropine sulfate can effectively reduce the glandular secretion of intestinal tract, dry contents in intestinal tract and avoid poultry from severe dehydration owning to the diarrhea caused bycoccidium infection and from a series of consequent side effects. The product can be mixed with water by arbitrary proportion so that the use of the product is convenient.

The invention relates to veterinary compound apramycin sulfate soluble powder and application thereof. The veterinary compound apramycin sulfate soluble powder is characterized by being prepared by mixing the following components according to unit weight of 100g: 3-25g of apramycin sulfate, 5-10g of colistin sulfate, 0.1-0.2g of atropine sulfate, 2-5mg of epidermal growth factor, and the balance of medically applicable auxiliary materials. The components with optimal contents are as follows: 15g of apramycin sulfate, 5g of colistin sulfate, 0.15g of atropine sulfate, 3mg of epidermal growth factor, and the balance of medically applicable auxiliary materials, wherein the auxiliary materials comprise more than one of sucrose, anhydrous glucose and oral glucose. The invention also discloses the application of the veterinary compound apramycin sulfate soluble powder to treatment of piglet yellow-white scour. By adopting the compound preparation of antibiotics, anticholinergics and epidermal growth factors, the invention has effective treatment effect for piglet yellow-white scour, has the efficacy of treating both the symptoms and root cause and reduces the bacterial resistance probability with simple preparation, obvious effect and wide application.

The invention discloses a veterinary compound norfloxacin nicotinate injection and a preparation method thereof, which aims at providing the veterinary compound norfloxacin nicotinate injection that has rapid onset of action for the treatment for white diarrhea of piglets and can prevent the infection and the secondary infection and treat both manifestation and root cause of disease, and the preparation method that has simple technology and easy realization. In the veterinary compound norfloxacin nicotinate injection, each 100l injection is prepared by the following components: 1 to 8kg of the norfloxacin nicotinate, 2 to 10kg of lincomycin hydrochloride, 0.05 to 0.5kg of atropine sulfate, 0.2kg of sodium sulfite, 0.01kg of EDTA-2Na and the rest of water for injection. By adopting a compound preparation which combines anti-bacterial drugs and antibiotics for usage, and the combining usage of the norfloxacin nicotinate, the lincomycin hydrochloride and the atropine sulfate, the injection of the invention has rapid onset of action for white diarrhea of piglets, effectivity and high efficiency and can ease the stress reactions of the affected animals, significantly ease the clinical symptoms caused by the white diarrhea of piglets, treat both manifestation and root cause of disease, prevent the secondary infection and increase the weight of the pigs.

The invention relates to the field of veterinary drug formulations, and in particular relates to a compound formulation for treating bacterial infection of the digestive tract of livestock and poultry. The compound formulation comprises the following components in every 100ml: 2-10g of ciprofloxacin on ciprofloxacin basis, 1-9g of colistin sulfate on synthesized pure medicine, and 0.03-0.1g of atropine sulfate. The compound formulation is prepared by adopting ciprofloxacin and colistin sulfate with high bacteria sensitivity and strong synergetic bacteria resistance and combining symptomatic treatment medicines by a method for treating both symptom and root cause, so that a remarkable synergetic sterilization effect can be achieved, the drug dosage can be reduced, the cure rate can be improved, the treatment cost can be reduced, and the compound formulation is stable; occurrence of drug resistance of pathogenic bacteria of the digestive tract of livestock and poultry can be effectively avoided; the compound formulation is low in prescription price and convenient to popularize and apply.

The invention discloses compound mequindox injection, and belongs to medicine preparation containing organic components, or anti-infective medicament for livestock. The injection of each 1, 000 liters is prepared by the following raw materials: 100 to 400 kilograms of sodium salicylate, 10 to 150 kilograms of mequindox, 5 to 110 kilograms of gentamicin sulphate, 1 to 20 kilograms of atropine sulfate, 1 to 20 kilograms of chlorphenamine maleate, and the balance being water for injection. The injection adopts combined compound preparation of the mequindox and the gentamicin sulphate, has efficiency and high efficiency for pig bacterial diarrhea, treats both symptoms and root causes, and relieves stress reaction of sick livestock body.

The invention discloses a preparation method for atropine sulfate. The preparation method comprises the following steps: 1) adding dry powder of daturae flower into hydrochloric acid with a concentration of 1 to 4% and a volume 0.5 to 1 time of the volume of the dry powder for wetting and swelling, then adding the swollen daturae flower powder into a percolating barrel, adding the hydrochloric acid with a concentration of 1 to 4%, dipping the powder for 24 h or above and carrying out percolating so as to obtain brown-yellow stiff paste; 2) dissolving brown-yellow stiff paste in acetone, adding active carbon, carrying out decoloring and filtering, adding acid drop by drop until a pH value is less than 7 and carrying out standing at room temperature so as to obtain hyoscyamine sulfate; and 3) spreading hyoscyamine sulfate on a sample disc, putting the sample disc into a baking oven, carrying out heating for racemization, then carrying out cooling to obtain a crude atropine sulfate product, adding ethanol, carrying out dissolving under stirring and then filtering, subjecting a filtrate to crystallization overnight and then successively carrying out pressure-reduced filtering and vacuum drying so as to obtain atropine sulfate. According to the invention, the daturae flower is used as a raw material; acid water is used for percolation and extraction; total alkali is obtained through chloroform extraction; sulfuric acid is added into an acetone solution for salt forming so as to obtain hyoscyamine sulfate, then heating is carried out for racemization, and ethanol recrystallization is carried out to obtain atropine sulfate; and the method is simple in process operation, small in pollution, low in cost and suitable for industrial production.

The invention discloses an injection for treating the paratyphoid of dogs and a preparation method thereof, which aim to provide an injection which has quick effect and can reduce the drug resistant probability of pathogenic bacteria, treat both symptoms and root causes and quicken the recovery, and a preparation method which has simple process and is easy to realize. Per 100L of the injection comprises 2-15kg of sulfamonomethoxine sodium, 1-10kg of lincomycin hydrochloride, 0.05-0.3kg of atropine sulfate, 0.06kg of dexamethasone sodium phosphate, 0.2kg of sodium bisulfite, 0.01kg of EDTA-2Na and the balance of water. The injection adopts antibacterial drugs, antibiotics, glucocorticoids for diminishing inflammation and detoxifying and atropine sulfate for controlling the diarrhea of the dogs and reducing dehydration, and a compound preparation prepared by reasonably proportioning the dosages of the components has the function of double anti-bacteria, can reduce the drug resistant probability of salmonella typhimuria, control the infection of other gram negative bacteria and positive bacteria and accelerate the recovery and has high cure rate.

The present invention provides a compound poplar flower oral liquor. Each 100 ml solution contains medicinal ingredient as follows: ofloxacin 4.0-7.0 g, atropine sulfate 0.03-0.05 g, poplar flower extract liquid 93-96 ml, each 1 ml poplar flowers extract liquid equals to 1.10-1.15 g of poplar flowers raw ingredient. The compound poplar flower oral liquid can prevent and treat diarrhea or intestinal inflammation of the animal efficiently, optimize treating effect. The compound poplar flower oral liquid is added into drinking water for animal in general, each 100 oral liquid is added with 200 jin water, and the patient animal can be cured after taking the oral liquid 2-3 days. The compound poplar flower oral liquid has obvious treating effect and does not relapse after taking.

The invention discloses compound colistin sulfate soluble powder for treating lamb dysentery and a preparation method thereof and aims to provide the compound colistin sulfate soluble powder which hasa quick therapeutic effect on lamb dysentery, has efficacy in secondary infection bacteria and is convenient to use, and the preparation method which has a simple process and is easy to implement. The powder comprises the following components in percentage by weight: 2 to 10 percent of colistin sulfate, 5 to 20 percent of sulfathiazole sodium, 0.05 to 0.5 percent of atropine sulfate, 0.2 percentof vitamin K, and the balance of anhydrous dextrose. The soluble powder is a compound preparation of the combination of four medicaments, wherein the colistin sulfate and the sulfathiazole sodium areantibacterial for killing pathogens, the atropine sulfate controls diarrhea, reduces water loss and accelerates the treatment speed, and the vitamin K prevents and treats intestinal tract bleeding; and the four medicaments are mixed together reasonably so that the powder has a quick response, treats both symptoms and root causes, and can reduce the losses of raisers. The compound colistin sulfatesoluble powder is soluble powder, is soluble in milk, is used for feeding lambs through the milk and is more convenient to use.

The invention discloses an establishing method of a cataract model for live dogs. The method comprises the following steps of selecting a healthy live dog, performing pupil dilating with atropine sulfate on the day before model making, performing pupil dilating once again with the atropine sulfate before model making, performing general anaesthesia on the live dog before model making, then performing needle insertion along the edge of corneosclera, penetrating anterior lens capsules through the pupil, injecting 0.12-0.18mL of 3% hydrogen peroxide into crystalline lenses in multiple points, andafter 10 days, successfully constructing the cataract model for the live dog. According to the method disclosed by the invention, an H2O2 solution having specific dosage and concentration is injectedinto the crystalline lenses of the live dog, and the cataract model is successfully established in the live dog. The method is simple, high in success rate, high in stability and good in repeatability; and medicines adopted by the method are convenient in source, low in price and free form toxins, and an ideal cataract model of an animal live body is provided for development of clinical ophthalmology department of pets.

The invention relates to the field of medicines and provides a composite injection for treating or preventing anesthesia hypotension. 1000 mL of the composite injection comprises 0.1-2g of atropine sulfate, 2-5g of methoxamine hydrochloride, 10-15g of medicinal auxiliary materials and the balance of injection water, and the pH value of the composite injection is adjusted to 4.5+/-0.3. According tothe composite injection provided by the invention, the atropine sulfate and the methoxamine hydrochloride are adopted as active components, the methoxamine hydrochloride and the atropine sulfate arecompounded, and by virtue of the property that an alpha1-adrenergic receptor stimulant can be antagonized by atropine, reflective decreased heart rates caused by methoxamine hydrochloride can be antagonized. After the two components are compounded, a blood pressure boosting effect which is not inferior to that of independently used methoxamine hydrochloride can be achieved, the probability of reflective decreased heart rates can be reduced, and thus the composite injection provided by the invention is relatively safe and effective when being used for treating or preventing anesthesia hypotension.

The invention discloses a compound Ofloxacin solution and a preparation method thereof, aiming at providing a solution with the advantages of treating digestive tract infections and respiratory tract infections of birds with rapid effect, treating both principal and secondary aspects of diseases and reducing drug-applied times and a preparation method thereof. The solution can be injected or orally taken and proper treating methods and administration approaches can be adopted according to disease states and the specific conditions of culturists. Every 100L of solutions comprises 1-10 kg of Ofloxacin, 3-15 kg of lincomycin hydrochloride, 0.05-0.5 kg of atropine sulfates, 0.2-2 kg of doxofylline, 0.01 kg of EDTA (Ethylene Diamine Tetraacetic Acid)-2Na, 10 kg of dimethylacetylamide and 0.5 L of hydrochloric acid. Because the Ofloxacin and the lincomycin hydrochloride are adopted as antibacterial components, the compound Ofloxacin solution can effectively solve the problems of bacterial drug resistance and takes effect on common bacteria causing the digestive tract infections and the respiratory tract infections; and meanwhile, the doxofylline can effectively relieve cough and asthma and inhibit respiratory symptoms, and the atropine sulfates have the rapid effects of inhibiting glandular secretion and reducing the liquid contents of digestive tracts and the respiratory tracts.

An exterior-applied medicine for treating hircus is prepared from atropine sulfate (0.2-0.5 wt.%), sulfate (0.05-0.15) and distilled water (rest). Its advantages are high curative effect, no allergic reaction, and no toxic by-effect.

The invention relates to a compound maquindox injection for veterinary use and a preparation method thereof. The injection is made from maquindox, atropine sulfate, organic solvent and water. As a special compound preparation for veterinary use, the injection has special efficacy on severe diseases caused by treponema such as swine dysentery, piglet yellow dysentery, white dysentery, calf diarrhea, paratyphoid, bacterial enteritis, and the like, and has the advantages of convenient use, short treatment course, low drug resistance, and the like.

The invention provides a compound enteritis capsule. It is characterized by simple treatment, convenient usage and functions of treating bacillary dysentery, acute and chronic enteritis. It makes use of the anti-biotic effect for bacillus coli and Bacillus dysenteriae of furazolidone, acts on intestine smooth muscle by using chlorhydric acid diphenoxylate, gets rid of crawl reflection of partial mucosa to reduce crawl by inhibiting intestine mucosa receptor, and increases intestine wall stage contraction and promotes water back-absorption in the intestine. The atropine sulfate can relieve intestine smooth muscle spasm and inhibit glandular secretion. The capsule comprises five chemical medicine, it can shorten the treating period for bacillary dysentery and acute enteritis, increase cure rate for various chronic colitis, and reduce pain for patient during injection, intravenous drip, bowel lavage and taking traditional medicine.

The invention discloses an oral liquid for treating white scour of chicken and a preparation method thereof, aiming at providing an oral liquid which can be used for treating white scour infection of chicken with treatment of both principal and secondary aspects of disease and is convenient for medicate and a preparation method thereof which has a simple process and is easy to realize. The composition of each 100L of oral liquid is as follow: 1-7kg of enrofloxacin, 5-15kg of sulfamonomethoxine, 1-3kg of TMP (Trimethoprim), 0.1-0.5kg of atropine sulfate, 30L of dimethylformamide, 20L of 95% ethanol, 1-2kg of sodium hydroxide and the balance of water. In the oral liquid disclosed by the invention, all ingredients are combined and reasonably proportioned to play a multiaspect role on the white scour of chicken with treatment of both principal and secondary aspects of disease; in addition, the oral liquid is a compound preparation and can reach the effect of a plurality of medicines through once administration; and the oral liquid is convenient to use and can ease clinical symptoms when chicken are sicken. The oral liquid disclosed by the invention can intersoluble with water according to any proportion and can be medicated in mass group.

The invention discloses a composition for treating chicken necrotizing enterocolitis and a preparation method thereof and aims to provide a composition for treating chicken necrotizing enterocolitis infection with rapid desired effect, bacterium drug-resistant reduction and both principal and secondary treatment of diseases and a preparation method thereof. The composition for treating chicken necrotizing enterocolitis is prepared by the following raw materials in percentage by weight: 2-10 apramycin sulfate, 2-15 sodium orosulfan, 0.4-3 trimethoprim lactate, 0.1-0.5 atropine sulfate and the balance of tannic acid. The composition adopts two phytopathogenic components, i.e. the apramycin sulfate and the sodium orosulfan, wherein the apramycin sulfate taken orally is difficult to absorb andgenerates contact sterilization, the sodium orosulfan taken orally takes effect by humoral secretion, and pathogens are killed in two ways. The antibacterial effects of the apramycin sulfate and thesodium orosulfan are enhanced by the trimethoprim lactate, the atropine sulfate reduces glandular secretion, and the tannic acid forms a protective film with protein to prevent bacteria from contacting the intestinal canal and effectively protect the intestinal mucosa.

The invention relates to atropine sulfate eye drops, which comprise the following raw materials: atropine sulfate, sodium chloride, disodium hydrogen phosphate, sodium dihydrogen phosphate and water,the pH value of the atropine sulfate eye drops is 4.5-5.5, and the concentration of atropine sulfate is 0.09-0.11 mg/ml. The product has the advantages of simple formula, good stability, no stimulation to human eyes and simple preparation process, and is beneficial to long-term use.

The invention relates to the technical field of effective components of medicines, and in particular relates to a thin-layer determination method for atropine sulfate and diphenhydramine hydrochloridein a joint pain-relieving paste; the method comprises a thin-layer identification and measurement method of atropine sulfate and a thin-layer identification and measurement method of diphenhydraminehydrochloride. By aiming at the characteristics of all pharmaceutical ingredients in the joint pain-relieving paste, suitable extraction and preparation processes and needed preparations are providedbased on the thin-layer identification characteristics of atropine sulfate and diphenhydramine hydrochloride, so that components to be measured can be separated and extracted from a plurality of effective pharmaceutical ingredients of the joint pain-relieving paste to complete the thin-layer identification determination. The preparation method solves the problems that a relatively accurate resultcannot be obtained when atropine sulfate and diphenhydramine hydrochloride are singly extracted by the existing thin-layer identification and measurement method through medical effective ingredient analysis caused by the fact that sample coating in the traditional Chinese medicine and western medicine combination paste in the joint pain-relieving paste is all carried out at a high temperature, andall effective components are in colloid.

The invention discloses a nicotinic acid injection for treating heart diseases and a preparation method thereof. The nicotinic acid injection for treating heart diseases is prepared from pure essential oil, nicotinic acid, Span, a traditional Chinese medicine extracting solution, atropine sulfate and water for injection. The preparation method comprises the following steps: carrying out alcohol reflux extraction on radix salviae miltiorrhizae, kudzu root, lotus leaf and Inula, carrying out filter concentration and dialyzing to obtain the traditional Chinese medicine extracting solution; and proportionally mixing the traditional Chinese medicine extracting solution with the essential oil, nicotinic acid, Span and atropine sulfate, carrying out high-pressure steam sterilization, cooling and carrying out vacuum packaging. The nicotinic acid injection can be used for intravenous injection, has the advantages of high pharmacochemical stability, low toxicity and high drug specificity, has favorable curative effects on treating anemic cardiopathy, and has excellent animal experiment and clinical effects. The nicotinic acid injection is simple to prepare and low in cost, and has high practicality and important meanings for people with anemic cardiopathy.