1920results about How to "No pain" patented technology

A transdermal delivery device includes a plurality of microneedles for injecting a substance such as a pharmaceutical agent into or below the stratum corneum of the skin. The device has housing formed from a top and bottom wall to define a chamber for containing a pharmaceutical agent. An inlet port is provided in the top wall of the housing for supplying the pharmaceutical agent to the chamber and directing the agent to the microneedles. The housing can have a Luer lock type fitting for coupling with a syringe having a Luer lock collar to inject the pharmaceutical agent into the housing. The housing can be divided into a plurality of chambers by an internal wall for supplying different agents simultaneously or sequentially to a patient. The microneedles have a length of about 5–250 microns and generally about 50–100 microns.

A personal portable painless lancing device and a blood glucose meter using the same, which can lance at the minimum without any pain and use it to measure the blood glucose. The minimum painless lancing device using an Er:YAG laser includes an Er:YAG laser beam-generating section in which the laser beam is generated to punch skin and radiated in a single direction; an adapter installed at the front end of the Er:YAG laser beam-generating section so that the laser beam can be locally concentrated on a skin punch portion; a skin adhesion cap installed at the front end of the adapter so that it can be easily detached, and can reduce the contamination of the Er:YAG laser beam-generating section, which is produced at the time of the lancing, and the danger due to the reuse of it among the patients of lancing; and a case to accommodate the Er:YAG laser beam-generating section and the adapter therein.

A sensing apparatus and methods for measuring or detecting an analyte present in a biological system are provided. The methods entail use of the sensing apparatus that contains a reporter system specific for the analyte of interest, where the reporter system is either affixed to a planar backing or attached to particles that are delivered to the superficial layers of the skin. The reporter system includes a reporting reagent that absorbs or emits a detectable radiation and is placed in communication with the analyte, or in communication with tissue or body fluids suspected of containing the analyte. The sensing apparatus is illuminated, and a radiation signal from the reporting reagent is measured or detected and then associated with the presence or quantity of analyte.

This invention provides monitoring garments for non-invasively monitoring physiological parameters in un-restrained and/or restrained animals, such as monkeys, rabbits, dogs, horses, and the like. The invention also includes methods and systems for collecting and processing monitoring data.

A lightweight, portable, electrically-powered dermabrasive device adapted to gently and painlessly remove keratinized epidermal portions of the hands and feet. The dermabrasive device includes a protective shield which shields user against contact from flakes of flying or ejected epidermis or other detritus.

A syringe adapter with a ball-typed valve has a base, a dosing tube mounted around the base and a resilient valve mounted in the base and the dosing tube. The base has a guiding groove and an inner liquid channel communicating with each other, as well as an exhaust channel. Liquid medicine injected into the syringe adapter flows through the guiding groove and causes the inner liquid channel to be injected into a patient's body. The liquid medicine remaining in the split is cleaned when cleaning fluid is injected to clean the syringe adapter. Air in the syringe adapter flows out through the exhaust channel and is not injected into the patient's body, so the patient is free from pain. Furthermore, elements and assembling processes of the syringe adapter are simplified and manufacturing cost of the syringe adapter is lowered.

An imaging system comprising an imaging device assembled on a carrier tube, and a first outwardly expandable element and a second outwardly expandable element mounted on the carrier tube, wherein the second expandable element is expandable both radially and axially, the imaging system comprising a mode of operation, wherein during expansion of the second expandable element, obstruction of the radial expansion of the second expandable element causes the axial expansion of the second expandable element to propel the carrier tube and the imaging device axially.

A method of manufacturing a dressing (1) which incorporates a honey composition (7) and a base material (2) is disclosed. The method includes the steps of preparing the honey composition (7) and of the base material (2), characterised by a change in the physical characteristics of the base material (2). The dressing (1) may include additional agents (3) either in the honey composition (7) or the base material (7) or both. The dressing can include further layers further layers for adhesion; be covered with a waxed material and packaged. The dressing can be applied to a wide range of wounds including exudated and/or infected wounds.

The invention provides an acousto-optic sleep intervention system and method based on electroencephalogram signals. The method includes the steps: acquiring, processing and analyzing the electroencephalogram signals in real time during sleep through a universal electroencephalogram acquisition system; staging sleep by a data mining method; intervening through the sound and light in the REM (rapid-eye-movement) period of sleep and shallow sleep to achieve the purpose of improving sleep quality. The system includes a sleep electroencephalogram acquisition module, a sleep electroencephalogram staging module, and a sleep intervention module; the sleep electroencephalogram acquisition module is used to acquire the electroencephalogram signals that have continuously changed during sleep, the electroencephalogram signals after the output, and the extracted electroencephalogram characteristic information; the sleep electroencephalogram staging module is used to staging the sleep electroencephalogram characteristic information with trained sleep staging models; the sleep intervention module is used for selecting a suitable sleep intervention program based on the staging results, and the subject undergoes double intervention of sound and light.

A removable, adjustable intraoral apparatus having an upper plate and a lower plate, which, upon insertion into a user's mouth, cause advancement of the lower jaw relative to the upper jaw. One of either the lower plate or the upper plate can include length-adjustable blocks on the occlusal (biting) side thereof for causing further advancement of the lower jaw. Each length-adjustable block includes an advancement screw which is embedded in and extends from one of a pair of stationary raised block portions, and each of the plates without the embedded advancement screws also has a pair of raised block portions extending therefrom. The pairs of upper and lower blocks include contact surfaces which cooperate with each other to exert opposing forces upon the upper and lower dental arches and cause mandibular advancement. The length-adjustable portions allow for further mandibular advancement.

A personalized stereo health index measuring method and device features that the variation of multiple physiologic data in different psychological and spirits states of a person is monitored to indicate its health state and health potential.

A circumcision anastomat is structurally characterized in that a glans penis head is an oval cavity, the left side of the oval cavity is open, the top of the right end of the glans penis head is fixedly connected with the left end of a glans penis head pull rod, an angle of 45-90 degrees is formed between the head body center axis of the glans penis head and the plane of a glans penis head edge, clamping grooves are formed in the glans penis head edge, an elastic ring which is matched with the clamping grooves to be used is arranged in the clamping grooves, a circumcision body which can slide along the glans penis head pull rod is arranged on the glans penis head pull rod coaxially, a blade is arranged on the inner side of the circumcision body, a fixed handle is arranged on the circumcision body coaxially, a movable handle is connected with the left side of the fixed handle, the left end of the circumcision body is contacted with the movable handle through a damping piece, a reset spring and an insurance piece are connected between the movable handle and the fixed handle, a tractive rotary knob is arranged on the right side of the movable handle, and the right end of the glans penis head pull rod is connected with the tractive rotary knob through a threaded structure. By means of the circumcision anastomat, circumcision anastomose operations are simple, efficient, safe and fast, surgical wounds are smooth and attractive and are in conformity with normal anatomical structures and appearances, and requirements for postoperative care are low.

The invention provides a traditional Chinese medicine gastrointestinal auxiliary for type-B ultrasonic and a preparation method thereof, and the traditional Chinese medicine comprises the following raw medicinal materials: cumin, galangal, rhizome cyperi, three-nerved spicebush roots, cuttlebone, green tangerine peels, medicated leaven, malts, immature bitter orange, rheum officinale, mirabilite, cortex magnoliae officinalis, radix aucklandiae, amomum, agastache rugosa, finger citron, hawthorns, radish seeds, calcined concha arcae, evodia, pinellia ternate, semen arecae, atractylodes macrocephala koidz, rhizoma nardostachyos and fritillary bulb. The traditional Chinese medicine gastrointestinal auxiliary for type-B ultrasonic has the beneficial effects of being safe to use, painless, noninvasive, non-toxic, free from anaphylactic reaction, short in examination time, high in development rate, convenient to use and low in cost, providing a new technology and a new method for corrective early-stage diagnosis of diseases, and powerful basis for clinical diagnosis, and being a desirable novel auxiliary. Furthermore, the preparation process is simple and practical.

The object of the present invention is to provide footwear that exactly matches the feet of many people, the movement of a big toe inward and away from a second toe is not restricted, movement of the five toes is not limited, the base sections of the toes are stimulated, putting on the footwear is easy, the toes are made uncomfortable, and the footwear will not slip off even during fast walking. The footwear comprises a sole and instep covers formed of a soft material, wherein five openings and holes are provided on toe tip parts of the instep covers, the instep covers serve as guides, the five toes are led to the corresponding openings and holes, the five toes can easily protrude from the openings and holes, and broad sections between the openings and holes serve as straps.

Fat-dissolving oil of Chinese herbal medicine for weight loss and preparation method thereof. It belongs to a slimming beauty product and a preparation method thereof. It is based on honeysuckle, lotus leaf, hawthorn, cassia seed, saponin leaves, hemp seed, radish seed, tangerine peel, fleece-flower root, licorice, aurantium, guarana, evening primrose, safflower, ginger, pepper, wild pepper, corn Mustard, Tianqi, mulberry leaf, mulberry, wolfberry, Codonopsis, rhubarb, angelica, lovage, salvia, yam, turmeric, Daxueteng, mugwort, antler, ginseng, Kochia, cabbage, castor bean, raspberry, Atractylodes, Coptidis, Alisma, white peony, radish skin, mirabilite, astragalus, capers, morning glory, euphorbia, and ephedra are crushed, mixed with olive oil, heated and decocted, and the residue is filtered off. When using it, apply it evenly on the parts that need to lose weight and melt fat, and massage repeatedly until the skin is hot. The formula of the invention is scientific and reasonable, convenient to use, non-irritating and painless to the skin, has no side effect on the human body and can exert long-term effect, and enhance skin elasticity and gloss.

The invention discloses a blood flowing detection device and method. The detection device comprises an inflation pressure binding belt, a detection host, as well as a temperature sensor and a humidity sensor which are connected with the detection host; and the detection host comprises a control button, a switching voltage-stabilized power supply circuit, a singlechip microcomputer central control-processing unit, a preamplifier, an A/D (analog-to-digital) conversion circuit, a display and a buzzer. The detection method comprises the following steps: releasing restriction after a blood flow atthe proximal end of a heart is restrained for a certain period of time; measuring changes of skin temperature and humidity on a position at a distal end of the heart, and comparing the changes with the standard parameters of people with a normal blood flowing condition; determining whether a testee has vascular endothelial dysfunction or not; and evaluating the severity of early symptoms of cardiovascular sclerosis and hemodynamics of the testee. The detection device has the advantages of simple structure, low cost and convenience for operation, causes no trauma or pain, and can be used for routine physical examination and community general examination.

The invention discloses an automated training device for behavior learning of non-human primates, wherein a personal computer (PC) is provided with two displays, wherein one of the displays and a camera are respectively positioned in front of an animal seat; a water supply control system comprises a water receiver, a driving control circuit and an electromagnetic valve, wherein the water receiver is connected with the electromagnetic valve through a guide tube, the electromagnetic valve is electrically connected with the driving control circuit, and the driving control circuit is electrically connected with a microcontroller; a swinging rod and a water faucet are fixed on the animal seat, a pressure sensor is fixed on a handle of the swinging rod, the pressure sensor and a potentiometer of the swinging rod are electrically connected with the microcontroller respectively, and the water faucet is connected with the electromagnetic valve of the water supply control system through the guide tube; and the PC is electrically connected with the camera and the microcontroller respectively. The invention can realize a painless automated animal behavior training method, and the camera can be used for displaying and monitoring the animal behavior in real time, thereby greatly improving the training speed and saving human resources.

The invention relates to a device and a method for treating tumors through irreversible electroporation, belonging to the technical field of tumor treatment. The device mainly comprises a square wave pulse generation and measurement system, a signal conversion system, a man-machine communication system, a measurement control system and a power supply system. In the method, the device and a therapeutic electrode are used for treating the tumors through a program. Under the circumstance of no injection of chemotherapeutic drugs, microsecond square wave pulses are applied to tumor tissues, the entire tumor cell is fully damaged, so that the tumor cell dies due to irreversible electroporation, and the harm on the body of a patient caused by the side effect of the chemotherapeutic drugs is radically avoided. The invention has the characteristics of short treatment time, no pain, good treatment effect, high safety, convenient use, simple operation, convenient popularization and application and the like. The device and the method can be widely used for treating the tumors of human and animals, and are especially applicable to human tumor treatment.