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Traditional Chinese medicine gastrointestinal auxiliary for type-B ultrasonic and preparation method thereof

A technology of contrast aids and traditional Chinese medicines, which is applied in medical formulas, echo/ultrasonic imaging agents, medical preparations containing active ingredients, etc., and can solve problems such as no therapeutic effect, affected imaging effects, and discomfort

Inactive Publication Date: 2013-03-06
王玉云
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, for B-ultrasound gastrointestinal imaging aids, the prior art has recorded an imaging aid prepared by mixing 80% of octopus fine powder and 20% of bletilla striata 100-mesh fine powder, which has astringent and acid-stopping effects on gastrointestinal diseases , but the disadvantage is that the strong echo light spot produced by the patient after taking the contrast agent is insufficient, the reflection effect is not good, and the layer of the stomach wall is not displayed clearly; after the patient takes the contrast agent, the gastric acid reaction is strong, and there is pain and discomfort. It is beneficial for contrast-enhanced ultrasound of the gastrointestinal tract, and this contrast agent cannot be used for patients with gastric bleeding
The prescription uses bitter barrels, which taste extremely bitter, so sucrose is used to improve the taste, and sucrose easily produces bubbles when it enters the gastric juice, which affects the imaging effect. In addition, the product of this invention has no therapeutic effect

Method used

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Experimental program
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Effect test

preparation example Construction

[0069] The present invention further provides a method for preparing the above-mentioned traditional Chinese medicine gastrointestinal contrast aid for B-ultrasound, the dosage form of the traditional Chinese medicine contrast aid is granule, which comprises the following steps:

[0070] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 4 to 6 times that of the mixture and 85% to 95% ethanol, heat to boiling and reflux for 3 to 5 hours, filter, and use percolation to remove Slowly percolate at a speed of 1-2ml per minute, collect the percolation liquid, then concentrate under reduced pressure at a vacuum of 0.06-0.09Mpa to a paste with a relative density of 1.04-1.10 at 50-60°C, spray dry, spray dry The air inlet temperature of the machine is 160-175°C, and the outlet air temperature is 80-85°C, and then crushed into powder to make dry cream powder;

[0071] Step 2: Add 0.2-0.4 times of sucrose powder and 0.1-0....

Embodiment 1

[0084] Embodiment 1: the granule prepared by the present invention

[0085] 19g cumin, 19g galangal, 12g Cyperus cyperi, 12g black yao, 20g sea octopus, 22g green skin, 16g divine music, 12g malt, 13g citrus aurantium, 18g rhubarb, 15g mirabilite, 16g magnolia bark, 22g woody fragrance, amomum 15g, Huoxiang 10g, Bergamot 12g, Hawthorn 20g, Cabbage 15g, Calcined Corrugated Seed 18g, Evodia 10g, Pinellia 16g, Areca 12g, Atractylodes 7g, Gansong 11g and Fritillaria 15g.

[0086] Its preparation method comprises the following steps:

[0087] Step 1: Mix all raw medicinal materials according to the above ratio, add ethanol with an alcohol concentration of 85% that is 5 times that of the mixture, heat to boiling and reflux for 4 hours, filter, and slowly percolate at a rate of 2ml per minute by percolation method , collect the percolation liquid, then concentrate under reduced pressure at 0.08Mpa to a paste with a relative density of 1.10 at 60°C, spray dry, the air inlet temperatu...

Embodiment 2

[0089] Embodiment 2: the capsule prepared by the present invention

[0090]20g cumin, 20g galangal, 10g Cyperus cyperi, 13g black yao, 18g sea octopus, 20g green bark, 15g divine song, 15g malt, 10g citrus aurantium, 19g rhubarb, 14g mirabilite, 15g magnolia bark, 20g woody fragrance, amomum 18g, Huoxiang 12g, Bergamot 14g, Hawthorn 25g, Cabbage 16g, Calcined Corrugated Seed 16g, Evodia 8g, Pinellia 15g, Areca 10g, Atractylodes macrocephala 6g, Gansong 12g and Fritillaria 16g.

[0091] Its preparation method comprises the following steps:

[0092] In the first step, mix cumin, galangal, wrinkled wrinkle, Cyperus cyperi, black medicine, cabbage seed, divine comedy, malt, hawthorn and green bark according to the above ratio, add 6 times of water to the mixture to extract the volatile oil, and extract the obtained The volatile oil is clathrated with β-cyclodextrin, the ratio of volatile oil to β-cyclodextrin is 1:5, stirred for 80 minutes, the temperature is 40°C, the volatile o...

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PUM

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Abstract

The invention provides a traditional Chinese medicine gastrointestinal auxiliary for type-B ultrasonic and a preparation method thereof, and the traditional Chinese medicine comprises the following raw medicinal materials: cumin, galangal, rhizome cyperi, three-nerved spicebush roots, cuttlebone, green tangerine peels, medicated leaven, malts, immature bitter orange, rheum officinale, mirabilite, cortex magnoliae officinalis, radix aucklandiae, amomum, agastache rugosa, finger citron, hawthorns, radish seeds, calcined concha arcae, evodia, pinellia ternate, semen arecae, atractylodes macrocephala koidz, rhizoma nardostachyos and fritillary bulb. The traditional Chinese medicine gastrointestinal auxiliary for type-B ultrasonic has the beneficial effects of being safe to use, painless, noninvasive, non-toxic, free from anaphylactic reaction, short in examination time, high in development rate, convenient to use and low in cost, providing a new technology and a new method for corrective early-stage diagnosis of diseases, and powerful basis for clinical diagnosis, and being a desirable novel auxiliary. Furthermore, the preparation process is simple and practical.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine engineering, in particular to a traditional Chinese medicine gastrointestinal imaging aid for B-ultrasound and a preparation method thereof. Background technique [0002] Ultrasound image diagnosis is one of the important diagnostic methods in medicine. Ultrasound has three major effects on matter: one is mechanical action, because the ultrasonic energy is huge, it often makes the material particles vibrate at high frequency mechanically, thus producing crushing, agglomeration, and stirring effects. The second is the thermal effect. When the ultrasonic wave acts on the substance, its energy is absorbed by the substance, thus increasing the temperature of the substance. The third is cavitation. When the ultrasonic wave acts on the liquid, the area with weak internal stress in the liquid (such as microscopic bubbles, etc.) becomes sparse due to the huge change in the sound pres...

Claims

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Application Information

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IPC IPC(8): A61K49/22A61K36/9064A61P1/00A61K35/56A61K33/04A61K35/618
Inventor 王玉云王永萍
Owner 王玉云
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