The invention relates to pyrus ussuriensis cough syrup raw material medicinal powder and application thereof. The pyrus ussuriensis cough syrup raw material medicinal powder comprises, by weight, 13-17 parts of semen benincasae, 13-17 parts of reed stem, 8-12 parts of almond, 7-11 parts of prepared ephedra, 4-8 parts of radix glycyrrhizae, 8-12 parts of radix peucedani, 8-12 parts of radix stemonae, 8-12 parts of fritillaria cirrhosa, 13-17 parts of Trichosanthes kirilowii Maxim, 8-12 parts of prepared loquat leaf, 10-14 parts of honeysuckle, 13-17 parts of taraxacum mongolicum, 28-32 parts ofherba houttuyniae, 8-12 parts of radix scutellariae, 13-17 parts of folium isatidis, 8-12 parts of fructus forsythia, 4-8 parts of arisaema cum bile, 13-17 parts of radix polygonati officinalis, 13-17 parts of radix trichosanthis, 8-12 parts of radix asparagi and radix ophiopogonis, 2-5 parts of agilawood powder, 7-11 parts of ginkgo, 8-12 parts of perillaseed, 8-12 parts of semen raphani, 8-12 parts of Schisandra chinensis, 8-12 parts of rhizoma belamcandae, 8-12 parts of fructus arctii, 13-17 parts of radix isatidis, 7-11 parts of radix sophorae tonkinensis, 2-5 parts of asarum, 7-11 partsof ramulus cinnamomi, 4-8 parts of rhizoma zingiberis, 8-12 parts of ginger processed pinellia, 13-17 parts of agrimonia pilosa ledeb, 13-17 parts of Perotis indica, 13-17 parts of raw Platycladus orientalis and 1-5 parts of panax notoginseng powder. The pyrus ussuriensis cough syrup raw material medicinal powder is mainly used for moistening the lung, relieving cough, reducing phlegm and treatingcough, expectoration, bronchitis and emphysema and is evident in effect and good in safety.