The invention relates to an externally-applied plaster with the functions of detoxifying and promoting tissue regeneration. In the invention, angelica, dahurian 
angelica root, radix arnebiae seu lithospermi, 
astragalus root, radix salviae miltiorrhizae and sward are put into 
sesame oil and soaked, the 
sesame oil is heated to cause the traditional Chinese medicines in the 
sesame oil to be burnt into carbon, 
medicine residues are filtered out, mercurous 
chloride, red lead, mastic, 
myrrh and draconis sanguis are sequentially added into the sesame oil, the sesame oil is stirred and heated until the sesame oil does not fume any longer, 
centipede and scorpio are added into the sesame oil after the sesame oil is cooled, and then the sesame oil is evenly stirred to prepare the externally-applied plaster. The 
medicine is mainly used for treating diseases, such as various ulcers, purulent ulcers, bedsores, no 
concrescence of wounds for a long time after operation and the like, has the functions of resisting 
bacteria, diminishing 
inflammation, decreasing swelling, alleviating pain, promoting 
blood circulation, relieving the stasis of blood and reinforcing the bacteriostasis and sterilization capabilities of wound faces, improves the 
microcirculation of ulcer positions, induces the exudation of the nutritive tissue liquid of organisms, restores the effective ingredients of 
organism tissues and has the effects of removing putrescence, promoting tissue generation, eliminating putrescence and promoting tissue regeneration. By clinical observation, the total effective rate reaches 95%.