18 results about "Abdomen diseases" patented technology

The invention discloses a long-acting pellet suitable for gastric absorption and a preparation method of the long-acting pellet. The long-acting pellet is prepared from the following components in parts by mass: 0.01-1 part of a medicine, 1-2.5 parts of a filler, 0.2-0.7 part of a modified pore-foaming agent mixture, 1-2.5 parts of an improved adhesive mixture and 0.1-0.7 part of an improved sonokinetic response agent. Wherein the modified pore-foaming agent mixture is prepared from a modified pore-foaming agent and glycosylated saponin, the modified pore-foaming agent is prepared by mixing a pore-foaming agent and seleno-amino acid according to a mass ratio of 4: 1, the improved adhesive is mixed with the adhesive through BHP-SH, and ionic crosslinking is performed by using CaCl2 to form a covalent ion dual network, so that the stomach adhesiveness is enhanced; the sonokinetic response agent is improved by the coated poria cocos extract, and the long-acting pellet is prepared by adopting a wet granulation method or a fluidized bed method, has the characteristics of slow release, long acting, targeted stomach absorption and responsive drug release, and is suitable for treating stomach diseases such as gastritis.

The non-medicine non-acupuncture method for treating the old stomach disease is simpler than common medicine acupuncture treatment, the old stomach disease can be treated indeed, ginger can be used or not used, medicine can be completely not used, and a physical treatment method which seems to be more effective substantially is provided by the method and the device for treating the stomach disease through live-time exchange. And the time and the device are optimized to fulfill the aim.

The invention is suitable for the technical field of medicine, and provides a stomach medicine capsule and a preparation method thereof, the stomach medicine capsule is prepared from 20-30 parts of Chinese angelica, 7-11 parts of phoenix-tail fern, 15-19 parts of radix berberidis, 5-9 parts of radix aucklandiae, 2-4 parts of reed seed, 13-17 parts of sea snail and auxiliary materials; the preparation method comprises the steps of raw material pretreatment, ethanol reflux extraction, vacuum concentration, spray drying, mixing granulation, capsule filling and packaging. The traditional Chinese medicine raw materials in a specific proportion are screened, the synergistic effect of resisting inflammation and bacteria, regulating qi to relieve pain, nourishing blood and repairing, and relieving acid and protecting the stomach is achieved, and the problems that an existing stomach medicine is single in effect and large in side effect are solved; meanwhile, extraction and drying processes are optimized, the dissolution rate of effective components and the stability of the preparation are improved, and the traditional Chinese medicine composition is suitable for treating stomach diseases such as acute and chronic gastritis, gastric ulcer and hyperacidity, high in safety and suitable for long-term administration.

The invention discloses a preparation method and application of a probiotic-loaded hydrogel precursor solution for treating stomach diseases, and belongs to the field of preparation of medicinal high polymer materials. Comprising the following steps: oxidizing hyaluronic acid with sodium periodate to obtain oxidized hyaluronic acid; reacting the oxidized hyaluronic acid with dopamine to prepare dopamine modified oxidized hyaluronic acid; the preparation method comprises the following steps: carrying out amidation reaction on chitosan and N-acetyl-L-cysteine to prepare thiolated chitosan; the preparation method comprises the following steps: mixing dopamine modified oxidized hyaluronic acid and a thiolated chitosan aqueous solution with probiotics, and carrying out a cross-linking reaction under oxidation and acidic conditions to obtain a hydrogel precursor solution; the hydrogel precursor solution can be taken orally and swallowed, can be further gelatinized in situ under the condition of stomach focus oxidation, has excellent adhesion, and can be effectively retained in the stomach and keep the activity of probiotics. In addition, the hydrogel can continuously remove excessive active oxygen in the stomach, relieve the inflammatory response of gastric mucosa and remarkably improve the microenvironment of the focus.

The invention relates to the technical field of traditional Chinese medicine, and particularly discloses a traditional Chinese medicine composition for treating different syndrome types of stomach diseases and a preparation method thereof.The traditional Chinese medicine composition is prepared from, by weight, 15-25 parts of fried szechwan chinaberry fruit, 8-12 parts of radix bupleuri and 15-35 parts of fried fructus perillae. The traditional Chinese medicine composition is prepared from 40-60 parts of trogopterus dung, 15-35 parts of herba patriniae, 8-12 parts of radix scutellariae, 15-25 parts of radix codonopsis, 30-50 parts of fructus jujubae, 15-25 parts of radix paeoniae alba, 15-25 parts of pericarpium citri reticulatae, 2-6 parts of radix et rhizoma rhei, 8-12 parts of radix glycyrrhizae preparata and 10-35 parts of herba agrimoniae. The traditional Chinese medicine further comprises 15-35 parts of cuttlebone, 3-5 parts of calcined concha arcae, 40-60 parts of trogopterus dung, 8-12 parts of roasted rhizoma atractylodis macrocephalae, 15-25 parts of poria cocos, 4-8 parts of Chinese prickly ash, 8-12 parts of fructus amomi, 8-12 parts of fructus amomi rotundus and 5-10 parts of fructus evodiae. A complementary treatment system is formed for the four clinical common syndromes of spleen and stomach qi deficiency and water dampness, cold-dampness and qi stagnation and cold-heat intermingling, liver-stomach disharmony, cold-heat intermingling type reflux disease and phlegm-blood stasis type gastric polyp respectively and accurately.

The invention belongs to the technical field of medicines, and particularly relates to application of hibiscus (the hibiscus is a plant hibiscus flower and an extract and an active monomer thereof) in preparation of medicines for treating stomach diseases (atrophic gastritis, gastric mucosal lesion and gastric cancer). The invention discloses application of hibiscus syriacus in treatment of gastric diseases. The application comprises at least one of chronic atrophic gastritis treatment, gastric mucosa protection and gastric cancer prevention. In-vitro experiments show that the shrub althea flower extract, shrub althea flower polyphenol, syringic acid (I), protocatechuic acid (II), kaempferol (III) and kaempferol-7-O-beta-D-glucoside (IV) have obvious antioxidant activity and gastric mucosa protection activity, can obviously reduce the ROS content in ethanol-induced GES-1 cells and the expression of apoptosis marker protein Caspase-3 / Bax, and have a wide application prospect.

The application discloses a short-wave ultraviolet irradiation-based stomach disease treatment instrument, and belongs to the technical field of medical equipment.The application comprises a treatment instrument main body, a main pipe body, a probe end, an ultraviolet emission end and a treatment control module for controlling the treatment instrument main body; the modular design of the treatment instrument main body and the combination with the ultraviolet emission end improve the clinical operability and treatment effect, the combination with the rotary toothed disc driving mechanism enables the ultraviolet emission end to realize all-around twisting, covers the stomach area, the light-transmitting layer blocks infrared radiation while ensuring the ultraviolet transmittance, reduces the thermal stimulation on the stomach tissue, and enables medical staff to observe the irradiation effect in real time, realizes visual treatment, the treatment control module realizes the precision and intelligence of stomach disease treatment through a multi-unit cooperative architecture, generates a personalized scheme based on the disease type and the lesion position, monitors the physiological indexes of patients in real time and dynamically adjusts the treatment parameters, and improves the treatment safety and effectiveness.

The utility model relates to the technical field of medical supplies, in particular to a gastroscopy bag for stomach illness examination, which comprises a gastroscopy bag bottom, a dust cover, a liner, a waterproof film and a T-shaped partition plate, the dust cover is arranged at the top of the gastroscopy bag bottom, a built-in tray is arranged on one side of the T-shaped partition plate, and the waterproof film is arranged on the other side of the T-shaped partition plate. A liner made of medical-grade non-woven fabric is arranged at the inner bottom of the built-in tray; a T-shaped partition plate is fixed in the dustproof cover, a first inserting groove is formed in the bottom of the gastroscopy bag bottom, and a second inserting groove is formed in the inner side of the dustproof cover; the novel gastroscopy bag is provided with a structure for carrying out anti-collision and anti-abrasion protection on the gastroscope, damage to the gastroscope in the process of taking and placing the gastroscope is avoided, the function of preventing water or corrosive liquid from permeating into the gastroscopy bag from the bottom of the gastroscopy bag is achieved, and then the practicability can be effectively improved.

The utility model provides a spleen and stomach disease meridian knocking physiotherapy device, which comprises a shell, a knocking assembly, an arc-shaped cover plate, an arc-shaped plate holding strip and two flexible ribbons, and is characterized in that the knocking assembly is arranged in the shell and penetrates through the shell downwards; the arc-shaped cover plate is connected to the side part of the shell, extends towards the outer side and is used for covering the periphery of the back of a hand; the two ends of the arc-shaped plate holding strip are connected to the edges of the two sides of the opening side of the arc-shaped cover plate respectively, protrude towards the side away from the arc-shaped cover plate in an arc-shaped mode and are used for being held by a patient. The two flexible ribbons are connected to the edges of the two sides of the opening side of the arc-shaped cover plate correspondingly and located on the side, away from the shell, of the arc-shaped plate holding strip, and the two flexible ribbons are connected through hook-and-loop fasteners. According to the spleen and stomach disease meridian knocking physical therapy device provided by the utility model, the arc-shaped cover plate can be fixed on the arm through the matching of the magic tape and the two flexible ribbons, so that the knocking physical therapy device is prevented from being separated from the hand to be broken in the use process.

The invention discloses a spleen and stomach disease meridian knocking physical therapy device, and belongs to the technical field of health care instruments, the spleen and stomach disease meridian knocking physical therapy device comprises a shell mechanism, and the interior of the shell mechanism is fixedly connected with a guide rail mechanism. Through the design of the multiple sets of supporting side plates, the knocking rolling wheels and the knocking protruding blocks and in combination with rotating transmission of the rotating shaft assembly, multi-angle and continuous knocking physical therapy on related meridians and collaterals of the spleen and the stomach is achieved, the meridian stimulation effect is enhanced, and compared with limitation of single-point or local knocking of existing partial physical therapy devices, the physical therapy effect is improved. The two sets of supporting side plates on the outer side of the supporting plate drive the corresponding knocking rolling wheels to rotate, the knocking protruding blocks on the peripheries of the knocking rolling wheels are distributed in an annular array mode, and under driving of the rotating shaft assembly, comprehensive and continuous knocking stimulation can be conducted on multiple meridians (such as meridian areas corresponding to Zhongwan and Zusanli) related to the spleen and the stomach of the abdomen; the effect of regulating qi and blood circulation of the spleen and the stomach through meridian physiotherapy is fully exerted, the spleen and stomach function is improved in an auxiliary mode, and the auxiliary treatment and prevention effects on spleen and stomach diseases are more remarkable.

The present application relates to the technical field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for treating stomach diseases, which is prepared from 23-25 grams of lily, 8-10 grams of magnolia officinalis, 8-10 grams of corydalis, 5-7 grams of melia toosendan, 5-7 grams of galangal, 8-10 grams of rhizoma cyperi, 23-25 grams of fried white peony root, 5-7 grams of licorice, 5-7 grams of coptis, 1-3 grams of evodia, 10-14 grams of salvia miltiorrhiza, 2-4 grams of sandalwood, and 5-7 grams of amomum villosum. The traditional Chinese medicine composition for treating stomach diseases is prepared by mixing the above-mentioned raw materials, adding 400 ml of water, boiling, and then continuing to decoct for 30 minutes, filtering the extracted medicinal liquid, adding 400 ml of water to the residue, boiling, and then continuing to decoct for 30 minutes, filtering the extracted medicinal liquid, and combining the two times of extracted medicinal liquid. The traditional Chinese medicine composition for treating stomach diseases is used for treating bile regurgitation gastritis of the type of liver depression and blood stasis, and has the effects of regulating cold and heat and regulating qi and blood.

The invention relates to the technical field of scheme recommendation, in particular to a spleen and stomach disease traditional Chinese medicine acupoint combined physical rehabilitation treatment scheme generation system and method. The method comprises the following steps: collecting core symptom score data of a patient during each face diagnosis; the digestion, transportation and transformation load degree is obtained according to the eating discomfort score in combination with other symptom compensation adjustment; analyzing a function recovery response rate based on historical time sequence data, and constructing a multi-dimensional conditioning demand vector in four dimensions of tonifying, dredging, warming and conditioning through a qi movement retardation coefficient calculated through first face diagnosis symptom data; historical patients are matched based on vector similarity, and reference auxiliary schemes are screened in combination with digestion transportation and transformation load degree approximation. According to the method, the functional demand targets of the patients are summarized into the directions of supplementing, dredging, warming and reconciling, the matching conditions of the current patients and the historical patients in the functional demand directions are analyzed for scheme recommendation, standardized and individualized generation of the scheme is guaranteed, and the reliability and repeatability of the scheme are improved.

The invention provides a transdermal absorption ointment for treating stomach diseases and a preparation method thereof, and belongs to the technical field of medicines. The preparation method comprises the following steps: modifying n-docosyl-coated calcium carbonate phase change microspheres through polydopamine, coupling the modified microspheres to arginine nonamer modified chitosan, reacting with chlorinated beta-cyclodextrin for grafting, adding enzyme extracts of cinnamon, cardamom, fennel, rhizoma zingiberis and fructus evodiae, stirring for inclusion, and adding genipin for crosslinking to prepare the percutaneous absorption ointment for treating stomach diseases. The percutaneous absorption ointment for treating stomach diseases prepared by the invention is well attached to the skin, a patient feels comfortable after being attached, the compliance is high, the percutaneous absorption ointment is superior to the traditional Chinese medicine glue ointment, the percutaneous absorption ointment directly enters systemic circulation through percutaneous absorption, gastric acid damage and liver metabolism are avoided, and the bioavailability is better.

The invention discloses a rapidly-dissolved finasteride tablet and a production method thereof, and relates to the technical field of medicine preparation. According to the invention, finasteride is loaded in carboxylated mesoporous silica, so that drug molecules of finasteride are dispersed from a crystalline state to an amorphous state, the dissolution rate is improved, carboxyl maintains a non-ionized state in a gastric juice environment, stimulation of drugs in a gastric acid environment is reduced, carboxyl is ionized in an intestinal solution, and the dissolution rate of the drugs is increased. The quick release of the medicine can be realized; according to the invention, a modified polymer emulsion is also prepared as a material of a coating solution, by utilizing the characteristics of the coating solution, the tablet is insoluble in a gastric acid environment and dissolved in an intestinal juice environment, the irritation to patients with stomach diseases is reduced, and the intestinal absorption area is relatively large, so that the absorption rate of the medicine is improved, and the bioavailability is improved.

The invention relates to the field of traditional Chinese medicine formulas, and particularly discloses a traditional Chinese medicine formula for treating stomach diseases and a preparation method and application thereof. The invention discloses a traditional Chinese medicine formula for treating stomach diseases. The traditional Chinese medicine formula comprises the following components by weight: 5-15g of deep-fried bighead atractylodes rhizome, 3-10g of cassia twig, 10-15g of rice sprout, 1.5-5g of coptis chinensis, 3-15g of fructus forsythiae, 15-30g of dandelion, 3-10g of mangnolia officinalis, 1-3g of agilawood, 15-30g of astragalus membranaceus, 3-9g of poria cocos, 3-9g of elecampane, 3-9g of fingered citron, 3-10g of octopus, 10-15g of pearl, 3-10g of pericarpium citri reticulatae, 3-9g of frankincense, 3-9g of myrrh, 5-10g of trogopterus dung, 3-9g of stigma croci, 10-15g of red yeast rice, 2-10g of liquorice, 3-9g The traditional Chinese medicine is prepared from 0.5-1.0 g of benzoin, 0.03-1 g of borneol, 6-15 g of radix salviae miltiorrhizae, 3-9 g of radix curcumae, 1-3 g of clove, 3-6 g of amomum cardamomum, 3-10 g of rhizoma nardostachyos, 3-9 g of Chinese yam, 5-10 g of radix paeoniae alba, 3-9 g of curcuma zedoary and a small amount The preparation method of the Sanwei capsule comprises the following steps: S1, preparing thick paste; s2, grinding into powder; s3, performing granulation; and S4, preparing the capsule. The Sanwei powder and the Sanwei capsule can be used for treating various types of gastritis, gastric ulcer and gastric erosion, and have the advantages of good effect and small side effect.

The invention provides a fermented traditional Chinese medicine formula for preventing African swine fever and a preparation process thereof. The fermented traditional Chinese medicine formula is prepared from the following materials in parts by weight: 8-15 parts of herba houttuyniae, 5-10 parts of radix scutellariae, 10-15 parts of liquorice root, 10-20 parts of herba violae, 11-15 parts of flos puerariae, 10-15 parts of honeysuckle flower, 8-10 parts of rhizoma coptidis, 10-15 parts of rhizoma zingiberis, 8-15 parts of evodia lepta, 10-15 parts of peperomia blanda, 6-9 parts of rhizoma atractylodis macrocephalae, 10-15 parts of oldenlandia diffusa and 8-10 parts of herba scutellariae barbatae. The preparation method comprises the following preparation steps: step 1, cleaning the raw materials with clear water, putting the cleaned raw materials into a fermentation tank, fermenting the traditional Chinese medicine raw materials to eliminate the internal toxicity of part of traditional Chinese medicines, combining the traditional Chinese medicine formula with daily feed for pigs and drinking water according to the pathogenesis of the swine fever to achieve the effects of sterilizing, killing insects, clearing away heat and toxic materials, and improving the immunity of the swine; from the aspect of preventing respiratory tract, intestinal tract, throat and stomach diseases, the hog cholera problem is solved by preventing the hog cholera in advance.

The invention discloses a preparation method of diclofenac sodium delayed sustained-release tablets, which comprises the following steps: S1, uniformly mixing diclofenac sodium, a waxy sustained-release material and a high-molecular retardant material, then transferring the mixture into a melting spheronization pelleting machine, heating and stirring, extruding the mixture into strips through a screw extruder, and then preparing sustained-release pellets on a spheronization machine; s2, preparing a suspension solution from an enteric material, a plasticizing material, a lubricating material and a solvent, transferring the sustained-release pellets into a fluidized bed, atomizing the suspension solution, spraying the atomized suspension solution on the surfaces of the sustained-release pellets, and heating, ventilating and drying to obtain enteric sustained-release pellets; and S3, uniformly stirring and mixing the enteric-coated sustained-release pellets, a filling agent, a flow aid and a lubricating agent, and pressing on a tablet press to obtain the diclofenac sodium delayed sustained-release tablet. The medicine can be prevented from being released in the stomach, the problem of irritation to the stomach is avoided, the safety of the medicine in the aspect of gastrointestinal tracts is greatly improved, and the medicine is more suitable for being taken by patients with gastric diseases.

This invention relates to the field of medical natural language processing and knowledge graph construction, and particularly to a method for entity relation extraction and knowledge graph construction for traditional Chinese medicine (TCM) spleen and stomach diseases. The method includes: S1, constructing a training corpus; S2, constructing a joint entity relation extraction model; S3, initializing the joint entity relation extraction model with BERT and RoBERTa pre-training parameters respectively, and training it using the training corpus to obtain a first model and a second model; S4, preprocessing unlabeled text and inputting it into the first and second models respectively to obtain a first candidate triplet set and a second candidate triplet set; S5, fusing the first and second candidate triplet sets; S6, performing strong correlation screening; and S7, performing post-processing to obtain normalized triplets and importing them into a graph database to construct or update a TCM spleen and stomach disease knowledge graph. This method avoids error cascading and constructs a high-fidelity, low-redundancy, and interpretable TCM spleen and stomach disease knowledge graph.