The invention particularly relates to a method for cultivating Chinese medicinal health care product ganoderma and health preservation liquid thereof by conventional biotechnology, which has the following raw material formulation: asparagus root, ginseng, rehmannia root, dried longan pulp, acanthopanax root bark, Chinese magnoliavine fruit, yam, hawthorn, Chinese date, garlic, radix achyranthis bidentatae, chrysanthemum, Chinese wolfberry, coixseed, glossy ganoderma, fiveleaf gynostemma herb, dried ginger, mushroom, liquorice root, cordyceps, epimedium herb, tea leaf, safflower, malt, medicated leaven, dark plum fruit, tangerine peel, solanum dulcamara L., sweet potato starch, figwort root, perilla leaf, white mustard seed, galangal root, sugar, milk powder, ginkgo leaf, pure water and white liquor. The prepared health care product has the main functions of tonifying the kidney, nourishing the liver, tonifying the spleen, harmonizing stomach, benefiting heart and lung, moisturizing dryheat by clearing the bowels, and the like, supplementing the lacking elements of human body, removing excess absorption, and bidirectionally regulating metabolism and immune functions, is suitable for diabetes, cardiovascular and cerebrovascular diseases, tumor, hypertension, obesity, and liver, gall, intestine and stomach diseases, anorexia, hypodynamia, constipation, and the like, has no any toxic or side effect, and is suitable for male, female, the old and the young.