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Medicine for treating osteoporosis and preparing method

A technology for osteoporosis and drugs, applied in the field of drugs for the treatment of osteoporosis and its preparation, can solve the problems of unsatisfactory curative effect, high price, and many adverse reactions of bisphosphonate drugs, and achieve remarkable curative effect, Effect without toxic side effects

Inactive Publication Date: 2006-08-09
张凌芸
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 1 Long-term use of high-dose calcium + vitamin D has high complications and poor curative effect
[0006] 2Sex hormones are potentially carcinogenic
[0007] 3 Calcitonin can only be administered parenterally, which is expensive, and it remains to be seen whether it can be administered for a long time
[0008] 4 There are many adverse reactions of bisphosphonates, and the effect of single application is not ideal
[0009] Although there are also some Chinese patent medicines for the treatment of osteoporosis, Chinese medicine calcium preparations, or Chinese patent medicines with functions of promoting blood circulation and removing blood stasis, reducing swelling and relieving pain, relaxing tendons and strengthening bones, warming and tonifying kidney yang, etc., but because of their single function, the curative effect is not satisfactory.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] For the medicine for treating osteoporosis, the optimum weight ratio of its raw materials is:

[0028] Epimedium 1167g Dipsacus 167g Salvia 83g

[0029] Anemarrhena 83g Psoralen 83g Rehmannia 83g

[0030] Above-mentioned dosage form is the processing step of the preparation method of tablet as follows:

[0031] (1), crush the salvia miltiorrhiza into fine powder, sieve, and set aside;

[0032] (2) Crush Epimedium, Dipsacus, Anemarrhena, and Psoralen into coarse powder, cut Rehmannia glutinosa into pieces, add water and boil three times, the first time is 3 hours, the first time is 2 hours, the first time is 1 hour , combine the decoction, filter, concentrate the filtrate to a clear paste with a relative density of 1.20, add the salvia miltiorrhiza powder prepared in step (1), mix well, make granules, dry, compress into tablets, and coat with film.

Embodiment 2

[0034] Weigh the raw materials according to the following ratio:

[0035] Epimedium 1027g Dipsacus 147g Salvia 73g

[0036] Anemarrhena 73g Psoralen 73g Rehmannia 73g

[0037] Its preparation process is identical with embodiment 1.

Embodiment 3

[0039] Weigh the raw materials according to the following ratio:

[0040] Epimedium 1307g Dipsacus 187g Salvia 93g

[0041] Anemarrhena 93g Psoralen 93g Rehmannia 93g

[0042] Its preparation process is identical with embodiment 1.

[0043] Of course, the present invention can also be prepared into any dosage form described in pharmacy, such as capsules, granules and other dosage forms.

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PUM

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Abstract

The invention relates to a medicine for curing osteoporosis and the preparing method thereof. And osteoporosis is one of the frequently seen and occuring diseases in clinical practice, and the old folks frequently suffer from osteoporosis. But the existing variouis medicinal preparations have single function and curative effects less than satisfactory. The invention is composed of Epimedium Herb, Himalayan Teasel Root, Danshen, Common Anemarrhena Rhizome, Malaytea Scurfpea Fruit, and Rehmannia Root according to Chinese medicinal theory, extracts their creams and fully plays the role in tonifying kidney and strengthening bones, and promoting the blood circulation and stopping pain. And its single use on trial in the clinic shows that it has remarkable curative effect and no bad reaction occurs after long-term taken, avoiding bad reaction of combined use of plural medicines and bad interaction between medicines.

Description

1. Technical field: [0001] The invention relates to a medicine for treating osteoporosis and a preparation method thereof. 2. Technical background: [0002] Osteoporosis is a clinical common disease, one of frequently-occurring diseases. It was not until the past 15 years that people gradually paid attention to it. This disease is more common in the elderly. According to reports, there are about 200 million people suffering from osteoporosis in the world at present, and its incidence rate has jumped to the seventh place among various common diseases in the world. In some areas of my country, the incidence rate of osteoporosis in the elderly over 60 years old reaches 59.87%. The international medical community has listed osteoporosis, hypertension, arteriosclerosis, diabetes, and tumors as an important disease of the elderly. [0003] Osteoporosis is a systemic disease with a long course, and the incidence of fractures due to osteoporosis is as high as 9.6%. Fractures not...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K9/28A61P19/10
Inventor 张凌芸
Owner 张凌芸
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