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Pharmaceutical composition for treating atherosclerosis of aorta

A technology of aortic atherosclerosis, composition, applied in the field of medicine

Inactive Publication Date: 2015-03-04
宋婷婷
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Modern medicine believes that AS treatment should change bad living habits, smoking cessation, low-fat diet, weight loss, and proper exercise; the side effects of drugs such as simvastatin and pravastatin and the safety of long-term application need to be further evaluated; interventional therapy still cannot fully Overcoming restenosis and delayed thrombosis after stenting

Method used

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  • Pharmaceutical composition for treating atherosclerosis of aorta
  • Pharmaceutical composition for treating atherosclerosis of aorta

Examples

Experimental program
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Effect test

experiment example

[0020] Experimental example The pharmaceutical composition of the present invention regulates the blood lipid level of the rat aortic atherosclerosis model

[0021] 1 experimental animal

[0022] Select 50 SRF-grade male SD rats, purchased from Beijing Huafukang Biotechnology Co., Ltd. [Certificate No. SCXK (Beijing): 2014-0038], with a body weight of 150g-180g, in the barrier laboratory of the Experimental Animal Center of Shandong Medical University For feeding, the room temperature was kept between 22-26° C., the relative humidity was 50%-60%, the sunlight was irradiated alternately, and food and water were freely ingested. Basic feed and high-fat feed (3% cholesterol, 0.5% sodium cholate, 0.2% propylthiouracil, 5% sugar, 10% lard, and the rest as basic feed) were purchased from Animal Experiment Center of Shandong Medical University.

[0023] 2 Experimental methods

[0024] 2.1 Modeling and grouping

[0025] After being adaptively fed with basic feed for 1 week, the rat...

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PUM

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Abstract

The invention relates to a pharmaceutical composition for treating atherosclerosis of aorta. The pharmaceutical composition is prepared from the following materials in parts by weight: 100-200 parts of elliptic colysis, 50-150 parts of herb of Chinese goldsaxifrage, 100-200 parts of herb of erectspine sanicle, 100-150 parts of red fruit holly, 50-100 parts of platycodon root, 50-100 parts of Chinese osbeckia herb, 50-100 parts of chrysanthemum, 100-150 parts of stem of smoothfruit ventilago, 50-100 parts of aloe, 50-100 parts of oat, 50-100 parts of stem and leaf of assan crotalaria, 50-150 parts of all-grass of lineolate elatostema, 50-100 parts of honeysuckle, 50-150 parts of root or leaf of apricot plum, 50-100 parts of tuber fleeceflower root, 50-150 parts of herb or root of cypress vine, 100-200 parts of seguin chinkapin root, 100-200 parts of herb of prostrate cyathula, 10-100 parts of pilosecalyx acaulescent pegaeophyton, 50-100 parts of belleric terminalia fruit, 50-100 parts of callery pear, 100-200 parts of stephanotis mucronata and 50-100 parts of liquorice root. The raw materials of the pharmaceutical composition interact and are synergetic, and therefore, the pharmaceutical composition is accurate in curative effect, capable of protecting the cardiovascular system, low in cost and free from toxic and side effects.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a pharmaceutical composition for treating aortic atherosclerosis. Background technique [0002] Atherosclerotic diseases are a large class of diseases that endanger human health, especially cardiovascular and cerebrovascular diseases that seriously threaten human life. In the 1960s, the incidence of atherosclerosis (AS) in developed countries such as Europe and the United States increased significantly and became a common epidemic. With the continuous improvement of living standards in my country, changes in dietary structure and lifestyle, and the arrival of social aging, AS has become one of the main causes of death in my country. For a long time, researchers have been deeply exploring the pathogenesis of AS in order to find effective prevention methods. Modern medicine believes that AS treatment should change bad living habits, smoking cessation, low-fat diet, weight loss, and proper...

Claims

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Application Information

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IPC IPC(8): A61K36/886A61K36/896A61P9/10
CPCA61K36/12A61K9/14A61K36/185A61K36/21A61K36/23A61K36/27A61K36/287A61K36/34A61K36/355A61K36/39A61K36/48A61K36/484A61K36/67A61K36/704A61K36/72A61K36/73A61K36/736A61K36/886A61K36/896A61K36/899A61K2300/00
Inventor 宋婷婷
Owner 宋婷婷
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