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Traditional Chinese medicinal preparation for treating infantile exudative otitis media and preparation method thereof

A technology for exudative otitis media and traditional Chinese medicine preparations, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and drug delivery, can solve the problems of easy recurrence, toxic and side effects, and poor curative effects, and achieve exact curative effects and toxic and side effects. small effect

Inactive Publication Date: 2013-12-11
陈爱美
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Most of the medicines for treating otitis media with effusion in the prior art use western medicines such as amoxicillin, erythromycin ethylsuccinate or cefradine to reduce inflammation.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0035] Wherein, when the dosage form of described Chinese medicine preparation is tablet, its preparation method comprises the following steps:

[0036] Step 1: Mix the raw materials and medicinal materials in proportion, add ethanol with an alcohol concentration of 75% to 85% that is 4 to 6 times the mass of the mixture, heat and reflux for 2 to 5 hours, extract, and filter to obtain the first extract , filter the dregs obtained and then add ethanol with an alcohol concentration of 80% to 85% relative to the quality of the dregs 2 to 4 times, heat and reflux for 1 to 2 hours, extract, filter to obtain the second extract, and the first extract Combine with the second extract, concentrate under reduced pressure to remove the ethanol solvent, and dry to obtain a dry paste;

[0037] Step 2: Put the dry paste obtained in the first step into an ultrafine pulverizer for 3 to 5 hours, pulverize and sieve to obtain an ultrafine powder of 300 to 400 mesh;

[0038] Step 3: Add 0.2 to 0...

Embodiment 1

[0041] The tablet that embodiment 1 present invention prepares

[0042] Take 320g of andrographis paniculata, 240g of nasturtium, 120g of Artemisia argyi, 180g of saxifrage, 120g of bile wood, 170g of hibiscus leaf, 70g of mopancao, 90g of ball orchid, 220g of motherwort, 60g of cocklebur, 190g of bellflower and gorgon 130g;

[0043] Its preparation method comprises the following steps:

[0044] Step 1: Mix the above-mentioned raw materials in proportion, add ethanol with an alcohol concentration of 80% that is 5 times the mass of the mixture, heat and reflux for 4 hours, extract, filter to obtain the first extract, and then add the dregs obtained by filtering Ethanol with an alcohol concentration of 85% relative to the quality of the dregs, heated to reflux for 2 hours, extracted, filtered to obtain the second extract, combined with the first extract and the second extract, concentrated under reduced pressure to remove the ethanol solvent, and dried , to obtain dry paste; ...

Embodiment 2

[0047] Embodiment 2 The drops prepared by the present invention

[0048] Take 290g of andrographis paniculata, 210g of nasturtium, 140g of Artemisia argyi, 200g of saxifrage, 150g of bile wood, 160g of hibiscus leaf, 90g of mopancao, 80g of ball orchid, 240g of motherwort, 70g of cocklebur, 160g of bellflower and Gorgon 110g;

[0049] Its preparation method comprises the following steps:

[0050] Soak the above-mentioned raw materials in ethanol with a concentration of 4 times of 85% for 40 hours, then thermally extract at 80°C for 3 times, each time for 1 hour, to obtain an ethanol extract; finally concentrate it to a concentration with a relative density of 1.06 liquid.

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Abstract

The invention discloses a traditional Chinese medicinal preparation for treating infantile exudative otitis media and a preparation method thereof. The preparation comprises the following medicinal raw materials: common andrographis herb, globeflower, artemisia rupestris, saxifraga aculeate, nauclea officinalis pierre ex petard, cottonrose hibiscus leaf, honewort, hoya carnosa, polygonum chinense, xanthium sibiricum, rust-brown crotalaria and gordon euryale seed. The traditional Chinese medicinal preparation has the beneficial effects of clearing heat, removing toxicity, cooling blood, stopping bleeding, activating blood circulation, inducing resuscitation, reducing swelling and relieving pain on the basis of the traditional Chinese medical theory, has definite curative effect on infantile exudative otitis media and hardly causes toxic and side effects.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine preparation for treating children with effusion otitis media and a preparation method thereof. Background technique [0002] Otitis media with effusion is a non-suppurative inflammation of the middle ear characterized by tympanic effusion and hearing loss. Children have a higher incidence rate and are one of the common causes of hearing loss in children. According to foreign statistics, more than 50% of infants suffer from this disease, and the high incidence age of children is 5 years old. In my country, about 90% of preschool children have suffered from otitis media with effusion, and most of them are between 6 months and 4 years old. [0003] The etiology of effusion otitis media is complex, mainly including eustachian tube dysfunction, infection factors and immune response. The high morbid...

Claims

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Application Information

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IPC IPC(8): A61K36/74A61K9/08A61P27/16
Inventor 陈爱美郑霞薛灵敏陈静赵震陈晓阳
Owner 陈爱美
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