14 results about "Mahonia" patented technology

The invention discloses application of berberine or berberine hydrochloride in preparation of drugs for resisting HPV infection related diseases. Preferably, the berberine is an extract of natural plants such as coptis chinensis, golden cypress, berberis poiretii schneid or Chinese mahonia. According to the application, the new application of the berberine or the hydrochloride thereof in the aspect of resisting the HPV virus is expanded, and the berberine or the hydrochloride thereof is used for preparing the preparation for resisting the HPV infection, so that diseases related to the HPV infection can be prevented or treated, and the virus is promoted to become negative. As a natural plant extract, berberine is high in safety and not easy to generate drug resistance, and has important clinical significance when being used for preparing Chinese patent medicine products for resisting HPV infection.

The present application relates to the germination technology field of Tibetan Mahonia, especially to a method for improving the germination of Tibetan Mahonia, comprising the following steps: step S1, selecting seeds, which comprises fruit air-drying, shell screening and paper bag dry storage; step S2, cultivating seeds, which comprises culture dish setting, seed scattering and constant temperature heating; step S3, germination transplanting, which comprises nutrient soil preparation, moving to a culture box, appearance observation and re-transferring; step S4, later maintenance, which comprises climate preference and disease control; when the temperature of the constant temperature box is 25-30 DEG C, the seed germination rate reaches more than 84%, so the temperature of the constant temperature box is adjusted to 25-30 DEG C, so as to improve the seed germination rate; when the loess and peat soil ratio is 1:4, the survival rate of seedlings is as high as 90%, while when the loess and peat soil ratio is not 1:4, the survival rate of seedlings is less than 90%, so the loess and peat soil ratio is adjusted to 1:4, so as to improve the survival rate of seedlings.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a composition for treating yin deficiency and phlegm stasis syndromes as well as a preparation method and application thereof. The composition is prepared from the following medicinal raw materials: rhizoma bletillae, thunberg fritillary bulb, platycodon grandiflorum, radix stemonae, lily, bryozoatum, radix asteris, pseudo-ginseng, Chinese mahonia stem and liquorice. The preparation method comprises the following steps: (1) adding alcohol into rhizoma bletillae, pseudo-ginseng, Chinese mahonia stem and liquorice, and performing reflux extraction to obtain an alcohol extract and decoction dregs; (2) mixing platycodon grandiflorum, thunberg fritillary bulb, radix stemonae, lily, bryozoatum and radix asteris, adding water, decocting, performing microwave treatment, and filtering to obtain an aqueous extract; (3) mixing the medicine residue and the water extract, performing enzymolysis, decocting, and centrifuging to obtain supernate; and (4) mixing the alcohol extract and the supernate, concentrating and drying to obtain the composition. A specific preparation method is adopted, the effects of active ingredients in the traditional Chinese medicine components can be fully exerted, and the treatment score evaluation on the yin deficiency and phlegm stasis syndrome is remarkably improved.

The invention relates to the field of traditional Chinese medicines, in particular to novel application of a Sweeping Tianhu lung-clearing and cough-relieving composition in treatment of chronic obstructive pulmonary disease. Animal experiment studies show that the Sweetio lung-clearing and cough-relieving composition can significantly improve the lung function of COPD mice and inhibit bronchial abnormal remodeling. The action mechanism of the composition is related to inhibition of lung tissue cell apoptosis, alleviation of inflammatory cell infiltration and improvement of abnormal remodeling of bronchus, which indicates that the Sweeping Litu composition for clearing away lung-heat and relieving cough has obvious pharmacological activity of resisting COPD (chronic obstructive pulmonary disease).

The invention relates to the field of traditional Chinese medicine preparations and the technical field of medicine analysis, in particular to a traditional Chinese medicine composition for treating liver cancer and intestinal cancer and a preparation method and a detection method thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 200 to 300 parts of herba taraxaci, 200 to 300 parts of herba rabdosiae, 250 to 350 parts of ganoderma lucidum spore powder, 50 to 150 parts of solanum lyratum, 250 to 350 parts of centipede, 200 to 300 parts of radix scutellariae, 250 to 350 parts of oldenlandia diffusa, 250 to 350 parts of herba andrographitis, 400 to 500 parts of phellinus igniarius, 250 to 350 parts of radix tetrastigme, 50 to 200 parts of Chinese mahonia and 100 to 250 parts of agkistrodon halys. The traditional Chinese medicine composition has the effects of clearing away heat and toxic materials, removing blood stasis and phlegm, eliminating sores and removing stasis and is used for treating liver cancer and intestinal cancer.

The invention belongs to the field of modernization of traditional Chinese medicines, and particularly relates to a preparation method and a detection method of a Chinese mahonia leaf extract. The preparation method of the Chinese mahonia leaf extract comprises the following steps: taking Chinese mahonia leaf decoction pieces, adding water, decocting, and filtering to obtain filtrate, thereby obtaining the Chinese mahonia leaf extract. The Chinese mahonia leaf extract obtained by the preparation method is high in extract yield and high in transfer rate of index components. The invention also provides a detection method and a thin-layer identification method for the total content and the total transfer rate of the index components in the Chinese mahonia leaf extract, and the content of jatrorrhizine hydrochloride, palmatine hydrochloride and berberine hydrochloride is determined through a thin-layer chromatography identification map of the Chinese mahonia leaf extract. The quality of the Chinese mahonia leaf extract can be evaluated more effectively, and meanwhile, a scientific and reasonable basis is provided for formulating process standards and quality standards of the Chinese mahonia leaf extract.

The invention provides a traditional Chinese medicine preparation for preventing and treating poultry candida albicans and a preparation method thereof, and relates to the technical field of traditional Chinese veterinary medicine pharmacy. The traditional Chinese medicine preparation disclosed by the invention is prepared by fermenting traditional Chinese medicine raw materials consisting of green ox gall, Chinese mahonia stem, grifola frondosa, bighead atractylodes rhizome, jasminum grandiflorum, oriental wormwood, radix polygonati officinalis, radix scrophulariae, soapberry, spina gleditsiae, nostoc sphaeroids kutz and juncus roemerianus with probiotics. After fermentation of the probiotics, active ingredients of the traditional Chinese medicines are better released, body absorption is facilitated, bioavailability is improved, body intestinal health can be maintained to a certain extent due to addition of the probiotics, the body can recover to be normal from a disease state, and the cure rate of the poultry candida albicans disease is remarkably improved. The traditional Chinese medicine preparation provided by the invention has a relatively strong in-vitro inhibition effect on candida albicans, and also has a relatively high effective treatment rate on meat pigeons infected with candida albicans.

The invention belongs to the technical field of functional drinks, and particularly relates to a probiotic fermented traditional Chinese medicine composition for treating diabetes and a preparation method thereof. Based on the diabetes pathogenesis of traditional Chinese medicine, modern pharmacological research is combined to optimize compatibility. Compatibility is performed according to the monarch, minister, assistant and guide composition principle of the traditional Chinese medicine prescription. The traditional Chinese medicine composition is prepared by taking astragalus membranaceus as a monarch drug, taking Chinese yam, medlar, fructus broussonetiae, flatstem milkvetch seed and Chinese mahonia stem as ministerial drugs, taking poria cocos, salvia miltiorrhiza, gynostemma pentaphylla and burdock as adjuvant drugs and taking kudzu vine root, corydalis amabilis, dark plum and fermented soybean as conductant drugs through scientific compatibility and a preparation process, not only can directly act on the hyperglycemia core, but also takes pathology and symptom and drug property balance into account, and has a remarkable curative effect. The effects of reducing blood sugar, protecting pancreas, preventing complications and regulating intestinal tracts are realized.

The invention relates to a traditional Chinese medicine preparation for treating Meniere's syndrome, and belongs to the technical field of traditional Chinese medicine preparation. The traditional Chinese medicine preparation for treating the meniere syndrome is prepared from turtle shells, rhizoma anemarrhenae, concha haliotidis, oviductus ranae, flatstem milkvetch seeds, Chinese mahonia stems, radix pseudostellariae, fried white hyacinth beans, mistletoe, exocarpium citri grandis, trichosanthes kirilowii maxim, calyx seu fructus physalis, bombyx batryticatus, mint and liquorice. The traditional Chinese medicine preparation has the effects of enriching yin, nourishing kidney, calming liver, suppressing yang, tonifying spleen, reducing phlegm and clearing head and eyes. The traditional Chinese medicine preparation has remarkable advantages in the aspect of improving or relieving clinical symptoms of the meniere syndrome, the total effective rate of treatment can be remarkably increased, and meanwhile the recurrence rate can be remarkably reduced.

The present application relates to a kind of SSR molecular marker primer set of Mahonia, and its application, the forward primer sequence of the SSR molecular marker primer set includes the sequence as shown in any one of SEQ ID NO:1-7 or as shown in any one of SEQ ID NO:1-7;The reverse primer sequence of the SSR molecular marker primer set includes the sequence as shown in any one of SEQ ID NO:8-14 or as shown in any one of SEQ ID NO:8-14, the SSR molecular marker primer set of the present application is accurately identified long column Mahonia, and it guarantees the authenticity of base original variety for its relevant quality standard research.

The present application belongs to the technical field of traditional Chinese medicine modernization, and particularly relates to a fingerprint spectrum detection method of Mahonia leaf, and an identification and extraction method thereof. The fingerprint spectrum detection method of Mahonia leaf comprises the following steps: (1) preparation of a reference solution; (2) preparation of a sample solution: taking a Mahonia leaf sample and adding an extraction solvent B for extraction; (3) performing ultra-high performance liquid chromatography analysis on the reference solution and the sample solution; and (4) establishing a fingerprint spectrum of the Mahonia leaf medicinal material. The fingerprint spectrum detection method of Mahonia leaf can identify Mahonia leaf of different origins, and screen common characteristic peaks and / or potential differential components of Mahonia leaf of different origins. In addition, the extraction method can extract index components of Mahonia leaf through column layer analysis. The chemical fingerprint spectrum method of the present application is stable and reliable, can significantly distinguish Mahonia leaf of different origins, and can provide a reference for quality control, evaluation and origin identification of Mahonia leaf, and has important significance for ensuring clinical efficacy.

The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for treating early diabetic nephropathy and a preparation method and application thereof. The composition is prepared from 15-45 g of raw radix astragali, 10-15 g of radix pseudostellariae, 9-15 g of radix salviae miltiorrhizae, 9-15 g of radix paeoniae rubra, 10-15 g of radix achyranthis bidentatae, 3-6 g of earthworms, 10-15 g of centella asiatica, 9-12 g of salvia chinensis, 15-30 g of gordon euryale seeds, 9-12 g of fructus broussonetiae, 9-12 g of Chinese holly leaves, 9-12 g of winged euonymus twigs, 10-15 g of poria cocos, 9-12 g of pericarpium citri reticulatae and 15-30 g of corn stigma (decocted in a wrapped mode). The traditional Chinese medicine has the beneficial effects of invigorating spleen and tonifying kidney, reinforcing qi and nourishing yin, promoting blood circulation to remove meridian obstruction, and dispersing blood stasis and discharging turbidity. The traditional Chinese medicine composition is used for treating early diabetic nephropathy caused by deficiency of both qi and yin, insufficiency of spleen and kidney and internal resistance of blood stasis and turbid toxin, and has the following syndromes: turbid urine or foam urine, soreness and weakness of waist and knees, lassitude and weakness, dry mouth and throat, slight edema of limbs (for lower limbs), less lush complexion, or numbness of limbs, light dark or dark red tongue, or stasis spots and ecchymosis, thin white or slightly greasy fur, and the like. The pulse is fine, astringent or fine.

The present application belongs to the technical field of tissue culture, and particularly relates to a culture medium and a culture method for culturing leaf callus of Leucadendron. The present application provides a culture medium for culturing leaf callus of Leucadendron, wherein the culture medium comprises an induction culture medium and a proliferation culture medium; 6-BA in the induction culture medium and the proliferation culture medium promotes cell division, 2,4-D induces the generation of callus and promotes the growth of callus, and NAA can promote the generation and proliferation of callus; under the specific 6-BA, 2,4-D, NAA, suitable sucrose concentration and specific basic culture medium, the hormone balance of Leucadendron in vitro leaf can be maintained, and the growth and proliferation of callus are promoted. The present application provides a method for culturing callus of Leucadendron by taking Leucadendron leaf as an explant, inducing leaf dedifferentiation to form callus and proliferating culture, wherein the proliferation coefficient of callus is high, and the texture is good.

The invention discloses a composition with a whitening effect and application of the composition in cosmetics, and belongs to the technical field of cosmetics, the composition with the whitening effect is prepared from 1-3 parts of Chinese holly leaf extract, 1-2 parts of herba cepbalanoplosis segeti extract, 0.5-1.5 parts of Chinese mahonia leaf extract and 0.1-1 part of composite whitening agent; wherein the composite whitening agent is prepared from tranexamic acid, 4-butylresorcinol and nonapeptide-1 according to the mass ratio of 1 to (0.1 to 0.6) to (0.2 to 0.4). The obtained composition with the whitening effect has a remarkable effect of inhibiting tyrosinase, and cosmetics obtained by applying the composition to the cosmetics can remarkably inhibit the skin melanin content and are mild and non-irritating.