The invention provides an acupoint application traditional Chinese medicine composition for yang-qi deficiency and vein stasis syndrome and a preparation method of the acupoint application traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from, in parts by weight, 12 parts of semen brassicae, 12 parts of rhizoma corydalis, 10 parts of euphorbia kansui, 3 parts of herba asari, 6 parts of fructus evodiae, 6 parts of pepper, 6 parts of clove, 12 parts of rhizoma cyperi, 6 parts of pepper, 12 parts of dried ginger, 15 parts of rhizoma typhonii slices, 12 parts of rhizoma atractylodis, 15 parts of cortex eucommiae, 15 parts of fructus alpiniae oxyphyllae, 10 parts of radix angelicae sinensis, 30 parts of radix astragali, 15 parts of radix dipsaci, 12 parts of herba cynomorii, 12 parts of cortex phellodendri, 15 parts of radix angelicae pubescentis, 12 parts of herba taxilli, 15 parts of glossy privet fruits and 12 parts of herba ecliptae. The traditional Chinese medicine acupoint application is prepared by adding the traditional Chinese medicines capable of invigorating yang, opening the kidney and warming and tonifying the spleen and kidney on the basis of tonifying qi, activating blood, warming and activating meridians and promoting qi circulation to relieve pain under the guidance of the Xuefu theory, and a good curative effect is achieved through long-term clinical practice improvement.