The invention discloses a drug for treating the Hashimoto disease and a preparing method thereof. The drug is prepared from aeschynanthus acuminatus, gynostemma pentaphyllum, spina date seeds, folium isatidis, lycopodium obscurum, petrea volubilis, lotus seeds, arillus longan, acanthopanax, fragrant sarcococca herbs, cynanchum wilfordii, meadowrue roots and rhizomes, rhizoma cimicifugae, poria with hostwood, gaultheria yunnanensis, cacumen biotae, fructus tritici levis, asarum, ficus pandurata hance, Chinese honey locust, Chinese dates, jasminum laurifolium, lucid ganoderma, pericarpium trichosanthis, cordia dichotoma and polygala tenuifolia. The drug has the beneficial effects of being capable of promoting blood circulation to remove meridian obstruction, removing heat from the liver, invigorating spleen to remove phlem, tranquilizing by nourishing the heart, and nourishing yin to lessen fire, capable of becoming effective quickly, high in efficiency, definite in curative effect, short in treatment course, free of toxic or side effect, low in price, and capable of enhancing the immunity of the body and treating the Hashimoto disease.