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Drug for treating Hashimoto disease and preparing method thereof

A technology for Hashimoto's disease and medicine is applied in the field of medicine for treating Hashimoto's disease and its preparation, which can solve the problems of dependence and side effects, unfavorable treatment, and cure the symptoms but not the root cause, and achieves definite curative effect, enhanced immunity, Effects without toxic side effects

Inactive Publication Date: 2016-03-23
王玉洁
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Current western medicine treatment: treating the symptoms but not the disease, is unfavorable for treatment, and commonly used has dependence and side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0061] When the dosage form of the drug is granules, the preparation method includes the following steps:

[0062] In the first step, the raw materials are mixed according to the proportion, and ethanol with an alcohol concentration of 85%-95% is added 4-8 times of the mixture, heated to boiling and refluxed for 3-5 hours, filtered, and the percolation method is used Slowly permeate at a rate of 1-2ml per minute, collect the percolate, and then concentrate it under reduced pressure under a vacuum of 0.06-0.09Mpa to a paste with a relative density of 1.04-1.10 at 50-60°C, spray dry, and spray The inlet air temperature of the dryer is 160-175°C and the outlet air temperature is 80-85°C, and then crushed into powder to make dry paste powder;

[0063] In the second step, 0.2-0.4 times of sucrose powder and 0.1-0.2 times of dextrin relative to the mass of the dry paste powder are added to the obtained dry paste powder to form granules, which are dried at 40-50° C. to obtain granules.

[...

Embodiment 1

[0073] Example 1 Granules

[0074] The preparation process of the granule of the present invention is: take Gynostemma pentaphyllum 160g, jujube seed 280g, large green leaf 200g, jade cypress 140g, lotus seed 250g, longan meat 300g, acanthopanax 160g, stomach mate 120g, horsetail 240g, cohosh 120g, and fu Shen 300g, Platycladus orientalis 110g, Floating wheat 330g, Asarum 250g, Ficus lutea 320g, Chinese honey locust 20g, Jujube 350g, Ganoderma 220g, Trichosanthes 180g, Ragwood 300g and Polygala 250g;

[0075] In the first step, the raw materials are mixed according to the stated proportions, and ethanol with a concentration of 90% alcohol is added 7 times the mixture, heated to boiling and refluxed for 4 hours, filtered, and diafiltration is used at a rate of 2ml per minute. Slowly permeate, collect the percolate, and then concentrate it under reduced pressure under a vacuum of 0.07Mpa to a paste with a relative density of 1.07 at 55°C, spray drying, the inlet air temperature of th...

Embodiment 2

[0077] Example 2 Capsules

[0078] The preparation process of the capsule of the present invention is: take Gynostemma pentaphyllum 180g, wild jujube seed 250g, large green leaf 160g, jade cypress 300g, lotus seed 180g, longan meat 320g, acanthopanax 120g, stomach mate 100g, horsetail line 220g, cohosh 140g, and fu Shen 250g, Platycladus orientalis leaf 100g, floating wheat 330g, Asarum 260g, Ficus lutea 330g, Chinese honey locust 20g, Jujube 350g, Ganoderma 220g, Trichosanthes 150g, Ragwood 300g and Polygala 170g

[0079] In the first step, the raw medicinal materials are mixed in proportions, and ethanol with an alcohol concentration of 90% relative to the mass of the mixture is added, heated to reflux for 2 hours, extracted, filtered to obtain the first extract; the dregs obtained by filtration are added again The ethanol with an alcohol concentration of 95%, which is 1.5 times the mass of the drug residue, is heated and refluxed for 2 hours, extracted and filtered to obtain a s...

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PUM

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Abstract

The invention discloses a drug for treating the Hashimoto disease and a preparing method thereof. The drug is prepared from aeschynanthus acuminatus, gynostemma pentaphyllum, spina date seeds, folium isatidis, lycopodium obscurum, petrea volubilis, lotus seeds, arillus longan, acanthopanax, fragrant sarcococca herbs, cynanchum wilfordii, meadowrue roots and rhizomes, rhizoma cimicifugae, poria with hostwood, gaultheria yunnanensis, cacumen biotae, fructus tritici levis, asarum, ficus pandurata hance, Chinese honey locust, Chinese dates, jasminum laurifolium, lucid ganoderma, pericarpium trichosanthis, cordia dichotoma and polygala tenuifolia. The drug has the beneficial effects of being capable of promoting blood circulation to remove meridian obstruction, removing heat from the liver, invigorating spleen to remove phlem, tranquilizing by nourishing the heart, and nourishing yin to lessen fire, capable of becoming effective quickly, high in efficiency, definite in curative effect, short in treatment course, free of toxic or side effect, low in price, and capable of enhancing the immunity of the body and treating the Hashimoto disease.

Description

Technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating Hashimoto's disease and a preparation method thereof. Background technique [0002] Hashimoto's disease is the abbreviation of chronic lymphocytic thyroiditis and belongs to the category of "Gall Disease" in Chinese medicine. It is an autoimmune disease characterized by a large number of lymphocytes infiltration in thyroid tissue and a large number of anti-thyroid antibodies in the serum. Hashimoto's disease is common in middle-aged women. Many patients have no obvious clinical symptoms in the early stage of the disease. Most patients are treated with diffuse thyroid enlargement. They may have a tight neck, manifested as goiter, slow onset, and often inadvertently. It was found that the volume is about 2-3 times that of normal thyroid gland, the surface is smooth, the texture is tough and elastic like rubber, obvious nodules are rare, ther...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P29/00A61P37/02
CPCA61K9/1652A61K9/2059A61K9/4858A61K36/074A61K36/076A61K36/11A61K36/14A61K36/185A61K36/195A61K36/254A61K36/268A61K36/27A61K36/30A61K36/315A61K36/424A61K36/428A61K36/45A61K36/483A61K36/60A61K36/62A61K36/69A61K36/704A61K36/71A61K36/725A61K36/77A61K36/855A61K36/899A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 王玉洁赵媛媛
Owner 王玉洁
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