103 results about "Goiter" patented technology

New thyroid receptor ligands are provided which have general formula (I) in which: n is an integer from 0 to 4; R1 is halogen, trifluoromethyl, or alkyl of 1 to 6 carbons or cycloalkyl of 3 to 7 carbons; R2 and R3 are the same or different and are hydrogen, halogen, alkyl of 1 to 4 carbons or cycloalkyl of 3 to 5 carbons, at least one of R2 and R3 being other than hydrogen; R4 is a carboxylic acid amide (CONR′R″) or an acylsulphonamide (CONHSO2R′) derivative, or a pharmaceutically acceptable salt thereof, and all stereoisomers thereof; or when n is equal to or greater than one, R4 may be a heteroaromatic moiety which may be substituted or unsubstituted, or an amine (NR′R″). R5 is hydrogen or an acyl (such as acetyl or benzoyl) or other group capable of bioconversion to generate the free phenol structure (wherein R5=H). In addition, a method is provided for preventing, inhibiting or treating a disease associated with metabolism dysfunction or which is dependent upon the expression of a T3 regulated gene, wherein a compound as described above is administered in a therapeutically effective amount. Examples of such diseases associated with metabolism dysfunction or are dependent upon the expression of a T3 regulated gene include obesity, hypercholesterolemia, atherosclerosis, cardiac arrhythmias, depression, osteoporosis, hypothyroidism, goiter, thyroid cancer as well as glaucoma, congestive heart failure and skin disorders.

A traditional Chinese medicine for curing subacute thyroiditis belongs to a traditional Chinese medicine for curing swollen masses goiter. The components contain: 15g of Chinese thorowax root, 15g of baical skullcap root, 15g of pinellia tuber, 15g of Chinese angelica,15g of turmeric root tuber, 15g of zedoray rhizome, 15g of turtle shell, 15g of radix semiaquilegiae, 15g of weeping forsythia capsule, 15g of seaweed, 15g of lucid ganoderma, 15g of tree peony bark, 20g of common selfheal fruit-spike, 20g of bulbus fritillariae thunbergii, 20g of figwort root, 20g of spreading hedyotis herb, 20g of roasted himalayan teasel root, 20g of prepared flowery knotweed root, 30g of milkvetch root, 30g of heterophylly falsesatarwort, 30g of oyster and 10g of dried leech; the invention has the auxiliary prescriptions that: for severe heat, the common selfheal fruit-spike is added to 30g of, and 10g of common anemarrhena rhizome is added; for severe pain, 10g of platycodon root, 10g of blackberrylily rhizome and 10g of paris root are added. The compatibility of the traditional Chinese medicine is simple; the medicine used in the prescription is fully natural herbal medicine, which is easy to collect and use; the preparation method is simple; the effects for taking and curing are good; the cost of the medicine is low, and the medicine is in particular suitable for the people living in remote villages far from towns; the cost is low for curing the people suffering from subacute thyroiditis, which solves the problem that the local area lacks medical conditions to cure the disease because of low household income and poor living condition.

The invention belongs to the field of externally-used traditional Chinese medicines, in particular to an externally-used hot compress mud plaster for treating pains of a human body and a preparation method thereof. The externally-used hot compress plaster comprises the following raw materials: 10-15% of natural jade mud powder, 3-5% of tourmaline micro powder, 3-5% of far infrared ceramic micro powder, 15-25% of Chinese medicinal herb, 10-20% of mud plaster matrix, 25-35% of beeswax and 5-15% of red lead. The externally-used hot compress mud plaster is used for acupuncture points of the human body. The mud plaster is heated to melt; after about 10-15 minutes, the cooling melted mud plaster is sticked to a pain area after being cleaned, so as to activate the vigor of skins, and expel toxins of the skins. The hot compress mud plaster has the advantages of heat absorption and heat preservation, even heat dissipation, consistent temperature, can get through the meridians, dispel the wind and remove the cold, activate blood circulation to dissipate blood stasis, eliminate goiter and tumour, thoroughly remove the pain, treat headache, toothache, prosopalgia, sore-throat, chest and hypochondriac pain, epigastric pain, bellyache, gout, backleg pain and cerv shoulder pain, herniated disk, ischialgia, rheumatalgia, and spinal pain; and the plaster in the invention is convenient to stick to the different parts of the human body, does not harden and flow, solidifies after taking away from the human body, and can be reused by repeated heating.

The invention discloses a traditional Chinese medicine composition for treating subacute thyroiditis. The composition is a preparation prepared from the following raw materials by weight: 15-30 parts of hedyotis diffusa, 9-15 parts of honeysuckle, 15-30 parts of dandelion, 15-30 parts of Chinese violet, 9-15 parts of root of common peony, 9-15 parts of radix scrophulariae, 9-15 parts of peach kernel, 9-15 parts of baked turtle shell and 15-30 parts of sweet wormwood. According to clinical study on the treatment of subacute thyroiditis, the traditional Chinese medicine composition provided by the invention has total effective rate of 93.34%, which is significantly better than 73.33% of a prednisone group, and can effectively reduce erythrocyte sedimentation rate and CRP of subacute thyroiditis patients, and effectively improve clinical symptoms of the patients; although the cooling time, improvement time of neck pain and regression time of neck tenderness are longer than those of the prednisone group, the goiter or nodule disappearance time shows no obvious difference from those of the prednisone group; relapse rate after drug withdrawal is 3.33%, which is significantly lower than 20% of the prednisone group; and the composition has little adverse reaction, which is significantly lower than that of the prednisone group. The invention also discloses a preparation method of the traditional Chinese medicine composition granules.

A traditional Chinese medicine for curing hashimoto's thyroiditis belongs to a traditional Chinese medicine for curing swollen masses goiter. The components contain: 9g of Chinese thorowax root, 9g of turmeric root tuber, 9g of nutgrass galingale rhizome, 9g of Baical Skullcap Root, 12g of Akebia Fruit, 12g of Bidens bipinnata L., 12g of Tuckahoe, 12g of Peach Seed, 30g of Milkvetch Root, 30g of Isatis Root, 20g of dried date and 6g of sward. The substances in the prescription are made from natural traditional Chinese medicine plus traditional preparing methods. The materials are easy to collect, the prescription and the preparation methods are simple, and the cost of medicine preparation is low. The compatibility of the traditional Chinese medicine is simple; the medicine used in the prescription is fully natural herbal medicine, which is easy to collect and use; the preparation method is simple; the effects for taking and curing are good; the cost of the medicine is low, and the medicine is in particular suitable for the people living in remote villages far from towns; the cost is low for curing the people suffering from hashimoto's thyroiditis, which solves the problem that the local area lacks medical conditions to cure the disease because of low household income and poor living condition.

The invention relates to the field of pharmaceutical chemistry, in particular to medical use of 34 compounds and medicinal composition containing the compounds, particularly use as Polo like kinase 1 inhibitor. Diseases associated with the Polo like kinase 1 inhibitor include melanoma, liver cancer, kidney cancer, acute leukemia, non-small-cell lung cancer, prostatic cancer, cancerous goiter, skin cancer, colorectal cancer, pancreatic cancer, ovarian cancer, breast cancer, myelodysplastic syndromes, esophageal cancer, gastrointestinal tract cancers or mesothelioma.

The invention discloses a medicament for treating hyperthyroidism and a preparation method thereof. The medicament for treating hyperthyroidism of the invention is mainly prepared from the following raw material in part by weight: 300 to 500 parts of common selfheal fruit-spike, 200 to 400 parts of figwort root, and 200 to 300 parts of airpotato yam rhizome. The raw materials also include 200 to 400 parts of rhizoma bolbostemmae and / or 500 to 700 parts of raw oyster. Preferably, the medicament is prepared from the following raw materials in part by weight: 400 parts of common selfheal fruit-spike, 300 parts of figwort root, 240 parts of airpotato yam rhizome, 300 parts of rhizoma bolbostemmae and 600 parts of raw oyster. The medicament can be formed into any pharmaceutical formulation. The formulation is capsules. The medicament of the invention has the functions of nourishing yin, suppressing yang, detoxifying, eliminating goiter, reducing phlegm and resolving masses. The medicament can treat hyperthyroidism and is agreeable with patients incapable of bearing western medicaments.

The invention discloses a traditional Chinese medicine preparation used for treating hyperthyroidism. The hyperthyroidism belongs to the categories of goiter and palpitation in the traditional Chinese medicine science. Basic pathogenesis comprises stagnation of liver qi, fire transformation owning to depression, qi and fluid loss, phlegmostagnant blood stasis, overstrain and deficiency of qi and yin due to impairment spleen and qi consumption owning to liver fire. Thus, traditional Chinese medicines abrus herb, fiveleaf akebia fruit, persian veronica, selenitum, dried rehamnnia root, asparagus fern, ophiopogon latifolius, cortex albiziae, tree falsespiraea bark, cornu procaprae gutturosae, concha ostreae, airpotato yam rhizome and clausena lansium kernel are selected and prepared into an orally taken decoction by a medicine preparation room of a hospital (described in the specification), clinical test shows that the total effective rate is 97.2%, and indicators of each treatment group are respectively obviously improved.

The invention discloses a traditional Chinese medicine composition for treating qi goiter, which is prepared from the following active pharmaceutical ingredients: 15 parts of radix bupleuri, 15 parts of lychee seed, 15 parts of Aspongopus, 15 parts of Jasminum grandiflorum, 12 parts of radix curcumae, 50 parts of laminaria, 50 parts of seaweed, 20 parts of mother-of-pearl, 20 parts of tortoise plastron, 20 parts of testa trionidis, 20 parts of dragon bone, 20 parts of oyster, 20 parts of swimming bladder gelatin, 20 parts of wolfberry fruit, 18 parts of radix paeoniae alba, 18 parts of glossy privet fruit, 20 parts of radix asparagi, 50 parts of raw hawthorn, 15 parts of costus root, 10 parts of Mangnolia officinalis and 12 parts of licorice root. The traditional Chinese medicine composition for treating qi goiter disclosed by the invention has the advantages of no toxic or side effect, obvious curative effect, wide medicine sources and low price; and the effective rate for treating qi goiter is 96%, and the cure rate is 88%.

The invention discloses a saliva proteome decision-making tree diagnosis model for screening thyroid cancer, and a construction method of the tree. The construction method comprises the following steps: collecting the saliva of patients with a thyroid cancer, patients with benign nodular goiter, and healthy people, standing, carrying out centrifugal treatment and the like, and combining with an NP20 chip; detecting the chip by adopting a PBS type-II protein chip reader, and automatically acquiring data by adopting Proteinchip Software 3.2.1 analysis software; carrying out bioinformatics statistic analysis; and building the diagnosis model by comparing saliva differential protein between a thyroid cancer group and a healthy control group, which is composed of four protein peaks with mass-to-charge ratios (M / Z) of 3491.10, 3642.28, 4315.10 and 7424.63 in a saliva protein mass spectrum, and by comparing saliva differential protein between a thyroid cancer group and a benign nodular goiter group, which is composed of four protein peaks with mass-to-charge ratios (M / Z) of 2587.38, 3346.06, 3584.20 and 8054.57 in the saliva protein mass spectrum. The construction method disclosed by the invention is simple, non-invasive, high in operability, high in specificity and high in sensibility; the diagnosis model provides a specific marker for early diagnosis and qualitative diagnosis levels for the thyroid cancer.

The present invention relates to a kind of Chinese medicine preparation, named Jiazhuangling, for treating hyperthyroidism, thyroid tumor, thyroid cyst and endemic goiter. The Chinese medicine preparation has obvious curative effect, short treating period and less recurrence.

A traditional Chinese medicine for remedying the gall belongs to the traditional Chinese medicine for remedying the goiter. The components contain: 15g of bupleurum roots, 12g of orange fruits, 12g of tangerine peels, 12g of rhizome of nutgrass galingale, 9g of Szechwan lovage rhizome, 9g of peony roots and 6g of liquorice. The dosage materials in the prescription are all made from natural traditional Chinese herbal medicines by the traditional processing method. The materials can be easily gotten; the prescription and the preparation method are simple; the expense for preparing the medicine is low. The compatibility of the traditional Chinese herbal medicines is simple; the medicines used in the medicine prescription are all natural herbal medicines which can be conveniently gotten and used; the manufacturing method is simple; the curative effect after being taken is good; the medicine price is cheap, and the medicine is especially fit for people who live at the remote small villages away from villages and towns to use. The treatment expense for the patient with the disease of the gall is low, which solves the treatment problem which is caused by low family income, poor living and lack of local medical treatment condition.

The invention discloses a medicine for treating goiter. The medicine is prepared with Chinese medicine raw materials including, by weight, 50 parts of astragalus, 25 parts of hairy asiabell, 15 parts of bighead atractylodes rhizome, 25 parts of poria, 15 parts of white peony root, 15 parts of selfheal, 15 parts of seaweed, 15 parts of kelp, 50 parts of oysters, 25 parts of magnetite and 50 parts of red dates. The medicine has the functions of softening hardness to dissipate stagnation, promoting blood circulation to remove blood stasis and the like, thoroughly treats a patient suffering the goiter, has a fine treatment effect, has no toxic and side effects, and is short in treatment cycle, low in cost and convenient to popularize and apply. Besides, the patient rapidly recovers, and the goiter does not easily recur.

A Chinese medicine for treating thyroidism is prepared from 11 Chinese-medicinal materials including black plum, white peony root, capejasmine fruit, mulberry leaf, etc. Its preparing process is also disclosed.

A Chinese traditional medicine for curing goiter belongs to the Chinese traditional medicine for curing goitre. The ingredients of the medicine (with weights) are: alga 6g, kelp 6g, air potato yam rhizome 6g, frankincense 6g and borneol 3g. The medicines used in the prescription are all natural herbs and the Chinese traditional medicine is processed with traditional method; the fetching of material is convenient and the prescription and manufacture method are simple; the expense for manufacturing the medicine is low. The composition of the Chinese herbal medicine is simple and the medicines used in the prescription are all natural ones and the fetching and use are convenient; the manufacture method is simple and the effect is excellent; the price is low; in this way, the herbal medicine is especially fit for people living in remote villages far away from counties and towns; the curing expense for patients with the disease of goitre is low which solves the problem that the household income is low and the life is poor and the medical conditions is deficient locally.

The invention relates to a drug for treating nodular goiter. The drug is prepared from the following traditional Chinese medicine raw materials by weight: 1-5g of herb of white clover, 2-5g of stem of sargentgloryvine, 3-7g of oval kumquat root, 2-5g of root of kerr treebine, 3-10g of Indian melothria root, 5-8g of sinkiang fritillary bulb, 1-5g of cynanchum mooreanum, 10-20g of sweet potatoes, 5-10g of allium macrostemon, 3-5g of resina populi, 2-6g of ulva, 2-5g of stellaria aquatica and 1-3g of kirilow rhodiola rhizome and root. The drug disclosed by the invention is prepared from pure traditional Chinese medicine raw materials, has the effects of promoting qi and clearing liver fire, reducing phlegm and resolving masses, warming middle warmer and supporting yang, softening hard mass and removing cervical mass, nourishing yin and promoting blood flow, realizes determination of etiologic factors based on visceral pattern identification and precisely determines pathogenesis, is exact and remarkable in curative effect of treating nodular goiter, high in effective rate, small in pain of a patient, and free of toxic or side effects.

The invention relates to a traditional Chinese medicine for treating goiter, which comprises the components in parts by weight: 30 parts of self-heal, 25-35 part of seaweed, 15-20 parts of laminaria, 15-20 parts of taraxacum and 10-15 parts of thunberg fritillary bulb. The traditional Chinese medicine for treating goiter has the advantages of no side effect, favorable treatment effect and high cure speed.

The invention relates to a traditional Chinese medicine preparation for treating liver depression and qi stagnation type thyroid cancer. The traditional Chinese medicine preparation is prepared from the following raw material medicines in parts by weight: 13-16 parts of vinegar fried radix bupleuri, 8-13 parts of rhizoma cyperi, 7-11 parts of citrus reticulate, 30-35 parts of lysimachia christinae hance, 13-18 parts of fructus polygoni orientalis, 11-15 parts of radix scrophulariae, 20-30 parts of lycium barbarum, 8-13 parts of dried tangerine or orange peel, 15-20 parts of pinellia ternate, 25-30 parts of oldenlandia diffusa, 15-20 parts of saxifraga stolonifera, 11-15 parts of salvia miltiorrhiza, 14-19 parts of verbena officinalis and 15-20 parts of wild tobacco leaves. The formula has the effects of soothing liver-qi stagnation, reducing phlegm and softening hard mass, invigorating the blood and removing swelling, clearing away heat and toxic materials as well as removing stasis and eliminating goiter and is remarkable in effect on liver depression and qi stagnation type thyroid cancer, and in addition, the traditional Chinese medicine preparation can be prepared into multiple dosage forms which are convenient to carry over and use.

The invention discloses a traditional Chinese medicine for treating goiter. The traditional Chinese medicine is prepared from the following eight traditional Chinese medicines, including peach kernel, curcuma zedoary, radix bupleuri, ternate buttercup root, the seed of cowherb, aspongopus chinensis dallas, ground beeltle and centipede. The preparation method comprises the following steps: (1) extracting volatile oil from curcuma zedoary and radix bupleuri by using a steam distillation method; (2) decocting dregs left after the volatile oil is extracted from curcuma zedoary and radix bupleuri together with peach kernel, ternate buttercup root and the seed of cowherb in water and extracting, mixing the extracting solution with the filtrate obtained after the volatile oil is extracted in the step (1), and concentrating into extract; (3) grinding aspongopus chinensis dallas, ground beeltle and centipede into fine powder; and (4) adding auxiliary materials into the extract, the fine powder and the volatile oil to prepare tablets or cream paste. The hardness of the tablets can be over 12Kg, the friability is lower than 0.5 percent, the disintegration time limit is reduced from over 60 minutes to less than 40 minutes, the storage period is prolonged from one year to two years, and during the period, the product does not crack or leak oil. The cream paste is good in transdermal absorption effect, fast in drug absorption and high in blood concentration.

The invention relates to an external Chinese medicament for treating goiter and belongs to a Chinese medicinal preparation. The invention provides an external Chinese medicament with good treatment effect on goiter. The external Chinese medicament adopts the following technical scheme: 15 to 30 grams of semen perillae acutae, 15 to 30 grams of officinal magnolia bark, 15 to 30 grams of nutgrass galingale rhizome, 15 to 30 grams of radix curcumae, 15 to 30 grams of raw oyster shell, 15 to 30 grams of rhizoma pinelliae preparata, 15 to 30 grams of tangerine peel, 15 to 30 grams of thunberg fritillary bulb, 15 to 30 grams of turtle shell and 15 to 30 grams of musk are mixed to prepare the external Chinese medicament.

The invention relates to a traditional Chinese medicine, especially to a traditional Chinese medicine for treating goiter. The traditional Chinese medicine for treating goiter is prepared from the following bulk drugs, by weight, 9-15 parts of catnip, 5-10 parts of cassia twig, 5-15 parts of achyranthes root, 6-12 parts of radix paeoniae rubrathe, 5-15 parts of frankincense, 9-15 parts of Sambucus chinensis, 5-10 parts of arctium fruit, 10-20 parts of prunella vulgaris, 10-15 parts of natural indigo, 10-15 parts of Poria cocos, 10-20 parts of talcum, 3-10 parts of Sinapis alba and 10-15 parts of concha haliotidis. The traditional Chinese medicine for treating goiter is a pure Chinese herbal medicine, has effects of softening hardness and dissipating binds, promoting blood circulation to remove blood stasis, soothing the liver and resolving depression and rectifying qi and transforming phlegm, can be used fundamentally for overall conditioning treatment, can be used to specifically treat goiter so as to achieve the purpose of regaining health, is safe and reliable, has definite and rapid therapeutic effects, is painless, and has no toxic or side effect. Meanwhile, the traditional Chinese medicine for treating goiter has advantages of simple technology and good curative effect, and is convenient to use. Effective rate of the traditional Chinese medicine reaches up to 100%.

The external traditional Chinese medicine preparation comprises the following raw materials in parts by weight: 15-25 parts of dragon bone, 18-25 parts of oyster, 18-22 parts of rhizoma corydalis, 15-25 parts of asarum, 15-25 parts of eupolyphaga, 18-25 parts of semen momordicae, 3-8 parts of borneol, 16-23 parts of honeysuckle, 16-22 parts of dandelion, 14-22 parts of selfheal, 15-22 parts of turtle shell, 15-22 parts of thunberg fritillary bulb, 9-15 parts of ligusticum wallichii, 8-10 parts of angelica sinensis and 4-12 parts of rhizoma cyperi. The traditional Chinese medicine composition has remarkable effects of regulating qi-flowing for removing phlegm, eliminating goiter and resolving masses, nourishing yin to lessen fire and calming heart and liver, can be used for fundamentally treating thyroid nodules, has the total effective rate of 95% and has no adverse reaction.

The invention discloses a traditional Chinese medicine for treating phlegm-accumulation and blood-stasis syndrome type hyperthyroidism. The traditional Chinese medicine is characterized by comprising medicinal materials in parts by weight as follows: 9-11 parts of raw concha meretricis seu cyclinae, 9-11 parts of raw oyster shells, 4-6 parts of radix scrophulariae, 4-6 parts of seaweed, 4-6 parts of kelp, 23-26 parts of fritillaria cirrhosa, 23-26 parts of thunberg fritillary bulb, 23-26 parts of liquorice, 23-26 parts of phellodendron bark, 4-6 parts of common burreed rhizome, 4-6 parts of curcuma zedoary and 4-6 parts of red-rooted salvia roots. According to the traditional Chinese medicine, the appropriate medicinal materials and proportions of the medicinal materials are adopted, and the medicinal materials cooperate with one another and act synergistically, so that the prepared traditional Chinese medicine has functions of activating blood circulation, softening hard mass, eliminating goiter, removing stasis, nourishing yin, purging intense heat, smoothening liver, dispelling melancholy and relieving stagnant qi and can be used for treating the phlegm-accumulation and blood-stasis syndrome type hyperthyroidism effectively, and application of the traditional Chinese medicine to 46 patients within three years indicates that the effective rate is up to 87%.

The present invention relates to a Chinese medicine composition and its preparation process. In particular, it relates to a Chinese medicine prescription for curing the diseases of exophthalmus due to goiter disease (hyperthyroidism), hyperhidrosis, vexation, palpitation, diabetes and tremor of limbs, etc, and its preparation process. Said invention can be made into dripping pills and soft capsule preparation.

The invention discloses an anti-tumor combined medicine which comprises a sugar medicine and a traditional Chinese medicine composition, wherein the sugar medicine is at least prepared from leprin acetylsugar, coprinus comatus polysaccharide and cellobiose; the weight ratio of the sugar medicine to the traditional Chinese medicine composition is 1: (2 to 5); the mass ratio of the leprin acetylsugar to the coprinus comatus polysaccharide to the cellobiose is 1: (4 to 6): (1 to 2). After the leprin acetylsugar, the coprinus comatus polysaccharide and the cellobiose in the anti-tumor combined medicine disclosed by the invention are cooperated with the traditional Chinese medicine composition at a specific ratio, a synergetic effect is achieved, and the disease resistance of a human body can be enhanced; under the action of enhancing the immune function, the defense mechanism in an organism is improved, reappear and transfer of a tumor are prevented, and an extremely good treating effect is achieved on the tumor; the anti-tumor combined medicine has effects of treating or preventing digestive system cancers, leukemia, pituitary adenoma, small cell lung carcinoma, cancerous goiter and astrocyte tumor and has good clinical application prospect.

The present invention belongs to the technology field of medicinal and edible formula and new resource food, and specifically provides medicine formula food, specific medical formula food or non-specific medical formula food for cancerous goiter patients to eat; according to the requirement of "General principles of formula food for special medical purposes", combining the physical characteristics of the cancerous goiter patients, and according to the essence theory of traditional Chinese medical science, the formula food is prepared by mixing a reasonable compatibility of a variety of "medicinal and edible" traditional Chinese medicines, a variety of SBE pre-hydrolysis technology extracted medicinal and edible traditional Chinese medicine essences, various microencapsulated probiotic bacteria, biological enzymolysis extracted short chain polypeptides, prebiotics, amino acids, carbohydrates, health-care functional lipa, and various vitamins and minerals, and other processes. The formula food not only can act as a single source of nutrition to meet the nutritional requirements of the cancerous goiter patients, but also can play roles in detoxicating and eliminating stagnation, promoting blood circulation for removing blood stasis, reinforcing qi and nourishing blood, nourishing yin and removing heat, dispelling residual toxin, dispelling cancer and eliminating goiter and enhancing immunity.

The mastoproliferation treating medicine of the present invention is prepared with nine kinds of Chinese medicinal materials including green tangerine orange peel, curcuma root, corydalis tuber, chinaberry fruit, pinellia tuber, etc. and through stoving, grinding, 120-mesh sieving, honeying into bolus of 9.5 g each. The medicine has the functions of alleviating mental depression, removing blood stasis and dissipating mass and is used as treat mastoproliferation mainly and can be also used for treating goiter, subcutaneous nodule, etc.

The invention discloses a HPLC (High Performance Liquid Chromatography) fingerprint spectrum of a tablet capable of promoting blood circulation and eliminating a goiter. The method for preparing the fingerprint spectrum comprises the following steps that: independently detecting the solution of a sample for testing, hybrid reference substance solution, singe medicine material sample solution and sample-lacking negative sample solution on a high performance liquid chromatograph, wherein the high performance liquid chromatograph contains an ultraviolet detector, the set detection wavelength of the ultraviolet detector is 240-260nm, the stationary phase of the high performance liquid chromatograph is a C18 bonded silica gel chromatographic column, a mobile phase A is acetonitrile, and a mobile phase B is 0.05-0.2% trifluoroacetic acid aqueous solution; and adopting gradient elution. The spectrum contains 15 pieces of common fingerprint peaks, the fingerprint spectrum can be used for carrying out affiliation positioning and content measurement on eight index components and five traditional Chinese medicine ingredients in the tablet capable of promoting a blood circulation and eliminating the goiter, so that the comprehensive detection of the chemical ingredients of the tablet capable of promoting a blood circulation and eliminating the goiter can be realized, and the internal quality of the traditional Chinese medicines can be more comprehensively reflected and controlled.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine formula preparation for treating thyroid nodules and a preparation method of the traditional Chinese medicine formula preparation. The traditional Chinese medicine formula preparation comprises the following raw materials: spica prunellae, oldenlandia diffusa, edible tulip, angelica sinensis, thunberg fritillary bulb, dandelion, spina gleditsiae, radix curcumae, semen cuscutae, curcuma zedoary, campsis grandiflora, platycodon grandiflorum, radix scrophulariae and liquorice. Through reasonable compatibility of the traditional Chinese medicine raw materials and optimization of the preparation process, the traditional Chinese medicine formula preparation can effectively improve nodule symptoms of patients and has high clinical application value. All the medicines are used together to achieve the effects of eliminating stagnation, eliminating goiter, soothing liver-qi stagnation and promoting blood circulation to remove blood stasis, the thyroid nodules of the patients can be remarkably inhibited and reduced, the thyroid nodule level of the patients is not affected, safety is high, and toxic and side effects are avoided.

The invention discloses a traditional Chinese medicine preparation for treating the breast fibroadenoma. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 20 to 30 g of scorpion, 10 to 20 g of Chinese thorowax root, 10 to 20 g of selfheal, 10 to 20 g of the seed of cowherb, 10 to 20 g of Hailongdan, 10 to 20 g of curcuma zedoary, 10 to 20 g of bombyx batryticatus, 10 to 20 g of stir-baked turtle shell, 10 to 20 g of pericarpium citri reticulatae viride, 8 to 15 g of ostracean, 8 to 12 g of cornu cervi degelatinatum, 8 to 12 g of seaweed, 8 to 12 g of airpotato yam, 8 to 12 g of honeysuckle and 8 to 12 g of forsythia suspense. The selected raw materials are excellent in compatibility and take effects of relieving liver for smoothing qi, invigorating spleen and kidney, clearing heat and dissipating phlegm, eliminating stagnation and removing symptoms and promoting circulation and removing stasis together so as to achieve the effects of eliminating goiter and resisting tumor. The traditional Chinese medicine preparation for treating the breast fibroadenoma is worthy of clinical popularization and application.