102 results about "Goiter" patented technology

A traditional Chinese medicine for curing subacute thyroiditis belongs to a traditional Chinese medicine for curing swollen masses goiter. The components contain: 15g of Chinese thorowax root, 15g of baical skullcap root, 15g of pinellia tuber, 15g of Chinese angelica,15g of turmeric root tuber, 15g of zedoray rhizome, 15g of turtle shell, 15g of radix semiaquilegiae, 15g of weeping forsythia capsule, 15g of seaweed, 15g of lucid ganoderma, 15g of tree peony bark, 20g of common selfheal fruit-spike, 20g of bulbus fritillariae thunbergii, 20g of figwort root, 20g of spreading hedyotis herb, 20g of roasted himalayan teasel root, 20g of prepared flowery knotweed root, 30g of milkvetch root, 30g of heterophylly falsesatarwort, 30g of oyster and 10g of dried leech; the invention has the auxiliary prescriptions that: for severe heat, the common selfheal fruit-spike is added to 30g of, and 10g of common anemarrhena rhizome is added; for severe pain, 10g of platycodon root, 10g of blackberrylily rhizome and 10g of paris root are added. The compatibility of the traditional Chinese medicine is simple; the medicine used in the prescription is fully natural herbal medicine, which is easy to collect and use; the preparation method is simple; the effects for taking and curing are good; the cost of the medicine is low, and the medicine is in particular suitable for the people living in remote villages far from towns; the cost is low for curing the people suffering from subacute thyroiditis, which solves the problem that the local area lacks medical conditions to cure the disease because of low household income and poor living condition.

The invention discloses a traditional Chinese medicine composition for treating subacute thyroiditis. The composition is a preparation prepared from the following raw materials by weight: 15-30 parts of hedyotis diffusa, 9-15 parts of honeysuckle, 15-30 parts of dandelion, 15-30 parts of Chinese violet, 9-15 parts of root of common peony, 9-15 parts of radix scrophulariae, 9-15 parts of peach kernel, 9-15 parts of baked turtle shell and 15-30 parts of sweet wormwood. According to clinical study on the treatment of subacute thyroiditis, the traditional Chinese medicine composition provided by the invention has total effective rate of 93.34%, which is significantly better than 73.33% of a prednisone group, and can effectively reduce erythrocyte sedimentation rate and CRP of subacute thyroiditis patients, and effectively improve clinical symptoms of the patients; although the cooling time, improvement time of neck pain and regression time of neck tenderness are longer than those of the prednisone group, the goiter or nodule disappearance time shows no obvious difference from those of the prednisone group; relapse rate after drug withdrawal is 3.33%, which is significantly lower than 20% of the prednisone group; and the composition has little adverse reaction, which is significantly lower than that of the prednisone group. The invention also discloses a preparation method of the traditional Chinese medicine composition granules.

A traditional Chinese medicine for curing hashimoto's thyroiditis belongs to a traditional Chinese medicine for curing swollen masses goiter. The components contain: 9g of Chinese thorowax root, 9g of turmeric root tuber, 9g of nutgrass galingale rhizome, 9g of Baical Skullcap Root, 12g of Akebia Fruit, 12g of Bidens bipinnata L., 12g of Tuckahoe, 12g of Peach Seed, 30g of Milkvetch Root, 30g of Isatis Root, 20g of dried date and 6g of sward. The substances in the prescription are made from natural traditional Chinese medicine plus traditional preparing methods. The materials are easy to collect, the prescription and the preparation methods are simple, and the cost of medicine preparation is low. The compatibility of the traditional Chinese medicine is simple; the medicine used in the prescription is fully natural herbal medicine, which is easy to collect and use; the preparation method is simple; the effects for taking and curing are good; the cost of the medicine is low, and the medicine is in particular suitable for the people living in remote villages far from towns; the cost is low for curing the people suffering from hashimoto's thyroiditis, which solves the problem that the local area lacks medical conditions to cure the disease because of low household income and poor living condition.

The invention relates to the field of pharmaceutical chemistry, in particular to medical use of 34 compounds and medicinal composition containing the compounds, particularly use as Polo like kinase 1 inhibitor. Diseases associated with the Polo like kinase 1 inhibitor include melanoma, liver cancer, kidney cancer, acute leukemia, non-small-cell lung cancer, prostatic cancer, cancerous goiter, skin cancer, colorectal cancer, pancreatic cancer, ovarian cancer, breast cancer, myelodysplastic syndromes, esophageal cancer, gastrointestinal tract cancers or mesothelioma.

The invention discloses a traditional Chinese medicine composition for treating qi goiter, which is prepared from the following active pharmaceutical ingredients: 15 parts of radix bupleuri, 15 parts of lychee seed, 15 parts of Aspongopus, 15 parts of Jasminum grandiflorum, 12 parts of radix curcumae, 50 parts of laminaria, 50 parts of seaweed, 20 parts of mother-of-pearl, 20 parts of tortoise plastron, 20 parts of testa trionidis, 20 parts of dragon bone, 20 parts of oyster, 20 parts of swimming bladder gelatin, 20 parts of wolfberry fruit, 18 parts of radix paeoniae alba, 18 parts of glossy privet fruit, 20 parts of radix asparagi, 50 parts of raw hawthorn, 15 parts of costus root, 10 parts of Mangnolia officinalis and 12 parts of licorice root. The traditional Chinese medicine composition for treating qi goiter disclosed by the invention has the advantages of no toxic or side effect, obvious curative effect, wide medicine sources and low price; and the effective rate for treating qi goiter is 96%, and the cure rate is 88%.

The invention discloses a saliva proteome decision-making tree diagnosis model for screening thyroid cancer, and a construction method of the tree. The construction method comprises the following steps: collecting the saliva of patients with a thyroid cancer, patients with benign nodular goiter, and healthy people, standing, carrying out centrifugal treatment and the like, and combining with an NP20 chip; detecting the chip by adopting a PBS type-II protein chip reader, and automatically acquiring data by adopting Proteinchip Software 3.2.1 analysis software; carrying out bioinformatics statistic analysis; and building the diagnosis model by comparing saliva differential protein between a thyroid cancer group and a healthy control group, which is composed of four protein peaks with mass-to-charge ratios (M/Z) of 3491.10, 3642.28, 4315.10 and 7424.63 in a saliva protein mass spectrum, and by comparing saliva differential protein between a thyroid cancer group and a benign nodular goiter group, which is composed of four protein peaks with mass-to-charge ratios (M/Z) of 2587.38, 3346.06, 3584.20 and 8054.57 in the saliva protein mass spectrum. The construction method disclosed by the invention is simple, non-invasive, high in operability, high in specificity and high in sensibility; the diagnosis model provides a specific marker for early diagnosis and qualitative diagnosis levels for the thyroid cancer.

A traditional Chinese medicine for remedying the gall belongs to the traditional Chinese medicine for remedying the goiter. The components contain: 15g of bupleurum roots, 12g of orange fruits, 12g of tangerine peels, 12g of rhizome of nutgrass galingale, 9g of Szechwan lovage rhizome, 9g of peony roots and 6g of liquorice. The dosage materials in the prescription are all made from natural traditional Chinese herbal medicines by the traditional processing method. The materials can be easily gotten; the prescription and the preparation method are simple; the expense for preparing the medicine is low. The compatibility of the traditional Chinese herbal medicines is simple; the medicines used in the medicine prescription are all natural herbal medicines which can be conveniently gotten and used; the manufacturing method is simple; the curative effect after being taken is good; the medicine price is cheap, and the medicine is especially fit for people who live at the remote small villages away from villages and towns to use. The treatment expense for the patient with the disease of the gall is low, which solves the treatment problem which is caused by low family income, poor living and lack of local medical treatment condition.

A Chinese traditional medicine for curing goiter belongs to the Chinese traditional medicine for curing goitre. The ingredients of the medicine (with weights) are: alga 6g, kelp 6g, air potato yam rhizome 6g, frankincense 6g and borneol 3g. The medicines used in the prescription are all natural herbs and the Chinese traditional medicine is processed with traditional method; the fetching of material is convenient and the prescription and manufacture method are simple; the expense for manufacturing the medicine is low. The composition of the Chinese herbal medicine is simple and the medicines used in the prescription are all natural ones and the fetching and use are convenient; the manufacture method is simple and the effect is excellent; the price is low; in this way, the herbal medicine is especially fit for people living in remote villages far away from counties and towns; the curing expense for patients with the disease of goitre is low which solves the problem that the household income is low and the life is poor and the medical conditions is deficient locally.

The invention relates to a drug for treating nodular goiter. The drug is prepared from the following traditional Chinese medicine raw materials by weight: 1-5g of herb of white clover, 2-5g of stem of sargentgloryvine, 3-7g of oval kumquat root, 2-5g of root of kerr treebine, 3-10g of Indian melothria root, 5-8g of sinkiang fritillary bulb, 1-5g of cynanchum mooreanum, 10-20g of sweet potatoes, 5-10g of allium macrostemon, 3-5g of resina populi, 2-6g of ulva, 2-5g of stellaria aquatica and 1-3g of kirilow rhodiola rhizome and root. The drug disclosed by the invention is prepared from pure traditional Chinese medicine raw materials, has the effects of promoting qi and clearing liver fire, reducing phlegm and resolving masses, warming middle warmer and supporting yang, softening hard mass and removing cervical mass, nourishing yin and promoting blood flow, realizes determination of etiologic factors based on visceral pattern identification and precisely determines pathogenesis, is exact and remarkable in curative effect of treating nodular goiter, high in effective rate, small in pain of a patient, and free of toxic or side effects.

The invention relates to a traditional Chinese medicine for treating goiter, which comprises the components in parts by weight: 30 parts of self-heal, 25-35 part of seaweed, 15-20 parts of laminaria, 15-20 parts of taraxacum and 10-15 parts of thunberg fritillary bulb. The traditional Chinese medicine for treating goiter has the advantages of no side effect, favorable treatment effect and high cure speed.

The invention relates to a traditional Chinese medicine preparation for treating liver depression and qi stagnation type thyroid cancer. The traditional Chinese medicine preparation is prepared from the following raw material medicines in parts by weight: 13-16 parts of vinegar fried radix bupleuri, 8-13 parts of rhizoma cyperi, 7-11 parts of citrus reticulate, 30-35 parts of lysimachia christinae hance, 13-18 parts of fructus polygoni orientalis, 11-15 parts of radix scrophulariae, 20-30 parts of lycium barbarum, 8-13 parts of dried tangerine or orange peel, 15-20 parts of pinellia ternate, 25-30 parts of oldenlandia diffusa, 15-20 parts of saxifraga stolonifera, 11-15 parts of salvia miltiorrhiza, 14-19 parts of verbena officinalis and 15-20 parts of wild tobacco leaves. The formula has the effects of soothing liver-qi stagnation, reducing phlegm and softening hard mass, invigorating the blood and removing swelling, clearing away heat and toxic materials as well as removing stasis and eliminating goiter and is remarkable in effect on liver depression and qi stagnation type thyroid cancer, and in addition, the traditional Chinese medicine preparation can be prepared into multiple dosage forms which are convenient to carry over and use.

The invention discloses a traditional Chinese medicine for treating goiter. The traditional Chinese medicine is prepared from the following eight traditional Chinese medicines, including peach kernel, curcuma zedoary, radix bupleuri, ternate buttercup root, the seed of cowherb, aspongopus chinensis dallas, ground beeltle and centipede. The preparation method comprises the following steps: (1) extracting volatile oil from curcuma zedoary and radix bupleuri by using a steam distillation method; (2) decocting dregs left after the volatile oil is extracted from curcuma zedoary and radix bupleuri together with peach kernel, ternate buttercup root and the seed of cowherb in water and extracting, mixing the extracting solution with the filtrate obtained after the volatile oil is extracted in the step (1), and concentrating into extract; (3) grinding aspongopus chinensis dallas, ground beeltle and centipede into fine powder; and (4) adding auxiliary materials into the extract, the fine powder and the volatile oil to prepare tablets or cream paste. The hardness of the tablets can be over 12Kg, the friability is lower than 0.5 percent, the disintegration time limit is reduced from over 60 minutes to less than 40 minutes, the storage period is prolonged from one year to two years, and during the period, the product does not crack or leak oil. The cream paste is good in transdermal absorption effect, fast in drug absorption and high in blood concentration.

The invention relates to an external Chinese medicament for treating goiter and belongs to a Chinese medicinal preparation. The invention provides an external Chinese medicament with good treatment effect on goiter. The external Chinese medicament adopts the following technical scheme: 15 to 30 grams of semen perillae acutae, 15 to 30 grams of officinal magnolia bark, 15 to 30 grams of nutgrass galingale rhizome, 15 to 30 grams of radix curcumae, 15 to 30 grams of raw oyster shell, 15 to 30 grams of rhizoma pinelliae preparata, 15 to 30 grams of tangerine peel, 15 to 30 grams of thunberg fritillary bulb, 15 to 30 grams of turtle shell and 15 to 30 grams of musk are mixed to prepare the external Chinese medicament.

The invention relates to a traditional Chinese medicine, especially to a traditional Chinese medicine for treating goiter. The traditional Chinese medicine for treating goiter is prepared from the following bulk drugs, by weight, 9-15 parts of catnip, 5-10 parts of cassia twig, 5-15 parts of achyranthes root, 6-12 parts of radix paeoniae rubrathe, 5-15 parts of frankincense, 9-15 parts of Sambucus chinensis, 5-10 parts of arctium fruit, 10-20 parts of prunella vulgaris, 10-15 parts of natural indigo, 10-15 parts of Poria cocos, 10-20 parts of talcum, 3-10 parts of Sinapis alba and 10-15 parts of concha haliotidis. The traditional Chinese medicine for treating goiter is a pure Chinese herbal medicine, has effects of softening hardness and dissipating binds, promoting blood circulation to remove blood stasis, soothing the liver and resolving depression and rectifying qi and transforming phlegm, can be used fundamentally for overall conditioning treatment, can be used to specifically treat goiter so as to achieve the purpose of regaining health, is safe and reliable, has definite and rapid therapeutic effects, is painless, and has no toxic or side effect. Meanwhile, the traditional Chinese medicine for treating goiter has advantages of simple technology and good curative effect, and is convenient to use. Effective rate of the traditional Chinese medicine reaches up to 100%.

The external traditional Chinese medicine preparation comprises the following raw materials in parts by weight: 15-25 parts of dragon bone, 18-25 parts of oyster, 18-22 parts of rhizoma corydalis, 15-25 parts of asarum, 15-25 parts of eupolyphaga, 18-25 parts of semen momordicae, 3-8 parts of borneol, 16-23 parts of honeysuckle, 16-22 parts of dandelion, 14-22 parts of selfheal, 15-22 parts of turtle shell, 15-22 parts of thunberg fritillary bulb, 9-15 parts of ligusticum wallichii, 8-10 parts of angelica sinensis and 4-12 parts of rhizoma cyperi. The traditional Chinese medicine composition has remarkable effects of regulating qi-flowing for removing phlegm, eliminating goiter and resolving masses, nourishing yin to lessen fire and calming heart and liver, can be used for fundamentally treating thyroid nodules, has the total effective rate of 95% and has no adverse reaction.

The invention discloses a traditional Chinese medicine for treating phlegm-accumulation and blood-stasis syndrome type hyperthyroidism. The traditional Chinese medicine is characterized by comprising medicinal materials in parts by weight as follows: 9-11 parts of raw concha meretricis seu cyclinae, 9-11 parts of raw oyster shells, 4-6 parts of radix scrophulariae, 4-6 parts of seaweed, 4-6 parts of kelp, 23-26 parts of fritillaria cirrhosa, 23-26 parts of thunberg fritillary bulb, 23-26 parts of liquorice, 23-26 parts of phellodendron bark, 4-6 parts of common burreed rhizome, 4-6 parts of curcuma zedoary and 4-6 parts of red-rooted salvia roots. According to the traditional Chinese medicine, the appropriate medicinal materials and proportions of the medicinal materials are adopted, and the medicinal materials cooperate with one another and act synergistically, so that the prepared traditional Chinese medicine has functions of activating blood circulation, softening hard mass, eliminating goiter, removing stasis, nourishing yin, purging intense heat, smoothening liver, dispelling melancholy and relieving stagnant qi and can be used for treating the phlegm-accumulation and blood-stasis syndrome type hyperthyroidism effectively, and application of the traditional Chinese medicine to 46 patients within three years indicates that the effective rate is up to 87%.

The invention discloses a HPLC (High Performance Liquid Chromatography) fingerprint spectrum of a tablet capable of promoting blood circulation and eliminating a goiter. The method for preparing the fingerprint spectrum comprises the following steps that: independently detecting the solution of a sample for testing, hybrid reference substance solution, singe medicine material sample solution and sample-lacking negative sample solution on a high performance liquid chromatograph, wherein the high performance liquid chromatograph contains an ultraviolet detector, the set detection wavelength of the ultraviolet detector is 240-260nm, the stationary phase of the high performance liquid chromatograph is a C18 bonded silica gel chromatographic column, a mobile phase A is acetonitrile, and a mobile phase B is 0.05-0.2% trifluoroacetic acid aqueous solution; and adopting gradient elution. The spectrum contains 15 pieces of common fingerprint peaks, the fingerprint spectrum can be used for carrying out affiliation positioning and content measurement on eight index components and five traditional Chinese medicine ingredients in the tablet capable of promoting a blood circulation and eliminating the goiter, so that the comprehensive detection of the chemical ingredients of the tablet capable of promoting a blood circulation and eliminating the goiter can be realized, and the internal quality of the traditional Chinese medicines can be more comprehensively reflected and controlled.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine formula preparation for treating thyroid nodules and a preparation method of the traditional Chinese medicine formula preparation. The traditional Chinese medicine formula preparation comprises the following raw materials: spica prunellae, oldenlandia diffusa, edible tulip, angelica sinensis, thunberg fritillary bulb, dandelion, spina gleditsiae, radix curcumae, semen cuscutae, curcuma zedoary, campsis grandiflora, platycodon grandiflorum, radix scrophulariae and liquorice. Through reasonable compatibility of the traditional Chinese medicine raw materials and optimization of the preparation process, the traditional Chinese medicine formula preparation can effectively improve nodule symptoms of patients and has high clinical application value. All the medicines are used together to achieve the effects of eliminating stagnation, eliminating goiter, soothing liver-qi stagnation and promoting blood circulation to remove blood stasis, the thyroid nodules of the patients can be remarkably inhibited and reduced, the thyroid nodule level of the patients is not affected, safety is high, and toxic and side effects are avoided.

The invention discloses a preparation and utilization method of moxibustion healthcare paste for external use. The moxibustion healthcare paste is characterized by being prepared from 15-20% of natural magnetic micropowder, 4-6% of tourmaline micropowder, 4-6 parts of far infrared ceramic micropowder, 10-15% of Chinese herbal medicines, 5-10% of healthcare paste matrix, 20-30% of beeswax, 10-15% of red lead and 20-30% of medicinal vaseline. The moxibustion healthcare paste is applied to human acupoints; after the healthcare paste is heated to melt and naturally cooled for about 10-15min priorto being spread at a cleaned affected pain part, and skin activating, skin detoxifying, great heat absorbing and preserving effects, uniformity in heat dissipation and temperature uniformity are realized; meridian activating, wind expelling, cold removing, blood circulation activating, stasis removing and goiter and tumor removing can be realized, and pain relapse is avoided; treatment of headache, toothache, prosopalgia, sore thorat, chest hypochondrium, epigastric pain, stomachache, gout, neck-shoulder and lumbocrural pain, protrusion of intervertebral disc, sciatica, rheumatalgia and spinalpain can be realized; the moxibustion healthcare paste can be conveniently applied to different human body parts, avoids hardening and flowing, is solidified after being removed from a human body andcan be repeatedly heated for use.