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Pharmaceutical composition for treating myocarditis and preparation method of pharmaceutical composition

A composition and technology of myocarditis, applied in the field of pharmaceutical preparations, can solve the problems of toxic and side effects, slow effect, and insignificant curative effect, and achieve the effect of no toxic and side effects, fast onset of effect, and short course of treatment

Inactive Publication Date: 2015-07-22
郭延举
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] However, current drugs for the treatment of myocarditis are slow to take effect, insignificant in curative effect, and have toxic and side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0073] When the dosage form of the pharmaceutical composition is a tablet, its preparation method comprises the following steps:

[0074] The first step is to mix the raw medicinal materials in the pharmaceutical composition in proportion, add ethanol with an alcohol concentration of 85-95% that is 2-4 times the mass of the mixture, heat and reflux for 1-3 hours, extract, and filter to obtain the first an extract solution; add ethanol with an alcohol concentration of 85-95% of 1-2 times the mass of the medicine residue obtained by filtering, heat and reflux for 1-3 hours, extract, and filter to obtain a second extract solution; The first extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0075] In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1 to 2 hours, pulverized, and sieved to obtain an ultrafine powder of 300 mesh to 400 mes...

Embodiment 1

[0088] Example 1 tablet

[0089] The preparation process of the tablet of the present invention is: get Acanthopanax 250g, Cinnabar 20g, Polygala 450g, Hippocampus 260g, Guizhi 140g, Galangal 200g, Cystia 220g, Poria 400g, Periwinkle 250g, Amber 420g, Daigo 220g, Dendrobium 300g, 40g valerian, 450g apocynum, 320g magnet, 200g night vine, 20g evergreen, 330g lotus seed, 200g Alisma, 310g purple river car, 120g dried ginger, 450g dried ginger, 330g frangipani flower and 150g acacia bark;

[0090] The first step is to mix the raw medicinal materials in the pharmaceutical composition in proportion, add ethanol with an alcohol concentration of 85% that is 3 times the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract; filter to obtain The dregs of the dregs are added with 90% ethanol with an alcohol concentration of 1.5 times the quality of the dregs, heated to reflux for 2 hours, extracted, and filtered to obtain the second extract; t...

Embodiment 2

[0093] Embodiment 2 oral liquid

[0094] The preparation process of the oral liquid of the present invention is: get Acanthopanax 270g, Cinnabar 20g, Polygala 320g, Hippocampus 280g, Guizhi 160g, Galangal 250g, Cystia 150g, Poria 400g, Periwinkle 220g, Amber 420g, Dendrobium 140g, Dendrobium 200g, 30g valerian, 480g apocynum, 340g magnet, 220g night vine, 30g evergreen, 350g lotus seeds, 200g Alisma, 160g Ziheche, 110g dried ginger, 350g dried ginger, 230g jasmine flower and 100g acacia bark;

[0095] In the first step, mix apocynum, magnetite, twig, evergreen, lotus seeds, Alisma and purple river cartilage, add 90% ethanol with 7 times the alcohol concentration relative to the mixture, and reflux extraction for 3 times, each time for 4 hours, Filter separately, combine each filtrate, recover ethanol, concentrate to a paste with a relative density of 1.38 at 70°C, and set aside;

[0096] The second step is to mix the remaining raw medicinal materials in proportion, add 6 time...

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Abstract

The invention discloses a pharmaceutical composition for treating myocarditis and a preparation method of the pharmaceutical composition. The pharmaceutical composition is prepared from the following raw herbal materials: acanthopanax, cinnabar, polygala tenuifolia, sea horse, cassia twig, Chinese ginger, elsholtzia, fushen, catharanthus roseus, amber, finest cream, dendrobe, valerian, evergreen, apocynum venetum, magnet, tuber fleeceflower stem, lotus seed, rhizoma alismatis, placenta hominis, silverweed cinquefoil root, fortune silene herb with root, officinal cynanchum root, jasminum laurifolium, cotton bud, dried ginger, jasminum grandiflorum and cortex albiziae. The pharmaceutical composition has the beneficial effects of nourishing heart and tonifying qi, warming heart yang, soothing the nerves and calming, has the effects of dredging heart vessels, and nourishing yin and clearing heat, and further has the advantages of quick effect-taking, high effective rate, exact curative effect, short treatment course, no toxic or side effects, low price, and the like.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a pharmaceutical composition for treating myocarditis and a preparation method thereof. Background technique [0002] Myocarditis refers to localized or diffuse inflammatory lesions of the myocardium caused by various etiologies. Inflammatory lesions may involve the myocardium, interstitium, vessels, pericardium, or endocardium. The etiology can be various infections, autoimmune reactions and physical and chemical factors. The course of the disease can be acute (within 3 months), subacute (3 to 6 months) and chronic (more than half a year). Viral myocarditis is more common in my country. [0003] Symptoms and signs of myocarditis: The clinical manifestations of myocarditis are mainly systemic symptoms of primary infection or primary disease, such as sleepiness, fever, and upper respiratory tract infection. The clinical manifestations related to myocardit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P9/00A61K35/50A61K33/26A61K35/20A61K35/10A61K35/60A61K33/28
Inventor 刘淑玲郭延举李兰荣
Owner 郭延举
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