495 results about "Upper respiratory tract infection" patented technology

The present invention provides methods for preventing, managing, treating and/or ameliorating a Respiratory Syncytial Virus (RSV) infection (e.g., acute RSV disease, or a RSV upper respiratory tract infection (URI) and/or lower respiratory tract infection (LRI)), otitis media (preferably, stemming from, caused by or associated with a RSV infection, such as a RSV URI and/or LRI), and/or a symptom or respiratory condition relating thereto (e.g., asthma, wheezing, and/or reactive airway disease (RAD)) in a subject, comprising administering to said human an effective amount of one or more antibodies that immunospecifically bind to one or more RSV antigens with a high affinity and/or high avidity. In some embodiments, one or more antibodies comprise a modified IgG constant domain, or FcRn-binding fragment thereof resulting in longer in vivo serum half-life. In particular embodiments the methods of the invention comprising administering to subject an effective amount of one or more modified antibodies that immunospecifically bind to one or more RSV antigens with an association rate (k_on) of at least 2×10⁵ M⁻¹s⁻¹ and a dissociation rate (k_off) of less than 5×10⁻⁴ s⁻¹.

The mouth breathing preventer device has a lip shield and a dental shield which are connected by a center tube. The center tube can be sealed to prevent air from entering the mouth or opened to allow for a saline solution or saliva substitute solution to be introduced into the mouth. The device prevents the mouth from dehydrating thereby restoring the self cleansing mechanism of the mouth. The device also helps prevent upper respiratory tract infection, snoring and lessens sinus irritation and middle ear infection.

An inhalable cold plasma mask device for generation of a breathable cold plasma for delivery to a patient. A biocompatible gas is received in a dielectric barrier discharge (DBD) device that is energized by an electrode that receives energy from a pulsed source. The DBD device can be grounded by a grounding structure. A grounding screen can be used prior to inhalation of the cold plasma. The inhalable cold plasma mask device includes the use of a single-layer or a two-layer approach to its construction. The inhalable cold plasma mask device can have one or two DBD devices. Such a device and associated method can be used to treat upper respiratory tract infections, as well as reducing inflammation, sinus and esophageal polyps in both size and frequency of occurrence.

The compositions of the present invention comprise a therapeutically effective amount of particles consisting of diphenhydramine or pharmaceutically acceptable salts thereof, optionally in combination with another drug such as pseudoephedrine, or phenylephrine and hydrocodone, in combination with rapidly-dispersing microgranules comprising a disintegrant and a sugar alcohol and/or a saccharide. These compositions are useful in treating the symptoms of one or more diseases or conditions in which diphenhydramine (alone or in combination with one or two other drugs) is a therapeutically effective, e.g. allergic rhinitis, sinusitis, upper respiratory tract infections, motion sickness, Parkinson's disease, insomnia, the common cold, and nighttime pain management, particularly for subjects or patients with dysphagia, and people ‘on the move’.

A powder injection for treating upper respiratory tract infection, acute tonsillitis, and pharyngitis is prepared from the honeysuckle flower's extract whose main component is chlorogenic acid, baicalein and water-soluble additive for injection. Its advantages are high curative effect and stability, and long storage time.

The invention relates to a traditional Chinese medicament combination for treating children pharyngolaryngitis, a preparation method and a quality control method thereof; and the medicament combination consists of raw herbal materials of honeysuckle, calculus bovis, blackberry lily, tinospora root, balloonflower and radix scrophulariae, etc. According to traditional Chinese medicament conventional technology, the raw herbal materials are prepared into various preparations suitable for clinical application, including tablets, capsules, oral liquid preparations, dropping pills, granules, etc. The quality control method comprises the qualitative identification of thin layer chromatography and the content determination of high performance liquid chromatography and the like. The medicament combination is used for treating influenza, upper respiratory tract infection, and swollen sore throat, erosion of mouth and tongue, cough with profuse sputum, pharyngitis and laryngitis, tonsillitis, fever and the like caused by lung excess heat with obvious curative effect.

The invention relates to a traditional Chinese medicine air freshening bactericide and a preparation process thereof. Use aromatic decontamination Chinese herbal medicine clove, mugwort leaf, angelica, atractylodes, magnolia, calamus, paeonol, and wild chrysanthemum according to a certain prescription ratio, clean selection, crushing, soaking, and steam distillation to extract the active ingredients, without adding dimethyl ether , Freon and other chemical ingredients harmful to the human body, without adding preservatives. Not only is it fragrant, it can quickly freshen the air and improve air quality, but it can also be refreshing, prevent upper respiratory tract infections, repel mosquitoes, and inhibit bacteria. It can also be used as a humidifier or electric heater humidifying fluid. Therefore, it is not only a necessity for people to improve air quality at present, but also a new choice for eliminating skin itching, preventing mosquito bites and eliminating the invasion of germs on the body surface.

The invention discloses a Chinese medicinal preparation for treating infantile upper respiratory tract infection and a preparation method thereof. The Chinese medicinal preparation comprises the following raw material medicaments: Indian buead, ephedra herb, kudzuvine root, white mustard seed, schizonepeta spike, cicada slough, platycodon root, astragalus, gypsum, mint, tangerine peel, divaricate saposhnikovia root, baical skullcap root and heartleaf houttuynia herb. For infants accompanied by sore throat and antiadoncus, watermelon frost and honeysuckle flower are added into the raw material medicaments; for infants accompanied by pyrexia and high fever, weeping forsythia, indigowoad root and gardenia are added into the raw material medicaments; for infants accompanied by poor appetite and indigestion, charred triplet and chicken's gizzard-membrane are added into the raw material medicaments; and for infants accompanied by cough with excessive phlegm, sessile stemona root and unibract fritillary bulb are added into the raw material medicaments. In the Chinese medicinal preparation, pungent warm is matched with acrid cold to dredge sweat pores and cleanse intrinsic heat; and the intrinsic heat is expelled by aiding with pivoting and elevating, and sour-sweet medicaments are subjected to compatibility to nourish yin, clear yingfen and remove the intrinsic heat. The infantile upper respiratory tract infection is caused by exogenous pathogens and seasonal pathogenic factors due to abnormal changes in temperature, and is easy to produce the intrinsic heat, so heat syndromes are common clinically, and quick defervescence is the main treatment aim. The Chinese medicinal preparation has the strong effects of resisting virus, allaying the fever, resisting inflammation and enhancing organism immunity.

The invention belongs to natural medicine field and in particular relates to guaiane sesquiterpenoid with general formulaIwhich is distilled from Chinese herb ainsliaeafragrans; wherein R1 is OH or 0- beta-D-GIc; R2 is OH or H; R3 is alpha-H, beta-CH3 or =CH2. The invention further relates to the preparation method of the compound, the medicine combination with the compound as active component, and the application of the compound and the medicine combination thereof in curing acute or chronic inflammation and relevant diseases, including cervicitis, pelvic inflammation, endometritis, upper respiratory tract infection, quinsy as well as faucitis.

The invention relates to the field of traditional Chinese medicines, especially to a preparation method of an antiviral oral liquid. The antiviral oral liquid is prepared from Chinese herbal medicines, has effects of releasing heat, eliminating dampness, cooling the blood and detoxifying, and is used to treat wind-heat cold, fever caused by warm disease, upper respiratory tract infection, influenza and mumps virus infection diseases. The preparation method of the antiviral oral liquid is simple to operate and is suitable for large-scale production. The ratio of Chinese herbal medicines is scientific. And by the adoption of the preparation method, waste of the Chinese herbal medicines is avoided.

An Echinacea composition containing the immunosuppressive components of an Echinacea extract but not the immunostimulatory components is disclosed. A process for isolating Echinacea immunosuppressive components by extraction with lipophilic compounds is also disclosed. The Echinacea composition can be used for treatment of colds, flu, and other upper respiratory tract infections, inflammatory diseases, and immunomodulatory disorders.

The invention relates to Chinese herbal medicine sugar and tea drink preparation for preventing and treating cold, which is used to prevent and treat rhinitis, acute tonsil inflammation, laryngitis, bronchitis, pneumonia and other diseases caused by cold and upper respiratory tract infection. The preparation comprises schizonepeta, ledebouriella seseloides, peucedanum, perilla, campanulaceae, ginger, licorice, bupleurum, heracleum hemsleyanum michaux, rhizoma ligustici wallichii, tuckahoe, citrus aurantium, almond, dried orange peel, glucose and the like, and has the advantages of rich raw herb, easy preparation, convenient taking, strong targeting power, good therapeutic effect, no toxic and side effect and 100 percent total efficient rate of clinical application symptomatic treatment. Particularly, the Chinese herbal medicine sugar and tea drink preparation which is a technical innovation to the nowadays international medical application, and is researched, developed and carried forward makes up for the gap of the subject field, and is the significant progress of the research on the modern medicine and traditional Chinese herbal medicine straw tea culture, and the Chinese herbal medicine sugar and tea drink preparation.

An antiviral Chinese medicine in the form of pill, particle, or tablet for treating cold, upper respiratory tract infection, influenza and tonsillitis is prepared from 9 Chinese-medicinal materials including isatis root, gypsum, rehmannia root, etc. Its preparing process and quality control method are also disclosed.

The invention relates to an andrographis paniculata atomization inhalation solution preparation, and belongs to the field of pharmaceutical pharmacy, wherein the andrographis paniculata atomization inhalation solution preparation comprises (1) an andrographis paniculata effective component, and (2) an isotonic agent and a solvent. According to the present invention, the prepared andrographis paniculata atomization inhalation solution preparation makes up for the gap in the current domestic market, and is specifically designed for atomization inhalation patients, wherein the andrographis paniculata atomization inhalation solution preparation is directly inhaled into the respiratory system in an atomized form after the andrographis paniculata atomization inhalation solution preparation is atomized by an ultrasonic atomizer or an air compression type atomizer, such that the use is convenient; and compared to the andrographis paniculata oral liquid, the andrographis paniculata atomizationinhalation solution preparation of the present invention has the different administration route, has advantages of use dose reducing, rapid effect and improved safety, and can well treat upper respiratory tract infections, sore throat, cough with lung heat and the like.

The invention relates to a common anemarrhena polysaccharide extractive with immunosuppression activity and a preparation method and medicine purposes thereof. The preparation method comprising the steps of degreasing raw materials, extracting the degreased raw materials with water, precipitating the extracted material with alcohol, carrying out dialysis and ion-exchange column chromatography on the crude polysaccharide to eliminate proteins, pigments and molecular chemical components to produce an anemarrhena extractive. A huge amount of pharmacological experiments prove that common anemarrhena polysaccharide has an immunodepression activity and has the medical purposes of treating proinflammatory traumatic diseases, such as nephritis, pneumonia, upper respiratory tract infection, hepatitis, tonsillitis and diabetes.

The invention provides a compound angelica preparation, the dosage of the raw medicinal materials of which is calculated according to the weight, namely 10-30g of angelica, 5-15g of caladium and 2-8g of sophora Flavescens Ait. The preparation includes oral liquid, spray, and aerosol, dropping pill, capsule or tablet. Compared to the prior art, the preparation of the invention has remarkable effect on curing asthma, cough and expectoration, while the animal experiment also shows that the preparation has remarkable anti-inflammation and cough relieving actions on mice and has better asthma curing action on Guinea pig. Moreover, the preparation only contains three Chinese traditional medicines and is of refined formula, advanced preparation process and can be prepared to be various formulations like dropping pill, aerosol, spray, capsule and tablet and so on with easy administration. The beneficial effects of the preparation is further specified combining with the embodiment and the clinical experiment as below; the preparation can be applied in preparing drugs with actions of anti-inflammation, cough relieving and asthma curing, can also be applied in preparing drugs for treating acute and chronic bronchitis, chronic obstructive pulmonary diseases and upper respiratory tract infection respiratory diseases.

The present invention discloses an anoectochilus roxburghii-hosui pear health care beverage and a preparation method thereof. Each 500 ml of the health care beverage is prepared from the following raw materials: 90 g of fresh anoectochilus roxburghii, 100-360 g of hosui pear, 15-25 g of sucrose, 0.009 g of citric acid, 0.0375-0.0765 g of sodium erythorbate, and the balance of distilled water. According to the present invention, anoectochilus roxburghii and hosui pear are prepared into a mixed beverage, such that advantage complementation is achieved, the pear juice is sweet and refreshing, and unique flavor of the anoectochilus roxburghii is regulated; and the anoectochilus roxburghii-hosui pear health care beverage can be suitable for consumption populations with different ages and different genders, especially for hepatitis patients, pulmonary tuberculosis patients, constipation patients, acute and chronic tracheitis patients, upper respiratory tract infection patients, high blood pressure patients, heart disease patients and esophageal cancer patients.

The invention relates to a double-vanilla preparation, which is a medicament prepared by the following raw materials in part by weight: 50-600 parts of white honeysuckle flower, 50-600 parts of weeping forsythia, 50-600 parts of wrinkled gianthyssop herb, 50-300 parts of peppermint, 50-600 parts of lithospermum, 50-300 parts of wormwood leaf and 50-300 parts of raw licorice. The invention also provides a preparation method of the double-vanilla preparation, which comprises the following steps: boiling and distilling the white honeysuckle flower, weeping forsythia and the like in water for 1-20 times and for 0.5-5 hours and simultaneously collecting essential oil for standby, wherein water is added for soaking for 0-2 hours before boiling and distilling, the quantity of water is 5-20 times of the weight of the seven kinds of traditional Chinese medicines; filtering the boiled liquid until the relative concentration of the filtrate is 0.5-2; adding ethanol in the filtrate, standing and filtering; recovering ethanol until the filtrate is tasteless; adjusting a pH (Potential of Hydrogen) value: adjusting the pH value of the filtrate obtained by recovering the ethanol to 3-7; and diluting, filtering and disinfecting. The invention has good pesticide effect to upper respiratory tract infection, remarkable treatment effects, quicker fever abatement of patients with a hand-foot-mouth disease and deflorescence and good medicine properties; and as the atomization preparation is adopted, the medicine can be conveniently used, and compliance of patients is good.

The invention relates to a complex traditional Chinese medicine preparation for treating upper respiratory tract infection and a preparation method thereof. The complex traditional Chinese medicine preparation comprises the following raw materials: 10-25 parts of picria felterrae lour, 5-15 parts of herba sarcandrae, 5-15 parts of senecio, 5-13 parts of pubescent holly root and 1-5 parts of liquorice. The preparation method comprises the following steps: pulverizing a proper amount of picria felterrae lour into fine powders; adding water into residual picria felterrae lour, the herba sarcandrae, the senecio, and the like and extracting to obtain extracts; adding alcohol into the extracts to carry out alcohol deposition, filtration and concentration to form thick paste; uniformly mixing, drying and pulverizing the thick paste and the picria felterrae lour fine powder to form fine powders; and adding a proper number of auxiliary materials and uniformly mixing to prepare particles or adding general preparation auxiliary materials to prepare general solid oral administration preparation. According to clinical observation for many years, the traditional Chinese medicine preparation benzyrin tablet has the obvious treating effects on a patient with upper respiratory tract infection diseases, such as upper respiratory tract inflammation, bronchitis, rhinitis, pharyngolaryngitis, tonsillitis, and the like.

The invention discloses a method for preparing an indoor air virus pathogen invincible opponent. The indoor air virus pathogen invincible opponent prepared by menthol, thymol, weeping forsythia oil and radix bupleuri oil has the killing rate of between 76 and 99.9 percent to idemic encephalitis, influenza viruses, hand-foot-and-mouth disease, avian influenza, legionnella, pneumoniae, hepatitis C viruses, hepatitis A viruses, Staphylococcus albus, Staphylococcus aureus, Klebsiella pneumoniae, Candida albicans, typhoid viruses, Escherichia coli, cholera viruses, infectious germs and bacteria, and harmful germs and bacteria. The indoor air virus pathogen invincible opponent is mainly applied to rooms, schools, hospitals, hotels, air conditioners, automobiles, public places, and the like, and has obvious effect on the control of diseases such as influenza, upper respiratory tract infection. The indoor air virus pathogen invincible opponent has outstanding substantive characteristics and broad application prospect.

The invention relates to a traditional Chinese medicine composition capable of expelling wind, relieving exterior syndrome, clearing away the heat-evil and expelling superficial evils, composed of fermented soybean, figwort, mulberrt leaf, tangerine peel, weeping forsythia, mint, red peony root, honeysuckle, cicada skin, cogongrass rhizome, kudzuvine root, iastis root, hogfennel root, scullcap, schizonepeta spike, isatis leaf, cape jasmine, radix trichosanthis, Chinese tamarisk, concentrated powder of buffalo horn and an amount of pharmacueutic adjuvsnt. The traditional Chinese medicine composition mainly treats upper respiratory tract infection, influenza, measles, rubella. The traditional Chinese medicine composition is capable of expelling wind, relieving exterior syndrome, relieving the muscles and skin, promoting eruption, clearing away the heat-evil and expelling superficial evils. The traditional Chinese medicine composition has features of quick effect on upper respiratory tract infection, influenza, throat congestion, measles, rubella; convenient administration, small dosage, no side-effect and easier child acceptability.

The present invention discloses a kind of medicine powder for intravenous injection and its preparation process. The medicine is prepared with chlorogenic and baicalin as material. The medicine has obvious curative effect on upper respiratory tract infection, pneumonia and viral respiratory tract infection.

A dripping pill of dandelion herb for treating upper respiratory tract infection, sore, furuncle, enteritis, etc is prepared from dandelion herb. Its preparing process is also disclosed.

The invention belongs to the field of medical technology, and discloses a medicinal combination which contains ambroxol or its pharmaceutical acceptable salt and at least one anti-infective drug and their preparation methods and uses. Among them, the anti-infective drugs selected from: baicalin and/or 14-dehydroxylation-11, 12-two-dehydrogenating-andrographolide-3, 19-two succinic acid half ester salt, the drug combinations can be made to various pharmaceutical acceptable formulations; combinations are used to preparing and treating upper respiratory tract infection, chronic bronchitis, pneumonia and exfoliative viscous, expectoration difficulty and other disease leading by upper respiratory tract infection(such as acute, chronic bronchitis, bronchial asthma, bronchiectasis and phthisis confirmata and so on), and has synergic synergism and the stability is fine, its effect is improved greatly compared to only using same dosage alcaine ambroxol or baicalin or Yanhuning, it produces unexpected results and has extensive application prospects.