Compound angelica sinensis preparations and preparation and application

A technology of angelica and preparations, which is applied in anti-inflammatory agents, pill delivery, medical formulas, etc., can solve the problems of large dosage, high difficulty of Chinese patent medicines, and difficult quality control, etc., and achieves advanced preparation technology, anti-inflammatory and cough-relieving effects, good The effect of antiasthmatic effect

Active Publication Date: 2008-08-06
ZHEJIANG UNIV
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  • Summary
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  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, at present, the treatment of such respiratory diseases with traditional Chinese medicines is limited to the application of traditional Chinese medicine decoctions, and because most of them are large compound prescriptions with more than ten medicinal materials, it is difficult to make Chinese pa

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1: the preparation of oral liquid

[0024]Angelica 10g, Fritillaria 5g, Sophora flavescens 2g are decocted twice with water, the decoctions are combined, filtered, concentrated to an appropriate volume, preservative sodium benzoate is added, and divided into oral liquids.

Embodiment 2

[0025] Embodiment 2: the preparation of spray

[0026] Angelica 30g, Fritillaria 10g, Sophora flavescens 8g were extracted with ethanol for 3 times, filtered, combined extracts, concentrated, added Tween-80 and vitamin C after constant volume, and quantitatively divided to make a spray.

Embodiment 3

[0027] Embodiment 3: the preparation of aerosol

[0028] Angelica 12g, Fritillaria 15g, Sophora flavescens 6g were extracted with ethanol for 3 times, filtered and combined the extracts, concentrated, added an appropriate amount of PEG300 after constant volume, quantitatively distributed in aerosol pressure-resistant containers, and then pressed into an appropriate amount of propellant four Fluoroethane, made into aerosol.

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PUM

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Abstract

The invention provides a compound angelica preparation, the dosage of the raw medicinal materials of which is calculated according to the weight, namely 10-30g of angelica, 5-15g of caladium and 2-8g of sophora Flavescens Ait. The preparation includes oral liquid, spray, and aerosol, dropping pill, capsule or tablet. Compared to the prior art, the preparation of the invention has remarkable effect on curing asthma, cough and expectoration, while the animal experiment also shows that the preparation has remarkable anti-inflammation and cough relieving actions on mice and has better asthma curing action on Guinea pig. Moreover, the preparation only contains three Chinese traditional medicines and is of refined formula, advanced preparation process and can be prepared to be various formulations like dropping pill, aerosol, spray, capsule and tablet and so on with easy administration. The beneficial effects of the preparation is further specified combining with the embodiment and the clinical experiment as below; the preparation can be applied in preparing drugs with actions of anti-inflammation, cough relieving and asthma curing, can also be applied in preparing drugs for treating acute and chronic bronchitis, chronic obstructive pulmonary diseases and upper respiratory tract infection respiratory diseases.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine preparation and a preparation method for relieving cough, reducing inflammation, relieving asthma, and effectively treating various acute and chronic bronchitis, chronic obstructive pulmonary disease, upper respiratory tract infection and other diseases. Background technique [0002] Diseases such as bronchial asthma, upper respiratory tract infection and chronic obstructive pulmonary disease are common respiratory diseases that seriously endanger human health. According to statistics, the incidence of asthma in China has been increasing year by year in recent years. The prevalence rate of adults in my country is 1.5%. The incidence of asthma in children is now close to 2%, double that of 10 years ago. The prevalence rate of chronic bronchitis in the elderly over 50 years old in my country is as high as about 15%. And chronic obstructive ...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61K9/20A61K9/48A61K9/10A61K9/12A61K47/40A61K47/34A61P29/00A61P11/06A61P11/14A61P11/00A61K47/10A61K47/12A61K47/22
Inventor 周长新吴理茂李连达
Owner ZHEJIANG UNIV
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