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Medicine for treating intestinal obstruction of infants and preparation method thereof

A technology of intestinal obstruction and drugs, applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of treating the symptoms but not the root cause, affecting appetite, and having no targeted therapeutic drugs, etc., to achieve definite curative effect, The effect of short treatment course and no side effects

Inactive Publication Date: 2015-11-04
JINAN SHUNHAO BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0017] At present, there is no targeted drug for the treatment of intestinal obstruction, and it affects appetite.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0078] When the dosage form of the medicine is a granule, its preparation method may comprise the following steps:

[0079] The first step is to mix the various raw materials of the drug according to the stated ratio, add ethanol with an alcohol concentration of 4 to 8 times that of the mixture, and heat it to boiling and reflux for 3 to 5 hours, filter, and use osmotic Slowly percolate at a speed of 1-2ml per minute by roller method, collect the percolation liquid, then concentrate under reduced pressure at a vacuum of 0.06-0.09Mpa to a paste with a relative density of 1.04-1.10 at 50-60°C, and spray dry , the air inlet temperature of the spray dryer is 160-175°C, the outlet air temperature is 80-85°C, and then crushed into powder to make dry paste powder;

[0080] In the second step, 0.2-0.4 times of sucrose powder and 0.1-0.2 times of dextrin are added to the obtained dry paste powder to form granules, and dried at 40-50° C. to obtain granules.

[0081] When the dosage for...

Embodiment 1

[0089] Example 1 Granules

[0090] The preparation process of the granules of the present invention is as follows: get 150g of saffron seed, 210g of cicada wing vine, 320g of Baxiancao, 220g of Huosuoma, 140g of horizontal sutra mat, 300g of laurel leaf jasmine, 150g of purslane, 360g of hemp seed, 200g belly skin, 280g grass cistanche, 200g barley tiller, 400g Patrinia, 160g green bark, 180g Citrus aurantium, 200g tomb head, 330g tortoise shell, 20g Niu Xixi, 200g Banzhilian, 300g Huajindan, toxin removal Powder 180g, Smilax smilax 120g, Cassia 220g, Frankincense 150g, Red Cohosh 270g, Chixiaodou 160g, Angelica 310g, Radix Paeoniae Rubra 200g and Buckwheat 420g;

[0091] The first step is to mix the raw materials and medicinal materials of the medicine according to the stated ratio, add ethanol with an alcohol concentration of 7 times that of the mixture and be 90% ethanol, heat to boiling and reflux for 4 hours, filter, and use percolation method at 1.5ml per minute. Slowly...

Embodiment 2

[0093] Example 2 Capsules

[0094] The manufacture process of the capsule of the present invention is: get 200g of laurel seed, 190g of cicada wing vine, 270g of Baxian grass, 160g of fire soma, 180g of horizontal sutra mat, 250g of laurel leaf jasmine, 150g of purslane, 340g of hemp seed, Belly skin 140g, Herba Cistanche 260g, Wheat tiller 160g, Patrinia 360g, Green bark 240g, Fructus aurantium 280g, Mutouhui 150g, Tortoiseshell 300g, Niu Xixi 20g, Scutellaria barbata 140g, Huajindan 320g, poison removal Powder 220g, Smilax smilax 150g, Cassia 300g, Frankincense 150g, Red Cohosh 280g, Chixiaodou 220g, Angelica 280g, Radix Paeoniae Rubra 140g and Buckwheat 360g;

[0095] The first step is to mix the raw materials of the drug in proportion, add ethanol with an alcohol concentration of 95% that is 4 times the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration...

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Abstract

The invention discloses a medicine for treating intestinal obstruction of infants and a preparation method thereof. The medicine comprises the following raw herbal materials: Chinese buckeye seeds, securidaca inappendiculata, tender catchweed bedstraw, helicteres isora, calophyllum membranaceum, jasminum laurifolium, portulaca oleracea, fructus cannabis, pericarpium arecae, edible fat made from milk, vernonia andersonii, stephania longa, orobanche coerulescens, fruit of highland barley malt, ixeris denticulata, pericarpium citri reticulatae viride, fructus aurantii, patrinia heterophylla, eretmochelys imbricata, rumexpatientia, scutellaria barbata, crotalaria tetragona, sida szechuensis, tuber or root of smilax stans, semen cassia, olibanum, astilbe chinensis, breynia fruticosa, perilla fruit, vigna umbellata, angelica sinensis, euonymus phellomana, red peony root and buckwheat. The medicine has the benefits as follows: the medicine has the efficacy of regulating qi, removing stasis, activating blood, moistening the intestines and relieving dyspepsia, meanwhile, has the effects of clearing heat, cooling blood, guiding qi downwards, removing intestinal obstruction, and resisting infection, and has the advantages of quick action, high improvement rate, definite curative effect, short treatment course, no toxic or side effect, low cost and the like.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating intestinal obstruction in children and a preparation method thereof. Background technique [0002] Intestinal obstruction refers to the obstruction of the normal operation of intestinal contents, which is a common acute abdomen in pediatric surgery. Because it changes rapidly, early diagnosis and treatment are required. Delay in diagnosis and treatment can aggravate the development of the disease, and even serious situations such as intestinal necrosis, peritonitis, toxic shock, and death may occur. [0003] Intestinal or intestinal lesions that cause intestinal content to pass through obstacles are called intestinal obstruction. There are two types of causes of intestinal obstruction, one is called mechanical intestinal obstruction, mostly due to intestinal atresia, intestinal stricture, intestinal adhesion, intestinal tumor, intus...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K36/90A61P1/00A61K35/586
Inventor 杜国强颜瑞
Owner JINAN SHUNHAO BIOTECH CO LTD
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