The invention discloses a
fingerprint spectrum construction method of a
traditional Chinese medicine composition containing
salvia miltiorrhiza and
astragalus membranaceus. The construction method comprises the following steps: taking a
test solution and a reference solution of the
traditional Chinese medicine composition for detection; obtaining content information of a reference substance of the
traditional Chinese medicine composition according to a detection result; wherein the traditional Chinese
medicine composition comprises
salvia miltiorrhiza, radix polygonati
officinalis, caulis clematidis armandii,
ligusticum, liquorice, bighead atractylodes
rhizome, rhizoma smilacis glabrae, radix saposhnikoviae, radix rehmanniae recen,
radix ophiopogonis and
astragalus membranaceus, and the reference substances are
caffeic acid,
liquiritin,
rehmannia glutinosa libosch D, cimicifugin,
astilbin,
salvianolic acid B and
ammonium glycyrrhizinate. The detection method is simple, accurate, efficient, good in stability, high in precision, good in reproducibility, convenient and easy to master, energy can be effectively saved, the analysis cost is reduced, and the technical content is not disclosed in the prior art.