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Medicinal composition for treating intestinal obstruction and method for preparing the same

A technology of intestinal obstruction and composition, which is applied in the field of pharmaceutical compositions for the treatment of intestinal obstruction and the field of preparation thereof, can solve the problems of no preparations, inconvenient use, different side effects of patients and the like

Inactive Publication Date: 2008-01-30
广西壮族自治区药物研究所有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The above-mentioned published literature mainly involves the medical effect of treating adhesive intestinal obstruction with Dachengqi Decoction, a classical prescription of traditional Chinese medicine, and also mentions the use of compound Dachengqi Decoction for the treatment of adhesive intestinal obstruction. However, because some prescriptions also add some traditional Chinese medicines that cool blood or replenish blood, some patients have different side effects, and the adaptability is not wide.
And what present open document report is only hospital prescription, does not see to make preparation, uses inconvenient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0103] Rhubarb is crushed into coarse grains; citrus aurantium 222g, Magnolia officinalis 278g, peach kernel 222g, red peony root 278g, radish seed 556g, add 10 times of water to decoct twice, heat and decoct for 2 hours, filter, add 10 times of water to the dregs of the medicine for the last time When it boils, add 278g rhubarb coarse grains, heat and decoct for 1.5 hours, filter, combine the filtrate, concentrate to an appropriate volume, let it cool, add ethanol to make the alcohol content 60%, stir evenly, let stand, filter, The ethanol is recovered from the filtrate, concentrated into a thick paste, 75 g of Xuanming powder is added, mixed evenly, and then an appropriate amount of dextrin, sucrose powder and other commonly used auxiliary materials are added, mixed evenly, made into granules, dried to obtain granules.

Embodiment 2

[0105] Rhubarb is crushed into coarse grains; citrus aurantium 222g, Magnolia officinalis 278g, peach kernel 222g, red peony root 278g, radish seed 556g, add 10 times of water to decoct twice, heat and decoct for 2 hours, filter, add 10 times of water to the dregs of the medicine for the last time When it boils, add 278g rhubarb coarse grains, heat and decoct for 1.5 hours, filter, combine the filtrate, concentrate to an appropriate volume, let it cool, add ethanol to make the alcohol content 60%, stir evenly, let stand, filter, Recover ethanol from the filtrate and condense it into a thick paste, add 80g of xuanming powder, dry it, crush it into fine powder or make granules, and press it into tablets to get plain tablets; coat sugar-coated tablets on plain tablets to get sugar-coated tablets; Film-coated, film-coated tablets are obtained; enteric-coated tablets are coated on plain tablets, and enteric-coated tablets are obtained.

Embodiment 3

[0107] Rhubarb is crushed into coarse grains; citrus aurantium 222g, Magnolia officinalis 278g, peach kernel 222g, red peony root 278g, radish seed 556g, add 10 times of water to decoct twice, heat and decoct for 2 hours, filter, add 10 times of water to the dregs of the medicine for the last time When it boils, add 278g rhubarb coarse grains, heat and decoct for 1.5 hours, filter, combine the filtrate, concentrate to an appropriate volume, let it cool, add ethanol to make the alcohol content 60%, stir evenly, let stand, filter, Recover ethanol from the filtrate and concentrate it into a thick paste, add 85g of Xuanming powder, mix evenly, dry, pulverize into fine powder, pour water into pills, dry to get concentrated pills; add honey to make pills to get honeyed pills.

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Abstract

The present invention discloses a pharmaceutical composition for treating intestinal obstruction and the preparation method, which is composed of the active ingredients of 7 raw materials of rhubarb, officinal magnolia bark, immature bitter orange, matrii sulfas exsiccatus, red paeony root, peach seed and radish seed, the mix ratio by weight of all the raw materials are: 3.81 to 38.0 parts of rhubarb, 3.81 to 38.0 parts of officinal magnolia bark, 3.04 to 30.4 parts of immature bitter orange, 1.0 to 10.0 parts of matrii sulfas exsiccatus, 3.81 to 38.0 parts of red paeony root, 3.04 to 30.4 parts of peach seed and 7.61 to 76.1 parts of radish seed respectively. Compared with the prior art, the present invention is characterized by significant efficacy, easy administration, no side effects and moderate price; the present invention has the functions of dredging intestines, promoting qi and removing blood stasis, which is used for intestinal obstruction, and the prevention and treatment of abdominal postoperative tympanites and intestinal adhesion.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating intestinal obstruction and a preparation method thereof. technical background [0002] Intestinal obstruction is a common clinical acute abdomen. The patient is suffering and is in critical condition. Currently, there is no western medicine for the disease on the market. Western medicine generally adopts surgery. Flatulence, or intestinal adhesions, seriously affect the patient's recovery from surgery. Traditional Chinese medicine often uses the traditional Chinese medicine of Dachengqi Decoction. The Dachengqi Decoction is composed of four traditional Chinese medicines: rhubarb, magnolia, citrus and thenardite. Tang Jiawei" or Compound Dachengqi Soup. From the literature search, we also found the following relevant information, which are listed as follows: [0003] 1. 【Title】Therapeutic observation of 65 cases of adhesive intestinal obstruction treated with integrated traditional Ch...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61K9/00A61K9/14A61K9/16A61K9/20A61K9/48A61P1/00A61P41/00A61K33/04
Inventor 梁永平农小棉
Owner 广西壮族自治区药物研究所有限公司
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