78 results about "Oesophagram" patented technology

The invention discloses an esophageal endoscope image generation system and method based on an improved StyleGAN2-ADA network. The system comprises a generator and a discriminator. The generator comprises a mapping network and a synthesis network; the discriminator comprises a discrimination network, adopts an adaptive discriminator to enhance an ADA mechanism, and dynamically adjusts the image enhancement intensity according to the training accuracy of the discriminator; the method comprises the following steps: S1, fusing multi-vector features of a mapping network; s2, performing a multi-scale feature guided auxiliary classifier method on the discriminant network; s3, in the generative network, calculating a potential spatial distance loss and a comparison loss method; according to the method, the problems of non-uniform sample types and scarcity of data samples in medical images such as esophageal endoscopes are solved.

The invention discloses a digestive endoscopic esophageal trajectory optimization method based on Kalman filtering, and belongs to the technical field of digestive endoscopic surgical navigation, and the method comprises the following steps: S1, based on an esophageal model of preoperative CT three-dimensional reconstruction, extracting a geometric center point sequence of an esophageal cavity, generating an esophageal center line, and extracting a geometric center point sequence of the esophageal cavity; the method comprises the following steps of S1, acquiring six-degree-of-freedom pose data of the front end of an endoscope in real time through an electromagnetic positioning system, and generating an original motion track, and S3, performing rigid body registration on the original motion track and an esophagus center line by utilizing an iterative closest point (ICP) algorithm, so as to realize coordinate system coarse alignment. The real-time data of an electromagnetic positioning system and a three-dimensional model reconstructed by CT are combined, the navigation robustness is improved, the pose is adaptively corrected through Kalman filtering, the influence of environmental interference is reduced, the space relation between the endoscope and surrounding organs is visually displayed through an optimized track, and accurate operation of a doctor is assisted.

The invention provides a 4D printing esophageal stent and a preparation method thereof. The esophageal stent comprises a stent main body and a drug-loaded fiber membrane with a core-shell structure, the stent main body is a tubular stent composed of a bionic water lily hollow structure; the diameters of the head end and the tail end of the support body are larger than the diameter of the middle section, and barb structures are arranged on the outer surfaces of the head end and the tail end. The stent main body is a biodegradable shape memory polymer; the drug-loaded fibrous membrane is positioned on the outer surface of the middle section of the stent main body, and the drug-loaded fibrous membrane contains drugs. The 4D printing esophageal stent provided by the invention has excellent compressive bearing capacity and anti-slip capacity, and the drug-loaded fibrous membrane can avoid esophageal restenosis through long-term uniform slow release of drugs, so that the life safety of a patient can be further guaranteed.

A single unit oral dose pharmaceutical composition for use as a medicament for separate, sequential or simultaneous administration with an agonist of a 5-hydroxytryptamine (5-HT) receptor;wherein the single unit oral dose pharmaceutical composition comprises a first active ingredient and a second active ingredient;wherein the first active ingredient is for absorption in the gastrointestinal tract from the oesophagus onwards and the second active ingredient is for absorption in the oral cavity; andwherein the first active ingredient is naltrexone in an amount of 0.01 to 10 mg and the second active ingredient is calcitriol in an amount of 80 to 200 ug.

Systems and methods are disclosed for an endoscope for use in a surgical procedure, e.g., a pediatric trans-nasal endoscopy procedure. The endoscope may include a handle for gripping by a user, and a shaft extending from the handle. The shaft may have a working channel extending longitudinally therethrough. When the shaft is in a fully-inserted position, the shaft may have an extracorporeal zone configured to reside proximal relative to the patient's nasal opening, a patient comfort zone configured to reside from the patient's nose through the patient's pharynx and to a top of the patient's esophagus, and a distal functional endoscopic zone configured to reside from the top of the patient's esophagus to a distalmost tip of the shaft. The patient comfort zone has a relatively higher flexibility so as to maximize patient comfort for that portion of the shaft that is maintained in the curvatures of a patient's nasal cavity during a surgical procedure.

A system and method are provided for automatically detecting a two-dimensional standard view in a transesophageal ultrasound image. The method includes acquiring a first ultrasound image at a first depth and a first full-plane angle. The first ultrasound image corresponds to a first standard view. The first full-plane angle is an angle other than zero (0) degrees. The method includes adjusting the first full-plane angle to a second full-plane angle of 0 degrees. The method includes acquiring a second ultrasound image at the first depth and the second full-plane angle. The method includes automatically analyzing the second ultrasound image to identify a second standard view corresponding to the second full-plane angle. The method includes automatically determining the first standard view based on the second standard view and the first full-plane angle. The method includes causing a display system to display the first ultrasound image having a first identifier of the first standard view.

Apparatus and methods of determining a cardiac implant size and methods and system for transesophageal echocardiogram guided implantation of left atrial appendage closure device. The apparatus includes an ultrasonic imaging device, at least a processor, and a memory communicatively connected to the at least a processor, wherein the memory contains instructions configuring the at least a processor to using the ultrasonic imaging device collect a plurality of ultrasonic images using a 3D cardiac model generation machine learning model trained on a training dataset including example ultrasonic images correlated with example 3D cardiac models. The processor is further configured to generate a 3D cardiac model based on the plurality of ultrasonic images, generate at least a cardiac measurement based on the 3D cardiac model, determine a cardiac implant size based on the at least a cardiac measurement, and using a display, display to a user the cardiac implant size.

The present invention discloses an esophageal PH-electromyographic combined electrode catheter, comprising a tube body, a PH wire and a diaphragm wire, wherein the surface of the tube body is provided with two PH electrodes, a plurality of diaphragm electrical signal recording electrodes and a diaphragm electrical signal reference electrode; the two PH electrodes are respectively at the end and the middle of the tube body, the plurality of diaphragm electrical signal recording electrodes are all located between the two PH electrodes, and the diaphragm electrical signal reference electrode is located at the proximal end of the PH electrode in the middle; all the PH electrodes are connected to the PH wire in the tube body, and the signal output end of the PH wire is provided with a PH processor connector; the diaphragm electrical signal reference electrode and all the diaphragm electrical signal recording electrodes are connected to the diaphragm wire in the tube body, and the signal output end of the diaphragm wire is provided with an amplifier connector. The present invention can not only improve the accuracy of catheter positioning and simplify operation, but also reduce the patient's discomfort, and can also detect diaphragm function and help discover the cause of gastroesophageal reflux.

The invention relates to the technical field of esophageal ultrasound, in particular to an integrated esophageal ultrasound system which comprises an operation end, an insertion tube, a bent section, an end, an ultrasound module and an endoscope module. The insertion tube is mounted at the operating end, the bent section is mounted at one end, away from the operating end, of the insertion tube, and the tip is mounted at one end, away from the insertion tube, of the bent section. An ultrasonic probe of the ultrasonic module is installed on the side wall of the end. The lens end of the endoscope module is mounted on the front end wall of the tip. The device can effectively reduce discomfort and stress response of a patient in the esophageal ultrasound process, and is also suitable for the patient with local damage to the inner wall of the esophagus.

The invention relates to the technical field of medical treatment, and discloses a construction method of a left auricle hemodynamics simulation system, which comprises the following core steps of: firstly, acquiring noninvasive transthoracic echocardiography and cardiac enhancement CT (Computed Tomography) image data of a patient; secondly, through an image fusion technology, an accurate left auricle three-dimensional geometric structure model is constructed; and finally, on the basis of the model, carrying out hemodynamic simulation on the left atrium and the left auricle by utilizing a CFD (Computational Fluid Dynamics) technology, and accurately calculating hemodynamic parameters such as the blood flow velocity at the opening of the left auricle. The method has the advantages that the blood flow state of the left atrial appendage is evaluated completely, noninvasively, accurately and quantitatively, and traditional invasive transesophageal ultrasonic examination can be effectively replaced. According to the method, the comfort level of the patient and the examination safety are remarkably improved, operation related risks are avoided, meanwhile, the screening feasibility and efficiency are improved, and the method has important value for clinical management of the stroke risk of the atrial fibrillation patient.

The invention discloses a magnesium alloy esophageal stent capable of reducing implantation injury, and belongs to the technical field of metal additive manufacturing, the magnesium alloy esophageal stent comprises a fixed layer, a transition layer and a deformation layer, the two ends of the transition layer are connected with the fixed layer and the deformation layer respectively, the fixed layer is of a cylindrical fishing net structure formed by cross connection of 2N alloy wires in a first arrangement mode, the end, connected with the transition layer, of the fixing layer is the end, extending along the central axis, of the cylindrical fishing net-shaped structure of the fixing layer and stopping at the intersection of the fixing layer, and the transition layer is of an annular structure formed by sequentially connecting N / 2 alloy wire sets in a third arrangement mode. The alloy wire set comprises an axial wire and two inclined wires, the two inclined wires are located on the two sides of the axial wire respectively, sharp parts at the ends of a traditional stent under the condition cleaning condition are connected in an extending mode through the mode that the transition layer is arranged, the number of the sharp parts is reduced, and therefore the purpose of reducing esophageal injuries is achieved.

The application provides a method and system for estimating autonomous inspiration effort intensity based on a respiratory system model under pressure control ventilation, which simulates airway pressure waveform data assuming no autonomous inspiration effort by combining airway pressure waveform data existing autonomous inspiration effort under pressure control ventilation with autonomous breathing lung ventilation model, obtains airway resistance and respiratory system compliance to obtain flow waveform according to respiratory mechanics motion equation by using original waveform data measured clinically, and then carries out error analysis with flow waveform existing autonomous inspiration effort measured clinically, finally estimates autonomous inspiration effort intensity by using linear regression curve fitting obtained from error index value of flow waveform data assuming no autonomous inspiration effort and flow waveform data existing autonomous inspiration effort obtained from a number of known gold standard esophageal pressure deviation patients, and realizes autonomous inspiration effort intensity estimation without esophageal pressure.

The application relates to the technical field of ultrasonic probe protection devices, and provides a transesophageal ultrasonic probe protection sleeve, which comprises a bite sleeve, a protection sleeve and an elastic constriction ring, a probe hole is arranged through the bite sleeve, the protection sleeve is coaxially arranged in the probe hole, the protection sleeve has opposite open ends and a closed end, the open end is connected with the bite sleeve, the elastic constriction ring is sleeved on the protection sleeve, and the protection sleeve is constrained by the elastic constriction ring to form a sealed coupling agent cavity for accommodating the coupling agent. The utility model discloses the closed end of the protection sleeve is formed into a sealed coupling agent cavity by arranging the elastic constriction ring sleeve on the protection sleeve, the coupling agent cavity can be pre-filled with the coupling agent before use or in production, pollution caused by manual smearing can be avoided during use, the elastic constriction ring is stretched by being extruded by the probe when the protection sleeve is sleeved, the probe can be inserted into the elastic constriction ring at the moment, a sealed cavity is formed between the probe and the closed end of the protection sleeve, the coupling agent is difficult to disperse, and the image acquisition quality is improved.

Stoma interface devices and methods for manufacturing the same for total laryngectomy and select partial laryngectomy patients that fit directly into the tracheostoma where the devices provide a support which can interface with standardized tracheostoma components (e.g., speaking valves) and offer hands-free alternatives for tracheoesophageal (TE) speech production. Devices hereof comprise a body having a self-expanding frame coated in multi-durometer silicone elastomers to form a distal portion with a distal flange configured to engage the tracheostoma of the patient, and a proximal portion configured to interface with the tracheostoma components.

A system for a bypass-like, transduodenal passage of stomach contents, comprising: a transduodenal bypass unit (BE), itself comprising a transduodenal assembly (TDG) having a tubular film (7) for the passage of stomach contents into the jejunum, and also comprising a transpyloric assembly (TPG) having a hose-like or tubular shaft component (2); a transesophageal positioning unit (PE) having a tubular shaft component (9), the outer diameter of said shaft component being smaller, at least in a distal region, than the inner diameter of the shaft component (2); and an extracorporeally controllable coupling device (KE) which selectively fixates the shaft component (2) to the shaft component (9) for coupling purposes or releases the same for decoupling purposes.

A system and method for transesophageal echocardiogram-guided implantation of a stent are disclosed. The system includes at least a transesophageal echocardiogram (TEE) system, at least a display and at least a computing device configured to receive a plurality of ultrasound images, generate at least a three-dimensional (3D) cardiac model as a function of the plurality of ultrasound images, receive at least a 3D stent model, determine a view label for each of the plurality of ultrasound images and display the at least a 3D cardiac model and the at least a 3D stent model as a function of the view label.

This design is a medical tube holder that includes a cylindrical tube holding portion with a U-shaped notch that can hold a medical tube, and a throat pad with long holes on both the left and right ends in a plan view for passing a band through. When fixing a tube placed by percutaneous transesophageal gastric tube placement to a patient's neck, the tube is held in place by the tube holding portion, and the back side of the tube is placed against the patient's skin. Bands are passed through the long holes on both the left and right ends of the throat pad to fix the medical tube placed in the patient's body.

The present invention discloses a photoacoustic capsule endoscope and an imaging method. The photoacoustic capsule endoscope includes an optical path folding component, an optical collimating and focusing component, a miniaturized internal scanning component, a port connection component, and a multi-angle imaging probe. The multi-angle imaging probe can be quickly and conveniently replaced through the port connection component to adapt to different types of internal cavities or cavity walls such as the esophagus, rectum, and cervix. By designing the internal structure of the imaging probe and introducing new devices, the device can achieve a miniaturized size of 5mm in diameter and 15mm in hard length, meeting the needs of high-degree-of-freedom, rapid, and non-destructive imaging in the body, expanding the detectable area and imaging depth, avoiding the influence of motion artifacts and image distortion, reducing clinical use costs, and realizing multi-angle full-space endoscopic imaging.

The invention provides a method for screening left atrial appendage thrombus by using a multi-mode ultrasonic technology, and relates to the technical field of medical ultrasonic diagnosis. According to the method for screening the left atrial appendage thrombus by using the multi-mode ultrasonic technology, through a layered screening process of noninvasive primary screening, precise secondary screening and comprehensive judgment, the technical advantages of four complementary modes of transthoracic ultrasound (TTE), transesophageal ultrasound (TEE), ultrasonic contrast (CEUS) and shear wave elastography (SWE) are integrated, primary risk stratification is completed by using noninvasive TTE, and secondary risk stratification is completed by using noninvasive TTE; tEE is combined with CEUS and SWE to achieve multi-dimensional evaluation of the structure, the blood flow and the hardness of the thrombus for high-risk groups, and finally accurate detection and stability evaluation of the thrombus are achieved based on the judgment standard of multi-modal data fusion. According to the method, the detection rate of the left auricle thrombus can be remarkably increased, the unnecessary invasive operation risk is reduced, meanwhile, thrombus stability basis is provided for formulating a clinical anticoagulation treatment scheme, and the method is suitable for conventional screening of thrombus high-risk groups such as atrial fibrillation and the like.

A method (200) for assessing reliability of a cardiac parameter of a subject is disclosed. The method comprises receiving data (201) from a transesophageal echocardiography probe, a heart activity sensor, and a motion sensor, determining (202) a TEE cardiac parameter relating to the cardiac parameter estimated using data from the transesophageal echocardiography probe, determining a heart activity cardiac parameter relating to the cardiac parameter estimated using data from the heart activity sensor, determining (203) the cardiac parameter based on at least one of the TEE and heart activity parameters, assessing the reliability of the cardiac parameter based on the TEE and heart activity parameters and the data from the motion sensor, and transmitting to an output device, a feedback signal based on the reliability of the cardiac parameter. In accordance with the invention, the method further comprises determining (206) a cardiac parameter trend and whether the cardiac parameter trend exceeds a trend threshold, detecting motion of the subject (220) during a first time period, based on the data of the motion sensor, and assessing the reliability of the cardiac parameter based on whether the cardiac parameter trend exceeds the trend threshold and on whether motion of the subject has been detected. Also disclosed are a computer program and a system (3) for implementing such a method.

The utility model provides a medical transport case for transesophageal ultrasonic probes, which relates to the field of medical supplies and comprises an upper case body, a lower case body, a push spring, a support rod and a fixing bolt. A preoperative esophageal ultrasonic probe storage box is placed on the upper side surface of the upper box body; a postoperative esophageal ultrasonic probe storage box is placed on the upper side face of the lower box body, a sealing plate is hinged to the lower side face of the lower box body, and the front side face of the sealing plate is connected with a pressing plate through a fixing bolt; the outer side face of the supporting rod is slidably connected with a clamping block. A clamping block is welded to the rear end of the pushing and pressing spring. Through the arrangement of a clamping block, a sealing plate, a pressing plate, a preoperative esophageal ultrasonic probe storage box and a postoperative esophageal ultrasonic probe storage box, the preoperative esophageal ultrasonic probe and the postoperative esophageal ultrasonic probe are fixedly placed in the transportation box in an isolated mode, and medical staff can conveniently detach and clean the transportation box; the problems that a traditional esophageal ultrasonic probe transport case is prone to collision and damage in the case, and the case body is prone to pollution and difficult to clean are solved.

The invention relates to a construction method and application of homologous mouse esophageal squamous carcinoma 3D (three-dimensional) organoids, and the construction method comprises the following specific steps: S1, inducing homologous mice to spontaneously form esophageal squamous carcinoma in situ by using a chemical carcinogen, and constructing a primary mouse esophageal squamous carcinoma model to obtain mouse esophageal squamous carcinoma tumor tissues; and S2, dissociating the mouse esophageal squamous cell carcinoma tumor tissue obtained in the step S1 into single cells, inoculating the single cells into an esophageal squamous cell carcinoma 3D organ amplification culture medium, and carrying out 3D culture to obtain the homologous mouse esophageal squamous cell carcinoma 3D organ. Compared with the prior art, the homologous mouse esophageal squamous cell carcinoma 3D organoid provided by the invention can realize stable proliferation and continuous passage, has very strong similarity with the structure and molecular biological characteristics of an in-situ tumor, and can better simulate the growth condition of the tumor in an in-vivo three-dimensional environment; a powerful experimental tool and a model platform are provided for research on the formation mechanism of the esophageal squamous cell carcinoma, targeted drug development and immunotherapy research.

A system for transesophageal echocardiogram-guided implantation of a valve device, the system including at least a transesophageal echocardiogram system configured to detect at least an ultrasound image and at least a computing device configured to receive at least an ultrasound image, generate at least a 3D cardiac model representative of a heart of the patient as a function of at least an ultrasound image wherein the at least an ultrasound image includes a two-dimensional image of the heart of the patient and wherein the 3D cardiac model includes a three dimensional interpolation of the two-dimensional image, determine a valve model datum as a function of the 3D cardiac model, receive at least valve model representative of at least a cardiovascular device to be placed within the patient as a function of the valve model datum and display the at least a 3D cardiac model and at least a valve model.

The following generally relates to systems and methods for automating transesophageal echocardiography (TEE). Some aspects relate to a TEE probe having an ultrasound transducer at its distal end. In some embodiments, if the target is within the field of view (FOV) of the ultrasound transducer, the electron beam directional adjustment of the probe is adjusted; if the target is at the edge of the FOV, both the electron beam directional adjustment and the mechanical joints of the probe are adjusted; and if the target is not within the FOV, only the mechanical joints of the probe are adjusted.

The present invention discloses a gastric gavage device for animals specifically for administering Chinese medicine pills, comprising a gastric gavage head, a connecting tube, and a syringe device. The connecting tube is made of a hard material, the gastric gavage head is in the shape of a hemispherical shell and has a through hole at its top. The inner cavity of the gastric gavage head communicates with the inner cavity of the connecting tube through the through hole, and the gastric gavage head is fixedly connected to one end of the connecting tube. The syringe device comprises a push rod and a syringe, the other end of the connecting tube is sleeved with the injection end of the syringe, and the inner cavity of the connecting tube communicates with the inner cavity of the syringe. The device also comprises a gastric gavage pusher head, the gastric gavage pusher head is located inside the gastric gavage head housing, and is fixedly connected to one end of the pusher head located inside the syringe via a connecting rod, the connecting rod passing through the through hole and the inner cavity of the connecting tube in sequence. The present invention has a simple structure and strong practicality. While improving the efficiency of gastric gavage of Chinese medicine pills for animals and reducing damage to the animal's esophagus, it can also restore the process of patients taking pills in solid form and then digesting and absorbing them in the body.

The invention discloses a multiplex PCR (Polymerase Chain Reaction) detection primer group for sheep alimentary canal nematode eggs, a kit and application, and relates to the technical field of molecular detection. The primer group comprises the following three pairs of primers: a haemonchus contortus detection primer, an oesophagus nematode detection primer and a hair head nematode detection primer. The multiplex PCR detection kit comprises the primer group, ultrapure water (ddH2O) and 2 * Rapid Taq Master Mix, wherein the primer group is used for detecting the three pairs of multiplex PCR detection primers, and the ultrapure water (ddH2O) and the 2 * Rapid Taq Master Mix are used. The multiplex PCR detection kit and the detection method have the beneficial effects that the multiplex PCR detection kit and the detection method which can be used for simultaneously detecting eggs of haemonchus contortus, oesophagus nematode and hair head nematode are established, and the multiplex PCR detection kit and the detection method have the characteristics of economy, rapidness, high efficiency, strong specificity and good repeatability and can be applied to rapid detection of infection conditions of main digestive tract nematodes of sheep.

The probe oral pad assembly for the transesophageal echocardiography comprises an oral pad and a rubber sleeve, the oral pad comprises an oral pad body and a baffle, the baffle is of an edge structure formed by extending the oral pad body outwards, the oral pad body is divided into an esophagus stretching-in section and an external connecting section through the baffle, and the rubber sleeve is connected with the esophagus stretching-in section. The end, away from the baffle, of the external connection section is provided with a flange structure, the rubber sleeve is of an elastic flexible rubber sleeve structure, the external connection section is sleeved with one end of the rubber sleeve, and the probe is sleeved with the other end of the rubber sleeve. The probe oral pad assembly for transesophageal echocardiography can seal necessary gaps to assist in detection.

The invention relates to an intelligent intervention system for preventing aspiration in cerebral apoplexy, which belongs to the technical field of medical instruments and comprises a throat fixing and supporting structure, a swallowing power propulsion device, a negative pressure protection module and a central control unit. All the modules form a closed-loop control system through mechanical linkage and data interaction, the fixed supporting structure adopts a memory material framework capable of fitting the physiological curve of the neck, and a flexible myoelectricity sensing network is integrated to collect swallowing muscle group electric signals in real time; the swallowing propelling device realizes dynamic angle adjustment of an esophageal catheter through pneumatic driving, and cooperates with an inner wall structure to enhance the food mass pushing efficiency; the central control unit analyzes electromyographic signals and catheter deformation data through an intelligent algorithm, and synchronously regulates and controls power output and negative pressure intensity. By means of the system, the aspiration risk can be recognized in real time, the reflux path is blocked through cooperative intervention of mechanical propulsion and negative pressure protection, intelligent safety protection in the swallowing process is achieved, and the feeding safety and rehabilitation comfort of a stroke patient are effectively improved.

A medical information processing device of an embodiment includes processing circuitry. The processing circuitry is configured to acquire a CT image of a chest of a subject, acquires an esophageal pressure and an airway pressure of the subject, generate a risk information map in a lung field of the subject on a basis of the CT image, the esophageal pressure, and the airway pressure, estimate risk information in the lung field of the subject on a basis of the risk information map, and display the risk information map and the risk information on a display.

This invention discloses an esophageal cancer lesion image assessment system, comprising a basic image processing module for generating initial lesion area focus data from input esophageal images; a doctor interaction acquisition module for collecting doctor's correction operations on the initial lesion area focus data; a preference learning module for learning individual preference parameters corresponding to the doctor based on the correction operations; and a personalized output module for calibrating the initial lesion area focus data based on the individual preference parameters and outputting personalized lesion area focus data. This esophageal cancer lesion image assessment system improves the assessment process for esophageal cancer lesions, reducing repetitive correction operations for doctors in handling consecutive cases, decreasing the additional workload as the number of cases increases, and making the initial output more aligned with the doctor's interpretation methods, thereby improving the overall efficiency of the assessment task.