104 results about "Oesophagram" patented technology

An apparatus for transesophageal echo-oximetry, including: an insertion tube having an optical fiber disposed therein: a probe disposed at an end of the insertion tube, the probe including: an acoustic transducer, and a reflector aligned with the acoustic transducer and the optical fiber: a controller in communication with the acoustic transducer. the controller configured to: generate an ultrasonic image of a sample using the acoustic transducer and the reflector, direct light from the optical fiber toward the reflector and into the sample, collect photoacoustic signals from the sample based on the directed light using the acoustic transducer and the reflector, and determine a blood oxygenation level in the sample based on the photoacoustic signals.

The invention discloses an esophageal endoscope image generation system and method based on an improved StyleGAN2-ADA network. The system comprises a generator and a discriminator. The generator comprises a mapping network and a synthesis network; the discriminator comprises a discrimination network, adopts an adaptive discriminator to enhance an ADA mechanism, and dynamically adjusts the image enhancement intensity according to the training accuracy of the discriminator; the method comprises the following steps: S1, fusing multi-vector features of a mapping network; s2, performing a multi-scale feature guided auxiliary classifier method on the discriminant network; s3, in the generative network, calculating a potential spatial distance loss and a comparison loss method; according to the method, the problems of non-uniform sample types and scarcity of data samples in medical images such as esophageal endoscopes are solved.

The invention discloses a digestive endoscopic esophageal trajectory optimization method based on Kalman filtering, and belongs to the technical field of digestive endoscopic surgical navigation, and the method comprises the following steps: S1, based on an esophageal model of preoperative CT three-dimensional reconstruction, extracting a geometric center point sequence of an esophageal cavity, generating an esophageal center line, and extracting a geometric center point sequence of the esophageal cavity; the method comprises the following steps of S1, acquiring six-degree-of-freedom pose data of the front end of an endoscope in real time through an electromagnetic positioning system, and generating an original motion track, and S3, performing rigid body registration on the original motion track and an esophagus center line by utilizing an iterative closest point (ICP) algorithm, so as to realize coordinate system coarse alignment. The real-time data of an electromagnetic positioning system and a three-dimensional model reconstructed by CT are combined, the navigation robustness is improved, the pose is adaptively corrected through Kalman filtering, the influence of environmental interference is reduced, the space relation between the endoscope and surrounding organs is visually displayed through an optimized track, and accurate operation of a doctor is assisted.

The invention provides a 4D printing esophageal stent and a preparation method thereof. The esophageal stent comprises a stent main body and a drug-loaded fiber membrane with a core-shell structure, the stent main body is a tubular stent composed of a bionic water lily hollow structure; the diameters of the head end and the tail end of the support body are larger than the diameter of the middle section, and barb structures are arranged on the outer surfaces of the head end and the tail end. The stent main body is a biodegradable shape memory polymer; the drug-loaded fibrous membrane is positioned on the outer surface of the middle section of the stent main body, and the drug-loaded fibrous membrane contains drugs. The 4D printing esophageal stent provided by the invention has excellent compressive bearing capacity and anti-slip capacity, and the drug-loaded fibrous membrane can avoid esophageal restenosis through long-term uniform slow release of drugs, so that the life safety of a patient can be further guaranteed.

The invention provides an esophageal pressure signal filtering method and an esophageal pressure filtering device. The method comprises the following steps: acquiring an esophageal pressure signal of a patient; constructing a reference signal according to the esophageal pressure signal; updating filtering parameters of an adaptive filter according to the reference signal to obtain an updated adaptive filter; and filtering a heartbeat incisura signal in the esophageal pressure signal according to the updated adaptive filter. According to the filtering method for the esophageal pressure signal, the noise signal in the esophageal pressure signal can be effectively filtered out.

A single unit oral dose pharmaceutical composition for use as a medicament for separate, sequential or simultaneous administration with an agonist of a 5-hydroxytryptamine (5-HT) receptor;wherein the single unit oral dose pharmaceutical composition comprises a first active ingredient and a second active ingredient;wherein the first active ingredient is for absorption in the gastrointestinal tract from the oesophagus onwards and the second active ingredient is for absorption in the oral cavity; andwherein the first active ingredient is naltrexone in an amount of 0.01 to 10 mg and the second active ingredient is calcitriol in an amount of 80 to 200 ug.

The utility model provides a multifunctional mouth bite, which comprises a mouth bite body provided with an operation port along a long axis, and is characterized in that the mouth bite body is provided with an oxygen inhalation cavity or / and an exhaled air collection cavity at the side of the operation port along the long axis in a penetrating manner, and the tail part of the exhaled air collection cavity is provided with a carbon dioxide monitoring interface. The device is used for ordinary and painless gastroscope operations, oxygen inhalation and end-tidal carbon dioxide monitoring; the fixing device is used for TEE (transesophageal cardiac ultrasonography) examination under general anesthesia, a tracheal catheter and a TEE probe can be conveniently fixed, and the fixing device is simple in structure, low in cost, safe and reliable.

Systems and methods are disclosed for an endoscope for use in a surgical procedure, e.g., a pediatric trans-nasal endoscopy procedure. The endoscope may include a handle for gripping by a user, and a shaft extending from the handle. The shaft may have a working channel extending longitudinally therethrough. When the shaft is in a fully-inserted position, the shaft may have an extracorporeal zone configured to reside proximal relative to the patient's nasal opening, a patient comfort zone configured to reside from the patient's nose through the patient's pharynx and to a top of the patient's esophagus, and a distal functional endoscopic zone configured to reside from the top of the patient's esophagus to a distalmost tip of the shaft. The patient comfort zone has a relatively higher flexibility so as to maximize patient comfort for that portion of the shaft that is maintained in the curvatures of a patient's nasal cavity during a surgical procedure.

A system and method are provided for automatically detecting a two-dimensional standard view in a transesophageal ultrasound image. The method includes acquiring a first ultrasound image at a first depth and a first full-plane angle. The first ultrasound image corresponds to a first standard view. The first full-plane angle is an angle other than zero (0) degrees. The method includes adjusting the first full-plane angle to a second full-plane angle of 0 degrees. The method includes acquiring a second ultrasound image at the first depth and the second full-plane angle. The method includes automatically analyzing the second ultrasound image to identify a second standard view corresponding to the second full-plane angle. The method includes automatically determining the first standard view based on the second standard view and the first full-plane angle. The method includes causing a display system to display the first ultrasound image having a first identifier of the first standard view.

Apparatus and methods of determining a cardiac implant size and methods and system for transesophageal echocardiogram guided implantation of left atrial appendage closure device. The apparatus includes an ultrasonic imaging device, at least a processor, and a memory communicatively connected to the at least a processor, wherein the memory contains instructions configuring the at least a processor to using the ultrasonic imaging device collect a plurality of ultrasonic images using a 3D cardiac model generation machine learning model trained on a training dataset including example ultrasonic images correlated with example 3D cardiac models. The processor is further configured to generate a 3D cardiac model based on the plurality of ultrasonic images, generate at least a cardiac measurement based on the 3D cardiac model, determine a cardiac implant size based on the at least a cardiac measurement, and using a display, display to a user the cardiac implant size.

In one aspect, a nasal transluminal feeding catheter (1) according to the present disclosure comprises a tube (40) and a connector (10) that is provided at one end of the tube (40). The tube (40) includes a plurality of protrusions (41) that are formed integrally with an inner circumferential surface of the tube (40) and that extend along the lengthwise direction of the tube (40). Each protrusion (41) faces a portion (42) of the tube (40) in which protrusions (41) are not formed. A cross-section of the tube (40) can be deformed to be flat when the portion (42) of the tube (40) in which protrusions (41) are not formed is bent by pharyngeal pressure or intraesophageal pressure. The thickness of the portion (42) of the tube (40) in which protrusions (41) are not formed is preferably not more than 0.6 mm.

The invention provides a simple frame for an ultrasonic probe handle, belongs to the technical field of medical equipment, and solves the technical problem of placement of the ultrasonic probe handle. A simple frame for a transesophageal ultrasonic probe handle comprises a stand column and a second supporting arm, the bottom of the stand column is fixedly connected with a base, the surface of the stand column is vertically and slidably connected with a first supporting arm, a sliding mechanism for sliding the first supporting arm is arranged in the stand column, and the second supporting arm is slidably arranged in the first supporting arm in a sleeved mode. A limiting mechanism for limiting sliding of the second supporting arm is arranged in the first supporting arm, a third supporting arm is hinged to the end, away from the first supporting arm, of the second supporting arm, and a mounting mechanism is arranged at one end of the third supporting arm. According to the device, through the arrangement of the first supporting arm, the first supporting arm can slide up and down according to the height in the using process, meanwhile, in the process that the first supporting arm slides up and down according to the height, the supporting frame and the two rolling wheels can slide, and the device is more stable to use.

The present invention discloses an esophageal PH-electromyographic combined electrode catheter, comprising a tube body, a PH wire and a diaphragm wire, wherein the surface of the tube body is provided with two PH electrodes, a plurality of diaphragm electrical signal recording electrodes and a diaphragm electrical signal reference electrode; the two PH electrodes are respectively at the end and the middle of the tube body, the plurality of diaphragm electrical signal recording electrodes are all located between the two PH electrodes, and the diaphragm electrical signal reference electrode is located at the proximal end of the PH electrode in the middle; all the PH electrodes are connected to the PH wire in the tube body, and the signal output end of the PH wire is provided with a PH processor connector; the diaphragm electrical signal reference electrode and all the diaphragm electrical signal recording electrodes are connected to the diaphragm wire in the tube body, and the signal output end of the diaphragm wire is provided with an amplifier connector. The present invention can not only improve the accuracy of catheter positioning and simplify operation, but also reduce the patient's discomfort, and can also detect diaphragm function and help discover the cause of gastroesophageal reflux.

The invention relates to the technical field of esophageal ultrasound, in particular to an integrated esophageal ultrasound system which comprises an operation end, an insertion tube, a bent section, an end, an ultrasound module and an endoscope module. The insertion tube is mounted at the operating end, the bent section is mounted at one end, away from the operating end, of the insertion tube, and the tip is mounted at one end, away from the insertion tube, of the bent section. An ultrasonic probe of the ultrasonic module is installed on the side wall of the end. The lens end of the endoscope module is mounted on the front end wall of the tip. The device can effectively reduce discomfort and stress response of a patient in the esophageal ultrasound process, and is also suitable for the patient with local damage to the inner wall of the esophagus.

The disposable esophageal stent system comprises an implantation device and a stent, the implantation device comprises an outer sheath tube, one end of the outer sheath tube is fixedly connected with a handle, a controller with a display screen is arranged on the side wall of the handle, a middle tube penetrates through the outer sheath tube, and the stent is arranged in the middle tube. One end of the middle tube penetrates through the side wall of the handle and is fixedly connected with a push rod, the other end of the middle tube is fixedly connected with a guide head, the guide head is located at one end of the outer sheath tube, the support is compressed and installed in the outer sheath tube, the middle tube is fixedly connected with a push plug, the push plug abuts against the side wall of one end of the support, and the push rod is fixedly connected with the push rod. The side wall of the support is fixedly connected with a linear permanent magnet film strip. In the process of releasing the stent, the stent is axially rotated and adjusted in time, so that the esophageal stent can be stably released along a straight line, twisting displacement of the stent is avoided, and safety and accuracy of stent surgery are improved.

The invention relates to the technical field of medical treatment, and discloses a construction method of a left auricle hemodynamics simulation system, which comprises the following core steps of: firstly, acquiring noninvasive transthoracic echocardiography and cardiac enhancement CT (Computed Tomography) image data of a patient; secondly, through an image fusion technology, an accurate left auricle three-dimensional geometric structure model is constructed; and finally, on the basis of the model, carrying out hemodynamic simulation on the left atrium and the left auricle by utilizing a CFD (Computational Fluid Dynamics) technology, and accurately calculating hemodynamic parameters such as the blood flow velocity at the opening of the left auricle. The method has the advantages that the blood flow state of the left atrial appendage is evaluated completely, noninvasively, accurately and quantitatively, and traditional invasive transesophageal ultrasonic examination can be effectively replaced. According to the method, the comfort level of the patient and the examination safety are remarkably improved, operation related risks are avoided, meanwhile, the screening feasibility and efficiency are improved, and the method has important value for clinical management of the stroke risk of the atrial fibrillation patient.

The utility model discloses an esophageal ultrasonic probe fixing frame, which relates to the technical field of medical instruments, and comprises a main body fixing mechanism, a support rod, a fixing mechanism and a fixing mechanism, and is characterized in that the main body fixing mechanism is arranged at the lower end of the support rod; the supporting rod is rotationally arranged at the upper end of the main body fixing mechanism and is of a telescopic rod structure; the support is arranged at the upper end of the supporting rod in a transferring mode, and a probe positioning mechanism is arranged on the support and matched with the esophageal ultrasonic probe. When in use, the fixing frame is fixed on a bed body, and the position does not need to be repeatedly adjusted; by using the fixing frame, the esophageal ultrasonic probe can be quickly positioned, repeated adjustment is not needed, the operation time is greatly shortened, and the diagnosis and treatment efficiency is improved; meanwhile, repeated stimulation to the esophagus of the patient is reduced through stable positioning of the probe, and the comfort degree of the patient in the diagnosis and treatment process is improved; the problems that an existing esophageal ultrasonic probe is difficult to effectively fix and tedious to adjust during clinical use are solved.

The invention discloses a magnesium alloy esophageal stent capable of reducing implantation injury, and belongs to the technical field of metal additive manufacturing, the magnesium alloy esophageal stent comprises a fixed layer, a transition layer and a deformation layer, the two ends of the transition layer are connected with the fixed layer and the deformation layer respectively, the fixed layer is of a cylindrical fishing net structure formed by cross connection of 2N alloy wires in a first arrangement mode, the end, connected with the transition layer, of the fixing layer is the end, extending along the central axis, of the cylindrical fishing net-shaped structure of the fixing layer and stopping at the intersection of the fixing layer, and the transition layer is of an annular structure formed by sequentially connecting N / 2 alloy wire sets in a third arrangement mode. The alloy wire set comprises an axial wire and two inclined wires, the two inclined wires are located on the two sides of the axial wire respectively, sharp parts at the ends of a traditional stent under the condition cleaning condition are connected in an extending mode through the mode that the transition layer is arranged, the number of the sharp parts is reduced, and therefore the purpose of reducing esophageal injuries is achieved.

The application provides a method and system for estimating autonomous inspiration effort intensity based on a respiratory system model under pressure control ventilation, which simulates airway pressure waveform data assuming no autonomous inspiration effort by combining airway pressure waveform data existing autonomous inspiration effort under pressure control ventilation with autonomous breathing lung ventilation model, obtains airway resistance and respiratory system compliance to obtain flow waveform according to respiratory mechanics motion equation by using original waveform data measured clinically, and then carries out error analysis with flow waveform existing autonomous inspiration effort measured clinically, finally estimates autonomous inspiration effort intensity by using linear regression curve fitting obtained from error index value of flow waveform data assuming no autonomous inspiration effort and flow waveform data existing autonomous inspiration effort obtained from a number of known gold standard esophageal pressure deviation patients, and realizes autonomous inspiration effort intensity estimation without esophageal pressure.

The invention discloses a shape memory esophageal stent with an anti-displacement function and a preparation method of the shape memory esophageal stent. The shape memory esophageal stent is of a double-layer structure and comprises a supporting layer and a tissue adhesion functional layer. The supporting layer is constructed by a functional polylactic acid skeleton subjected to catechol-metal ion coordination crosslinking, and the tissue adhesion functional layer is constructed by covalently crosslinked polyethylene glycol diacrylate, dopamine methacrylamide and double-bond modified silk fibroin. The supporting layer and the tissue adhesion functional layer are connected through catechol-metal ion coordination. The esophageal stent disclosed by the invention is simple to prepare, has excellent biological tissue adhesion and body fluid response shape memory characteristics, has the characteristic of self-expansion in a human body environment and anti-displacement capability during application, and shows a relatively high application prospect.

The invention relates to the technical field of medical equipment, and discloses a nasal gastrointestinal catheter imaging imbedding system which comprises a control table, the control table is connected with a navigation module, the control table is used for controlling the system, and the navigation module is used for providing real-time navigation information and assisting a doctor or an operator in guiding a catheter or a tool to a needed position. The navigation module is connected with the endoscopic device, the endoscopic device is used for capturing internal images of the esophagus, the stomach or the intestinal tract of a patient, the console is connected with the imaging control module, the imaging control module is used for controlling the images of the endoscopic device, and the console is connected with the remote operation module. Through the network stabilization module, the network stability of the remote operation module in the nasal gastrointestinal catheter imaging imbedding system can be enhanced, so that an expert doctor can obtain enough information to carry out accurate diagnosis, the treatment progress of a patient cannot be delayed, and the pain of the patient is reduced.

The invention discloses a transesophageal visual intelligent ultrasonic probe, and belongs to the technical field of medical instrument image processing. The combination of the sliding rail, the sliding block and the locking switch is adopted, the supporting plate can freely slide and be stably locked, different operation requirements are met, it is guaranteed that the probe is stable, rapid fixing can be achieved when the probe is not used, the burden of medical staff is relieved, the ultrasonic image and the physiological parameters of a patient are combined, and the ultrasonic image and the physiological parameters of the patient are combined through feature matching, data association and fusion calculation. A cross-modal intelligent analysis system is established, the limitation of single ultrasonic image diagnosis is broken through, more accurate lesion recognition and diagnosis support is provided, accurate segmentation and feature extraction are performed on a lesion area through deep learning, lesion details are enhanced through histogram equalization, meanwhile, a lesion contour is automatically drawn, a disease type and related information are marked, and the accuracy of lesion recognition and diagnosis is improved. The ultrasonic image is more visual, and the diagnosis efficiency and accuracy of doctors are improved.

The application relates to the technical field of ultrasonic probe protection devices, and provides a transesophageal ultrasonic probe protection sleeve, which comprises a bite sleeve, a protection sleeve and an elastic constriction ring, a probe hole is arranged through the bite sleeve, the protection sleeve is coaxially arranged in the probe hole, the protection sleeve has opposite open ends and a closed end, the open end is connected with the bite sleeve, the elastic constriction ring is sleeved on the protection sleeve, and the protection sleeve is constrained by the elastic constriction ring to form a sealed coupling agent cavity for accommodating the coupling agent. The utility model discloses the closed end of the protection sleeve is formed into a sealed coupling agent cavity by arranging the elastic constriction ring sleeve on the protection sleeve, the coupling agent cavity can be pre-filled with the coupling agent before use or in production, pollution caused by manual smearing can be avoided during use, the elastic constriction ring is stretched by being extruded by the probe when the protection sleeve is sleeved, the probe can be inserted into the elastic constriction ring at the moment, a sealed cavity is formed between the probe and the closed end of the protection sleeve, the coupling agent is difficult to disperse, and the image acquisition quality is improved.

Stoma interface devices and methods for manufacturing the same for total laryngectomy and select partial laryngectomy patients that fit directly into the tracheostoma where the devices provide a support which can interface with standardized tracheostoma components (e.g., speaking valves) and offer hands-free alternatives for tracheoesophageal (TE) speech production. Devices hereof comprise a body having a self-expanding frame coated in multi-durometer silicone elastomers to form a distal portion with a distal flange configured to engage the tracheostoma of the patient, and a proximal portion configured to interface with the tracheostoma components.

A system for a bypass-like, transduodenal passage of stomach contents, comprising: a transduodenal bypass unit (BE), itself comprising a transduodenal assembly (TDG) having a tubular film (7) for the passage of stomach contents into the jejunum, and also comprising a transpyloric assembly (TPG) having a hose-like or tubular shaft component (2); a transesophageal positioning unit (PE) having a tubular shaft component (9), the outer diameter of said shaft component being smaller, at least in a distal region, than the inner diameter of the shaft component (2); and an extracorporeally controllable coupling device (KE) which selectively fixates the shaft component (2) to the shaft component (9) for coupling purposes or releases the same for decoupling purposes.

A system and method for transesophageal echocardiogram-guided implantation of a stent are disclosed. The system includes at least a transesophageal echocardiogram (TEE) system, at least a display and at least a computing device configured to receive a plurality of ultrasound images, generate at least a three-dimensional (3D) cardiac model as a function of the plurality of ultrasound images, receive at least a 3D stent model, determine a view label for each of the plurality of ultrasound images and display the at least a 3D cardiac model and the at least a 3D stent model as a function of the view label.

The invention provides a polypeptide probe for targeted detection of metastatic esophageal tumor drainage lymph nodes and a preparation method and application of the polypeptide probe, and belongs to the technical field of biomedicine, and the constructed bimodal polypeptide probe for targeted tumor metastatic lymph nodes comprises NOTA polypeptide, near-infrared two-region fluorescence signal molecules ICG and 18F-FDG. Compared with the prior art, the bimodal polypeptide fluorescent probe prepared by the invention can be enriched in tumor tissues, can efficiently target a target spot of FGF2 in a positive lymph node, prompts an abnormal metabolism increasing area in a tumor by combining PET / CT, has no obvious biotoxicity, and can be used for detecting the tumor metastatic lymph node through bimodal NIR-II / PET / CT imaging. And accurate early diagnosis and accurate navigation in an operation are realized.

The invention discloses an atrial septum puncture needle tracking method and system based on Transform and a program product, and aims to track the position of a puncture needle in real time through transesophageal echocardiography and improve the tracking precision, robustness and real-time performance of the puncture needle in an operation so as to ensure the safety and efficiency of the atrial septum paracentesis. The atrial septum puncture needle tracking method comprises the steps of data preprocessing, feature extraction, Transform coding, position prediction, trajectory generation and the like. According to the method, by learning a large amount of training data, the tracking robustness is improved, and the method can better adapt to anatomical structure differences and image noise of different patients; a self-attention mechanism is introduced to learn the context relation of the puncture needle in time and space, and the tracking precision is further improved; the real-time performance is improved through parallel computing, and the position of the puncture needle can be tracked in real time in a real-time TEE image sequence.

This design is a medical tube holder that includes a cylindrical tube holding portion with a U-shaped notch that can hold a medical tube, and a throat pad with long holes on both the left and right ends in a plan view for passing a band through. When fixing a tube placed by percutaneous transesophageal gastric tube placement to a patient's neck, the tube is held in place by the tube holding portion, and the back side of the tube is placed against the patient's skin. Bands are passed through the long holes on both the left and right ends of the throat pad to fix the medical tube placed in the patient's body.

The present invention discloses a photoacoustic capsule endoscope and an imaging method. The photoacoustic capsule endoscope includes an optical path folding component, an optical collimating and focusing component, a miniaturized internal scanning component, a port connection component, and a multi-angle imaging probe. The multi-angle imaging probe can be quickly and conveniently replaced through the port connection component to adapt to different types of internal cavities or cavity walls such as the esophagus, rectum, and cervix. By designing the internal structure of the imaging probe and introducing new devices, the device can achieve a miniaturized size of 5mm in diameter and 15mm in hard length, meeting the needs of high-degree-of-freedom, rapid, and non-destructive imaging in the body, expanding the detectable area and imaging depth, avoiding the influence of motion artifacts and image distortion, reducing clinical use costs, and realizing multi-angle full-space endoscopic imaging.