60 results about "Esophago-esophageal" patented technology

A bariatric device and method of causing weight loss in a recipient includes providing a bariatric device having an esophageal member, a cardiac member and a connector connected with the esophageal member and the cardiac member. The esophageal member has an esophageal surface that is configured to generally conform to the shape and size of a portion of the esophagus. The cardiac member has a cardiac surface that is configured to generally conform to the shape and size of a portion of the cardiac portion of the stomach. The esophageal surface is positioned at the esophagus. The cardiac surface is positioned at the cardiac portion of the stomach. The bariatric device stimulates receptors in order to influence a neurohormonal mechanism in the recipient.

A bariatric device includes a body having a wall defining a lumen, the wall configured to generally conform to the shape and size of at least one chosen from i) the abdominal portion of the esophagus, ii) the esophageal-gastric junction, and iii) the proximal cardiac portion of the stomach, with the wall adapted to exert pressure on the at least one chosen from i) the abdominal portion of the esophagus, ii) the esophageal-gastric junction, and iii) the proximal cardiac portion of the stomach, thereby influencing a neurohormonal feedback mechanism of the patient to cause at least partial satiety by augmenting fullness caused by food and simulating fullness in the absence of food.

The invention is a transgastric method for the endoscopic partial fundoplication for the treatment of gastroesophageal reflux disease (GERD). The method makes use of an articulated endoscope, which is introduced through the mouth and esophagus into the stomach of the patient. A cutting tool is introduced through the working channel of the endoscope to cut a hole in the wall of the stomach. The endoscope is pushed through the hole and a grabbing tool is introduced through the working channel and used to grab the tissue at a location on the outer surface of the stomach and move the grabbed tissue close to the esophagus. The grabbed tissue is then stapled to the esophagus using a stapling device that is an integral part of the endoscope. If desired, after stapling the endoscope can be rotated one or more times and the procedure repeated. After the selected portions of the stomach wall have been attached to the esophagus, the endoscope is withdrawn from the body of the patient and the hole in the stomach wall is closed, preferably by means of a dedicated endoscopic stapling device especially designed for the task of closing holes in tissue.

The invention relates to kits and methods for aiding the diagnosis of Barrett's oesophagus or Barrett's associated dysplasia. Preferred is a method comprising assaying cells from the surface of a subject's oesophagus for a non-squamous cellular marker, wherein detection of such a marker indicates increased likelihood of the presence of Barrett's or Barrett's associated dysplasia, preferably wherein said sample of cells is not directed to a particular site within the oesophagus. The invention also encompasses a method comprising sampling the cellular surface of the oesophagus of said subject. The invention also relates to a kit comprising a swallowable device comprising abrasive material capable of collecting cells from the surface of the oesophagus, together with printed instructions for its use in detection of Barrett's oesophagus or Barrett's associated dysplasia. Preferably said device comprises a capsule sponge.

A system comprising: a nasogastric tube comprising: (a) a main lumen having one or more proximal connectors for connecting to a source of substances or pressure, (b) at least four vacuum lumens peripherally surrounding said main lumen, (c) at least four suction ports for sealingly drawing an inner wall of an esophagus thereagainst, each of said at least four suction ports associated with a different one of said four vacuum lumens, wherein said at least four suction ports are distributed between at least two different locations along a longitudinal axis of said nasogastric tube; and an imaging system for capturing and rendering one or more images of an area accessible by said tube, said imaging system comprising: (d) a camera disposed at a distal end of said nasogastric tube, for capturing said images; (e) an illuminator disposed at said distal end of said nasogastric tube, and (f) a processing unit provided at a proximal end of said nasogastric tube, that is configured to receive and process said captured images, render said processed images on a display screen, and provide a camera control signal to control said camera and a light control signal to control said illuminator.

An enteral feeding unit that reduces the occurrence of gastro-esophogeal-pharynegal reflux during feeding includes an automatable feeding pump with a feedback sensor for sensing a relative pressure in a patient's stomach and esophagus, and a regulator system for controlling and monitoring feeding rate to the patient as a function of the relative gastro-esophageal pressure. The system includes a stomach probe that provides a fluid-tight closure of the esophagus. The stomach probe includes a tampon-bladder for watertight closure of the esophagus, in which the tampon-bladder is formed of flexible and / or elastic material. At least an inner cavity of the bladder is provided for the reception of a fluid medium. A prescribed pressure for the medium in the tampon-bladder (53) is maintained by an inner lumen forming the stomach probe, from which an outer hose-like lumen (62) extending to the tampon-bladder (53) is so arranged that between the outer lumen (62) and the inner lumen (61) a channel is formed connected to the inner cavity of the tampon-bladder (53) arranged on the outer lumen (62) by a number of openings (57). The inner cavity (58) of the tampon-bladder (53) is connected via a canal formed between the inner and outer lumina (62) with a suitably graded reservoir or equalizing vessel for the liquid medium situated above the tampon-bladder and outside the patient.

The invention relates to a prosthesis for promoting the in vivo reconstruction of a hollow organ or of a portion of a hollow organ, characterized in that it comprises:a biodegradable hollow tubular support membrane comprising at least one biocompatible and biodegradable polymer material, said support membrane being constituted of a porous outer layer and an essentially non-porous inner layer; anda material of living biological origin at the outer surface, and / or within at least one portion of the porous layer of said support member, and / or over the surface of the essentially non-porous layer facing the porous layer, said material of biological origin being chosen in order to allow the in vivo reconstruction of said organ or of said organ portion.The invention relates to a method for producing such a prosthesis and the medical applications thereof, especially for reconstructing at least one portion of a hollow tubular organ, in particular an esophagus.

The invention relates to a capecitabine pharmaceutical composition, and a preparation method thereof, and belongs to the technical field of medicine. The preparation method of the capecitabine pharmaceutical composition comprises following steps: a prescription dosage of capecitabine, a filler, a dry adhesive, and a disintegrating agent are mixed; an obtained mixture is smashed using an air-flow type pulverizer, and is sieved; an obtained material is mixed using a mixer, a lubricant is added, and an obtained mixed material is mixed uniformly using the mixer, and is subjected to tabletting so as to obtain capecitabine tablets; a coating solution is prepared from a thin membrane coating composition with gastric solubility, and is used for spraying; and obtained coated capecitabine tablets are dried slowly so as to obtain capecitabine thin membrane coated tablets. According to the preparation method, powder direct tabletting method is adopted to produce the capecitabine thin membrane coated tablets; technical processes are simple and few; medicine stability is high; effects are achieved quickly, fully and effectively; irritation of the capecitabine tablets on esophagus can be reduced via thin membrane coating; medicine stability is increased via thin membrane coating; and related substances in the capecitabine thin membrane coated tablets are controlled strictly so as to ensure quality and pharmacy safety of the capecitabine pharmaceutical composition.

The invention provides foreign body removal apparatus for the department of gastroenterology, effectively solves the problem that foreign bodies entering the esophagus mostly are fish bones, fruit pits, bone spurs, and the like, the foreign bodies all have sharp parts, and if the foreign bodies are not removed as soon as possible, the damage to the esophagus is easily caused, and at the same timesolves the problem that the foreign bodies can be pulled out in the opposite direction of the penetration direction by foreign body clamping apparatus when removing the foreign bodies that penetrate into the esophagus, and thereby the damage is minimized. The technical solution to solve the problem is as follows: the foreign body removal apparatus is characterized by comprising expansion apparatusused to expand the mouth, protection apparatus that passes through a space formed by the mouth expansion apparatus and extends into the esophagus, and the foreign body clamping apparatus that passesthrough the protection apparatus and clamps the foreign bodies. The esophagus can be protected while the problem of the damage to the esophagus is solved, and thereby the secondary damage is prevented.

The present invention provides systems and methods for treating and controlling obesity and / or type II diabetes. In one aspect of the invention, an internal bypass device includes gastric and duodenal anchors coupled to each other and positioned on either side of the pylorus and a hollow sleeve designed to extend from the pylorus through at least a proximal portion of a patient's small intestine. The gastric and duodenal anchors are movable between collapsed configurations for advancement through the esophagus and an expanded configuration for inhibiting movement of the anchors through the pyloric sphincter. Thus, the bypass device can be placed and removed endoscopically through the patient's esophagus in a minimally invasive outpatient procedure and it is “self-anchoring” and does not require invasive tissue fixation within the patient's GI tract, thereby reducing collateral tissue damage and minimizing its impact on the digestive process.

This document provides methods and materials that can be used to replace a circumferential segment of an esophagus. For example, methods and materials that can be used to provide a tubular connection from one stump end of an esophagus to another stump end of the esophagus are provided.

A temporary esophagus occlusion device for providing temporary occlusion of the esophagus during intubation of a in patient includes a frame configured to transition between a contracted state, in which it can be swallowed by the patient, and an expanded state, wherein in the expanded state, the frame has a maximum outer diameter sufficient to span an inner diameter of the esophagus of the patient. The device also includes a flexible cover connected to and extending over at least a portion of the frame when the frame is in the expanded state to at least partially block flow of fluid and / or solid materials through the esophagus and a guidewire attached to the frame, sized to be swallowed by the patient along with the frame and having a proximal end portion configured to remain external to the patient's body and a distal end connected to the frame.

The invention discloses a multi-cavity multi-bag tube capable of achieving fixed-point hemostasis. The multi-cavity multi-bag tube is used for solving the problems that in the prior art, a three-cavity two-bag tube cannot effectively determine a bleeding point, and a hemostasis air bag is large in size and is likely to be pressed into a damaged part. The multi-cavity multi-bag tube structurally comprises a catheter, a hemostasis bag, a positioning bag and a stomach bag, wherein the hemostasis bag is arranged on the outer side of the middle of the catheter, the hemostasis bag can expand after being inflated, the bleeding position is pressed, and therefore esophagus bleeding is stopped; the hemostasis bag is composed of a plurality of hemostasis bag bodies with the small length, after the bleeding position is determined through a transnasal gastroscope, only the hemostasis bag body close to the bleeding position is used for hemostasis, the length of the hemostasis bag is small, pressingon the undamaged part is reduced, fixed-point hemostasis is achieved, and the discomfort of a patient is smaller; meanwhile, the positioning bag on the top of the hemostasis bag is fixed into the esophagus after being inflated, and the situation that the catheter moves downwards, and consequently the hemostasis bag moves is avoided; and in addition, the contact area of the conical bag and the stomach is larger, and a better use effect is achieved for fundus hemorrhage.

An esophageal deflection device includes an elongate outer tube that has a natural curved deflection at a position that corresponds to a targeted esophagus region for deflection. The outer diameter of the outer tube is substantially matched to an inner diameter of the esophagus to closely contact the esophagus wall, or is at least half of the inner diameter, or is smaller and includes suction ports for drawing the esophagus wall inward. An insertion rod or tube includes a portion that is stiffer than the curved deflection, and slides into the elongate outer tube to straighten the tube and can serve to guide the deflection device into an esophagus. Subsequent withdrawal of the insertion tube or rod will allow the curved deflection to return to its natural shape and deflect the targeted region of the esophagus. A three-dimensional array of temperature sensors can be disposed near an outer surface of the elongate outer tube.

The invention discloses a novel medical anti-reflux stomach tube. The stomach tube comprises a main stomach tube body, an inner-layer stomach tube, diaphragms, hollow cavities, a nutrient solution channel, a nutrient solution outlet, an inflatable radiography tube and a radiography air bag, wherein the inner-layer stomach tube is arranged in the main stomach tube body; a plurality of diaphragms are arranged between the inner-layer stomach tube and the main stomach tube body; the hollow cavities are formed between every two diaphragms; the nutrient solution channel is formed in the inner-layerstomach tube; the nutrient solution outlet is formed in the bottom of the nutrient solution channel; the nutrient solution outlet penetrates through the main stomach tube body; the inflatable radiography tube is also arranged in the inner-layer stomach tube; and the radiography air bag is arranged at the bottom of the inflatable radiography tube. Compared with the prior art, the novel medical anti-reflux stomach tube has the advantages of simple structure, reasonable design, convenience in use and insertion, and capability of effectively preventing the reflux of stomach liquid, monitoring changes in the internal pressure of the stomach and the pH value of the esophagus of a patient in real time, and facilitating the care work of medical personnel.

The invention discloses an inflation-free laryngeal mask tracheal tube. The inflation-free laryngeal mask tracheal tube includes a main tube base, a ventilation tube and a cover cap, wherein the ventilation tube can be bent and is connected with the main tube base, and the cover cap covers the periphery of the main tube base and is closely cooperated with the ventilation tube, the cover cap has an adsorption end face, a first through hole is formed in the adsorption end face, a second through hole is also formed in the cover cap, the periphery of the ventilation tube is sleeved with the second through hole and closely cooperated with the ventilation tube, the main tube base is located between the first through hole and the second through hole, the cover cap is made from elastic memory materials, when the cover cap stretches into the throat, the adsorption end face is completely adsorbed onto the airway and is not inserted in the esophagus, and the ventilation tube is in seal communication with the airway. The adsorption end face is arranged on the cover cap and adsorbed mutually with the airway after being smeared with mucus, so that the cover cap and the airway are in a seamless seal state, the sealing effect is good, the cover cap does not invade the inside of the esophagus, independent management of the airway and the esophagus is achieved, the laryngeal mask tracheal tube is suitable for the physiological structures of easterners, and risks of regurgitation and aspiration are avoided.

The invention provides an esophageal cancer detection method and system based on a barium meal contrast image. The method comprises the following steps: acquiring the barium meal contrast image of an esophagus to be detected; performing focus area detection on the barium meal contrast image according to the trained target detection model; wherein the target detection model adopts an improved Faster R-CNN, and a basic network of the target detection model is composed of a convolutional neural network carrying an attention mechanism; obtaining a feature map of the image according to the basic network, and enhancing the feature saliency of the feature map through an attention mechanism; and generating a region of interest and a feature vector of the region of interest according to the feature map, and obtaining detection information of the lesion region according to the feature vector of the region of interest. The attention mechanism is embedded in the basic network, the capability of obtaining the features of the region of interest of the target detection model is improved, and the esophageal cancer detection accuracy of the system is improved through fusion of multi-image and multi-body-position detection information.

An esophageal monitoring device includes a camera and, optionally, one or more lights to enable visualization of an interior of a subject's esophagus. Visualization of the interior of the subject's esophagus before and after a left atrial ablation procedure may enable a healthcare provider to determine whether or not the left atrial ablation procedure has damaged the subject's esophagus before the subject experiences any symptoms of such damage. An esophageal monitoring device may also include sensors and / or markers that enable a determination of its location within a subject's esophagus. Such an esophageal monitoring device may be configured for three-dimensional mapping, and enable the generation of an accurate three-dimensional map of the physical relationship between a subject's esophagus and the left atrium of his or her heart. Methods of monitoring a subject's esophagus while a left atrial ablation procedure is being conducted on the subject's heart are also disclosed.

There is provided system for monitoring spontaneous breathing of a mechanically ventilated target individual, comprising: a feeding tube for insertion into a distal end of an esophagus of the individual, sensor(s) disposed on the feeding tube at a location such that the sensor(s) is located at the distal end of the esophagus of the individual when the feeding tube is in use, wherein the sensor(s) is positioned for sensing values by contact with the tissue of the esophagus including a lower esophageal sphincter (LES) and / or tissue in proximity to the LES, and code for computing an indication of a frequency band of diaphragm movement of the individual according to an analysis of values sensed by the sensor(s), and for adjustment of parameter(s) of a mechanical ventilator for mechanically ventilating the individual, wherein the instructions for adjustment are computed while the feeding tube is in use.

An esophageal monitoring device includes a camera and, optionally, one or more lights to enable visualization of an interior of a subject's esophagus. Visualization of the interior of the subject's esophagus before and after a left atrial ablation procedure may enable a healthcare provider to determine whether or not the left atrial ablation procedure has damaged the subject's esophagus before the subject experiences any symptoms of such damage. An esophageal monitoring device may also include sensors and / or markers that enable a determination of its location within a subject's esophagus. Such an esophageal monitoring device may be configured for three-dimensional mapping, and enable the generation of an accurate three-dimensional map of the physical relationship between a subject's esophagus and the left atrium of his or her heart. Methods of monitoring a subject's esophagus while a left atrial ablation procedure is being conducted on the subject's heart are also disclosed.

A laryngeal mask airway (LMA) for gastroscopy includes a laryngeal tube for gastroscopy. A drainage tube is fixedly installed on an outer surface of an upper end of the laryngeal tube for gastroscopy. A PC connector is fixedly installed at one end of the drainage tube. A ventilation hole is formed in an outer surface of an upper end of the drainage tube, and a suction hole is formed in an outer surface of a lower end of the laryngeal tube for gastroscopy. An inner cavity and an inflation tube hole are formed inside the laryngeal tube for gastroscopy. The inflation tube hole is disposed under the inner cavity and receives an inflation tube, and a single-cavity connector is fixedly installed at one end of the inflation tube. The LMA absorbs secretions from a patient's esophagus to minimize coughing during a gastroscopy, thereby reducing patient discomfort and pain.

A device and method is provided herein for esophageal impingement of a patients aorta. The device may be inserted into a patients esophagus and positioned at the location where the esophagus passes over the patients aorta. In this position, an actuation device is used to apply pressure to the patients aorta through their esophagus to impinge or occlude the aorta to stop or significantly reduce hemorrhaging. A manually operable actuator handle enables a physician to manipulate a head assembly of the device through three distinct degrees of freedom of movement so as to control placement and direction of force against the patients esophagus and, in turn, their aorta.

The present invention relates to a biologically active graft (BAG) composition and methods for its preparation and use.More particularly, it details a method for preparing a non-immunogenic tissue graft composition comprising esophagus mucosa, basement membrane and tunica submucosa as intact natural sheet forms (Ad integrum), delaminated from the tunica muscularis and adventitia of an esophagus of a warm-blooded vertebrate.The composition is capable of serving as a substitute for skin autograft for skin replacement therapy and induces stromal cells regeneration when implanted in warm-blooded vertebrate including human subjects.

The invention discloses an esophagus applicator for the digestive system department, and relates to the technical field related to medical instruments, the esophagus applicator comprises a handheld tube, the front end of the handheld tube is fixedly connected with an insertion tube, the end, away from the handheld tube, of the insertion tube is fixedly connected with an applying head, the applying head is provided with a plurality of outflow holes, and the handheld tube is provided with a medicine storage assembly, a pressurizing mechanism and an inflating assembly; the medicine storage assembly comprises a medicine storage barrel fixedly arranged on the handheld pipe, the top end of the medicine storage barrel is in threaded connection with a sealing cover, the bottom end in the medicine storage barrel is fixedly connected with a gathering base, and the center of the gathering base is fixedly connected with a medicine placing assembly; by arranging the medicine storage assembly, needed medicine can be stored, by arranging the pressurizing mechanism, the medicine can be continuously output, conveying and stopping of the medicine can be controlled, by arranging the inflating assembly, the softness degree of the inserting pipe can be controlled, adjustment can be conveniently conducted according to use requirements, and the practicability is high. The esophagus applicator is good in medicine applying assistance for the esophagus of the digestive system department, easy to operate and high in functionality.

The invention provides a traditional Chinese medicine composition for protecting liver and stomach and dispelling effects of alcohol, a preparation and a preparation method thereof, which relate to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition has the effects of soothing the liver, regulating qi, regulating the middle warmer, strengthening the spleen, relieving alcoholism, cooling and inducing diuresis, and can play roles in protecting the liver and nourishing the stomach while relieving alcoholism. The fructus citri, the perilla leaves and the hovenia dulcis thunb are reasonably matched and can achieve a synergistic effect, the effect of soothing the liver and regulating qi is finally achieved, the influence of drunkenness on the esophagus is effectively avoided, the motor function of the esophagus is recovered, the esophagus muscle is not relaxed any more, meanwhile, the phenomenon of gastric acid increase is avoided, the reduction of the gastric excretion function is avoided, and stable liver metabolism is guaranteed. The raw materials in the traditional Chinese medicine composition are pure traditional Chinese medicines, have no toxic or side effect on the body and no drug resistance, are different from components such as stimulants, vitamins and amino acids in chemical anti-alcohol medicines, are healthier and are beneficial to body conditioning of users.

The invention discloses an oral cavity opener and a trachea cannula auxiliary device and a using method thereof. The oral cavity opener comprises tooth sockets matched with an upper gum structure and a lower gum structure respectively; the two tooth sockets are connected through a plurality of supporting assemblies, each supporting assembly supports the two tooth sockets to be attached to the upper gum and the lower gum respectively, and a tongue depressor is arranged on the tooth socket corresponding to the lower gum. The tongue depressor is of an arc-shaped structure matched with the tongue, the front end of the tongue depressor extends towards the throat and covers the epiglottis in a pressing mode, firstly, the supporting assembly is combined with the tooth socket to open the upper gum and the lower gum, the oral cavity is completely opened, then the tongue depressor covers the tongue in a pressing mode, the throat of the human body is exposed, and the front end of the tongue depressor covers the epiglottis in a pressing mode; therefore, openings of the esophagus and the trachea of a human body are completely exposed, plugging of the esophagus and insertion of a trachea cannula are facilitated, the tongue depressor is provided with baffles used for supporting cheek parts on the two sides in the oral cavity respectively, the baffles are fixed to the edges of the two sides of the tongue depressor respectively, and the opening effect of the oral cavity is further guaranteed.

The present invention is directed to compositions, methods and systems for identifying, in real time, the position and orientation of the esophagus prior to and during atrial fibrillation ablation procedures, so as to avoid or reduce the incidence of atrioesophageal fistula (AEF). The compositions, methods and systems of the present invention include the identification and visualization of the esophagus, the rapid and accurate integration of the visualized esophagus into an anatomical map together with the posterior wall of the left atrium, in each case presented as a 3-D map, so as to facilitate the accurate identification of those areas of the esophagus that lie in contact with or in near proximity to those areas of the posterior wall of the left atrium that the operator intends to ablate.