Multifunctional automatic cardio-pulmonary resuscitation first-aid equipment comprises a base, a platform, a pressing plate, a connecting rod, a screw nut, a ball screw, a stand column, a servo motor, a host, a touch screen, a manual input device, an automatic defibrillation device, a heart rate detection sensor, a cooling gas generation device and a hood provided with a hollow interlayer, wherein the front end of the screw nut is connected with the pressing plate through the connecting rod; the automatic defibrillation device is connected with the host; the heart rate detection sensor is connected with the host; the hood provided with the hollow interlayer is connected with the cooling gas generation device. The equipment has the advantages as follows: accurate pressing depth and pressing frequency of a patient can be automatically controlled in the emergent treatment process of cardiac arrest, waveforms of ventricular fibrillation are automatically recognized, defibrillation is triggered, smoothness of an airway is kept, mechanical assisted ventilation is provided, the dependence on a special doctor in the emergent treatment process is reduced, the accuracy and the automatic degree are improved, the cardio-pulmonary resuscitation effectiveness is guaranteed, brain death is reduced, and the multifunctional automatic cardio-pulmonary resuscitation first-aid equipment can be applied in a wide range.