Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Piroxicam tablets and preparation process thereof

A kind of technology of piroxicam tablet and preparation process, applied in the field of piroxicam tablet and its preparation, can solve the problems such as unsatisfactory curative effect

Inactive Publication Date: 2014-06-18
崔书豪
View PDF2 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Existing drugs for the treatment of rheumatoid arthritis and painful osteoarthritis (arthrosis, degenerative joint disease) have unsatisfactory curative effects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Piroxicam tablets and preparation process thereof
  • Piroxicam tablets and preparation process thereof
  • Piroxicam tablets and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0017] The present invention is further explained below in conjunction with the examples, but the examples do not limit the present invention in any form.

[0018] (1) Making tablet cores: pass piroxicam, lactose, pregelatinized starch, hydroxypropyl methylcellulose, and sodium starch glycolate through a 100-mesh sieve, and add them into the wet mixing granulator according to the method of equal increments and mix evenly , to obtain mixed powder; dissolve polysorbate-80 in 30-50 times of ethanol, add to the above mixed powder, mix, and then add 15% pregelatinized starch for pulping to the mixed powder to make 18 ~40-mesh granules, dried at 60-70°C, sieved with 24-mesh sieve, collected when the water content is 1.0-3.0%, and prepared tablet cores for later use;

[0019] (2) Coating: the stomach-soluble film coating premix is ​​formulated with 80% ethanol into a 11% suspension, stirred and mixed for 60 minutes for later use; the tablet cores are poured into the coating pot, and ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses piroxicam tablets and a preparation process and purposes thereof. The product consists of piroxicam, lactose, pregelatinized starch, hydroxypropyl methyl cellulose, carboxymethyl starch sodium, polysorbate-80, 15% pregelatinized starch for slushing, superfine silica powder, magnesium stearate and a gastric soluble film coating premix. The production method comprises the steps: preparing tablet cores, coating and the like. The piroxicam tablets are used for treating 30 cases of rheumatoid arthritis, have good curative effects of diminishing inflammation and relieving pain and have slight influence on erythrocyte sedimentation rate, the total effective rate is 88 percent, and the piroxicam tablets have the characteristics of low administration frequency, stable blood concentration, long duration and the like.

Description

field of invention [0001] The invention relates to the field of chemical pharmacy, in particular to a piroxicam tablet and a preparation process thereof. Background of the invention [0002] Arthritis is a common and chronic disease, in which osteoarthritis and rheumatoid arthritis are the main forms. According to reports, about 18% of the people in our country suffer from some form of arthritis, and the number of cases exceeds 200 million. Arthritis is a serious threat to human health, affecting the life and work of patients, making some patients unable to take care of themselves and lose their ability to work. Some patients have restricted activities, joint swelling, stiffness and pain, and severe joint permanent deformation, which is an important cause of disability in the elderly, so timely treatment is required. [0003] Piroxicam (Piroxicam), also known as Pyroxicam, Pyroxythiazine, Anerke, Xipukang, Feidine, the chemical name is 2-methyl-4-hydroxy-N-(2-pyridyl)- 2H...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K9/28A61K31/5415A61P29/00A61P19/02
Inventor 崔书豪王志刚薛清佩陈洪瑜
Owner 崔书豪
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com