Analgesic cold patch and preparation technology thereof

A preparation process, the technology of sodium polyacrylate, applied in the field of medical devices, can solve the problems that the analgesic effect cannot be exerted, the drug ingredients cannot fully penetrate into the human skin, and the analgesic effect is not ideal.

Active Publication Date: 2017-11-24
贵州梵天苗成医疗器械科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Among them, analgesia is an important application direction of cold compresses, but the analgesic effect of existing cold compresses is not ideal enough, especially the added pharmaceutical ingredients cannot fully penetrate into human skin, and cannot exert better analgesic effect. causing waste of drugs

Method used

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  • Analgesic cold patch and preparation technology thereof
  • Analgesic cold patch and preparation technology thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A preparation process of analgesic cold compress, the specific method is: firstly add the first part of sodium polyacrylate, glycerol, crospovidone, polymethacrylic acid and iron oxide black into glycerin to make an oil phase; Then tartaric acid, preservatives, the second part of sodium polyacrylate, traditional Chinese medicine extract, honey and water are mixed, supplemented with penetration enhancer, stabilizer, wintergreen oil, menthol and thermal agent to make the water phase; finally The oil phase and the water phase are vacuum mixed to obtain a hydrogel matrix, coated, cut, packaged, and solidified in a bag; wherein, the mass ratio of the first part of sodium polyacrylate to the second part of sodium polyacrylate is 5:3.

[0037] Specific steps are as follows:

[0038] (1) Add the first part of sodium polyacrylate, glycerol, crospovidone, polymethacrylic acid and iron oxide black into glycerin, and mix well to obtain an oil phase;

[0039] (2) After mixing the p...

Embodiment 2

[0054] A preparation process of analgesic cold compress, the specific method is: firstly add the first part of sodium polyacrylate, glycerol, crospovidone, polymethacrylic acid and iron oxide black into glycerin to make an oil phase; Then tartaric acid, preservatives, the second part of sodium polyacrylate, traditional Chinese medicine extract, honey and water are mixed, supplemented with penetration enhancer, stabilizer, wintergreen oil, menthol and thermal agent to make the water phase; finally The oil phase and the water phase are vacuum mixed to obtain a hydrogel matrix, coated, cut, packaged, and solidified in a bag; the mass ratio of the first part of sodium polyacrylate to the second part of sodium polyacrylate is 7:6.

[0055] Specific steps are as follows:

[0056] (1) Add the first part of sodium polyacrylate, glycerol, crospovidone, polymethacrylic acid and iron oxide black into glycerin, and mix well to obtain an oil phase;

[0057] (2) After mixing the penetratio...

Embodiment 3

[0072] A preparation process of analgesic cold compress, the specific method is: firstly add the first part of sodium polyacrylate, glycerol, crospovidone, polymethacrylic acid and iron oxide black into glycerin to make an oil phase; Then tartaric acid, preservatives, the second part of sodium polyacrylate, traditional Chinese medicine extract, honey and water are mixed, supplemented with penetration enhancer, stabilizer, wintergreen oil, menthol and thermal agent to make the water phase; finally The oil phase and the water phase are vacuum mixed to obtain a hydrogel matrix, coated, cut, packaged, and solidified in a bag; the mass ratio of the first part of sodium polyacrylate to the second part of sodium polyacrylate is 6:5.

[0073] Specific steps are as follows:

[0074] (1) Add the first part of sodium polyacrylate, glycerol, crospovidone, polymethacrylic acid and iron oxide black into glycerin, and mix well to obtain an oil phase;

[0075] (2) After mixing the penetratio...

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Abstract

The invention provides an analgesic cold patch and a preparation technology thereof. The specific method comprises the steps of firstly adding a first part of sodium polyacrylate, dihydroxyaluminum aminoacetate, polyvinylpolypyrrolidone, polymethylacrylic acid and iron oxide black to glycerin to prepare an oil phase; mixing tartaric acid, a preservative, a second part of sodium polyacrylate, a traditional Chinese medical extract, honey and water, and supplementing a penetration enhancer, a stabilizer, wintergreen oil, menthol and a heat sensitizer to prepare an aqueous phase; and finally mixing the oil phase with the aqueous phase in vacuum to obtain a hydrogel matrix, carrying out coating, cutting, packaging and curing in a bag to obtain the analgesic cold patch. The prepared cold patch has an excellent analgesic effect and has relatively good caking property with human skin.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to an analgesic cold compress and a preparation process thereof. Background technique [0002] The cold compress is improved according to the traditional cold compress method (cold water, ice water or alcohol). It takes away the heat through the vaporization of the water contained in the polymer gel and the natural cooling ingredients, and can achieve local cooling. Combined with the gel, through hydration, the drug ingredients can quickly pass through the fat layer, penetrate into the subcutaneous tissue, directly reach the lesion site, act on the affected area, and achieve the effects of cold compress pain relief, transdermal absorption, and sustained release drug delivery. [0003] Cold compresses can shrink local capillaries, relieve local congestion, reduce the sensitivity of nerve endings and relieve pain, reduce temperature and fever, reduce local blood flow, and prev...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K36/888A61P29/00
CPCA61K9/7076A61K36/14A61K36/185A61K36/235A61K36/282A61K36/484A61K36/537A61K36/87A61K36/88A61K36/888A61K2300/00
Inventor 田茂富
Owner 贵州梵天苗成医疗器械科技有限公司
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