3results about How to "Improve transdermal absorption rate" patented technology

This invention belongs to the field of traditional Chinese medicine technology, specifically relating to a herbal antibacterial hydrogel for ulcer healing, its preparation method, and its application. The hydrogel is composed of a herbal composition and a matrix. The herbal composition includes dandelion, angelica, scrophularia, forsythia, phellodendron, atractylodes, angelica dahurica, and raw licorice. The matrix contains chitosan, polyvinyl alcohol, water, and glacial acetic acid. The effective components of the herbal medicine are extracted by decoction, concentrated, and freeze-dried to obtain a freeze-dried powder. This powder is then mixed with a chitosan aqueous solution and cross-linked using a liquid nitrogen cyclic freezing method to form the hydrogel. This invention closely addresses the core pathogenesis of diabetic foot ulcers—"blood stasis, dampness, and heat (toxin)"—allowing the various herbs to synergistically exert their effects of clearing heat and detoxifying, promoting blood circulation and removing blood stasis, drying dampness and astringing sores, and nourishing blood and promoting tissue regeneration. The chitosan matrix endows the hydrogel with good biocompatibility, antibacterial properties, and sustained-release drug properties, which can improve the microenvironment of the ulcer wound, inhibit inflammatory responses, and promote granulation tissue growth, effectively promoting the healing of skin sores such as diabetic foot ulcers, and has broad application prospects.

The utility model belongs to the technical field of medical auxiliary instrument, concretely relates to a percutaneous electric medicine synergic treatment device, including host computer and with the electric medicine treatment unit of host computer electric connection, the electric medicine treatment unit includes annular adhesive member, ring electrode, drug loading disc and medicine gel piece, annular adhesive member, ring electrode and drug loading disc coaxial arrangement, ring electrode is fixed between drug loading disc side surface and annular adhesive member inboard, the thickness of drug loading disc is less than the thickness of ring electrode, and the inboard of ring electrode and the surface of drug loading disc form the recessed cavity for accommodating medicine gel piece, and when medicine gel piece sets up in recessed cavity, medicine gel piece side surface and ring electrode inboard are pasted. The utility model can improve medicine transdermal absorption rate on the basis of guaranteeing electric stimulation itself effect, thereby more effectively realizes electric stimulation and medicine synergic effect, to improve synergic curative effect, realizes the flexible replacement use of different function medicine gel piece, satisfies the individualized treatment demand.

This invention discloses a plant essential oil microemulsion hydrogel fever-reducing patch and its preparation method. The fever-reducing patch comprises, by weight, phase A, phase B, an alkyl glycoside green surfactant system, and a hydrogel matrix; phase A consists of lavender essential oil, melaleucalyptus essential oil, cardamom essential oil, Roman chamomile essential oil, pine needle essential oil, and α-bisabolol; phase B consists of peony bark extract and peony root extract; the alkyl glycoside green surfactant system consists of alkyl glucoside, lecithin, and glycerol. This invention prepares phases A and B, along with the green surfactant system, into a microemulsion with a particle size of 20-60 nm, which is then mixed with the hydrogel matrix and coated onto a non-woven fabric backing layer to form the fever-reducing patch. This fever-reducing patch achieves a rapid, safe, and comfortable auxiliary fever-reducing effect through a synergistic effect of antiviral, anti-inflammatory, sedative, antispasmodic, and antipyretic mechanisms.