The invention discloses a super-hydrophobic/super-oleophylic stainless steel mesh for oil-water separation and a preparation method thereof. The preparation method comprises the following steps: ultrasonically cleaning a stainless steel mesh with deionized water, then performing drying, soaking the clean stainless steel mesh in a dilute strong acid solution for corrosion, taking out the corroded stainless steel mesh, ultrasonically cleaning the corroded stainless steel mesh, and drying the cleaned stainless steel mesh; soaking the stainless steel mesh after corrosion in a salt solution of an inactive metal, performing reacting, taking out the reacted stainless steel mesh, ultrasonically cleaning the reacted stainless steel mesh, and performing drying; finally, soaking the dried stainless steel mesh in a long-chain alkyl organic acid solution for reaction and then taking out the reacted stainless steel mesh, performing ultrasonic cleaning and drying, so as to finally obtain the super-hydrophobic/super-oleophylic stainless steel mesh. The oil-water separation filter mesh prepared by the method has the advantages of being high in oleophylic speed, good in hydrophobic effect, not easyto fall off and reusable for many times, the separation of oil-containing wastewater can be realized quickly and efficiently, and the stainless steel mesh has good separation effect on kerosene, gasoline, liquid paraffin, toluene and the like and also has good separation effect on strong-acidity, strong-alkaline and high-salinity oil-containing wastewater, and has a wide application prospect in the fields of petrochemical environment protection and the like.