117 results about "Tumor cell membrane" patented technology

The invention discloses a tumor-targeted CD38-pH low insertion peptide (pHLIP) fusion peptide. The fusion peptide is formed by connecting a pHLIP and a functional structure domain of CD38. The tumor microenvironment is acidic, under the acidic environment, the pHLIP can be inserted into a tumor cell membrane, by utilizing the properties of the pHLIP, the CD38 connected with the pHLIP is positionedon the surface of the tumor cell membrane in a targeted mode, through the technology, original tumor cells with tumor cell surfaces not expressing the CD38 can also be marked by the CD38, and thus antibody drugs aiming at the CD38 can exert the effects on the original tumor cells not expressing the CD38 as well. Through the research results, the indications of a specific tumor antibody drug are expanded, and clinical application prospects are good.

The invention relates to angstrom-silver injection liquid capable of inhibiting cancer as well as a preparation method and application thereof. The injection liquid comprises the following componentsaccording to proportion: angstrom-grade elemental silver powder (0.005 to 0.500 g / L), medicinal anhydrous fructose (0.5 to 1.0 g / L) and aseptic distilled water (998.500 to 999.495 g / L). The surface ofa tumor cell membrane takes on high negative charge property, increment of the negative charges on the surface of the membrane is related to the side-chain charges of acidic mucopolysaccharide, DNA and protein on the surface of the membrane, particularly related to increment or revealing of the quantity of sialic acid. The angstrom-silver and silver ions have positive charges, so the angstrom-silver and the silver ions can be bound with protein and nucleic acid molecules, with negative charges, inside and outside cells, synthesis of the protein and replication and transcription of the DNA areinterfered, and the normal vital movement of the cancer cells is damaged.