78results about How to "Reduce synthesis" patented technology

The invention relates to a weight-losing enzyme and a preparation method thereof, and belongs to the technical field of biology, and the weight-losing enzyme comprises a fruit enzyme, a vegetable enzyme, a seed enzyme and a lotus leaf extract; the fruit enzyme is obtained by performing enzymolysis on mixed fruit pulp of apples, lemons, grapefruits and haws through pectinase, performing enzymolysis through pepsase and performing co-fermentation through bifidobacterium longum and lactobacillus acidophilus; the vegetable enzyme is obtained by performing enzymolysis on mixed vegetable pulp of wax gourd pulp, celery and spinach through pectinase, performing enzymolysis through pepsin and performing fermentation through lactobacillus plantarum and bifidobacterium adolescentis; the seed enzyme is obtained by carrying out trypsin enzymolysis on mixed powder of semen raphani and phaseolus calcaratus, then carrying out nattokinase enzymolysis and then fermenting with bifidobacterium breve; the lotus leaf extract is obtained by sequentially carrying out enzymolysis on lotus leaves through hemicellulase, snail protease and nattokinase. All the components are matched for use, so that the weight-losing food has the effects of promoting digestion, inhibiting fat absorption, regulating intestinal flora, promoting metabolism and the like, and has a good weight-losing effect.

The invention provides a whitening composition, a whitening product, a preparation method and application. The invention provides application of the milk exosome and nicotinamide in improving the autophagy ability of tranexamic acid activated melanocytes. The whitening composition provided by the invention is prepared from the following components in parts by weight: 1 to 50 parts of milk exosome, 5 to 40 parts of tranexamic acid and 0.5 to 30 parts of nicotinamide. The provided whitening composition is an active composition capable of activating the autophagy function of melanocytes of a human body, melanin synthesis in the melanocytes can be reduced by inducing generation of autophagy-related protein and activating an autophagy system, dullness of the skin is improved, the skin color is brightened through an internal channel, and the product is free of irritation and high in safety.

The invention provides anti-aging collagen peptide mask liquid and a preparation method thereof. The mask liquid is prepared from the following components in percentage by mass: 1 to 2 percent of tremella polysaccharide, 3 to 4 percent of herba portulacae extract, 2 to 3 percent of radix gentianae extract, 0.3 to 0.8 percent of nicotinamide, 1.2 to 1.6 percent of alpha-arbutin, 0.2 to 0.6 percent of chrysanthellum indicum extract, 0.7 to 1.5 percent of geranium flower / leaf / stem extract, 0.4 to 0.8 percent of aloe barbadensis extract, 0.7 to 1.3 percent of radix sophorae flavescentis extract, 0.3 to 0.9 percent of herba houttuyniae extract, 1.2 to 1.7 percent of herba centellae extract and the balance of water. The traditional Chinese medicine composition is prepared from the following raw materials in percentage by weight: 0.2 to 0.6 percent of fructus hippophae extract, 0.02 to 0.06 percent of peony root bark extract, 0.06 to 0.09 percent of scutellaria baicalensis root extract, 0.04 to 0.08 percent of rosemary extract, 0.01 to 0.04 percent of pearl powder and the like. The mask liquid prepared by the invention has an anti-aging effect.

According to the method for promoting the fragrance release of the Phalaenopsis amabilis in the flowering stage, the influence of flowering days, different light intensities and different temperatures on the fragrance release in the full-bloom stage is compared, and the light and temperature adaptability of the fragrance of potted Phalaenopsis amabilis in the full-bloom stage is proved; and a basic basis can be provided for breeding aromatic phalaenopsis varieties and researching the action mechanism of the flower fragrance of important economic ornamental flowers. Meanwhile, the optimal culture medium formula of each link of tissue culture and rapid propagation of the phalaenopsis purpurascens is further deeply researched, discussed and screened, so that the phalaenopsis purpurascens can be developed and applied on an industrial scale.

The invention provides a virtual screen processing method and electronic equipment, and is applied to the technical field of terminals. The method comprises the following steps: when an image processing process performs GI synthesis of a first frame, using a communication thread in the image processing process to communicate with an application process to obtain a communication result. And when the communication result is normal, sending the synthesized GI to a virtual screen created by the application process. And when the communication result is abnormal, deleting the virtual screen object. At the moment, when the application process does not respond in time or communication with the image processing process is abnormal, the task thread of the image processing process is prevented from being blocked, so that the abnormal influence is controlled in the communication thread, and other task threads are not influenced. Thus, the communication thread is split from the image synthesis thread, the communication thread is used for communicating with the application process, the frozen screen problem of the display interface of the electronic equipment is solved to a certain extent, and the equipment stability and the user experience are improved.

The invention relates to a fertilizer synergistic composition, a special corn fertilizer and a preparation method thereof, and belongs to the technical field of fertilizers. The fertilizer synergistic composition comprises the following components in percentage by weight: 0.6%-5.0% of polyaspartic acid, 1.2%-4.0% of polyacrylamide, 0.3%-2.0% of a nitrification inhibitor and the balance of zeolite powder. The invention also provides a special corn fertilizer containing the fertilizer synergistic composition. The polyacrylamide in the composition provided by the invention can improve the soil structure, increase the porosity and air permeability of the soil, improve the water retention capacity of the soil and reduce the permeability of the soil, so that the fertility of the soil and the yield of crops are improved. According to the fertilizer synergist, the utilization degree of a fertilizer is increased, the release speed of the fertilizer is controlled, and the fertilizer can act for a long time.

The invention provides a sphingomonas paucimobilis CRISPRi / dCas12a gene regulation system as well as a construction method and application thereof, and particularly belongs to the technical field of gene engineering. The gene regulation and control system disclosed by the invention comprises a pBBR1-dCas12a-crRNA plasmid, wherein the plasmid comprises a pBBR1 replicon, a dCas12a gene, a crRNA expression cassette and a chloramphenicol resistance gene; the crRNA expression cassette comprises a Ptac promoter, two DR fragments and an rrnB T1 terminator, and is characterized in that the crRNA expression cassette comprises a Ptac promoter, two DR fragments and an rrnB T1 terminator. The system disclosed by the invention can stably express in sphingomonas paucimobilis and inhibit the transcription of genes so as to reduce the expression of specific genes without modifying the DNA (Deoxyribose Nucleic Acid) sequence of the specific genes, has lower toxicity to S.paucimobilis, is high in host growth speed and can realize the efficient expression of dcas12a.

The invention provides a pharmaceutical composition containing lactoferrin and application of the pharmaceutical composition in blood fat reduction. Specifically, the KGT-C polypeptide provided by the invention has a very strong effect of reducing the synthesis amount of cholesterol in cells, and after the KGT-C polypeptide is combined with lactoferrin, the generation of cholesterol and LDL can be remarkably reduced, so that the KGT-C polypeptide has a relatively good effect of treating hyperlipidemia.

The invention discloses recombinant escherichia coli for producing N-acetylneuraminic acid as well as a construction method and application of the recombinant escherichia coli, and belongs to the technical field of genetic engineering. According to the invention, 6-phosphofructokinase is knocked out, glycerol kinase is introduced into a glycerol kinase mutant, a diffusion transporter is promoted by glucose to replace PTS phosphotransferase I, and a promoter is optimized, so that recombinant escherichia coli can grow by double carbon sources of glucose and glycerol, N-acetylneuraminic acid is synthesized, and meanwhile, the generation amount of acetic acid is extremely low. On the basis, a 6-phosphofructokinase coding gene pfkB is knocked out, a heterologous ED pathway from pseudomonas mobilis is introduced, and the yield under the pore plate level is further increased to 9.44 g / L through copy number optimization and RBS strength optimization.

The invention relates to the field of genetic engineering, in particular to a genetically engineered bacterium for efficiently synthesizing 5-aminolevulinic acid. According to the invention, a synthetic biological technology and a genetic engineering means are utilized, escherichia coli E.coli BL21 (DE3) is taken as an original strain, a C5 way of the escherichia coli E.coli BL21 (DE3) is modified, and degradation of glutamic acid is reduced by knocking out a gadA gene and replacing a promoter of an argE gene; the synthesis of the 5-aminolevulinic acid is increased by enhancing the expression of gdhA, hemAS and hemL genes, replacing promoters and increasing the carbon flux flowing to the 5-aminolevulinic acid; in addition, by knocking out acetic acid synthesis genes ackA, poxB and pta, the loss of carbon flux flowing to TCA circulation is reduced, so that the purpose of increasing the yield of 5-aminolevulinic acid is achieved.

The invention provides a method for reducing acetic acid in a succinic acid fermentation process, and belongs to the technical field of fermentation. In the step of fermentation culture, a fermentation aid is fed in a fermentation culture process, specifically, when fermentation is performed for 10h, a fermentation aid I is fed into a fermentation culture tank at the feeding speed of 0.07-0.09 ml / h / L until fermentation is finished; when the fermentation is performed for 24 hours, feeding a fermentation aid II into the fermentation culture tank at the feeding speed of 0.12-0.14 ml / h / L until the fermentation is finished; the fermentation aid I comprises cobalt chloride hexahydrate, zinc sulfate heptahydrate, folic acid and biotin; the fermentation auxiliary agent II comprises nicotinamide, cysteine and tyrosine; the content of the fermentation culture solution prepared by the method disclosed by the invention is as high as 59.1-60.4 g / L, the content of acetic acid is as low as 0.30-0.65 g / L, and the content of malic acid is 0.20-0.23 g / L.

The invention provides lactobacillus reuteri Ligh-alpha with whitening and anti-aging activity and related application thereof, and relates to the technical field of microorganisms and application thereof. The Lactobacillus reuteri Ligh-alpha is preserved in the General Microbiological Culture Collection Center of the China Committee for Culture Collection of Microorganisms on January 2, 2024, and the preservation number of the Lactobacillus reuteri Ligh-alpha is CGMCC No. 29488. The lactobacillus reuteri Ligh-alpha provided by the invention can be used for effectively inhibiting the activity of tyrosinase and reducing melanin synthesis; meanwhile, the Ligh-alpha strain also has excellent free radical scavenging ability and relatively high reducing power, shows very strong antioxidant ability, and can tolerate acid-base and cholate environments. Therefore, the Lactobacillus reuteri Ligh-alpha strain has a wide market application prospect in the aspect of preparing products for whitening, resisting oxidation, resisting aging and the like.

The invention belongs to the technical field of chemical synthesis, and particularly relates to a method for preparing peroxy acid. The method comprises the following steps: S1, carrying out reaction on organic acid, hydrogen peroxide, a catalyst and a solvent in a first pre-reactor, and introducing a product obtained by the reaction into a first reactive distillation tower for reaction; s2, reacting the product obtained in the step S1 in a second pre-reactor, and introducing the product into a second reactive distillation tower for reaction after the reaction is finished; s3, the product obtained in the step S2 and a stabilizer are subjected to a reaction in a mixer, the stabilizer is a nitrogen-containing alkaline compound, lone pair electrons exist on N atoms, and the catalyst is selected from one or two or more of sulfuric acid, nitric acid, isopolyacid and heteropolyacid. By adopting the method to prepare the peroxy acid solution, the selectivity and yield of peroxy acid can be improved, and the total conversion rate of hydrogen peroxide is gt; the selectivity of peroxy acid is gt; meanwhile, caprolactone is prepared by using the peroxy acid to dissolve cyclohexanone oxide liquid, and the conversion rate of cyclohexanone is gt; the selectivity of the obtained caprolactone is gt; 85%.

The invention discloses application of a histone acetyltransferase inhibitor in preparation of a medicine for improving liver fatty degeneration. The invention discloses application of a histone acetyltransferase inhibitor for selectively inhibiting Gcn5 acetylation of histone H3 in preparation of drugs for treating and / or preventing diseases caused by liver fatty degeneration. And the histone acetyltransferase inhibitor for selectively inhibiting acetylation of Gcn5 on histone H3 is CPTH2. The compound CPTH2 reduces the protein abundance of a liver lipid synthesis transcription factor SREBP1c by inhibiting the acetylation activity of H3K9 and H3K14, and obviously improves the liver fatty degeneration of C57BL / 6J mice fed with high fat diet.

The invention discloses a pectin methylesterase gene participating in low-methyl-esterification pectin generation, the pectin methylesterase gene participates in low-methyl-esterification pectin generation during loquat storage, and the nucleotide sequence of the pectin methylesterase gene is shown as SEQ ID No.1. The invention also discloses a preparation method of the pectin methylesterase gene. The method can regulate and control the synthesis of the low-methyl-esterification pectin in the loquat fruits, so that the hardness of the loquat fruits is influenced.

The invention discloses a tRNA (transfer ribonucleic acid) derivative fragment and provides a potential functional application of the tRNA derivative fragment in DKD. And a tRNA derivative fragment, the tRNA derivative fragment is tRF3-IleAAT, and the nucleotide sequence of the tRNA derivative fragment is SEQ ID No. 1. The invention discloses an application of tRF3-IleAAT in preparation of a medicine for treating diabetic nephropathy and an application of a preparation for detecting the expression quantity of tRNA derived fragments in preparation of a diagnostic reagent for diagnosing diabetic nephropathy. According to the research, a new insight is provided for the molecular mechanism of the DKD from the perspective of tRFs and ferroptosis deposition, and a theoretical basis is provided for clinical diagnosis and treatment of the DKD.

This invention discloses the application of a branched-chain amino acid (BCAA) restricted diet in the preparation of drugs for treating liver metastases of tumors. Through mouse model experiments, this invention found that restricting the intake of BCAAs (valine, isoleucine, and leucine) in the diet, or using the SCD1 inhibitor A939572, can significantly inhibit liver metastases of tumors, especially pancreatic cancer liver metastases. Experimental results show that a BCAA restricted diet or SCD1 inhibitor can reduce the number and volume of liver metastases and inhibit their growth. This invention also reveals its mechanism of action: BCAA restriction reduces the propionylation modification of SREBP1, downregulates the transcriptional expression of its target gene SCD1, and thus reduces lipid synthesis, thereby exerting an anti-tumor liver metastasis effect. This invention provides a novel dietary intervention strategy and drug target for the treatment of liver metastases of tumors.

This invention relates to a lipid-lowering synbiotic, its preparation method, and its application, belonging to the field of egg-laying hen farming technology. The lipid-lowering synbiotic of this invention comprises the following components in parts by weight: 3-85 parts of traditional Chinese medicine extract, 1-25 parts of probiotics, 3-30 parts of prebiotics, 1-16 parts of enzyme preparation, and 4-55 parts of dietary therapy components. This synbiotic not only significantly improves the lipid metabolism of laying hens but also significantly prolongs the peak egg-laying period, increases the egg production rate, reduces cholesterol content in egg yolks, promotes calcium and phosphorus absorption, and reduces the paralysis rate in laying hens. It comprehensively improves the economic benefits of egg-laying hen farming.

The application discloses a fluoride nanocomposite and a preparation method thereof in the field of battery material preparation. A manganese source and a cobalt source are dissolved in deionized water, a reducing alcohol aqueous solution is added, and a bimetallic ion oxide precursor material is obtained through a hydrothermal reaction; then, sodium chloride, the bimetallic ion oxide precursor material and an organic carbon source are dissolved in deionized water, freeze-drying is performed, calcination is performed in an inert atmosphere, the sodium chloride is washed clean with deionized water, and then placed in a reaction container; a fluorination reaction is performed with a fluorine source gas under high-temperature conditions, and after natural cooling to room temperature, the nanocomposite with a bimetallic oxide as an inner core, a metal fluoride as an intermediate layer and an outer fluoride layer is obtained. The method realizes synchronous compatibility improvement of a voltage platform, a conductive layer and an active capacity of a fluorinated carbon material, and the nanometer structure shortens the lithium ion migration path and increases the reaction active sites, so that the voltage platform, the energy density and the power output performance of the fluorinated carbon battery are effectively improved.

The invention provides application of RHPS4 in inhibiting monascus to produce citrinin, a biological agent and application of the biological agent, and belongs to the technical field of microbial fermentation. The invention discloses an application of RHPS4 in inhibiting production of citrinin from monascus, the RHPS4 is named as 3, 11-difluoro-6, 8, 13-trimethyl-8H-quinolo [4, 3, 2-kl] acridine onium methyl sulfate salt, the RHPS4 can reduce citrinin synthesized in the growth process of monascus, when co-fermentation culture is carried out to the tenth day, the concentration of the RHPS4 is 5 [mu] mol / L, detection finds that the citrinin is reduced by 99.7%, and the content of citrinin is reduced by 99.7%. The synthesis of citrinin is effectively inhibited. According to the method, RHPS4 and monascus are co-cultured, so that the content of citrinin is reduced, and popularization and application of monascus products are promoted.

The invention discloses yoghourt capable of assisting in reducing uric acid and a preparation method of the yoghourt. The yoghourt is prepared from the following raw materials: 700-900 parts of skim milk, 150-200 parts of pomegranate juice, 50-80 parts of erythritol, 10-50 parts of modified starch, 10-20 parts of bean flour and 10-20 parts of whey protein powder, and the dosage of a leavening agent in every 1000 kg of the raw materials is 50-200 U. All the selected components have a certain uric acid reducing effect and have a synergistic effect, and the whey protein powder and the modified starch are beneficial for improving competitive nucleoside absorption of probiotics and intestinal epithelial cells and reducing purine absorption; polyphenol in the pomegranate juice and ketone substances in the bean flour synergistically improve the oxidation resistance of polar substances, inhibit the activity of xanthine oxidase and reduce the synthesis of uric acid in the body; the bean flour, the pomegranate juice, the whey protein powder and the modified starch are beneficial to promoting the probiotics to repair intestinal barriers and relieve inflammation, so that the expression of uric acid transporter protein is facilitated, the discharge of uric acid is accelerated, and the effect of the probiotic flavored fermented milk on the aspect of reducing uric acid is comprehensively improved.

The invention discloses an n-type semiconductor constructed by quinone synergistic imide and a preparation method and application thereof, a polymer semiconductor material is obtained by polymerization of a quinone-imide compound, and the obtained polymer semiconductor material is used for constructing the n-type semiconductor; according to the invention, a quinonoid compound is embedded into an imide structure, so that the whole molecular structure has excellent solubility, good planarity and strong electron deficiency characteristic. Therefore, the prepared n-type polymer semiconductor has good performance and shows superexcellent application potential in the fields of organic solar cells, organic field effect transistors, organic thermoelectricity and the like.

The invention relates to a robot voice configuration method, electronic equipment and a storage medium, the method is applied to a robot, the method comprises the following steps: determining whether there is second text data identical to first text data in a plurality of text data locally stored by the robot, the first text data being text data of a to-be-generated voice file; when the second text data does not exist, sending the first text data to a cloud, so that the cloud generates a corresponding target voice file based on the first text data after receiving the first text data; and receiving the target voice file sent by the cloud, and completing voice configuration of the robot based on the target voice file. According to the method, generation of repeated voice files is reduced by determining whether the robot locally has reusable voice files or not, and after it is determined that the voice files need to be generated, the voice files are generated by using the cloud, so that excessive local storage and computing resources of the robot are not occupied, the voice synthesis cost is reduced, and the voice synthesis efficiency is improved.

The invention belongs to the technical field of genetically engineered bacteria and microbial fermentation, and particularly relates to a keto-alcohol acid reductoisomerase mutant, high-yield D-pantothenic acid bacteria and application, keto-alcohol acid reductoisomerase mutant is obtained by performing site-specific mutagenesis on 71st, 110th and / or 417th sites of keto-alcohol acid reductoisomerase, and the site-specific mutagenesis mode is that the 71st site is mutated into N, Q or Y from A, the 110th site is mutated into Y or R from Q, and the 71st site is mutated into N, Q or Y from R; the 417th site is mutated from A to Q, Y or R; the sequence of the keto-alcohol acid reductoisomerase is SEQ ID NO. 47; the production capacity of D-pantothenic acid is improved.

The invention discloses a viable bacterium super-poly-selenium composition for inhibiting growth and division of cancer cells, the composition is obtained by compounding viable bacteria and super-poly-selenium, the activity of pkc in tumor cells can be inhibited through selenium, and meanwhile, the growth and proliferation of the tumor cells can be inhibited; the tumor inhibition mechanism of selenium is to induce the change of cell circulating protein, prevent the forward continuous division of cell cycle G1 / S and reduce the DNA synthesis, and methyl selenocysteine in selenium can reduce the activity of cell circulating protein kinase edk2, so that cell differentiation cannot pass through the S phase, thereby inhibiting the cell growth. After the viable bacterium-bifidobacterium is applied to a human body, the viable bacterium-bifidobacterium can balance in-vivo flora imbalance, such as oncogenes generated under the conditions of excessive antibiotics, radiotherapy, chemotherapy or emotion depression and the like, has the effects of assisting the human body in absorbing selenium and balancing human flora, and has a crucial effect on selenium absorption of the human body.

The invention relates to a whitening polypeptide composition and a preparation method thereof. The composition comprises polypeptide prepared from streptomyces griseus through a fermentation process, a radix sophorae flavescentis extract, an alpine aster flower extract, glycerol, sodium hyaluronate and a preservative. The preparation method of the polypeptide comprises the following steps: inoculating streptomyces griseus into a culture medium containing trace elements such as trehalose, fish collagen and selenium, culturing under specific conditions, and performing centrifugation and ultrafiltration separation to obtain the polypeptide with the molecular weight of 500-2000Da. The composition can effectively integrate the whitening and skin care effects of various plant extracts, and a novel skin whitening solution is provided through the unique component proportion and preparation process of the composition.

The invention discloses compact anti-wrinkle elastin peptide freeze-dried powder and a preparation method thereof, and belongs to the technical field of bioactive peptides. The freeze-dried powder is prepared by taking core tubes and / or throat tubes of bred animals as raw materials through cleaning and impurity removal, crushing and homogenizing, degreasing and impurity removal, composite enzymolysis, enzymolysis inactivation, centrifugal separation, gradient filtration, concentration, sterilization and vacuum freeze drying, and has remarkable elastinase inhibitory activity and tightening and anti-wrinkle effects. The livestock and poultry slaughtering byproducts which are wide in source and low in cost are selected as raw materials, high-value utilization of the livestock and poultry slaughtering byproducts is achieved, the optimized preparation technology solves the problems that in the prior art, enzymolysis efficiency is low, product purity is low, activity is insufficient, and stability is poor, the technology is simple, large-scale production is easy, and the method can be widely applied to the fields of cosmetics, food and health care products.

The invention belongs to the technical field of cosmetics, and particularly relates to anti-wrinkle essence water and a preparation method thereof.The anti-wrinkle essence water is mainly capable of achieving the anti-wrinkle and skin care effects due to combination of multiple anti-wrinkle components in the anti-wrinkle essence water, the anti-wrinkle essence water has the effects of promoting skin metabolism, resisting oxidation and reducing inflammation due to matching of the different components in the anti-wrinkle essence water, and the anti-wrinkle essence water is free of side effects. The composition promotes synthesis of collagen by enhancing metabolism and promoting cell regeneration so as to improve skin laxity and wrinkles, improve skin compactness and achieve an anti-aging effect, reduces formation of fine wrinkles and wrinkles by resisting oxidation and neutralizing free radicals, reduces skin inflammation, regulates skin micro-ecology and slows down skin aging by resisting inflammation, and has a good anti-aging effect. In addition, the anti-wrinkle essence water also contains a plurality of moisturizing and soothing components, and the anti-wrinkle, moisturizing and soothing effects are mutually combined and mutually promoted.

The invention provides a composition with a whitening effect as well as a preparation method and application thereof. The composition comprises the following raw materials in percentage by mass: 2-10% of polyhydric alcohol; 2-15% of grease; 0.1-1% of a thickening agent; 0.1-2% of an emulsifier; 1-5% of nicotinamide; 0-3% of 3-o-ethyl ascorbic acid; 0 to 0.4 percent of phenylethyl resorcinol; 0 to 1% of alpha-arbutin; 0-0.5% of a plant whitening compound II; 10% to 0.5% of nonapeptide-10%; 0 to 0.5% of tocopheryl acetate; 0 to 0.5 percent of inositol; 0-0.5% of a purslane extract; 0 to 0.5 percent of bisabolol; and the balance water. According to the composition with the whitening effect, through synergistic interaction of multiple components, the whitening effect is good, and meanwhile, the composition has the anti-allergy and soothing effects.

A novel non-Saccharomyces cerevisiae strain and its application in plum wine fermentation belongs to the field of microbial fermentation technology. The strain is *Pichia kudrica*. Pichia kudriavzevii SWU-PL21, deposited at the Guangdong Provincial Microbial Culture Collection Center (GDMCC No: 68253) on May 12, 2026, exhibits the following pectinase activity: 201.98 ± 7.38 U / mL; PME: 0.8 ± 0.0 U / mL; and tanninase activity: 27.53 ± 0.57 U / mL. In the fermentation of plums with skin, SWU-PL21 improved the alcohol yield and clarity. Sequential inoculation of SWU-PL21 with *Saccharomyces cerevisiae* promoted the formation and accumulation of fruit, floral, and sweet aroma compounds during plum fermentation, and increased the content of total phenols and total flavonoids.