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A heat-sensitive warm water gel and double-sided transparent film color-changing antipyretic patch

A heat sensitive and thermal discoloration technology, applied in the direction of sensors, diagnostic recording/measurement, diagnosis, etc., can solve the problem of sensitive discoloration

Active Publication Date: 2020-07-07
武汉南雪药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to solve the technical problem that the antipyretic patch can visually observe the fever and antipyretic situation, and is sensitive to discoloration within the temperature range of the human body, the present invention provides a heat-sensitive warm water gel and a double-sided transparent film color-changing antipyretic patch. The prepared double-sided transparent antipyretic stickers can be peeled off when in use, leaving only the temperature-sensitive hydrogel and the reinforced grid cloth in the middle, or only one side is torn off, and the other side is the antipyretic. Porous PET film or perforated embossed film can visually observe the fever and fever, and has very good air permeability. When the body temperature is above 38 degrees, the color of the gel layer will fade and become colorless. When the body temperature drops below 37 degrees, the color will return to the technical effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Example 1 A double-sided transparent film discoloration and antipyretic sticker

[0030] A heat-sensitive warm water gel comprising the following raw materials in parts by weight: 5 parts of glycerin, 0.5 parts of sodium polyacrylate, 0.05 parts of aluminum glycolate, 0.01 part of titanium dioxide, 0.01 part of Genma BP, and 0.01 part of thermochromic microcapsule resin , 0.01 part of mint, 20 parts of water.

[0031] The heat-sensitive color-changing microcapsule resin is prepared by the following steps:

[0032] (1) Preparation of thermochromic compound: mix crystal violet lactone, stearyl alcohol, gelatin, and rosin in a mass ratio of 1:4:8:10, take 5g of the mixture, melt it at 60°C, and cool it to 50°C ℃, add 20ml acetone, 20ml ethanol, stir evenly, add 20ml water, 0.5g ethyl acetate, 3g triethylamine, add to a four-necked flask with a condensing device, stir and mix, adjust the pH of the reaction system with sodium hydroxide to 6.5, while heating to 60°C, and ke...

Embodiment 2

[0042] Example 2 A double-sided transparent film discoloration and antipyretic sticker

[0043] A thermosensitive warm water gel comprising the following raw materials in parts by weight: 25 parts of glycerin; 10 parts of sodium polyacrylate; 2 parts of aluminum glycolate; 2 parts of titanium dioxide; 3 parts of Genma BP; 2 parts of thermochromic microcapsule resin ; Mint 1 part, water 65 parts.

[0044] The heat-sensitive color-changing microcapsule resin is prepared by the following steps:

[0045] (1) Preparation of thermochromic compound: mix crystal violet lactone, stearyl alcohol, gelatin, and rosin in a mass ratio of 1.5:4.5:8.5:11, take 8g of the mixture, melt it at 70°C, and cool it to 60°C ℃, add 50ml acetone, 40ml ethanol, stir evenly, add 40ml water, 3g ethyl acetate, 5g triethylamine, add to the four-necked flask with condensing device, stir and mix, adjust the pH of the reaction system with sodium hydroxide to 7.5, simultaneously heating up to 70°C, and keeping...

Embodiment 3

[0056] Example 3 A double-sided transparent film discoloration and antipyretic sticker

[0057] A heat-sensitive warm water gel contains the following raw materials in parts by weight: 50 parts of glycerin, 30 parts of sodium polyacrylate, 10 parts of aluminum glycolate, 10 parts of titanium dioxide, 20 parts of Genma BP, 30 parts of thermochromic microcapsule resin, 15 parts of mint, 100 parts of water.

[0058] The heat-sensitive color-changing microcapsule resin is prepared by the following steps:

[0059] (1) Preparation of thermochromic compound: mix crystal violet lactone, stearyl alcohol, gelatin, and rosin in a mass ratio of 2:5:9:12, take 10g of the mixture, melt it at 80°C, and cool it to 70°C ℃, add 60ml acetone, 60ml ethanol, after stirring evenly, add 60ml water, 4g ethyl acetate, 6g triethylamine, add in the four-neck flask with condensing device, stir and mix, adjust the pH of the reaction system to 8. Simultaneously heat up to 80°C and keep the temperature fo...

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Abstract

The invention discloses a heat-sensitive temperature-sensing hydrogel and a double-sided transparent film change-color fever cooling patch. The heat-sensitive temperature-sensing hydrogel comprises the following raw materials in parts by weight: 5 to 50 parts of glycerin, 0.5 to 30 parts of sodium polyacrylate, 0.05 to 10 parts of dihydroxyaluminum aminoacetate, 0.01 to 10 parts of titanium dioxide, 0.01 to 20 parts of SupGuard GM-BP, 0.01 to 30 parts of thermochromic microcapsule resin, 0.01 to 15 parts of mint and 20 to 100 parts of water. The heat-sensitive temperature-sensing hydrogel is sensitive in color change within the temperature range of the human body, the double-sided transparent film change-color fever cooling patch prepared by the heat-sensitive temperature-sensing hydrogelis sensitive in color change within the temperature range of the human body, and has good air breathability, and fever cooling conditions can be visually observed.

Description

technical field [0001] The invention relates to a thermosensitive warm water gel and a double-sided transparent film discoloration and antipyretic patch. Background technique [0002] At present, antipyretic patch products have been accepted by more and more people in our country by virtue of their practicability and convenience. The antipyretic patch plays a cooling role mainly because it contains polymer hydrogel, which can concentrate heat into the jelly by using physical principles, and quickly evaporate the water in the gel to take away the heat in the body. In addition, some natural medicines contained in antipyretic patches, such as mint and borneol, also have a certain cooling and cooling effect. When a child has a fever, just stick a piece on the forehead or other parts where the large blood vessels run, and the effect of physical cooling can be achieved, and it has become a regular cooling product at home. [0003] There are also color-changing antipyretic sticke...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08L33/02C08L89/00C08L93/04C08L29/04C08K13/02C08K5/053C08K3/22C08K5/05C08J3/075A61B5/01
CPCA61B5/01C08J3/075C08J2333/02C08J2429/04C08J2489/00C08J2493/04C08K5/05C08K5/053C08K13/02C08K2003/2241
Inventor 汪忠汉
Owner 武汉南雪药业有限公司
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