The invention discloses a high-flame-retardation chloroprene rubber sealing gasket. The sealing gasket comprises the following raw materials, by weight, 135-145 parts of chloroprene rubber CR121, 10-15 parts of butyl rubber CBK139, 20-25 parts of chlorhydrin rubber H75, 10-20 parts of an SG-5 PVC resin, 3-5 parts of tri(2-ethylhexyl)acetocitrate, 3-5 parts of di(2-ethylhexyl)-4,5-epoxy tetrahydrophthalate and 1-2 parts of propylene glycol sebacate. The sealing gasket has the advantages of good high temperature resistance, good sealing performance, flame retardation grade reaching UL94-V0 or higher, good corrosion resistance, realization of long-term working in mediums comprising acids, alkalis, oil and the like, small volume and hardness changes, no adhesion on the metal surface, small friction coefficient, good abrasion resistance, good combination flexibility with a sealing surface, good weather ageing and ozone ageing resistances, durability and the like.