1110 results about "Safflowers" patented technology

The invention relates to the technical field of traditional Chinese medicine, in particular to a Mongolian medicine tea drink for relieving respiratory system abnormality and a preparation method and application thereof.The Mongolian medicine tea drink is prepared from rhododendron micranthum, pomegranate, amomum cardamomum, long pepper, cinnamon, safflower, agilawood, clove, myristica fragrans, fructus choerospondiatis, bistort rhizome, liquorice, tabasheer, radix aucklandiae, white raisin and crabs. The processed products of the Mongolian medicine components are weighed according to the formula dosage, then ground into coarse powder and bagged to prepare tea bags. The Mongolian medicine tea drink provided by the invention has the effects of moving Heli, relieving cough, reducing phlegm and diminishing swelling; the traditional Chinese medicine composition can be used for treating the symptoms such as' Bada dry Hiri 'dizziness, asthma, chronic bronchitis, indigestion disease, edema, edema and water tympanites.

The invention provides a traditional Chinese medicine gel patch for treating gouty arthritis and a preparation method thereof. The traditional Chinese medicine gel patch for treating gouty arthritis comprises at least a gel layer loaded with traditional Chinese medicine extracts; the traditional Chinese medicine extracts comprise the following raw materials: coix seed, phellodendron amurense, clematis root, radix scutellariae, atractylodes lancea, radix ophiopogonis, radix scutellariae, acer scutellariae, radix scutellariae, radix aconiti kusnezoffii, radix strychnii, frankincense, myrrh, angelica sinensis, safflower, cyathula root, radix paeoniae rubra, radix smilacis gracile, radix striatae, eucalyptus glomeratae, sophora flavescens, andrographis paniculatae, radix lobeliae, rhizoma coptidis, radix scutellariae, cassia twig, zanthoxylum bungeanum, and borneol; and a matrix of the gel layer comprises the following raw materials in parts by weight: silk fibroin, polyvinyl pyrrolidone, azido-polyethylene glycol-carboxylic acid, 1-ethynylcyclopropylcarboxylic acid, 2,5-dicarboxylic acid-3,4-ethylenedioxythiophene, and glycerol. The traditional Chinese medicine gel plaster of the present invention can achieve good therapeutic effects through percutaneous absorption.

The invention discloses a traditional Chinese medicine composition for soothing liver-qi stagnation, softening hard mass and dissolving phlegm and a preparation method thereof, and particularly relates to the technical field of traditional Chinese medicines. Comprising the following components: roasted rhizoma atractylodis macrocephalae, angelica sinensis, cortex moutan, peach kernels, raw oyster shells, rhizoma sparganii, radix curcumae, spina gleditsiae, rhizoma acori graminei, rhizoma bolbostemmae, immature bitter oranges, selfheal, roses, lindera aggregata leaves, prepared arisaema consanguineum schott, fructus liquidambaris, orange peels, feverfew, hawksbill flowers, paeonia ostii flowers, exocarpium citri rubrum, mulberries, fructus lycii, flos caryophylli, fingered citron, rosemary, jasmine flowers, saffron, mulberry leaves, dandelions, gorse, kumquats, radix fici simplicissimae, purple perilla and mint. The traditional Chinese medicine composition has multiple effects of soothing the liver, promoting the circulation of qi, softening hardness to dissipate stagnation, tonifying the spleen, reducing phlegm, activating blood and clearing heat, gives consideration to overall conditioning and target treatment, and contains medicinal and edible components, so that the safety is improved. According to the preparation method, the processes of segmented decoction, vacuum low-temperature concentration, high-pressure homogenization and pasteurization are adopted, so that sufficient extraction and retention of effective components are ensured, and the curative effects of soothing liver-qi stagnation, softening hard mass and dissolving phlegm are remarkably improved.

The invention discloses a raw material treatment device and method for producing a new-formula saffron fluid extract, and relates to the technical field of crushing devices. Comprising a support, a mounting shell is fixedly connected to the support, a discharging opening is formed in the lower side of the mounting shell, the mounting shell is provided with a sealing door, and the sealing door is fixedly connected with a material guiding shell communicating with the mounting shell; the plurality of fixed teeth are distributed at intervals and are fixedly connected to the sealing door; and the rotating disc is rotationally connected to the mounting shell, a plurality of moving teeth are fixedly connected to the rotating disc, and symmetrically-distributed cutting edges are slidably connected to the moving teeth. By changing the positions of the cutting edges, fibers wound on the adjacent moving teeth are cut by the cutting edges, so that materials wrapped by fiber materials are exposed, the cut fibers and the materials fall into the mounting shell again, the material crushing speed is increased, the material crushing duration is shortened, and the crushing efficiency is improved.

The invention discloses a traditional Chinese medicine composition for preventing / treating systemic lupus erythematosus and application thereof.The traditional Chinese medicine composition is reasonably combined according to etiology and pathogenesis of systemic lupus erythematosus, pseudo-ginseng, ginseng, glossy privet fruit and syngnathus serve as monarch drugs, and the traditional Chinese medicine composition has the effects of promoting blood circulation to remove blood stasis, nourishing the liver and tonifying the kidney and directly tonifying yin deficiency of the liver and the kidney; salvia miltiorrhiza, safflower, peach kernel, American ginseng, codonopsis pilosula, prepared rhizome of rehmannia, wolfberry, mulberry and panax japonicus are taken as ministerial drugs and are matched to assist the monarch drugs and clear stasis heat, cornu cervi pantotrichum, herba epimedii, hippocampus, pericarpium citri reticulatae, polygonum multiflorum, angelica sinensis, radix paeoniae alba, rhizoma polygonati and dog kidney are taken as adjuvant and conductant drugs and assist the monarch and ministerial drugs to harmonize yin and yang, all the drugs are matched and have a synergistic effect, and the effects of nourishing kidney and replenishing essence, reinforcing qi and nourishing yin, promoting blood circulation to remove meridian obstruction, warming yang and removing stasis can be achieved. The traditional Chinese medicine can treat both symptoms and root causes, and can effectively treat systemic lupus erythematosus.

The invention discloses a traditional Chinese medicine composition for treating skin diseases and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 6-12 parts of radix notoginseng, 8-15 parts of radix salviae miltiorrhizae, 10-20 parts of rhizoma chuanxiong, 8-15 parts of rhizoma curcumae longae, 15-35 parts of radix angelicae sinensis, 3-8 parts of sandalwood, 3-8 parts of fructus aurantii immaturus, 40-60 parts of ramulus cinnamomi, 8-15 parts of rhizoma corydalis, 8-15 parts of rhizoma curcumae, 2-5 parts of flos carthami, 5-12 parts of radix puerariae, 8-15 parts of radix rehmanniae, 3-8 parts of pericarpium citri reticulatae and 8-15 parts of spica prunellae. The traditional Chinese medicine composition is prepared from 3-8 parts of radix trichosanthis, 15-35 parts of tribulus terrestris, 15-35 parts of cicada slough, 5-12 parts of stiff silkworm and 8-15 parts of rhizoma drynariae. According to a multi-target collaborative mechanism, network pharmacology proves that 12 pathological pathways such as IL-17A and the like can be regulated and controlled, and the TNF-alpha inhibition rate is 89% and the barrier repair speed is increased by 2.3 times through key component combination. According to a transdermal synergistic technology, the specific surface area of the medicine reaches 8.5 m < 2 > / g through superfine grinding, a Franz test shows that the penetration amount of tanshinone is increased by 3.7 times, and the onset time is shortened to 8.3 minutes. Dual scar regulation and control: the thickness of scars in 12 weeks is reduced by half through TGF-beta3 up-regulation and alpha-SMA inhibition, and the collagen order degree is improved by 3.2 times.

The invention relates to the technical field of traditional Chinese medicine pharmacy, and discloses a traditional Chinese medicine micro-powder capsule based on functions of promoting blood circulation to remove blood stasis, dispelling wind and eliminating dampness and activating meridians to stop pain. 0.8%-1.2% of scorpion; 0.8%-1.2% of Chinese polyphaga; 0.8%-1.2% of safflower carthamus; 0.8%-1.2% of peach kernels; 0.8%-1.2% of zaocys dhumnade; 0.8% to 1.2% of frankincense; 0.8%-1.2% of ligusticum wallichii; 0.8%-1.2% of cortex moutan; 0.8% to 1.2% of myrrh; 0.8%-1.2% of notopterygium root; 0.8%-1.2% of radix angelicae pubescentis; 0.8%-1.2% of fructus lycii; 0.8%-1.2% of centipede; 15%-25% of a functional auxiliary material: 3%-5% of a nano dispersion carrier; and 3%-5% of an inclusion compound. By adopting a beta-cyclodextrin inclusion technology, volatile oil and a humid and hot environment can be effectively isolated, the stability of the volatile oil can be enhanced, by taking ligustrazine as an example, under an accelerated test condition, the retention rate of the ligustrazine in 6 months is up to 89.5%, and compared with a non-inclusion condition, the retention rate is improved, the degradation rate is reduced by 3.1 times, and the stability of the core component for promoting blood circulation to remove blood stasis in the storage and use process is ensured.

The invention provides a safflower pigment extraction method. The safflower pigment extraction method comprises the following steps: preparing a safflower decoction; adding whey protein into the safflower boiling liquid, and uniformly stirring; standing for layering, removing supernatant liquid, and then regulating and controlling the pH value of the mixed liquid; selective separation of carthamin yellow and haematochrome is realized through pH control; wherein yellow pigment mud is obtained under the alkaline condition, and red pigment mud is obtained under the acidic condition; the obtained yellow pigment mud and the obtained red pigment mud are subjected to vacuum drying and then ground, and the drying temperature is 30-40 DEG C. According to the safflower pigment extraction method provided by the invention, the selective separation of safflower yellow / red pigment is realized by regulating the pH value, and the limitation of single pigment extraction is broken through; and the weather resistance of the product is effectively improved through low-temperature grinding and a color fixing agent compounding and coating process. The invention further provides application of the safflower pigment.

The invention relates to a traditional Chinese medicine composition for treating ischemic stroke and a method and application thereof, and belongs to the technical field of traditional Chinese medicines. The invention discloses a traditional Chinese medicine composition for treating ischemic stroke. The traditional Chinese medicine composition is prepared from the following raw materials: ginseng, pseudo-ginseng, radix polygoni multiflori preparata, ligusticum wallichii, safflower carthamus, salvia miltiorrhiza, hawthorn, loranthus parasiticus, longspur epimedium, radix puerariae, cornu bubali, ginseng leaves, rhizoma acori graminei and borneol. According to the preparation method disclosed by the invention, the ligusticum wallichii and compound bacteria consisting of lactobacillus plantarum, bacillus subtilis and coriolus hirsutus are fermented, so that more laccase and active substances are generated in a fermented product, and then the fermented product is subjected to compound enzyme treatment, so that the processed ligusticum wallichii is better in medicine effect, and the curative effect of the ligusticum wallichii is improved. Therefore, the treatment effect of the traditional Chinese medicine composition for treating ischemic stroke is enhanced, neurological dysfunction caused by cerebral ischemia can be remarkably relieved, and the traditional Chinese medicine composition has a good protection effect on ischemic stroke nerve injury.

The invention relates to a traditional Chinese medicine for treating children autism, which can effectively solve the medication problems of good curative effect and convenience for treating children autism. The preparation method comprises the following steps: disinfecting and sterilizing radix bupleuri, radix paeoniae alba, fructus aurantii, rhizoma nardostachyos, rhizoma atractylodis macrocephalae, poria cocos, codonopsis pilosula, cassia twig, rhizoma acori graminei, cistanche, rhizoma alismatis, peach kernel, safflower, scutellaria baicalensis, pinellia ternate, honey-fried licorice root, rock candy and maltose, soaking, boiling with strong fire, decocting with slow fire, filtering, heating to prepare a traditional Chinese medicine concentrated solution, adding rock candy and maltose, decocting into thick paste, pouring into a mold, shaping at room temperature to form granules, and packaging. The traditional Chinese medicine composition is rich in raw materials, easy to operate in preparation method and scientific and reasonable in compatibility according to the primary and secondary relationship of monarch, minister, assistant and guide, has the effects of soothing the liver, strengthening the spleen, tonifying the kidney, replenishing essence, inducing resuscitation and promoting intelligence, is effectively used for treating autism of children, and has huge economic and social benefits.

The invention relates to the technical field of traditional Chinese medicine compositions, and discloses a traditional Chinese medicine composition for treating cervical spondylotic radiculopathy and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20 to 40 parts of radix puerariae, 5 to 25 parts of cassia twig, 20 to 40 parts of ramulus mori, 5 to 25 parts of notopterygium root, 20 to 40 parts of radix astragali seu hedysari, 20 to 40 parts of radix salviae miltiorrhizae, 5 to 25 parts of rhizoma chuanxiong, 5 to 25 parts of radix angelicae sinensis, 20 to 40 parts of radix paeoniae alba, 5 to 25 parts of radix clematidis, 5 to 20 parts of radix notoginseng, 2 to 10 parts of flos carthami, 5 to 25 parts of fructus chaenomelis lagenariae, 5 to 25 parts of earthworm, 20 to 40 parts of caulis spatholobi and 5 to 25 parts of pericarpium citri reticulatae. The traditional Chinese medicine composition disclosed by the invention is precise and reasonable in formula, standard and feasible in preparation process, free of any hormone, preservative and additive, and high in safety as natural raw materials are selected.

The invention provides an external traditional Chinese medicine composition for treating knee osteoarthritis and a preparation method thereof. The traditional Chinese medicine composition is prepared from Chinese angelica, safflower, pollen typhae, herba schizonepetae, zedoary, radix clematidis, notopterygium root, cortex periplocae, cortex erythrinae, caulis spatholobi, fried szechwan chinaberry fruit, rhizoma smilacis glabrae, salvia miltiorrhiza, pepper, garden balsam stem and prepared kusnezoff monkshood root. The external traditional Chinese medicine composition for treating knee osteoarthritis is reasonable in compatibility of the components, dredges channels and collaterals, activates blood circulation to remove blood stasis, enables qi and blood of tendons and vessels to be smooth, eliminates dampness and coldness, and relieves pain, so that the treatment purpose is achieved.

The invention relates to a traditional Chinese medicine composition for treating or preventing osteoporosis, and discloses application of the traditional Chinese medicine composition in preparation of a medicine for treating and / or preventing osteoporosis. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 22-26 parts of bull penis, 8-12 parts of cinnamon, 10-14 parts of alfalfa seeds, 8-12 parts of galangal, 10-14 parts of onion seeds, 8-12 parts of clove, 10-14 parts of fructus ulmi, 8-12 parts of pepper, 12-16 parts of carrot seeds, 38-46 parts of sesame, 10-14 parts of muskmelon seeds, 56-64 parts of almonds, 10-14 parts of cucumber seeds, 8-12 parts of asarum, 10-14 parts of semen allii tuberosi and 16-20 parts of limonium macrophyllum. The medicine is prepared from the following raw materials in parts by weight: 10-14 parts of dill seeds, 13-17 parts of tribulus terrestris, 36-44 parts of milk peaches, 8-12 parts of mirabilis jalapa roots, 18-22 parts of cotton seeds, 10-14 parts of radix aucklandiae, 10-14 parts of ginger slices, 8-12 parts of nutmeg coats, 46-54 parts of pinus bungeana, 10-14 parts of sesame seeds, 3-7 parts of saffron, 8-12 parts of fern, 8-12 parts of fructus piperis longi and 18-22 parts of nutmeg.

The invention discloses a pharmaceutical composition for preventing and treating chronic atrophic gastritis. The pharmaceutical composition is prepared from the following raw materials in the following weight ratio: 14-18 parts of peach kernel, 10-14 parts of Chuanxiong rhizome, 8-12 parts of Panax notoginseng, 6-10 parts of safflower, 20-28 parts of kelp, 10-14 parts of selfheal, 15-25 parts of codonopsis pilosula, 10-14 parts of atractylodes macrocephala, 12-16 parts of fructus aurantii, 8-12 parts of amomum villosum, 12-16 parts of bupleurum, 10-18 parts of citron, and 5-10 parts of fucoidan. The pharmaceutical composition is used to treat chronic atrophic gastritis of gastric collateral blood stasis type by promoting blood circulation and removing blood stasis, unblocking meridians and relieving pain, eliminating phlegm, softening and dispersing nodules, invigorating qi and promoting qi circulation, and soothing the liver and harmonizing the stomach. The invention also discloses a preparation method of the pharmaceutical composition.

The invention discloses a camellia chekiangoleosa improved variety breeding method and a camellia chekiangoleosa improved variety breeding system based on function superposition, and the method comprises the following steps: cloning excellent single plants through a high-stem grafting technology, and establishing a specific germplasm resource library; determining three types of phenotypic data of a floral leaf character set, an oil yield character set and an oil quality character set; the method comprises the following steps: presetting six types of application scenes such as an edible oil production raw material forest and a specific natural compound production raw material forest, and constructing a comprehensive evaluation model by adopting a hierarchical weight distribution method: distributing first-level weights for three types of character sets, and then distributing second-level weights for characters in subsets; standardizing the character of the floral leaf by adopting a binary comparison method, and standardizing the character of the oil yield and the character of the oil quality by adopting a centesimal system; and screening a target improved variety according to a comparison result of the comprehensive score of the to-be-evaluated variety and the average score of the existing improved variety. By means of the method, superposition breeding of ornamental, oil production and oil quality functions is achieved, and the adaptability of improved varieties and industrial scenes is improved.

The invention discloses an application of a traditional Chinese medicine composition in preparation of a medicine for preventing and treating atherosclerosis combined with hyperhomocysteinemia and / or hyperlipidemia. The traditional Chinese medicine composition comprises the following components: ginseng, lucid ganoderma, safflower, musk, calculus bovis, bear gall, pearl, venenum bufonis, radix aconiti carmichaeli and borneol. According to the traditional Chinese medicine composition disclosed by the invention, through reasonable compatibility of all the components, at least one of indexes such as aorta plaque area, vasomotor inner diameter difference, intima-media thickness, blood fat level, homocysteine content and the like in atherosclerosis combined with hyperhomocysteinemia and / or hyperlipidemia can be effectively improved; the symptoms of atherosclerosis combined with hyperhomocysteinemia and / or hyperlipidemia are relieved from multiple aspects, and the progress of the disease course is blocked. The traditional Chinese medicine composition is controllable in quality, convenient for standardized production, safe and reliable in prescription and free of toxic and side effects on human bodies.

The preparation method comprises the following steps: (1) soaking male silkworm moths in white spirit, extracting, and filtering to obtain a male silkworm moth extracting solution; (2) performing percolation extraction on herba epimedii, semen cuscutae, fructus lycii, cordyceps sinensis, herba cistanche, rhodiola rosea, radix astragali, radix rehmanniae praeparata and stigma croci with white spirit to obtain percolate; (3) combining the male silkworm moth extracting solution and the percolating solution to obtain a medicine extracting solution; and (4) filtering the medicine extracting solution by using a 0.22-1 mu m polypropylene filter membrane, standing for 30-60 days, then filtering by using a 0.22-1 mu m polyethersulfone filter membrane, mixing with rock candy liquid, adjusting the alcohol content to (39 + / -2) degrees, and filtering by using a 0.22-1 mu m polyethersulfone filter membrane to obtain the traditional Chinese medicine wine. The medicinal liquor prepared by the preparation method disclosed by the invention is high in stability, and the problem that precipitates are generated by an original production process is effectively solved.

The invention relates to the technical field of digital twinborn and agricultural information, and discloses a digital twinborn growth simulation and optimization method for safflower seedling breeding, and the method comprises the following steps: constructing individual digital twinborn bodies fusing genotypes, phenotypes and multi-dimensional environmental perception data; performing hybrid modeling in combination with the mechanism model and a depth time sequence neural network, and correcting growth prediction deviation in real time; and based on multi-objective optimization of biomass, medicinal component content and water efficiency, generating a precise cultivation regulation and control instruction. The system comprises a data acquisition unit, a twin construction unit, an environment fusion unit, a hybrid modeling unit, a visualization unit, an optimization decision unit and an instruction execution unit. According to the method, through closed-loop intelligent regulation and control, the yield, quality and resource utilization efficiency of safflower seedling breeding are remarkably improved.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to application of a traditional Chinese medicine composition in preparation of anti-hepatoma medicines. The traditional Chinese medicine composition comprises red ginseng, ox horn tip, musk, borneol, safflower, bezoar, radix aconiti lateralis praeparata slice, venenum bufonis, pseudo-ginseng, benzoin and pearl. Experimental results show that the traditional Chinese medicine composition can induce apoptosis and necrosis of liver cancer cells and inhibit proliferation of the liver cancer cells; and liver cancer cells are retarded to be in a G1 cell cycle. Therefore, the invention provides a new therapeutic drug for clinical treatment of liver cancer, and the raw materials are natural medicinal materials, have wide sources and have good application prospects.

The invention relates to the technical field of beauty and health care, and discloses a traditional Chinese medicine composition for whitening adult women, which comprises the following raw materials by weight: 10-15% of dahurian angelica root, 10-15% of bighead atractylodes rhizome, 10-15% of Poria cocos, 5-10% of pearl powder, 8-12% of Chinese angelica, 3-5% of licorice, 5-8% of safflower, 5-8% of wolfberry, 8-12% of Chinese yam and 10-15% of coix seed. According to the traditional Chinese medicine composition for whitening the adult females and the preparation method of the traditional Chinese medicine composition, multiple traditional Chinese medicinal materials with multiple effects of whitening, removing freckles, resisting oxidation, moisturizing and the like, such as radix angelicae, rhizoma atractylodis macrocephalae, pearl powder, radix angelicae sinensis and the like are adopted, and through scientific compatibility and proportion, the traditional Chinese medicinal materials can achieve a synergistic effect from multiple aspects, so that a comprehensive whitening effect is achieved; the skin care composition has the advantages that the skin care composition has anti-aging and moisturizing functions at the same time, comprehensive skin care is provided for users, pure natural traditional Chinese medicine components are selected, chemical whitening agents, essence and preservatives are not contained, irritation and side effects are effectively reduced, and the skin care composition is suitable for all skin types, especially adult women with sensitive skin, and milder whitening experience is provided.

The present invention discloses a traditional Chinese medicine composition for treating dry eye and a preparation method thereof. The traditional Chinese medicine composition for treating dry eye is made from the following components in parts by weight: 10-12 parts of Chinese wolfberry, 5-10 parts of chrysanthemum, 10-15 parts of cassia seed, 10-12 parts of cortex fraxini, 5-10 parts of safflower, and 10-12 parts of phellodendron amurense. The traditional Chinese medicine composition for treating dry eye prepared by this method has less dosage, is convenient to use, safe and without side effects when treating dry eye, and has a significant therapeutic effect in aspects such as prolonging the breakup of the tear film, increasing the tear flow rate, and improving corneal staining, and can be promoted as a drug for treating dry eye.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a blood-activating and detoxifying traditional Chinese medicine formula and a nanogel preparation method thereof. The invention provides a traditional Chinese medicine formula for promoting blood circulation and removing toxicity and a nanogel preparation method of the traditional Chinese medicine formula for promoting blood circulation and removing toxicity to solve the problem that in the prior art, a good external application traditional Chinese medicine formula capable of being used for skin with damp-heat toxin accumulation does not exist, and the traditional Chinese medicine formula for promoting blood circulation and removing toxicity and the nanogel preparation method of the traditional Chinese medicine formula for promoting blood circulation and removing toxicity comprise monarch drugs, ministerial drugs, adjuvant drugs and conductant drugs, the ministerial drugs comprise honeysuckle flowers, fructus forsythiae, paris polyphylla, cortex dictamni and fructus kochiae, the adjuvant drugs comprise radix salviae miltiorrhizae, flos carthami, garden balsam stems and centella asiatica, and the conductant drug comprises bletilla striata. The traditional Chinese medicine composition provided by the invention is precise and appropriate in compatibility and distinct in gradation, and can form a synergistic treatment chain of clearing heat, detoxifying, activating blood and promoting tissue regeneration, so that the wound healing speed of the skin surface is accelerated, and the traditional Chinese medicine composition has a relatively good curative effect on damp-heat and toxic stasis type skin diseases.

The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for relieving xerophthalmia and asthenopia and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 40 to 50 parts of herba equiseti hiemalis, 30 to 40 parts of rhizoma chuanxiong, 15 to 35 parts of radix codonopsis, 20 to 25 parts of white chrysanthemum flower, 5 to 8 parts of flos carthami, 10 to 15 parts of semen celosiae, 10 to 20 parts of cortex phellodendri, 5 to 15 parts of folium artemisiae argyi, 3 to 5 parts of herba portulacae, 15 to 25 parts of herba albiziae, 0.5 to 1 part of menthol, 0.5 to 1 part of borneol and 1 to 2 parts of deep sea whole algae extract. The traditional Chinese medicine composition can effectively relieve xerophthalmia and asthenopia, and potential complication risks can be avoided.

The invention discloses an external composition for preventing and relieving joint discomfort. The external composition comprises a pseudo-ginseng extract, a radix ranunculi ternati extract, a geranium graciliforme extract, a safflower extract, a phryma leptostachya extract, an angelica root extract, a radix aconiti agrestis extract, a short-pedicel aconite root extract, an earthworm extract, a corydalis tuber extract, a rhizoma sparganii extract, an achyranthes root extract, a cinnamon extract, a morinda citrifolia extract and a loose knot extract. According to the traditional Chinese medicine composition disclosed by the invention, effective components are induced to directly reach uncomfortable parts of joints through respective channel tropism effects of the composition; symptoms such as numbness and pain can be quickly relieved, functions are adjusted, and rehabilitation is promoted; through test comparison of multiple patients, it is also verified that the external composition can well relieve and prevent the joint discomfort; and the test result has no toxic or side effect.

The invention belongs to the technical field of biological medicines, and particularly relates to an alkali-extracted saffron petal polysaccharide APPCS-1a as well as a preparation method and application thereof. The APPCS-1a provided by the invention is uniform polysaccharide, has the molecular weight of about 40KDa, better thermal stability, no triple helix, more negative charges and good antioxidant activity, and can be applied to preparation of anti-aging medicines, health care products or cosmetics. According to the extraction method of APPCS-1a, an alkali extraction and alcohol precipitation method is adopted, the extracted polysaccharide is rich in uronic acid, good in biological activity and wide in biological application value, and the extraction method is simple, low in cost and suitable for industrial mass production.

The invention discloses a hydrogel patch for promoting blood circulation to remove meridian obstruction and a preparation method thereof. The formula of the hydrogel patch for promoting blood circulation to remove meridian obstruction comprises a traditional Chinese medicine concentrated solution for promoting blood circulation to remove meridian obstruction, an oil-in-water emulsion for promoting blood circulation to remove meridian obstruction, sodium polyacrylate, polyacrylic acid, glycerol, azone, dihydroxyaluminum aminoacetate, tartaric acid, disodium ethylene diamine tetraacetate, methylparaben and deionized water. The traditional Chinese medicine concentrated solution for promoting blood circulation to remove meridian obstruction is 70% ethanol extract of vinegar-processed rhizoma corydalis, ligusticum wallichii, philippine flemingia root, safflower, frankincense, myrrh, radix angelicae and liquorice; the oil-in-water emulsion capable of promoting blood circulation to remove meridian obstruction is prepared from a vinegar rhizoma corydalis sesame oil extract, wintergreen oil, methyl glucose sesquistearate, stearate, cetostearyl alcohol, polydimethylsiloxane and deionized water; the blood-activating collateral-dredging hydrogel patch has no skin irritation, belongs to weak sensitization, and has the function of assisting in relieving pain.

The invention provides a composition with an analgesic effect. The composition is an external medicament prepared from the following raw material medicines in parts by weight: 10-16 parts of teasel root, 2-4 parts of dragon's blood, 8-12 parts of safflower, 9-15 parts of myrrh, 9-15 parts of ligusticum wallichii, 9-15 parts of notopterygium root, 8-12 parts of clove, 8-12 parts of beautiful sweetgum fruit, 0.6-1 part of pepper, 2-4 parts of lucid ganoderma, 0.4-0.8 part of capsaicin and 0.08-0.12 part of musk. The invention also provides a preparation method and application of the composition. The traditional Chinese medicine composition is precise and appropriate in raw material formula compatibility, is used for treating pain, is clear and controllable in medicine effect, and provides a new choice for clinic.

The invention relates to the technical field of traditional Chinese medicine, and discloses a plaster for treating bone fracture and a preparation method thereof, and the plaster comprises the following raw materials: peach kernel, safflower, ligusticum wallichii, radix cyathulae, rhizoma drynariae, radix angelicae pubescentis, notopterygium root, eucommia ulmoides, astragalus membranaceus, pseudo-ginseng, native copper, dragon's blood, catechu, angelica sinensis, radix rehmanniae, gentiana macrophylla, radix saposhnikoviae, earthworm, centipede, scorpion, ground beetle, liquorice, frankincense, myrrh, yellow lead, sesame oil and other auxiliary materials. Pseudo-ginseng is added into the formula, the effects of promoting blood circulation to remove blood stasis, diminishing swelling and relieving pain of pseudo-ginseng are utilized, absorption of blood stasis of the bone fracture part can be accelerated, then pain and swelling caused by blood stasis blocking are remarkably relieved, blood circulation is promoted, and injury repair is promoted, and radix angelicae sinensis and radix rehmanniae are added into the formula, and the effects of replenishing blood and promoting blood circulation of radix angelicae sinensis and nourishing yin and cooling blood of radix rehmanniae are utilized, so that the bone fracture can be cured, and the bone fracture can be cured. And blood generation and local microcirculation improvement can be promoted, so that the blood supply and oxygen supply capacity of a bone fracture repair part is enhanced, and soft tissue repair is accelerated.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine compound for reducing recurrence of chronic nasosinusitis and a preparation method of the traditional Chinese medicine compound, and the traditional Chinese medicine compound is prepared from, by weight, 14-16 g of radix astragali, 8-10 g of fried radix scutellariae, 8-10 g of radix angelicae, 5-7 g of fructus xanthii, 5-7 g of flos magnoliae, 14-16 g of flos chrysanthemi indici, 11-13 g of fried fructus gardeniae, 5-7 g of radix angelicae sinensis, 5-7 g of flos carthami and 8-10 g of herba menthae. The traditional Chinese medicine composition can significantly improve clinical symptoms of patients with chronic nasosinusitis and reduce the recurrence rate, is good in safety, and does not find abnormal symptoms in clinical use. Meanwhile, the preparation process is simple to operate and suitable for industrial mass production. The raw medicinal materials selected by the traditional Chinese medicine composition are synergistic and complementary in nature and effect, inherit the holism concept of traditional Chinese medicine, emphasize that the traditional Chinese medicine composition emphasizes whole body treatment, plays a role together and inhibits infiltration of inflammatory cells while treating local parts, has small toxic and side effects, fully plays the advantages of treating chronic sinusitis and preventing relapse of the traditional Chinese medicine, relieves the pain of patients, and has a remarkable curative effect on treating chronic sinusitis. The life quality of patients is improved and the recurrence probability is reduced.

The invention discloses glycosyltransferase in safflower and a related biological material and application thereof. The invention firstly discloses any one of the following proteins: A1) a protein consisting of an amino acid sequence as shown in a sequence 2; a2) a fusion protein obtained by connecting the N end or / and C end of the protein as shown in the sequence 2 with a protein tag. The invention further discloses the protein related biological material and application thereof. The HSYA biosynthesis key glycosyl transferase gene UGT708U5 is obtained from safflower for the first time, it is proved that the protein UGT708U5 coded by the gene can catalyze phloretin to form HSYA precursor compounds, namely phloretin-mono-C-glucoside and phloretin-di-C-glucoside, and the gene plays an important role in biosynthesis and heterologous production of HSYA; the method has important theoretical and practical significance for regulating and producing the quinonechalcone C-glycoside compounds of plants and cultivating high-quality safflower carthamus.