7 results about "Safflower yellow" patented technology

The invention provides a natural carthamin yellow-beta-cyclodextrin inclusion compound with high stability and a preparation method of the natural carthamin yellow-beta-cyclodextrin inclusion compound, and belongs to the technical field of stable modification of natural pigments. The natural carthamin yellow-beta-cyclodextrin inclusion compound comprises beta-cyclodextrin and natural carthamin yellow, wherein the molecular ratio of the beta-cyclodextrin to the natural carthamin yellow is 1: 1. The preparation method comprises the following steps: dissolving beta-cyclodextrin in water to form a beta-cyclodextrin saturated solution, adding natural carthamin yellow into the beta-cyclodextrin saturated solution, stirring for 1 hour at the temperature of 50 DEG C, and freeze-drying to obtain the natural carthamin yellow-beta-cyclodextrin. According to the natural safflower yellow-beta-cyclodextrin inclusion compound, beta-cyclodextrin serves as a subject, natural safflower yellow serves as an object, and the inclusion compound with the low pigment loss rate and the high light stability is successfully prepared by optimizing three key process parameters including the subject-object molecular ratio, the stirring temperature and the stirring time. The protection effect on the natural carthamin yellow is improved.

The application discloses a kind of shentong zhuyu decoction fingerprint construction method and application, belong to the technical field of drug detection.The application is detected by high performance liquid chromatography to several batches of shentong zhuyu decoction by the selection of mobile phase and the cooperation of chromatographic column, the high performance liquid chromatography of different batches of shentong zhuyu decoction is compared, obtains the common peak containing loganic acid, amygdalin, hydroxyl safflower yellow pigment A, aniseed acid, qianghuo alcohol, isoeucommarin, ammonium glycyrrhizinate, kaempferol characteristic peak, and the fingerprint of shentong zhuyu decoction is constructed according to the common peak.The fingerprint constructed by the application can better detect 12 medicinal materials, shorten the detection time of single sample to 125 min or less, improve efficiency, and improve the quality control level of product.

The invention discloses a characteristic chromatogram for detecting a Yiyouqing particulate matter basis as well as a construction method and application thereof, and belongs to the field of quality control of traditional Chinese medicine compound preparations. According to the method, hydroxysafflor yellow A, rutin, kaempferol-3-O-rutinoside, astragalus smicus glycoside, flatstem milkvetch glycoside and kaempferol are taken as reference substances, multiple batches of samples of the Yiyouqing granules are analyzed by utilizing a high performance liquid chromatography-mass spectrometry technology, and a chemical component characteristic spectrum is established. Compared with a traditional method, the method has good precision and reproducibility, data are accurate and reliable, the six components can be recognized at the same time under the same chromatographic condition, analysis efficiency is greatly improved, synchronous monitoring of multiple components is achieved, and consistency and stability of preparation quality are guaranteed. The method provides support for improving the quality standard of the Yiyouqing granules, and has important significance on the clinical curative effect and medication safety of the Yiyouqing granules.

The invention discloses a method for enhancing the stability of natural carthamin yellow. The method comprises the steps that natural carthamin yellow powder and tea polyphenol are dissolved in water and stirred evenly to obtain a pigment solution, the pigment solution is stored in a dark place at the temperature of 25 DEG C, the mass concentration of natural carthamin yellow in the pigment solution is 0.1%, and the concentration of the tea polyphenol in the pigment solution is 0.1-0.3%. The tea polyphenol has a color protection effect on the natural carthamin yellow, the stability of the natural carthamin yellow can be effectively improved, 0.1% of tea polyphenol has the best color protection effect, and the pigment loss rates are 9.12% and 15.21% respectively after testing for 12 hours under the conditions of strong light irradiation and high temperature of 60 DEG C.

The preparation device comprises a mixing assembly, an environment adjusting assembly is installed at the lower end of the interior of the mixing assembly, a stirring assembly is installed at the upper end of the mixing assembly, a transfer assembly is connected to the upper end of the stirring assembly, and the stirring assembly comprises a feeding pipe; the end part of the feeding pipe is connected with a connecting box, one side, far away from the feeding pipe, of the connecting box is connected with an input pipe, turbine blades are mounted in the connecting box, the upper ends of the turbine blades are connected with a central shaft, the upper end of the central shaft is connected with second stirring blades, and one side, far away from the mixing assembly, of the plate-and-frame filter press is connected with a precision filter. According to the equipment, liquid can be assisted in being mixed with raw material powder by means of flowing of the liquid, the mixing effect of the equipment is improved, residual raw materials can be reduced, the equipment adopts an inclined blowing mode, dried powder and atomized liquid can be separated more conveniently, and drying work can be carried out conveniently.

The invention discloses a hydroxysafflor yellow A modified mitochondria, which is prepared by the following method: mixing and stirring HSYA and mitochondria suspension in PBS (Phosphate Buffer Solution), centrifugally filtering, and then washing to remove uncombined HSYA. The invention also discloses application of the compound in preparation of medicines for treating asthenospermia. The invention provides a powerful, accurate and convertible strategy for resisting male infertility related to environmental toxicants.

The invention relates to the technical field of food, and discloses a composition for relieving visual fatigue and application thereof, the composition for relieving visual fatigue comprises a first functional component and a second functional component; the first functional component is prepared from lutein micro-capsule powder, zeaxanthin micro-capsule powder and hydroxysafflor yellow; the second functional component comprises taurine, vitamin B2, zinc gluconate and sodium hyaluronate. According to the composition, the first functional component and the second functional component are matched for use, synergistic protection is formed from the surface layer to the deep layer of eye tissue, and the dual effects of relieving existing asthenopia symptoms and preventing asthenopia long-term injury can be achieved.