The invention discloses safflower polypeptide aging-reversing cream. The safflower polypeptide aging-reversing cream is prepared from the following raw materials: D-panthenol, a gamma-PGA stock solution, oleophylic titanium dioxide, a coenzyme Q10, silica, ceramide 3, tranexamic acid, malic acid, a water-in-oil emulsifier, cetyl polydimethylsiloxane, safflower seed oil, beewax, a preservative, a glycyrrhiza glabra root extract, carthamin yellow, safflower polypeptide, squalene, potassium azelate diglycinate, hyaluronic acid, propyl paraben, hexapeptides, a blue copper peptide stock solution, chamomile hydrolat and/or rose hydrolat. By scientifically adding the safflower polypeptide, the safflower polypeptide aging-reversing cream has better effects of resisting aging, whitening skin, and fading spots and fine wrinkles, effectively removes dark and yellow skin, conceals flaws, refines pores, improves gloss of the skin, and enables the skin to be elastic, smooth and glossy, and the safflower extract has effects of promoting blood circulation, whitening skin and removing spots, can promote capillary circulation and cell regeneration of the skin, and has functions of reducing wrinklesand delaying aging.