41 results about "Dark urine" patented technology

Belonging to the technical field of Chinese medicine preparation methods, the invention relates to a preparation method of a Chinese medicinal lotion treating dark urine-type cellulitis. Current treatment of dark urine-type cellulitis generally employs antibiotics and sulfonamides, and has the disadvantage of great side effect. A technical scheme adopted by the invention consists of: taking Polyporus, Rhizoma Dioscoreae Hypoglaueae, coix seeds, waxgourd peels, Phaseolus calcaratus, Zanthoxylum bungeanum Maxim, Corn Stigma, gourds, Commelina communis, Polygonum aviculare, Dianthus superbus, akebia stems, Ricepaperplant Pith, Juncus effusus, Patience Dock Roots, Ilex pubescens, Herba Patriniae, Changium smyrnioides, Hemsleya macrosperma, Anemarrhena asphodeloides, radix tinosporae, Trollius chinensis, honeysuckle, Bidens biternata, houttuynia cordata, Herba Lespedezae Cuneatae, hypericum perforatum, Sedum sarmentosum, Sagina subulata, convallaria majalis and licorice, and placing the 31 medicines into water for immersion, then conducting decocting with slow fire, and carrying out filtration to remove the residue, thus obtaining a liquid medicine, i.e. the Chinese medicinal lotion treating dark urine-type cellulitis. The prepared Chinese medicine has the advantages of simple preparation, small toxic and side effect, short treatment course, and high curative rate.

The invention discloses a medicine composition for treating acute pharyngitis. Raw medicines are achyranthes aspera, spurge, Physalis alkekengi, radix scrophularise, myrobalan flesh, and ballonflower. The medicine composition is suitable to treat lung heat and phlegmatic retention diseases of the acute pharyngitis (containing the acute attack of chronic pharyngitis), and symptoms are as follows: swollen sore throat, dryness and searing heat, or itchy throat and dry cough, dysphagia, cough and sputum viscosity, thirst with desire to drink, or fever, dry stool, scanty dark urine, or reddened tongue, thin yellow fur, and slippery and quick pulse. The medicine composition has efficacies of clearing away heat and toxic materials, reducing phlegm and resolving masses, and reducing swelling and relieving sore throat, has less medicine odours and specific drug potency, is safe and effective, and can be prepared into various oral preparations.

The invention relates to a functional health food and in particular relates to a food for changing damp heat constitution and a preparation process thereof. According to reasonable compatibility of medicines, a synergistic effect can be achieved among the effects of the medicines, and the food has the effects of treating symptoms, such as usual dirty and oily complexion, high probability of acne and comedo, red fur and yellow and greasy tongue nature, bitter taste and dry mouth, somatic heaviness and tiredness, annoyance and slacking, eyestring redness, dry or viscous bound stool, scanty dark urine, and high probability of male scrotal moisture and female leukorrhagia, of people with the damp heat constitution.

The invention discloses a Chines medicine composition preparation capable of curing renal calculus. The Chines medicine composition preparation capable of curing the renal calculus is mainly composed of fringed pink, spora lygodii, poria cocos, rhizoma alismatis, grifola, longhairy antenoron herb, plantain seeds, radix cyathulae, myrrh and qizzard pepsin. The Chines medicine composition preparation capable of curing the renal calculus has effects of diuresis inducing and strangurtia treating, has good treatment effects of pain, dark urine, dysuresia caused by the renal calculus and capable of effectively and fast curing the renal calculus. The Chines medicine composition preparation capable of curing the renal calculus is ideal and safe medicine capable of curing the renal calculus.

The invention relates to a Chinese herbal combination for raising blood platelets, and a preparation method of the combination. The Chinese herbal combination is prepared from five traditional Chinese medicines including indigo naturalis, fructus forsythia, hairyvein agrimony, moutan bark and liquorice. The Chinese herbal combination has effects of clearing away heat and toxic materials, cooling blood for hemostasis, dissipating stasis and eliminating ecchymosis, and is mainly applied to primary thrombocytopenic purpura which has the symptoms of petechia or ecchymosis all over the body, having a fever, polydipsia, scanty dark urine, constipation, or epistaxis, gum bleeding, red tongue, yellow coated tongue, and slide number or string number of vessels. The Chinese herbal combination has remarkable test results of clinical pharmacodynamics and high biological availability, and is free from any toxic and side effect.

The invention relates to blood platelet raising capsules, namely a Chinese herbal combination, and a preparation method of the capsules. The Chinese herbal combination is prepared from five traditional Chinese medicines including indigo naturalis, fructus forsythia, hairyvein agrimony, moutan bark and liquorice. The Chinese herbal combination has effects of clearing away heat and toxic materials,cooling blood for hemostasis, dissipating stasis and eliminating ecchymosis, and is mainly applied to primary thrombocytopenic purpura which has the symptoms of petechia or ecchymosis all over the body, having a fever, polydipsia, scanty dark urine, constipation, or epistaxis, gum bleeding, red tongue, yellow coated tongue, and slide number or string number of vessels. The blood platelet raising capsules have remarkable test results of clinical pharmacodynamics and high biological availability, and are free from any toxic and side effect.

The invention relates to a traditional Chinese medicinal composition of lipid-lowering tea and an application of the traditional Chinese medicinal composition. The traditional Chinese medicinal composition is prepared from the following active ingredients: raw hawthorn fruits, roasted cassia seeds, apocynum venetum and liquorice roots. The invention further provides the application of the traditional Chinese medicinal composition. The traditional Chinese medicinal composition has the advantages that through the mixed use of the active ingredients, the efficacies of tonifying spleen, removing dampness and clearing away turbidness, calming liver and suppressing liver-yang, as well as activating and harmonizing Qi and blood are achieved; the traditional Chinese medicinal composition has the functions of promoting blood circulation and resolving dampness, as well as calming the liver and reducing turbidity, and has the main function of treating hyperlipemia, wherein the symptoms of hyperlipemia are paunch, fat body, dizziness and fullness in head, sweating when active, sticky and dirty mouth, ungratifying defecation, dark urine, purplish tongue and thick coating, and thready and slippery pulse, and the patients have the syndrome of damp obstruction and liver-yang hyperactivity.

The invention relates to a Chinese medical lyophilized powder injection used for treating liver cancer, which is essentially prepared by the following raw materials according to weight ratio and by the following processes: 10g of ginseng coarse powder is added with 75 percent of ethanol for refluxing extraction for 2 times; a filter liquor is collected and the ethanol is recycled, thus obtaining a ginseng paste. The ginseng paste is dissolved in distilled water and then subjected to filtration for two times; 1g of secretio bufonis fine powder is added with 85 percent of ethanol for refluxing extraction for 2 times; the ethanol of the filter liquor volatilizes and a secretio bufonis paste is obtained; after 40ml of propylene glycol is used for dissolving the paste, filtration is carried out for two times; liquor obtained from filtration is for a stand-by purpose; the secretio bufonis is combined with the ginseng liquor obtained from filtration, added with 5mg of scopolamine hydrobromide, 80g of manna sugar for dissolution and 0.65micron of membrane for degerming, added with distilled water until the volume thereof is 500ml, subpackaged in tube vials and refrigerated and dried, thus obtaining a finished product. The formula of the product strengthens the body resistance to eliminate pathogenic factors, softens hard lumps to dissipate stagnation, activates blood and dissolves stasis, removes dampness and dispels toxin, clears heat and treats jaundice, and combines approach of tonification and purgation, thus having unique treatment effects on treating liver pain, inappetence, thoracic and abdominal distension, weight loss and weakness, jaundice, coprostasis, dark urine, gray face, yellow tongue coating, wiry and rolling pulse and the like.

The invention discloses a medicine for treating cirrhosis. The medicine is formed by the following traditional Chinese medicines by weight: 5-15g of radix bupleuri, 10-20g of white paeony root, 2-10g of liquorice, 5-15g of orange fruit, 5-15g of dried tangerine peel, 4-16g of nutgrass galingale rhizome and the like. The medicine has the beneficial effects that the components of the medicine supplement each other and have the effects of improving the efficacy and reducing the toxic and side effects; and the medicine is mainly used for treating cirrhosis caused by hepatitis and has obvious curative effects on various cirrhosis symptoms such as reduced appetite, vomit, diarrhea, abdominal distention after eating, mental fatigue, marasmus, tinnitus, lumbago, frequent urination, unease, insomnia, pain in both sides of the chest, liver palms, jaundice, dark urine, meteorism and the like.

The invention relates to a traditional Chinese medicine for treating thrombocytopenic purpura. The traditional Chinese medicine comprises the following components in parts by weight: 150 to 170g of cornus officinalis, 110 to 130g of rumex japonicas, 90 to 110g of pseudo-ginseng, 110 to 130g of astragalus membranaceus, 110 to 130g of angelica sinensis, 110 to 130g of fructus lycii, 90 to 110g of glossy privet fruit, 90 to 110g of herba ecliptae, 90 to 110g of caulis spatholobi, 18 to 22g of american ginseng, and 78 to 82g of callicarpa bodinieri. Other components in parts by weight also can be added to the traditional Chinese medicine based on the components as follows: 6 to 15g of fructus ziziphi jujubae, 6 to 9g of rubia cordifolia and 5 to 9g of cattail pollen. Under the coordination of all the components, the traditional Chinese medicine has the effects of clearing heat and cooling blood, replenishing blood and tonifying Qi, dispersing blood stasis and stopping bleeding and treating the deficiency of both blood and Qi and stagnation of heat stasis leading to thrombocytopenic purpura, such as skin petechiae, ecchymosis, black red, thrombocytopenia, hemorrhage, fever, polydipsia, palpitation, insomnia, vertigo, lack of energy, pain in joints, waist and abdomen, dark urine with burning sensation and constipation. The result of clinical application shows that the traditional Chinese medicine is remarkable in therapeutic effect and low in toxic and side effects and has a good application prospect.

The invention discloses a miraculous pill of ledebouriella and a preparation method of the pill. The miraculous pill of ledebouriella is characterized in that 57g of radix clematidis, 38g of tabasheer, 38g of chinaberry fruits, 50g of mint, 50g of ephedra, 50g of rheum officinale, 50g of mirabilite, 27g of jasmine, 300g of talcum, 100g of balloon flower, 114g of plaster, 57g of chuanxiong rhizome, 50g of angelica, 114g of radix scutellariae, 57g of phillyrin and 228g of liquorice are crushed into crude powder and placed in a circulating ultrasonic extractor, water, germanium powder and tween 60 are added, ultrasonic extraction and jet spray drying are performed to prepare nano extraction powder, and honey is refined and coats the pill to prepare the miraculous pill of ledebouriella. The miraculous pill of ledebouriella is used for treating external cold, internal heat, internal-external sthenia, aversion to cold, strong fever, headache, dry throat, scanty dark urine, constipation, first symptoms of scrofula and rubella eczema, remarkable in curative effect and superior to commercially available miraculous pills of ledebouriella, and achieves fine effects.

The invention discloses a vinegar beverage for treating urinary calculus. The vinegar beverage is prepared from the following main raw materials in parts by weight: 9-15 parts of semen brassicae, 6-12 parts of corn, 10-15 parts of liquorice, 5-10 parts of fructus aurantii, 6-12 parts of the root of three-nerved spicebush, 15-60 parts of lalang grass rhizome, 5-15 parts of ligusticum wallichii, 4.5-9 parts of yellow croaker ear-stone, 5-15 parts of chufa, 2-5 parts of caulis clematidis armandii, 5-15 parts of galium aparine and 60-100 parts of vinegar. The vinegar beverage has the effects of inducing dieresis for treating strangurtia, and clearing damp and promoting dieresis, has a good function of treating pain, dark urine, and dysuresia caused by the urinary calculus, is capable of greatly and relatively rapidly treating the urinary calculus, and is a drug for treating the urinary calculus in a relatively ideal and safe manner.

The invention discloses tea formula with liver protecting and alcoholism relieving functions and a preparation method. The tea formula comprises components in parts by weight as follows: pueraria lobata, poria cocos, largehead atractylodes rhizome, hawthorns, dried orange peel, mung beans, rhizoma alismatis, white hyacinth beans, round cardamom fruit, gardenia jasminoides, liquorice, plantain, vigna umbellate and papaya. The tea formula can clear blood, sooth the liver, harmonize the stomach and regulate the qi, can effectively relieve symptoms such as headache, dizziness, stomachache, nausea, poor spirit and the like caused by drinking. The tea tastes fragrant, sweet and mellow, has effects of helping produce saliva and slake thirst, soothing the liver, expelling toxin, refreshing, restoring consciousness, strengthening the spleen and stomach, moistening the lung, eliminating phlegm, prolonging life, beautifying and the like, can relieve symptoms such as throat phlegm obstructing, constipation, scanty dark urine and the like to a certain extent, can improve the immunity function of a human body to realize the prevention and health care functions when drunk frequently, and can well relieve excessive symptoms of cholesterol, blood pressure, blood lipid and blood glucose.

The present invention relates to a Chinese medicine composition and its preparation process. In particular, it relates to a Chinese medicine prescription for curing the diseases of upper burner dry ness-heat, sore dry throat, toothache, constipation and dark urine, etc, and its preparation process. Said Chinese medicine composition can be made into dripping pills and soft capsule preparation.

The invention provides an external medicine used for treating summer diarrhea, which is made of the following bulk drugs by weight percentages: 10-18% of flavescent sophora root, 10-18% of licorice and 64-80% of talc; the bulk drugs are taken out in proportion and crushed to be 40-500 mesh fine powder, then the powder is evenly mixed and filled in cloth bags. The medicine has the efficacies of clearing away pathogenic heat, eliminating dampness and removing the toxin, can cause the heat and the dampness to be respectively eliminated, thus stopping the diarrhea. The medicine has good effect on bellyache and the diarrhea complicated by pyrexia, thirst and scanty dark urine caused by the summer diarrhea.

The invention discloses a kidney-tonifying and calculus-removing compound preparation for the urinary system. The preparation is prepared from the following main raw materials in parts by weight: 6-12 parts of endothelium corneum gigeriae galli, 2-6 parts of talc, 7-16 parts of dianthus superbus, 9-20 parts of bohadschia, 20-30 parts of wolfberries, 3-9 parts of deer-horn glue, 4-8 parts of clerodendranthus spicatus, 8-17 parts of chingma abutilon seeds, 10-20 parts of semen juglandis and 3-8 parts of fish otolith. The preparation has the functions of inducing diuresis for treating strangurtia and clearing damp and promoting diuresis, has a very good curative effect on ache, dark urine and dysuria caused by urinary calculus, further can tonify kidney and spleen and can effectively and quickly treat urinary calculus, so that the preparation is a relatively ideal and safe medicine for treating urinary calculus and tonifying kidney and spleen.

The invention discloses a Chinese medicinal composition for treating acute pelvic inflammatory disease. The Chinese medicinal composition is composed of the following raw materials by weight: 18-26 parts of lonicera japonica, 12-20 parts of forsythia, 12-20 parts of Sargentodoxa cuneata, 20-28 parts of Patrinia scabiosifolia leaf, 20-30 parts of coix seed, 6-14 parts of Cortex Moutan, 6-14 parts of gardenia jasminoides, 12-20 parts of Radix Paeoniae Rubra, 3-11 parts of almond, 4-12 parts of Rhizoma Corydalis, 4-12 parts of Fructus toosendan, 2-10 parts of frankincense, 2-10 parts of myrrh, 12-20 parts of phellodendron, 10-18 parts of dandelion, 1-5 parts of Pseudo-ginseng, and 4-8 parts of licorice. By means of clearing away heat and toxic materials, removing dampness and expelling pus, the Chinese medicinal composition provided by the invention mainly treats high fever and chillness, or absence of aversion to cold, headache, no sweat or slight sweating, lower abdominal pain aggravated by touch, much leucorrhea, yellow or white color, or red and white coexistence, thick texture and foul smell, dry mouth, nausea and poor appetite, scanty dark urine, dry feces, red tongue, yellow greasy tongue fur, slippery and rapid pulse or bounding pulse.

The invention discloses a medicine for treating diarrhoea. The medicine is composed of the following raw materials in parts by weight: 25-35 parts of Humulus japonicus, 20-30 parts of Breynia fruticosa, 15-25 parts of elsholtzia, 10-20 parts of kudzu root, 10-20 parts of skunk bugbane, 6-15 parts of Bighead Atractylodes Rhizome, 3-9 parts of dangshen, 3-6 parts of dried orange peel and 1-5 parts of licorice root. The invention also discloses a preparation method of the medicine capsule. The medicine has the advantages of strict composition, fewer drugs and intense effect, has favorable curative effects on diarrhoea caused by moist heat and weakness of the spleen and stomach, and can obviously improve urgent diarrhea or uncomfortable excretion, brown excrement, hot anus, dysphoria with smothery sensation, thirst, abdominal pain, scanty dark urine, yellow tongue fur and other symptoms of the patient with diarrhea.

The invention discloses a medicine capable of quickly alleviating drunkenness. The medicine is prepared in a way that rhizoma zingiberis recens, Punica granatum L. juice, mori fructus, fructus canarii, radix puerariae lobatae, Pinus massoniana Lamb. powder, rhizoma phragmitis, rhizoma imperatae, glycyrrhizae radix, rhizoma dioscoreae and radix panacis quinquefolii are taken as raw materials and are decocted and extracted according to a certain mass ratio. The medicine disclosed by the invention can be prepared into any one common oral administration dosage form, has the functions of promotingthe secretion of saliva or body fluid, preventing vomiting, clearing away heat and toxic materials, invigorating spleen to remove dampness, dispelling the effects of alcohol, relieving restlessness and the like, has an obvious curative effect for nausea, vomiting, absent mind, dizziness, sleepiness, teetering, scanty dark urine and the like caused by insobriety, has a treatment function for alcoholic liver injuries, hypoimmunity, usual dry mouth and dry throat, liver fire hyperactivity and the like, is quick to take effects, and does not have toxic or side effects.

The present invention relates to the technical field of traditional Chinese medicine. The purpose of the present invention is to provide a Chinese medicine decoction for improving yellow urine according to the understanding mechanism of traditional Chinese medicine for improving yellow urine. ‑20 parts, 6‑10 parts of forsythia, 15‑25 parts of Gorgon fruit, 15‑25 parts of Codonopsis pilosula, one dose per day, 5 days as a course of treatment, the raw materials of the traditional Chinese medicine decoction provided by the invention are easy to get, good in curative effect, and have no side effects , After more than hundreds of cases of improving urine yellow patients, the effective rate is more than 92% after statistics.

The invention discloses a medicine for the treatment of chronic diarrhea, which includes following raw materials that are according to parts of weight: parts of 10-30 fruticose breyniae, parts of 10-25 scandent hop, parts of 10- 30 the root of kudzuvine, parts of 5- 20 leaf and twig rattletop, parts of 6-15 bighead atractylodes, parts of 3-9 rhizome codonopsis , parts of 3-6 pilosula pericarpium citri, parts of 1-5 reticulatae liquorice. Medicine for the treatment of chronic diarrhea discloses the preparation method of the drug capsule. Medicine for the treatment of chronic diarrhea has the advantage of being rigorous in component. Although the medicine is not composed by many kinds of materials, the medicine is very effective. The medicine is beneficial to the diarrhea due to damp-heat, chronic diarrhea caused by spleen-stomach deficiency. The medicine can effectively relieve symptoms patient of urgent diarrhea or uncomfortable diarrhea, tawny defecation, burning pain in anus, dysphoria with smothery sensation, thirst, bellyache, scanty dark urine and yellowish fur.

The invention discloses a low-current graphene heating patch. The patch includes a heating cloth sleeve, a heating wire, a wire, an automatic switch and an interface. The heating cloth sleeve is internally provided with the heating wire, one end in the heating cloth sleeve is provided with the wire, the wire and the heating wire are in serial connection, an automatic switch is embedded in one endof the front surface of the wire, the wire and the automatic switch are in serial connection, the input end of the wire is connected with the interface, and the interface and the wire are in serial connection. The heating cloth sleeve is made by uniformly mixing 50% of graphene and 50% of high temperature silica gel, the permeation effect is increased, the heating wire is in an S shape, the heat generation speed of the heating patch can be increased, the heating patch can take effect rapidly, and the formula A can be mainly used for treating excess heat syndromes such as fever, sweating, greatvexation, thirst, ravings, delirium, scanty dark urine, yellow and dry furred tongue, large pulse and the like and treating various excess heat syndromes caused by lung heat, stomach fire and heart fire.

The invention relates to a Chinese herbal combination for raising blood platelets, and a preparation method of the combination. The Chinese herbal combination is prepared from five traditional Chinese medicines including indigo naturalis, fructus forsythia, hairyvein agrimony, moutan bark and liquorice. The Chinese herbal combination has effects of clearing away heat and toxic materials, cooling blood for hemostasis, dissipating stasis and eliminating ecchymosis, and is mainly applied to primary thrombocytopenic purpura which has the symptoms of petechia or ecchymosis all over the body, having a fever, polydipsia, scanty dark urine, constipation, or epistaxis, gum bleeding, red tongue, yellow coated tongue, and slide number or string number of vessels. The Chinese herbal combination has remarkable test results of clinical pharmacodynamics and high biological availability, and is free from any toxic and side effect.

The invention discloses a heart calming medicine. The medicine is prepared from tortoises with internal organs removed, spina date seeds, poria cocos, Chinese yams and longan. The medicine has the effects of nourishing yin to lessen fire and nourishing blood for tranquilization, and is used for treating symptoms such as palpitation, shortness of breath, insomnia, amnesia, scanty dark urine and the like; and the invention provides a preparation method of the heart-calming medicine, the extraction rate of the medicinal materials is increased, the absorption effect of the medicinal materials is good, and the economic benefit is high; and in order to realize industrial production, the invention provides a tortoise treatment device for preparing the heart-calming medicine, according to the device, after the tortoise is cut open through a cutting saw blade, and the tortoise is broken open along the cutting opening through a mechanical arm clamp, so that internal organs are exposed, then the surface of the tortoise is cleaned and the internal organs are treated through a water spraying gun, the purpose of cleaning the tortoise is achieved, the cleaning efficiency is high and the effect is good.

The invention discloses a medicine composition with functions of clearing heat, removing toxicity, raising yang and relieving diarrhea. The medicine composition comprises, by weight, 20-30 parts of radix puerariae, 20-30 parts of rhizoma cimicifugae, 10-20 parts of breynia fruticosa, 10-20 parts of humulus japonicus, 10-15 parts of flos lonicerae, 10-15 parts of fructus forsythiae, 6-15 parts of rhizoma atractylodis macrocephalae, 3-9 parts of radix codonopsis, 3-6 parts of pericarpium citri reticulatae and 1-5 parts of radix glycyrrhizae. The invention further discloses a preparation method of capsules prepared by the medicine composition. The medicine composition is precise in formula, contains few medicines but is specific in efficacy, is excellent in curative effect on diarrhea caused by damp-heat and chronic diarrhea caused by spleen and stomach deficiency, and is capable of evidently improving symptoms such as urgent diarrhea or ungratifying diarrhea, yellow brown excrement, burning pain in anuses, restless fever, thirst, abdominal pain, scanty dark urine and yellowish fur of patients suffering from the chronic diarrhea.

The invention discloses a medicine for treating damp-heat diarrhea. The medicine comprises the following traditional Chinese medicines in parts by weight: 10-30 parts of breynia fruticosa, 10-25 parts of humulus scandens, 10-30 parts of radix puerariae, 5-20 parts of rhizoma cimicifugae, 10-15 parts of semen coicis, 10-15 parts of cortex magnoliae officinalis, 6-15 parts of rhizoma atractylodis macrocephalae, 3-9 parts of radix codonopsis, 3-6 parts of pericarpium citri reticulatae and 1-5 parts of licorice. The invention further discloses a preparation method of medicine capsules. The medicine adopts a rigorous prescription, is concentrated in efficacy due to a few medicines adopted, has good curative effect on damp-heat diarrhea and can significantly relieve chronic diarrhea caused by damp, heat and weakness of the spleen and the stomach, in particular to symptoms such as diarrhea urgency, non-smooth diarrhea, yellow brown stool, scorch of anus, fever with restlessness, thirst, abdominal pain, scanty dark urine, slimy yellow tongue fur and the like of chronic diarrhea patients with symptoms of damp-heat diarrhea particularly.

The invention relates to a traditional Chinese medicine composition for treating urinary calculus. The traditional Chinese medicine composition is mainly prepared from herba pyrrosiae, chicken gizzard membrane, poria cocos, rhizome alismatis, polyporus umbellatus, corydalis tuber, plantain seed, euphorbia helioscopia and myrrh. The traditional Chinese medicine composition has the effects of promoting urination and treating stranguria and promoting urine and excreting dampness, has a very good treatment effect on pain, dark urine and dysuria, which are caused by urinary calculus, can be used for treating urinary calculus in an extremely effective and relatively fast manner, and is a relatively ideal and safe drug for treating urinary calculus.