The invention relates to a Chinese medical lyophilized powder injection used for treating liver cancer, which is essentially prepared by the following raw materials according to weight ratio and by the following processes: 10g of ginseng coarse powder is added with 75 percent of ethanol for refluxing extraction for 2 times; a filter liquor is collected and the ethanol is recycled, thus obtaining a ginseng paste. The ginseng paste is dissolved in distilled water and then subjected to filtration for two times; 1g of secretio bufonis fine powder is added with 85 percent of ethanol for refluxing extraction for 2 times; the ethanol of the filter liquor volatilizes and a secretio bufonis paste is obtained; after 40ml of propylene glycol is used for dissolving the paste, filtration is carried out for two times; liquor obtained from filtration is for a stand-by purpose; the secretio bufonis is combined with the ginseng liquor obtained from filtration, added with 5mg of scopolamine hydrobromide, 80g of manna sugar for dissolution and 0.65micron of membrane for degerming, added with distilled water until the volume thereof is 500ml, subpackaged in tube vials and refrigerated and dried, thus obtaining a finished product. The formula of the product strengthens the body resistance to eliminate pathogenic factors, softens hard lumps to dissipate stagnation, activates blood and dissolves stasis, removes dampness and dispels toxin, clears heat and treats jaundice, and combines approach of tonification and purgation, thus having unique treatment effects on treating liver pain, inappetence, thoracic and abdominal distension, weight loss and weakness, jaundice, coprostasis, dark urine, gray face, yellow tongue coating, wiry and rolling pulse and the like.