The invention discloses a medicine composition for treating primary hypertension and a preparation method thereof. The medicine composition is mainly prepared from vitis flexuosa thumb., pternopetalum nudicaule(de Boiss.) hand.-mazz, botrychium japonicum, a rubus pluribracteatus root, thysanolaena maxima, brassica integrifolia, a paper mulberry root, an artocarpus hypargyreus root, oberonia iridifolia Lindl, piptanthus concolor craib, henon bamboo juvenile leaves, phyllanthus emblica, evening primrose extract, lemon extract and moyeam tea extract. Based on the traditional Chinese medicine theory, the Medicine composition is applied according to symptoms, the formula is precise, reasonable compatibility is achieved, and the Medicine composition has the functions of removing heat to cool blood, encouraging production of body fluid to extinguish thirst, removing toxicity for detumescence, removing liver-fire for improving eyesight, stopping bleeding and reducing blood pressure, can further effectively remove toxicity and relieve mental stress, promotes a normal organism diet, clears away smoke and dispels the effects of alcohol, and is remarkable in treatment effect, mild in medicinal effect and free of side effects. The preparation technology of the Medicine composition for treating primary hypertension is simple, the production cost is low, and good medical value is achieved.