51 results about "Occlusive disease" patented technology

The invention relates to a stent-graft with a bioabsorbable structure and a permanent graft for luminal support and ‘treatment of arterial fistulas, occlusive disease, and aneurysms. The bioabsorbable structure is formed from braided filaments of materials such as PLA, PLLA, PDLA, and PGA and the graft is formed from materials such as PET, ePTFE, PCU or PU.

A microcatheter system that allows for vascular infusion into retinal veins for extended periods of time. The microcatheter system includes a flexible cannula that is inserted into the retinal vein lumen and that remains stably within the retinal vein lumen without being held by a robot, micromanipulator or similar holding devices. The microcatheter system is particularly suitable for the treatment of retinal venous occlusive disease.

A prosthesis is provided for treating aneurysms, occlusive disease of vessels and body organs, and arterio-venous fistulas, occurring in single and bifurcated lumens. The prosthesis comprises an expandable coiled sheet portion having a biocompatible graft, either a sheet or tube, affixed thereto along part or all of the circumference of the coiled sheet portion. The prosthesis has a small delivery profile, making it suitable for use in a variety of body vessels. Methods of making and deploying the prosthesis in single and bifurcated lumens are also provided.

The present invention is a technique and apparatus for acquiring anatomic information used in diagnosing and characterizing abdominal aortic aneurismal disease and the like. This technique provides anatomic information, in the form of images, using a combination of a plurality of magnetic resonance angiography sequences, including a spin-echo and four contrast enhanced (e.g., gadolinium) magnetic resonance angiography sequences. The anatomic images may be used in, for example, pre-operative, operative and post-operative evaluation of aortic pathology, including aneurysms, atherosclerosis, and occlusive disease of branch vessels such as the renal arteries. The gadolinium-enhanced magnetic resonance angiography provides sufficient anatomic detail to detect aneurysms and all relevant major branch vessel abnormalities seen at angiography operation. This technique and apparatus allows for imaging the aorta at a fraction of the cost of conventional aortography and without the risks of arterial catheterization or iodinated contrast.

The kits and methods of the present invention relate to the diagnosis of cardiovascular disorders. In one aspect, the invention discloses a method and a kit for determining whether a subject has a fragile plaque disorder. In one aspect, the invention discloses a method and a kit for determining whether the subject has an occlusive disorder. In one aspect, the invention discloses a method and a kit for determining whether the subject has a restenosis disorder. Other methods of the present invention relate to the selection of therapeutics for a patient with a cardiovascular disease.

The invention relates to the technical field of medical appliances, in particular to a support type artificial venous blood vessel with valve for treating venous reflux diseases and venous return obstruction diseases. The artificial venous blood vessel comprises artificial valve (1) inside the artificial blood vessel, a metal support (2) attached to the outer wall of the artificial blood vessel to support the artificial blood vessel, a metal ring (3) attached to the metal support to support the valve and an artificial blood vessel (4) beyond the range of the support. The artificial venous blood vessel is produced according to the normal vessel valve structure of the human body, the vessel valve can be opened and closed freely, the supporting strength of the support is proper, and the supporting metal ring can maintain the normal state of the vessel valve. The artificial venous blood vessel has the advantages of reasonable structure, low fabrication cost and good histocompatibility, and can be used for valve repair operation for lower limb deep vein, valve repair operation for upper limb deep vein and main vein return obstruction disease of four limbs (especially occlusive diseases) After the vein of the pathologic section is resected, the support type artificial venous blood vessel with the valve is stitched on the normal vein, the operation is simple, and the operative wound is small.

A blood circulation and channel invigorating soup is an obviously effective medicine for curing thromboangitis obliterans, arteriosclerosis occlusive diseases, arteritis, phlebeurysma, vein valve insufficiency, deep venous thrombus, shallow venous thrombus, peripheral neuritis, Raynaud's disease, diabetic gangrene, carotid sclerosis plaque formation, cerebral arteriosclerosis thrombosis, cerebral circulation insufficiency, and various artery and vein blood stasis syndromes. The soup is composed of ginseng, hairy deerhorn, pangolin, leech, earthworm, scorpio, female ground beetle, red sage root, resina draconis, pseudo-ginseng, angelica, cortex moutan, safflower, forsythia, centipede and licorice. The soup has the functions of promoting blood circulation by removing blood stasis, reducing swelling and stopping pain, reducing blood viscosity, dissolving thrombus, dredging blood vessel, and repairing vein valve, and the functions of improving blood circulation, promoting healing abscess and the like, and is used for curing thromboangitis obliterans, arteriosclerosis occlusive diseases, arteritis, phlebeurysma, vein valve insufficiency, deep venous thrombus, shallow venous thrombus, peripheral neuritis, Raynaud's disease, diabetic gangrene, carotid sclerosis plaque formation, cerebral arteriosclerosis thrombosis, cerebral circulation insufficiency, and various artery and vein blood stasis syndromes, can achieve the effect of curing both symptoms and root causes, can achieve the aim of no relapse after recovery; approved by clinic tests, the soup can effectively release the pain of a plurality of patients and receive positive comments from the patients.

Technique and apparatus for acquiring anatomic information used in diagnosing and characterizing abdominal aortic aneurismal disease and the like. This technique provides anatomic information, in the form of images, using a combination of a plurality of magnetic resonance angiography sequences, including a spin-echo and four contrast enhanced (e.g., gadolinium) magnetic resonance angiography sequences. The anatomic images may be used in, for example, pre-operative, operative and post-operative evaluation of aortic pathology, including aneurysms, atherosclerosis, and occlusive disease of branch vessels such as the renal arteries. The gadolinium-enhanced magnetic resonance angiography provides sufficient anatomic detail to detect aneurysms and all relevant major branch vessel abnormalities seen at angiography operation. This technique and apparatus allows for imaging the aorta at a fraction of the cost of conventional aortography and without the risks of arterial catheterization or iodinated contrast.

The present invention relates to methods and compositions comprising compounds for the treatment of pathophysiological diseases resulting from inflammatory responses. In particular, the present invention relates to compounds that inhibit or block the production of glycated proteins that induce inflammatory responses associated with signaling in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention relates to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as perlecan. The invention further relates to the use of the compounds in the treatment of vaso-occlusive diseases such as restenosis and atherosclerosis which are characterized by smooth muscle proliferation.

An orally applied medicine of common pueraria flavone for treating coronary heart disease, angina pectoris, the occlusive diseases of vein, artery and retina, etc is prepared from the common pueraria flavone and additive through proportional mixing. Its advantages are high curative effect and low dosage.

Novel human protein C derivatives are described. These derivatives have increased anti-coagulation activity compared to wild-type protein C and retain the biological activity of the wild-type human protein C. These derivatives will require either less frequent administration and/or smaller dosage than wild-type human protein C in the treatment of acute coronary syndromes, vascular occlusive disorders, hypercoagulable states, thrombotic disorders and disease states predisposing to thrombosis.

The invention relates to application of platycodin D in preparation of medicines for preventing and treating pulmonary hypertension. According to the technical scheme, platycodin D and compositions containing platycodin D are used for treating pulmonary hypertension and cardiovascular related diseases caused by pulmonary hypertension. Experimental researches discover that platycodin D can be used for preventing and treating arbitrary one or more of idiopathic pulmonary hypertension, heritable pulmonary arterial hypertension, drug and toxin related pulmonary hypertension, hazard factor or disease related pulmonary hypertension, pulmonary hypertension caused by pulmonary veno-occlusive disease and (or) pulmonary capillary hemangiomatosis-like diseases, and persistent pulmonary hypertension of newborn.

The invention relates to a preparation method of saponin of radix adenophorae as well as an application of the saponin of radix adenophorae, which is prepared in accordance with technical scheme of the invention, in treating medicines for treating pulmonary arterial hypertension and related cardiovascular diseases caused by the pulmonary arterial hypertension. Based upon experimental studies, the saponin of radix adenophorae provided by the invention can take an obvious effect on reducing mean pulmonary arterial pressure (MPAP), right ventricle systolic pressure (RVSP) and right ventricular hypertrophy index (RVHI) of the pulmonary arterial hypertension. The saponin of radix adenophorae can be used for preventing and treating one or more diseases of special pulmonary arterial hypertension, heritable pulmonary arterial hypertension, drug and poison related pulmonary arterial hypertension, risk factor or disease related pulmonary arterial hypertension, pulmonary arterial hypertension caused by pulmonary veno-occlusive disease and (or) pulmonarycapillary hemangiomatosis, and neonatal persistent pulmonary arterial hypertension.