83 results about "Morus Alba Root" patented technology

The present invention relates to the field of biomedicine technology, and more particularly to a whitening and freckle-removing active composition, a preparation method, and application thereof in cosmetics. The whitening and freckle-removing active composition comprises a Rhodiola rosea (RHODIOLA CRENULATA) root extract, a MORUS ALBA (MORUS ALBA) extract, and hexapeptide-2. The whitening and freckle-removing active composition has multi-target effects, and the components are reasonably matched, thereby achieving significant synergistic effects in terms of antioxidant effects and whitening and freckle-removing effects.

The invention provides a medicine composition for treating colorectal cancer and application thereof, and relates to the field of traditional Chinese medicine. The medicine composition for treating colorectal cancer comprises the following raw materials in parts by weight: 5-10 parts of astragalus membranaceus, 10-15 parts of turtle shell, 5-20 parts of leech, 3-5 parts of pericarpium citri reticulatae, 5-10 parts of caulis perllae, 5-8 parts of pseudo-ginseng, 5-10 parts of ginseng, 8-16 parts of agilawood, 10-20 parts of mulberry, 10-20 parts of liquorice and 10-20 parts of centella asiatica. Astragalus mongholicus and turtle shell are used as monarch drugs, centella asiatica is used as a conductant drug, leech, pericarpium citri reticulatae, caulis perllae and pseudo-ginseng are used as ministerial drugs, so that the traditional Chinese medicine composition not only has the effect of assisting the monarch drugs in removing stasis and eliminating diseases, but also has the effects of removing food retention and relieving pain, regulating qi-flowing for evil breezing, clearing heat and promoting diuresis, and detoxifying and diminishing swelling, and ginseng, agilawood, mulberry and liquorice are used as adjuvant drugs to achieve the effects of tonifying spleen and kidney and absorbing qi. The traditional Chinese medicine composition can make up visceral organ asthenia caused by breaking blood, promoting circulation of qi, removing blood stasis and eliminating diseases in the monarch medicine, the ministerial medicine and the conductant medicine.

The invention relates to a traditional Chinese medicine composition for treating spleen and kidney deficiency type alopecia, the medicine composition comprises active ingredients and medically acceptable auxiliary materials, and the active ingredients are prepared from the following raw material medicines in percentage by weight: 8-10% of radix rehmanniae preparata, 6-8% of semen cuscutae, 6-8% of glossy privet fruit, 16-20% of radix astragali, 8-10% of fructus lycii, 8-10% of herba taxilli, 6-8% of roasted rhizoma atractylodis macrocephalae and 8-10% of radix salviae miltiorrhizae. , 8-10% of mulberry, 5-7% of dahurian angelica root, and 8-10 The pharmaceutical composition disclosed by the invention has a remarkable effect of treating spleen and kidney deficiency type alopecia.

The application discloses an active polypeptide and application thereof in treating diabetic peripheral neuropathy, and belongs to the technical field of biological polypeptide drugs. An amino acid sequence of the active polypeptide is QVWPDGFVGLAKLWI, which is obtained by step-by-step enzymatic extraction and purification from Morus alba L. which is a homology of medicine and food. The polypeptide can significantly inhibit oxidative stress, inflammatory infiltration and cell apoptosis of Schwann cells induced by a high-sugar environment, and repair the function of damaged nerve cells. Meanwhile, the polypeptide can effectively improve abnormal sciatic nerve conduction function of a diabetic model mouse. The active polypeptide can be used for preparing a drug for treating diabetic peripheral neuropathy, and provides a new candidate drug and research and development direction for the targeted treatment of diabetic peripheral neuropathy.

The invention discloses a traditional Chinese medicine composition for promoting hair growth and a preparation method thereof. The traditional Chinese medicine composition comprises an oral composition and an external lotion. The oral prescription comprises 11 traditional Chinese medicines in parts by weight: radix angelicae, poria cocos, amomum kravanh, polygonum multiflorum, safflower carthamus, angelica sinensis and the like, the polygonum multiflorum and mulberry are monarch drugs for nourishing liver and kidney, the angelica sinensis and the like are ministerial drugs for promoting blood circulation to remove blood stasis, the radix angelicae and the like are adjuvant drugs for dispelling wind and arresting itching, and the liquorice is a conductant drug for harmonizing the medicines; the external lotion is composed of Ligusticum wallichii, Gleditsia sinensis and speranskia tuberculata, the Ligusticum wallichii expands blood vessels and increases nutrition delivery, the Gleditsia sinensis cleans scalp and inhibits fat overflow and alopecia, and the orchid grass inhibits bacteria and diminishes inflammation. The composition comprehensively conditions the body and scalp environment through combination of oral administration and external use. Clinical tests show that after the traditional Chinese medicine composition is used for 3 months, the alopecia of more than 80% of subjects is reduced, the growth speed of new hair is averagely increased by 30%, the hair quality is improved, the safety is high, the adverse reaction is few, the effect is obviously superior to that of similar products, and a new effective choice is provided for promoting hair growth.

The invention belongs to the technical field of acupoint patches, and particularly relates to an acupoint patch acting on joints and a preparation method thereof.The acupoint patch comprises a breathable non-woven fabric, the front portion of the breathable non-woven fabric is coated with a medical adhesive layer and provided with a plurality of tearing cracks, the middle of the front side of the breathable non-woven fabric is connected with a cotton backing ring in an adhesive mode through the medical adhesive layer, and a medicine cake is arranged in the cotton backing ring; the medicine cake is prepared from the following components in parts by weight: 12 parts of notopterygium root, 12 parts of radix angelicae pubescentis, 12 parts of ramulus mori, 12 parts of pawpaw, 12 parts of rhizoma sparganii, 10 parts of ligusticum wallichii, 6 parts of cassia twig, 15 parts of angelica sinensis, 15 parts of kadsura pepper stem, 15 parts of salvia miltiorrhiza, 5 parts of frankincense, 5 parts of myrrh, 10 parts of cornu cervi pantotrichum and a proper amount of collagen peptide. By adding the cornu cervi pantotrichum and the collagen peptide, both the cornu cervi pantotrichum and the collagen peptide can effectively relieve arthralgia and improve joint flexibility, and meanwhile, the collagen peptide can maintain skin elasticity, promote wound healing and prevent skin damage to the position where a user uses the acupoint patch for a long time.

The invention belongs to the field of food nutrition and pharmacy, and particularly relates to folium mori crude polysaccharide and application thereof. An extract rich in mulberry leaf polysaccharide is extracted from mulberry leaves through a specific extraction process, and it is found through an in-vitro antibacterial experiment that the crude mulberry leaf polysaccharide has the direct inhibiting and killing effect on helicobacter pylori (Helicobacter pylori). In-vitro intestinal flora fermentation research shows that the folium mori crude polysaccharide can effectively correct intestinal flora disorder caused by triple antibiotics for treating helicobacter pylori, meanwhile, the short-chain fatty acid level is remarkably improved, and the helicobacter pylori abundance in intestinal flora is reduced. The application field of mulberry leaf polysaccharide is widened, and important reference is provided for developing products for adjuvant therapy of H.pylori infection and intestinal microecology regulation based on natural polysaccharide.

The invention provides application of loranthus parasiticus in preparation of a lipid-lowering medicine. The application has the advantages that the loranthus parasiticus extract can effectively improve HFD-induced obesity and glucose and lipid metabolism disorder; the loranthus parasiticus extract can relieve adipose tissue enlargement and liver fatty degeneration.

A composition for enhancing ATPase activity and supplementing ATP, and a preparation method therefor and the use thereof. The composition comprises the following raw materials: Poria cocos, Rosae rugosae flos, Lycii fructus, Citri reticulatae pericarpium, Morus alba fructus, Jujubae fructus, Polygonati odorati rhizoma, Dimocarpus longan, Polygonati rhizoma and Asini corii colla. The method for preparing the composition product comprises the following steps: (1) selecting one or several raw materials in a formulation, separately soaking the raw materials in a solvent of 5-30 times the amount of the raw materials for 10 min to 5 h, and then performing heating extraction 1-4 times, each time for 10 min to 5 h, so as to obtain extracts; (2) combining the extracts, and concentrating same into a thick paste; and (3) dissolving Asini corii colla by adding an appropriate amount of water, and uniformly mixing same with the thick paste. The product is used for improving glucose uptake, enhancing ATPase activity and increasing cellular ATP content.

The present application belongs to the technical field of biological medicine, and particularly relates to a pharmaceutical composition for treating pulmonary fibrosis and a preparation method thereof. The composition comprises the following raw materials in parts by weight: 12-18 parts of Astragalus membranaceus, 6-12 parts of Ophiopogon japonicus, 4-10 parts of Poria cocos, 1-3 parts of Radix Glycyrrhizae, 10-16 parts of Salvia miltiorrhiza, 6-12 parts of Scutellaria baicalensis, 4-10 parts of Morus alba, 2-6 parts of Pericarpium Citri Reticulatae Viride, 1-4 parts of Sophora flavescens and 1-4 parts of Fritillaria cirrhosa. The present application is a three-phase and fixed-ratio compound of polysaccharides, phenolic acids and flavonoids. The polysaccharides are obtained by water extraction and alcohol precipitation, and are used as a mucosal retention adhesion carrier. The phenolic acids and flavonoids are extracted by low-degree ethanol refluxing, so as to ensure the structural integrity and maintain stability. The alkaloids are extracted by ethanol and then mildly salified, so as to reduce irritation and adsorption loss. The polysaccharides are then subjected to selective light fermentation to build a slightly acidic environment. In the compounding process, a buffer system is used to adjust pH, and cyclodextrin is used to stably bind the components. The three phases synergistically intervene in oxidation-inflammation-fibrosis.

This invention relates to the field of health products or food technology, and more specifically to a composition and its application in removing dampness and controlling blood sugar, balancing blood pressure, and regulating blood lipids. The invention provides a composition for removing dampness and controlling blood sugar, balancing blood pressure, and regulating blood lipids, comprising Poria cocos extract, Astragalus membranaceus extract, hirudin, and at least one or more of Eucommia ulmoides extract, Gynostemma pentaphyllum extract, and Morus alba twig extract. The composition provided by this invention utilizes extracts from at least four precious Chinese medicinal herbs to exert a synergistic effect, jointly achieving the effects of lowering blood pressure, removing dampness and lowering blood sugar, and lowering blood lipids.

The invention relates to the technical field of instant food production, and discloses a making process of a convenient mushroom hotpot, which comprises the following steps of: firstly, selecting basic mushrooms of which the first type is shiitake mushroom, coriaria sinica, pleurotus citrinopileatus, black fungus, pleurotus cornucopiae, velvet antler mushroom, cordyceps flower and hericium erinaceus, and the second type is tremella aurantialba and bamboo fungus; cleaning and removing impurities, adding water into the first type of mushrooms, heating at 100-120 DEG C for 30 minutes, adding the second type of mushrooms, and continuously heating for 20 minutes to obtain a mixed system containing cooked mushrooms and mushroom stock; and after solid-liquid separation, adding seasonings into the mushroom stock soup, heating to prepare a mushroom soup bag, sealing the cooked mushrooms to form a mushroom bag, and packaging the mushroom soup bag and the mushroom bag together to obtain the product. According to the scheme, the problems that basic mushroom combination of an existing convenient mushroom hotpot is not clear, the taste and the umami are insufficient due to the fact that heating is not conducted according to characteristics differentially, and the flavor is poor due to the fact that mushroom soup is not original soup are solved, and the product is convenient to eat and stable in quality.

The invention discloses a traditional Chinese medicine composition for treating obesity phlegm-dampness obstructing spleen syndrome. Comprising the following raw material medicines in parts by weight: 18-25 parts of astragalus membranaceus, 11-15 parts of bighead atractylodes rhizome (fried), 11-15 parts of poria cocos, 8-12 parts of rhizoma alismatis, 3-5 parts of coptis chinensis (fried with wine), 4-6 parts of rheum officinale (fried with wine), 8-12 parts of semen cassiae (fried), 7-12 parts of radix bupleuri (fried with vinegar), 11-15 parts of hyperforin perforatum, 13-18 parts of oriental wormwood, 10-15 parts of salvia miltiorrhiza (fried with wine), 7-9 parts of curcuma zedoary (fried with vinegar), 7-10 parts of polygonum cuspidatum, 14-20 parts of herba epimedii (fried), 6-8 parts of rhizoma zingiberis and 10-15 parts of glossy privet fruit (steamed with wine). The traditional Chinese medicine composition is prepared from 14-20 parts of prepared rehmannia roots, 18-25 parts of hawthorn fruits, 10-15 parts of lotus leaves, 8-12 parts of mulberry twigs, 7-9 parts of baikal skullcap roots (roasted with wine), 8-12 parts of polygala roots, 10-15 parts of kudzuvine roots and 7-9 parts of licorice roots (roasted). The traditional Chinese medicine composition is researched and developed on the basis of complex pathogenesis and pathogenesis of the obesity phlegm-dampness obstructing spleen syndrome, and has an expected effect of treating the obesity phlegm-dampness obstructing spleen syndrome.

The invention provides a traditional Chinese medicine composition for treating alopecia areata and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine composition is prepared from the following components in parts by mass: 10 to 30 parts of radix rehmanniae recen, 10 to 30 parts of radix rehmanniae preparata, 10 to 30 parts of caulis spatholobi, 10 to 30 parts of caulis polygoni multiflori, 30 to 50 parts of radix astragali, 10 to 20 parts of rhizoma chuanxiong, 10 to 30 parts of radix paeoniae alba, 5 to 20 parts of rhizoma gastrodiae, 5 to 20 parts of cordyceps sinensis, 10 to 30 parts of herba ecliptae, 10 to 30 parts of mulberry and 5 to 20 parts of fructus chaenomelis. The effect is stronger, and no side effect exists. The tincture prepared by the invention is a pure external preparation without systemic toxicity, has no side effects such as hirsutism and skin atrophy after long-term use, and is especially suitable for sensitive scalp patients.

The present invention relates generally to methods and compositions useful for treating skin, and in particular to improve the appearance of droopy, loose, sagging, and / or flaccid skin and / or to improve facial contouring. In some aspects, disclosed are methods comprising topically applying to the skin an effective amount of a topical composition comprising escin, Ascophyllum nodosum extract, caffeine, Coleus barbatus extract, Hedychium coronarium root extract, Argania spinosa oil, Rosmarinus officianalis leaf extract, and / or Morus alba fruit extract.

The invention belongs to the technical field of cosmetics, and particularly relates to a composition with effects of improving skin color and resisting oxidation as well as a preparation method and application of the composition. The composition with the effects of improving the skin color and resisting oxidation, provided by the invention, is prepared by compounding an ormosia henryi bark extract, a mulberry root bark extract, a raspberry fruit extract, 4-butylresorcinol and ascorbyl tetraisopalmitate; wherein in the preparation method of the ormosia henryi bark extract, the ormosia henryi bark is extracted by adopting a mode of combining eutectic emulsion standing extraction with micro-jet secondary extraction, the stability of active substances in the obtained ormosia henryi bark extract is good, and the extraction efficiency is high; the extraction method is low in production cost and easy to operate, and conforms to the green chemistry principle. The composition provided by the invention has excellent effects of improving skin color and resisting oxidation and is mild and non-irritant, the preparation method is simple and easy to operate, and industrial actual large-scale production and application are facilitated.

The invention relates to a traditional Chinese medicine composition for treating rhinitis, a preparation and a preparation method, and relates to the field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following components in parts by weight: 5-20 parts of fructus xanthii; 5-20 parts by weight of citronella; 3-15 parts by weight of cacumen biotae; 3-15 parts by weight of sweet almond; 4-18 parts by weight of mulberry leaves; 5-20 parts by weight of Tianshan ice chrysanthemum; 5-20 parts by weight of wild chrysanthemum flower; 5-20 parts by weight of folium apocyni veneti; 4-18 parts by weight of fritillaria pallidiflora; and 2-10 parts by weight of sea buckthorn fruit oil. According to the traditional Chinese medicine composition, through reasonable compatibility of the components, the effects of relieving stuffy nose, resisting inflammation, moistening dryness, regulating body fluid and the like can be achieved, and the traditional Chinese medicine composition has good treatment and improvement effects on acute rhinitis, allergic rhinitis and chronic hypertrophic rhinitis.

The invention discloses a traditional Chinese medicine medicated bath medicine bag for treating wind-cold-dampness arthralgia, and belongs to the technical field of traditional Chinese medicines. The medicine bag is prepared from 10-20 parts by mass of broussonetia papyrifera roots, pine roots, albizia roots, Chinese redbud roots, maidenhair roots, mulberry roots, banyan roots, camphor tree roots, paulownia roots and willow roots, preferably 15 parts. The preparation method comprises the steps of raw material weighing, drying treatment, mixing and subpackaging into an air-permeable fiber medicine bag, the medicine bag is a 20 cm * 15 cm rectangular cloth bag, three sides are sealed, and one side is provided with an opening and closing structure. Broussonetia papyrifera roots and camphor tree roots are used as monarch drugs together, and synergistically expel wind, remove cold, remove dampness and activate blood, and aim at the core pathogenesis of wind-cold-dampness arthralgia; the root medicinal materials of the whole formula walk through lower jiao and directly reach muscles and bones, are externally applied through fumigation medicated bath, avoid burdens of gastrointestinal tracts, livers and kidneys caused by oral administration, have the advantages of strengthening body resistance and harmonizing, quick response, direct action, high safety and the like, are convenient to use, and are suitable for family health care and clinical popularization.

This invention provides a traditional Chinese medicine composition for treating ulcerative colitis, belonging to the field of traditional Chinese medicine pharmaceutical technology. The composition is obtained through rational formulation based on the principles of syndrome differentiation and treatment in traditional Chinese medicine, specifically composed of Forsythia suspensa, Lilium brownii, Lysimachia christinae, Sesamum indicum, Prickly ash, Pueraria lobata, Centella asiatica, Viola yedoensis, Houttuynia cordata, Portulaca oleracea, Litsea cubeba, Cirsium japonicum, Schizonepeta tenuifolia, Morus alba root, Lophatherum gracile, Lygodium japonicum, and Capsella bursa-pastoris. This invention's composition exhibits significant anti-inflammatory and de-inflammatory effects, and can repair and improve the integrity of colonic tissue structure, enhance intestinal barrier function, and achieve both symptomatic and root-cause treatment of ulcerative colitis. Simultaneously, this invention's composition has a high efficacy and cure rate in treating ulcerative colitis, and significantly alleviates symptoms such as diarrhea, bloody stools, abdominal pain, abdominal distension, anal burning, and tenesmus, greatly reducing patient suffering.

The present invention relates to a composition for improving cardiovascular calcification using a mulberry tree extract and a method for preparing the same. The composition is prepared by collecting the fruit (mulberry), leaves (mulberry leaves), branches (mulberry branches), and root bark (mulberry bark) of the mulberry tree, extracting the fruit and freeze-drying it to produce a mulberry extract, hot-air drying the leaves, branches, and root bark, adding 20-70% ethanol corresponding to 5-50% by weight of each, extracting at 50-90°C for 2-10 hours, filtering and concentrating the extract, and freeze-drying the extract to obtain a mulberry tree extract, and dissolving each extract in distilled water at a concentration of 10-50 mg / ml to provide a composition for improving cardiovascular calcification using a mulberry tree extract and a method for preparing the same, thereby enabling relatively safe and effective improvement of cardiovascular calcification, including vascular calcification.

The invention relates to the technical field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for promoting hair growth and a preparation method and application thereof.The traditional Chinese medicine composition is prepared from raw materials including notopterygium root, pawpaw, wine-processed ligusticum wallichii, angelica sinensis, prepared rehmannia root, prepared polygonum multiflorum, wine-processed glossy privet fruit, eclipta, mulberry, herba epimedii, gastrodia elata, barbary wolfberry fruit and Chinese yam according to a specific weight ratio. The preparation method comprises the following steps: preparing pills by using tender honey and honey water as adhesives by adopting a generic or plastic process, and carrying out covering treatment to obtain the traditional Chinese medicine honeyed pill preparation. The composition aims at the pathogenesis of liver and kidney deficiency and blood deficiency and wind dryness type alopecia, and through triple compatibility of nourishing liver and kidney to treat root causes, nourishing blood and activating blood to charge its source, and dispelling wind and dredging collaterals to open its way, the composition not only supplements the material basis of hair growth, but also improves the nutritional status of hair follicles and dredges stasis of hair orifices; the traditional Chinese medicine composition effectively solves the problems that an existing traditional Chinese medicine compound is tonified but not smooth, takes effect slowly, does not have an obvious curative effect on patients with wind pathogen or blood stasis syndromes and is high in relapse rate.

The invention provides a traditional Chinese medicine composition with an effect of treating chronic pharyngitis and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from 30-50 parts of phyllanthus emblica, 20-40 parts of oroxylum indicum, 15-25 parts of terminalia chebula, 40-60 parts of roughhaired holly root, 15-35 parts of radix ophiopogonis, 5-15 parts of subprostrate sophora, 25-45 parts of selfheal, 10-30 parts of folium mori, 15-35 parts of chrysanthemum, 5-15 parts of radix scrophulariae, 8-18 parts of scaphium scaphigerum, 150-200 parts of wild chrysanthemum and 40-50 parts of honeysuckle. The preparation method comprises the following steps: (1) pretreatment and enzymolysis of rhizome raw materials; (2) whole-formula mixed extraction; (3) two-stage concentration; and (4) drying. Wild chrysanthemum focuses on clearing away heat and toxic materials and relieving swelling and pain The honeysuckle can help the wild chrysanthemum flower to clear away heat and toxic materials and dispel wind and heat. The two components are matched with the phyllanthus emblica and the like, and are prepared through an ultrasonic enzymolysis-gradient alcohol precipitation process, so that the curative effect is improved, and the recurrence rate is reduced.

This invention relates to a strain of *Sanghuang* fungus suitable for making fermented barley tea and its applications, belonging to the field of biotechnology. The *Sanghuang* fungus strain described in this invention was deposited on April 3, 2024, at the China General Microbiological Culture Collection Center (CGMCC), with accession number CGMCC No. 41280. This strain is suitable for solid-state fermentation of barley grains for making barley tea. The mycelium of this strain can penetrate the interior of barley grains, fully converting and utilizing the nutrients in the barley grains, exhibiting characteristics such as rapid growth and good appearance. The roasted *Sanghuang* barley tea has a yellow and lustrous color, overcoming the drawback of traditional barley tea being prone to causing "heatiness," possessing both the mellow aroma of barley tea and the unique refreshing aroma of *Sanghuang* fungus, and containing medicinal components of *Sanghuang* fungus. The *Sanghuang* fungus mycelium formed by fermentation and culture of this strain using barley grains as nutrients effectively solves the shortcomings of *Sanghuang* fungus being difficult to cultivate and expensive, while greatly increasing the added value of traditional barley tea.

The application discloses a gene BpMIXTA01 for regulating and controlling initial development of Broussonetia papyrifera epidermal hair as well as an expression protein and application thereof, and belongs to the technical field of plant genetic engineering. The nucleotide sequence of the gene is shown in SEQ ID NO. 1, and the amino acid sequence is shown in SEQ ID NO. 2. The gene belongs to the ninth sub-group MIXTA gene of the R2R3 MYB transcription factor family. Function verification shows that overexpression of BpMIXTA01 in Arabidopsis thaliana can significantly increase the number of epidermal hairs, and can restore the epidermal hair loss phenotype of the Arabidopsis thaliana hairless mutant, proving that BpMIXTA01 is a positive regulation factor of epidermal hair formation. The application first discloses a key regulation gene for initial development of Broussonetia papyrifera epidermal hair cells, provides an important gene resource for analyzing the molecular mechanism of epidermal hair development of woody plants, and can cultivate a hairless forage Broussonetia papyrifera new variety through genetic engineering means, and has important theoretical value and application prospect.

This invention relates to the field of traditional Chinese medicine and health food preparation technology, and discloses a selenium-enriched medicinal and edible compound preparation for improving diabetic encephalopathy, as well as its preparation and application. The preparation is made from a specific weight ratio of Codonopsis pilosula, Astragalus membranaceus, Polygonatum sibiricum, selenium-enriched Corydalis yanhusuo, and Morus alba leaves. The preparation method includes raw material pulverization, constant-temperature reflux extraction with water, filtration and purification using a 0.22μm microporous membrane, vacuum low-temperature concentration to extract, and addition of excipients to form granules, capsules, or tablets. This invention constructs a multi-target synergistic network integrating qi replenishment, blood sugar control, and nerve protection through scientific formulation. It utilizes the strong antioxidant properties of organic selenium to efficiently scavenge free radicals in the brain, improving cognitive impairment caused by diabetic encephalopathy and lowering blood sugar. Combined with a mild closed-loop process and microfiltration technology, it ensures the stability and dissolution rate of heat-sensitive active ingredients, improving the purity, safety, and batch-to-batch consistency of the preparation.

The invention discloses mulberry cytochrome P450 monooxygenase MaCYP73A16 as well as a coding gene and application thereof, and belongs to the technical field of plant genetic engineering. The amino acid sequence of the mulberry cytochrome P450 monooxygenase CYP73A16 is as shown in SEQ ID NO: 2. The nucleotide sequence of the coding gene is as shown in SEQ ID NO: 1. According to the invention, a VIGS technology is used for MaCYP73A16, so that the expression quantity of MaCYP73A16 in mulberry leaves is reduced, functional research in synthesis of mulberry flavonoids is carried out, and a regulation and control network of a synthesis pathway of mulberry flavonoids and application of the regulation and control network are improved. Important theoretical support is provided for cultivation and screening of mulberry varieties rich in flavonoid.

The application discloses a traditional Chinese medicine composition for reducing blood sugar, which is prepared from the following traditional Chinese medicinal materials in parts by weight: 20-60 parts of Astragalus membranaceus, 10-40 parts of Morus alba, 20-60 parts of Pueraria lobata, 20-50 parts of Polygonatum odoratum, 2-5 parts of bee glue and 2-5 parts of beeswax. The traditional Chinese medicine composition embodies the traditional Chinese medicine theory of syndrome differentiation and treatment, and is skillfully formulated. The traditional Chinese medicine composition plays the role of tonifying qi and nourishing yin and reducing blood sugar, and embodies the unique advantages of traditional Chinese medicine in reducing blood sugar.

The application provides a kidney-tonifying composition and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine extracts. The preparation method comprises the following steps: S1, crushing Tribulus terrestris and screening to obtain Tribulus terrestris powder; S2, taking fresh Cistanche deserticola and sodium chloride, crushing and grinding together, heating under nitrogen protection, adding methanol, concentrated hydrochloric acid and the Tribulus terrestris powder obtained in step S1, refluxing, filtering to obtain a crude extract; S3, concentrating the crude extract obtained in step S2, adjusting the pH to obtain a concentrated solution; S4, column chromatography separation of the concentrated solution obtained in step S3, concentrating and drying the eluent to obtain a kidney-tonifying traditional Chinese medicine extract. The application further provides a kidney-tonifying composition, which is prepared from the kidney-tonifying traditional Chinese medicine extract and Myristicae Semen, Polygalae Radix, Morus alba fruit, and Radix Glycyrrhizae. The composition has good application prospect due to the good kidney-tonifying effect of the monarch, the ministers and the aids.

The invention discloses multi-herb hair-blacking, hair loss-preventing, eye-nourishing and skin-care powder and a preparation method of the multi-herb hair-blacking, hair loss-preventing, eye-nourishing and skin-care powder. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 15-25 parts of radix polygoni multiflori preparata, 10-20 parts of semen sesami nigrum, 8-15 parts of fructus ligustri lucidi, 8-15 parts of herba ecliptae, 10-20 parts of fructus lycii, 5-12 parts of radix angelicae sinensis, 5-10 parts of rhizoma chuanxiong, 8-15 parts of fructus mori, 5-10 parts of semen cuscutae, 5-10 parts of fructus rubi, 5-10 parts of folium mori, 5-10 parts of flos chrysanthemi, 5-8 parts of radix paeoniae alba and 3-6 parts of pearl powder. Dendrobium officinale and herba ecliptae extracts are innovatively added to form synergistic interaction with an original formula, the yin nourishing and heat clearing effects of dendrobium officinale enhance the overall oxidation resistance of the raw materials, and polysaccharide components of dendrobium officinale can promote hair follicle cell proliferation; the herba ecliptae extract enriches effective components and strengthens the adjusting effect on the scalp microenvironment, the problems that a traditional formula is mild in effect and slow in effect taking are solved, meanwhile, the product integrates the multiple effects of blackening hair, preventing hair loss, nourishing eyes and protecting skin, and the defect that an existing product is single in function is overcome.

The invention provides a traditional Chinese medicine composition for treating alopecia, a traditional Chinese medicine preparation and application thereof. The traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials in parts by weight: 1-50 parts of radix polygoni multiflori preparata, 1-50 parts of fructus ligustri lucidi, 1-50 parts of herba ecliptae, 1-50 parts of rhizoma polygonati, 1-50 parts of mulberries, 1-50 parts of radix angelicae sinensis, 5-100 parts of radix salviae miltiorrhizae, 1-50 parts of rhizoma chuanxiong and 1-50 parts of flos carthami. The traditional Chinese medicine composition can inhibit apoptosis, prolong the hair growth cycle and promote hair growth.