696 results about "Cordyceps pruinosa" patented technology

The invention discloses a method for culturing selenium-enriched Cordyceps militaris, which is to increase the selenium content in a culture medium to 50mg/L by using organic selenium yeasts instead of inorganic seleninic acid and sodium selenite, which infect the growth of hyphae, so as to ensure the selenium content in the cultured selenium-enriched Cordyceps militaris reaches 35 to 50mg/L. In the invention, the organic selenium yeasts which exert the lest inhibition effect on the growth of the Cordyceps militaris are adopted to increase the selenium content in the culture medium to 50mg/l, the selenium content in the cultured selenium-enriched Cordyceps militaris reaches 35 to 50mg/kg, which is 2 times higher than that of the Cordyceps militaris cultured in a culture medium added with inorganic selenium, and the yield of Cordyceps militaris is high.

The present invention relates to a cordyceps sinensis powder tablet and a preparation method thereof, which pertains to the field of medicines and health products. The technical problem the present invention aims at providing a tablet containing cordyceps sinensis medicinal powder and no auxiliary material; the appearance, shape and harness of the tablet is consistent with the tablet quality standard. The cordyceps sinensis powder tablet only adopts cordyceps sinensis powder with the water content of 8 to 18 percent and the granule diameter of 1 to 150mum; no auxiliary material is added in the preparation process and the cordyceps sinensis powder is the only component. The aim of direct tablet forming can be achieved by controlling the water of the powder or by the process of second tabletting or dry granule tabletting. The process ensures that the tablet appearance is good; pockmark surface rate and fracture rate are low; tablet harness, disintegration rate and friability are consistent with the tablet quality requirement; the harness can also ensure that the tablet can not fracture in the preparation process when coating and film covering is carried out in the later stage.

The invention discloses a culture medium to ferment and manufacture Cordyceps sinensis mycelium, which consists of bevel culture medium and fermentation culture medium, wherein different culture mediums are adopted in different stages to ensure plain growth of the Cordyceps sinensis and equal quality of fermented and natural Cordyceps sinensis, which modifies the product quality and improves the production with certain effect. The invention supports the character of nourishment with natural Cordyceps sinensis, which is fit for industrial manufacturing need.

A technique for culturing cordyceps by insect includes such steps as collecting fresh wild cordyceps, tissue separation to obtain its bacterial strain, reproduction, culturing slant strain and liquidbacteria, choosing host insect or host insect surrogate, spraying bacterial liquid for infecting the host insect, and culturing in the condition stimulating the wild environment. Its advantages are low cost and high effect.

The invention relates to cordyceps sinensis nano powder, cordyceps sinensis freeze-dried nano powder tablet and a preparation method of the cordyceps sinensis freeze-dried nano powder tablet, belonging to the field of medicaments and health care products. The cordyceps sinensis freeze-dried nano powder tablet is obtained by carrying out freeze-drying on the cordyceps sinensis nano powder only containing cordyceps sinensis total component or is obtained by smashing a freeze-dried product into coarse powder and then pressing the coarse powder into tablets, wherein particle size of the cordyceps sinensis nano powder is 10-800nm. Under protection of a jacket cooling device, a high-energy nano ball mill is adopted for smashing cordyceps sinensis into nanoscale micro powder, the particle size of the smashed cordyceps sinensis is 10-800nm, the smashed cordyceps sinensis nano powder is added into appropriate amount of purified water to be made into cordyceps sinensis nano powder homogeneous size, vacuum freeze-drying is directly carried out to obtain freeze-dried tablets, or freeze-dried products with different moisture contents are made, then the cordyceps sinensis nano powder is added and is pressed into tablets, and packaging is carried out to obtain the cordyceps sinensis freeze-dried nano powder tablet. The cordyceps sinensis freeze-dried nano powder tablet disclosed by the invention has no tonic loss or damage, good taste and uniform and stable product quality, can be rapidly disintegrated, has high human bioavailability and is convenient to carry and use.

The invention belongs to the field of Chinese materia medica preparations and relates to an anti-hair loss and hair growing traditional Chinese medicine composition and a preparation method of the anti-hair loss and hair growing traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by weight: 50-180 parts of ginseng, 50-180 parts of cacumen biotae, 20-120 parts of polygonum multiflorum, 10-70 parts of liquorice, 10-50 parts of old ginger, 50-180 parts of drynaria rhizome, 30-120 parts of eclipta alba, 5-50 parts of cordyceps sinensis and 20-80 parts of fructus ligustri lucidi. Products of the traditional Chinese medicine composition has characteristics of treating both symptoms and root causes, as well as various alopecias, and has the advantages of explicit therapeutic effects, wide treating faces, excellent effects on patents, rapid effect production, short course of treatment, high product safety and small toxic and side effects on human bodies. After checking, an effective rate of a prescription on sebrrheic alopecia can achieve 94.3%, and an effective rate of the prescription on alopecia areata can achieve 98%.

The invention discloses a preservation method of cordyceps sinensis, which comprises the steps of sequentially cleaning the head part, stroma and polypide of the cordyceps sinensis by use of linear running water; soaking the cleaned cordyceps sinensis in a 0.9% acid sodium chloride for 5-8 minutes, and draining; performing quick cooling treatment on the cordyceps sinensis for 5-12 hours at -75 DEG C; putting the cordyceps sinensis after the quick cooling into a vacuum refrigeration box at (-5)-(-25) DEG C, and starting the refrigeration gas self-control equipment in the refrigeration box, wherein the refrigeration gas self-control equipment controls a gas pump to introduce and/or extract oxygen, nitrogen and carbon dioxide gas into/out of the refrigeration box. By adopting the preservation method disclosed by the invention, the cordyceps sinensis can meet the sanitary requirement of direct eating; after long-time storage, the nutritional ingredients and activity of the cordyceps sinensis are barely lost.

An artificial culture method for north cordyceps sporophores includes such steps as selecting excellent strains (cordyceps body), separating, screening, purifying to obtain high-yield spawns, adding them to culture medium in pp bottles, culturing sporophores under light radiation and temp contron condition, inoculating into living silkworm chrysalis, and rejuvenescent culture to obtain fresh living cordyceps product. Its advantages include big body (3-4 mm X 4.5-8.5cm), higher contents of cordyceptic extract (polyose) and SOD, and low cost.

The invention relates to health-care liubao tea combined with tea and Chinese herbal medicines by adopting a fermentation technology, and a preparation method thereof. The health-care liubao tea is prepared from the following raw materials in parts by weight: 20-60 parts of coronoid process cysticercosis grass bacterium, 800-2300 parts of tea, 0.5-3kg of cordyceps sinensis, 60-120 parts of ganoderma lucidum antler, 60-120 parts of pseudo-ginseng, 120-250 parts of angelica sinensis, 90-180 parts of rhizoma zingiberis, 80-160 parts of processed folium artemisiae argyi, 80-120 parts of cedar leaves, 30-90 parts of liquorice, and 90-130 parts of jasmine. The preparation method of the tea comprises the following steps: firstly, preparing the coronoid process cysticercosis grass bacterium and ganoderma lucidum antler sporocarp; taking the cordyceps sinensis, the ganoderma lucidum antler, the pseudo-ginseng, the angelica sinensis, the rhizoma zingiberis, the processed folium artemisiae argyi, the cedar leaves, the liquorice and the jasmine to decoct by water, so as to prepare clear cream; taking the coronoid process cysticercosis grass bacterium and the liubao tea to carry out pile fermentation, so as to prepare 'golden flower' liubao tea; stirring and mixing the liubao tea with the clear cream; and sterilizing, disinfecting, drying, checking and warehousing. The tea has the health-care functions of enhancing the immunity, and resisting fatigue and ageing; excellent quality and mouthfeel of the 'golden flower' liubao tea are achieved.

The invention discloses a method for extracting melanin from cordyceps militeris fungus fermentation broth. The method includes the following steps: mycelium is separated from the cordyceps militeris fungus fermentation broth, and the fermentation broth is acidized to obtain melanin crude extract after the sediment is collected. The melanin crude extract is hydrolyzed by hydrochloric acid to eliminate protein impurities, and is repeatedly scrubbed by organic solvent and dissolved by alkaline solution, and is acidized to form sediment for purification, and then the chloride ions are eliminatedby deionized water through repeated scrubbing, finally the cordyceps militeris melanin end product is obtained after drying. The melanin prepared by the invention has similar properties with melanin CAS: 8049-97-6 sold by Sigma Corporation. Both two types of melanin can dissolve in alkaline solution, cannot dissolve in organic solvents, such as water, ethanol, acetone, chloroform and hexane, completely become sediment when pH value is less than 3 and can fade under the effect of strong oxidizer; the ultraviolet visible light area scan map includes a curvature with reducing absorbance along with the increasing of wavelength, and strong absorbing bands are respectively near 340cm-1 and 1602cm-1 in the infrared spectrum.

The invention discloses a traditional Tibetan medicine for treating cough and a preparation method thereof. The traditional Tibetan medicine for treating the cough is composed of active ingredients or is composed of the active ingredients and pharmaceutically acceptable auxiliary materials, wherein the active ingredients are prepared from liquorice, phyllanthus emblica, common vladimiria root, sea buckthorn paste, cordyceps sinensis and bulbus fritillariae cirrhosae in certain weight proportion. The traditional Tibetan medicine for treating the cough disclosed by the invention can be preparedinto any common oral administration dosage form. The traditional Tibetan medicine for treating the cough disclosed by the invention has the effects of relieving cough and reducing sputum, clearing throat and relieving sore throat, invigorating blood circulation and removing blood stasis, moistening lung and diminishing inflammation. The traditional Tibetan medicine for treating the cough disclosed by the invention is used for treating cough, vomiturition, thick and excessive phlegm, bronchitis, lung infection and throat fatigue, hoarseness, chronic pharyngitis and asthma which are caused by cold.

The invention provides a mitochondrial gene sequence for identifying authenticity and quality of Cordyceps sinensis and an operation method thereof. According to the method, differences of mitochondrial genes between ghostmoth and other lepidopteran insects are compared and thus high-variability areas can be searched. Specific primers of the ghostmoth are designed to obtain sequences of corresponding sections of mitochondria of host insects; if a nucleotide difference rate is less than 1-1.5 %, the insects are determined to be a same species but different individuals, and if the nucleotide difference rate is more than 6 %, the insects are determined to be a same genus but different species, thereby not only identifying whether to-be-detected samples are the Cordyceps sinensis formed with Hepialus larvae as the host insects, but also determining producing areas of the to-be-detected samples, and thus determining the authenticity and grades of the to-be-detected samples The method is simple in steps, easy to operate, and few in sample amount, and can minimize sample loss. According three pairs of the specific primers provided by the invention, the authenticity and the grades of the samples can be rapidly and conveniently detected through detecting whether the samples have same or similar nucleotide sequences as well as similarity of the nucleotide sequences.

The invention discloses a composition capable of invigorating qi for ascending and enhancing immunity, and a preparation method thereof. The composition comprises the following ingredients: 30-40g of ginseng, 10-15g of cordyceps sinensis or cordyceps militaris, 2-3g of lycopene, 10-15g of lucid ganoderma, 10-15g of morinda officinalis, 10-15g of barbary wolfberry fruit, 50-70mcg of organic selenium, 550-650mcg of vitamin A, 5-6mcg of vitamin B, 130-140mcg of vitamin C, and 5-8g of other auxiliary materials. According to the composition and the preparation method disclosed by the invention, the extracts of the used raw materials are processed by a nanometre wall-breaking technology into micromolecules capable of being absorbed by a human body, thus greatly increasing the comprehensive utilization rate of precious food materials, providing scientific basis for industrialized and standardized production, enabling the product quality to be controllable and adequately exerting the curative effect. The composition disclosed by the invention has the functions of invigorating qi for ascending, enhancing immunity, resisting oxidation and ageing, relieving physical fatigue, assisting to improve memory, tonifying kidneys, and the like. The product is easily acceptable in taste, simple and natural in colour, beautiful and graceful, and suitable for all ages.

The invention discloses healthcare food, and particularly relates to cordyceps militaris nourishing paste and a preparation method thereof. The cordyceps militaris nourishing paste is prepared from the following raw materials in parts by weight: 60-140 parts of cordyceps militaris, 60-100 parts of longan pulp, 80-120 parts of Chinese date, 60-100 parts of walnut kernel, 50-70 parts of fructus lycii, 20-30 parts of honey, 40-60 parts of high fructose corn syrup and 20-25 parts of sodium carboxymethyl cellulose. The preparation process of the cordyceps militaris nourishing paste comprises the steps of grinding, biological enzymolysis, solid-liquid separation, ultrafiltration, vacuum concentration and the like. Pharmacodynamic tests prove that the product can obviously improve the body immunity and is a nourishing product with a healthcare function and suitable for various people with low immunity.

The invention discloses a Cordyceps sinensis mutant strain for production of Cordyceps sinensis mycelia and relates to the field of application of a food microorganism technology. The mutant strain is collected in CCTCC (China Center for Type Culture Collection) in Wuhan, China on Jan. 23rd, 2015 with the number of CCTCC M 2015064 and the recommended Latin name of Cordyceps sinensis CCTCC M 2015064. In order to avoid use of toxic and harmful chemical mutagens and a genetic engineering method which is not recognized by the public in the food field, an ultraviolet physical mutagenesis technology is considered to be simple and easy, so that the ultraviolet mutagenesis method is adopted for mutagenesis, excellent characters of the novel Cordyceps sinensis strain are guaranteed through a series of screening methods in aspects of stability, hereditary and the like, and a strain basis for obtaining better-quality Cordyceps sinensis mycelium raw material, which can be used for producing healthy food, for industrial efficient fermentation of low-cost and novel rice bran and wheat bran complete liquid culture media to which cysteine hydrochloride and sodium copper chlorophyllin are added.

The invention relates to a traditional Chinese medicine for treating pneumoconiosis and drug-tolerant pulmonary tuberculosis and a preparation method thereof, which improve and eliminate the pathological residues through the synergy of all medicine according to the dialectic theory of the traditional Chinese medicine, thus leading the body fluid and other organic substances to be transferred to the lung and achieving the effect of rapidly relieving and getting rid of disease and health recovery. The traditional Chinese medicine prepared in the invention comprises the raw materials with weight ratios as follows: 8-12 parts of cordyceps sinensis, 3-7 parts of tokay, 250-350 parts of Pinellia tuberifera, 25-300 parts of Chinese wolfberry, 250-350 parts of Bletilla hyacinthina reichb, 15-50 parts of balloon flower, 3-20 parts of mulberry bark, 3-20 parts of shizandra berry, 250-350 parts of liquorice root, 45-55 parts of bulb of fritillary, 15-25 parts of almond, 15-25 parts of Tatarian Aster Root, 25-35 parts of coltsfoot, 15-25 parts of Blackberrykiky Rhizome, 8-12 parts of root of straight ladybell, 8-12 parts of dried orange peel, 8-12 parts of sugared sesame powder, 10-20 parts of polygala tenuifolia, 8-12 parts of red tangerine peel, 15-25 parts of ginkgo seed, 15-25 parts of trichosanthes kirilowii shell, 15-25 parts of white muscardine silkworm, 8-12 parts of placenta hominis, 4-8 parts of Scutellaria baicalensis, 8-12 parts of radix peucedani, 8-12 parts of perilla seed.

A process for extracting complex cordycepin includes such steps as immersing the powdered cordyceps in water for 8-14 hr, extracting by alcohol or by decocting and alcohol deposition, filtering to obtain liquid medicine, concentrating reflux of alcohol, eluting with ionic column, concentrating, cold storage at 0 deg.C for 24 hr, crystallizing, and recrystallizing with n-butanol. The cordycepin contains 2'-deoxyadensine and 3'-deoxyadenosine compound and has high anticancer action.