258 results about "Cordyceps sp." patented technology

The invention relates to a cordyceps militaris cultivation device which comprises a cultivation frame and a cultivation box, the cultivation frame comprises a plurality of sets of independent cultivation chambers, and each set of cultivation chambers are divided into cultivation cavities of a plurality of levels according to cultivation stages; an inoculated culture medium is contained in the culture box; each group of cultivation chambers is internally provided with an independent transfer mechanism, the transfer mechanisms control the cultivation boxes to gradually transfer from low-grade cultivation cavities to high-grade cultivation cavities according to needs, each cultivation cavity is internally provided with an independent illumination system, and the cultivation cavities of the same grade are internally provided with the same ventilation system; the cultivation boxes in the static state and the corresponding cultivation cavities form closed or sealed spaces; efficient partitioned independent cultivation management is achieved, environment parameters such as illumination, temperature and humidity can be better controlled on the basis of the growth stage of mycelia, high-yield and high-quality cordyceps militaris can be obtained, and the growth processes of the mycelia in different cultivation boxes can be compared and observed more visually.

The invention discloses a method for preparing a cordyceps culture medium by taking polygonatum kingianum as a culture medium, and relates to the technical field of culture medium preparation. The method comprises the following steps: performing enzymolysis treatment on a polygonatum kingianum raw material to obtain enzymatic hydrolysate rich in micromolecular nutrition; active components of polygonatum kingianum are extracted to prepare microcapsules with response release characteristics; preparing at least two kinds of 3D biological printing ink by utilizing the enzymatic hydrolysate and a component containing the microcapsule and a polygonatum kingianum material which is not subjected to enzymolysis; the ink is constructed into a three-dimensional culture medium with a layered or gradient structure layer by layer through a 3D printing technology and is solidified, the culture medium prepared by the method can realize gradient distribution of nutrients and programmed release of active ingredients, and an optimized microenvironment is provided for growth of cordyceps sinensis, so that the culture efficiency, yield and quality of cordyceps sinensis are effectively improved.

The invention provides a composition for improving a barrier function and application thereof, and relates to the technical field of cell injury nursing. Gamma-aminobutyric acid (GABA) and cordyceps militaris fermentation filtrate (FCM) are used for treating barrier damage for the first time. Specifically, the combination of the gamma-aminobutyric acid and the cordyceps militaris fermentation filtrate can significantly improve damage of an epithelial mechanical barrier and an immune barrier caused by external stimulation, so that the epithelial barrier function can be prevented and improved from multiple dimensions.

The invention relates to the technical field of mycelium culture, and provides a culture method and application of cordyceps militaris mycelium with high selenium content and high cordycepin content. The culture method comprises the following steps: inoculating cordyceps militaris mycelia into a liquid culture medium, and carrying out shake culture for 4-7 days to obtain cordyceps militaris liquid seeds; adding a plant selenium source into the solid culture medium, sterilizing to obtain a cordyceps militaris selenium-rich solid culture medium, adding the cordyceps militaris liquid seeds into the cordyceps militaris selenium-rich solid culture medium, and continuously culturing for 30-40 days to obtain the high-selenium and high-cordycepin cordyceps militaris mycelium. According to the culture method, the steps are simple and convenient, the raw materials are cheap and safe, the total selenium content of the produced mycelium is 0.76-191.45 mg / kg, the organic selenium content is more than 99%, the cordycepin content is 17707.3-24769 mg / kg, the content of various effective components such as the total selenium, the organic selenium and the cordycepin is outstanding, the yield is high, standardized popularization and application of the selenium industry in multiple fields are facilitated, and the wide market prospect is achieved.

This invention discloses a protein-polysaccharide ternary nanoparticle loaded with cordycepin, its preparation method, and its applications. The invention employs a layer-by-layer self-assembly method to modify the surface of zein nanoparticles. Since zein has a positive surface charge, the first layer modification uses the anionic polysaccharide sodium alginate for electrostatic bonding, and the second layer modification uses the cationic polysaccharide chitosan, constructing positively charged ternary composite nanoparticles. These nanoparticles have small particle size, high encapsulation efficiency, high drug loading capacity, and a sustained-release effect, significantly reducing cytotoxicity and significantly improving the therapeutic effect on osteoarthritis. This invention develops a novel cordycepin formulation, overcoming the limitations of cordycepin's clinical use.

The invention discloses application of cordyceps javanica Bd01 and a dispersible oil suspending agent thereof to prevention and control of spodoptera frugiperda, and relates to the technical field of biology. The research finds that the cordyceps javanica Bd01 has a strong infection lethal effect on larvae of spodoptera frugiperda at all ages, the pupation rate and eclosion rate of the larvae can be remarkably reduced, and the breeding cycle of pests can be effectively blocked. The invention further develops a dispersible oil suspending agent, and the suspending rate is effectively improved through formula optimization. The dosage form takes soybean oil as a dispersion medium, does not contain harmful solvents such as methylbenzene, is free of dust pollution and is friendly to operators and the environment, and ascorbic acid is added to improve the ultraviolet resistance of spores and prolong the effective period of the pesticide effect. In addition, the preparation also has a certain control effect on caffeinidae, is wide in application scene, provides a new scheme for green control of spodoptera frugiperda, solves the problems of chemical pesticide resistance and residue, and accords with the development requirements of green agriculture.

The invention discloses a composition for resisting altitude stress and improving hypoxia tolerance, and belongs to the field of nutritional health-care food and functional compositions. The composition comprises the following components in parts by mass: 20-60 parts of beet root powder, 10-50 parts of cordyceps militaris powder, 5-40 parts of astragalus membranaceus powder, 0.5-5 parts of ginseng powder and 1-10 parts of Chinese wolfberry fruit powder. The composition can be prepared into foodstuffs such as soft sweets, tablets, powder, drinks, capsules and the like or other nutritional supplement forms, so that the problems of single effect, indefinite action mechanism and poor compliance of the existing product are solved, and multi-target regulation of hematopoiesis enhancement, energy metabolism improvement, oxidative stress inhibition and circulation improvement is realized.

This invention discloses a highly active compound health supplement made from Cordyceps sinensis, Artemisia argyi, and rhubarb, and its preparation method, belonging to the field of health food and pharmaceutical preparation processing technology. The method includes: adding artificial Cordyceps sinensis ultrafine powder, prepared Rhubarb tanguticum fine powder, Artemisia argyi leaf extract, microcrystalline cellulose PH102, and maltodextrin into a mixer and premixing at 25-35 rpm to allow the powder to adhere to the surface of the excipients; after tableting, the tablets are subjected to ultra-high pressure treatment at 350-380 MPa. This invention achieves uniform distribution and performance optimization of the formulation components without damaging the activity of heat-sensitive components through precise coupling of premixing strength and ultra-high pressure modification parameters. Experiments show that the obtained formulation has an adenosine retention rate ≥96%, a dissolution rate ≥85% after 5 minutes, and excellent moisture resistance and mechanical strength, solving the technical problems of large activity loss, easy moisture absorption, and slow dissolution in traditional formulations.

The invention relates to a lycium barbarum fermented product with a liver protection function as well as a preparation method and application thereof, and belongs to the technical field of fermentation. The fermentation liquor is prepared by taking a specific traditional Chinese medicine compound consisting of radix puerariae, semen hoveniae, fructus lycii, rhizoma polygonati, flos chrysanthemi, pericarpium citri reticulatae and cordyceps militaris as a matrix through a double-bacterium synergistic fermentation process. The preparation method comprises the following steps: firstly, pre-fermenting a compound extract by using Akkermansia muciniphila bacteria, enriching propionic acid and optimizing the matrix; the preparation method comprises the following steps: carrying out primary fermentation by using lactic acid bacteria combined with Lactobacillus paracasei E10, L. paracasei JN-1 and L. paracasei JN-8 (in a volume ratio of 3: 3: 2), and carrying out secondary fermentation by using lactobacillus combined with Lactobacillus paracasei E10, L. paracasei JN-1 and L. paracasei JN-8 (in a volume ratio of 3: 3: 2). The traditional Chinese medicine composition realizes double synergy of efficient conversion of traditional Chinese medicine active ingredients and intestinal-hepatic axis regulation and control, and is suitable for prevention and adjuvant therapy of alcoholic liver injury and non-alcoholic fatty liver disease.

To provide an endoplasmic reticulum stress suppressing composition and a liver function improving composition.SOLUTION: A composition for suppressing endoplasmic reticulum stress and / or a composition for improving hepatic functions, comprising one or more plants selected from the group consisting of Plantago asiatica, Hamilton's spindle tree, panicled hydrangea, Japanese plum yew, Japanese mallotus, and Papaver rhoeas, and / or an extract thereof.SELECTED DRAWING: None

1. Name of the product for this design: Packaging Box (Snow Lotus Cordyceps Mixture). 2. Application of this design: This design is intended for use in pharmaceutical packaging. 3. The key design features of this product are the combination of shape and pattern. 4. The image or photograph that best illustrates the design's key points: a 3D model.

This invention discloses a method and product for preparing Pien Tze Huang herbal wine fermented on Cordyceps militaris culture medium, belonging to the field of health wine brewing technology. This method uses Cordyceps militaris culture medium (SCM) and Pien Tze Huang herbal wine (GFE) as raw materials, and prepares a health wine with hypoglycemic and antioxidant effects through a complex fermentation process including raw material pretreatment, enzymatic hydrolysis, yeast activation, anaerobic fermentation, and post-treatment. It aims to solve the problems of low raw material utilization, low active ingredient content, and insufficient antioxidant activity in existing technologies. Pretreatment employs ultrasonic extraction. Fermentation conditions are anaerobic fermentation at 28℃ for 18 days, with 3% sugar supplementation every 2 days, controlling the alcohol content at 6%-10% vol, and preferably using an SCM:GFE ratio of 2:1. The resulting product has an alcohol content of 8% vol, is rich in total phenols and total flavonoids, has an α-glucosidase inhibition rate of 82.6%, a DPPH free radical scavenging rate of 78.3%, and a FRAP value of 82.6 mM Fe. 2+ Equivalents / mL, with a harmonious flavor and significant health benefits, provide an effective way for the comprehensive development of Cordyceps militaris and Pien Tze Huang.

The application discloses a flowerpot filling system based on industrialized production of Cordyceps flower, and relates to the technical field of mushroom cultivation.The flowerpot filling system based on industrialized production of Cordyceps flower comprises an equal-amount discharging and laying mechanism and a compaction and leveling mechanism, the compaction and leveling mechanism comprises a placing cavity, a planting flowerpot is placed in the placing cavity, and the equal-amount discharging and laying mechanism is arranged on one side of the compaction and leveling mechanism.Through the arrangement of the compaction and leveling mechanism, the compacting treatment is performed on the laid culture medium raw materials, the compacting work of the culture medium can be quickly and uniformly completed, the production efficiency is higher compared with artificial compacting treatment, and the mechanical compacting can ensure that the culture medium in each flowerpot reaches the same compactness, helps to ensure the consistency of product quality, the accurate control of the compacting work can reduce the waste of the culture medium raw materials, realizes the reasonable utilization of resources, and reduces the cost.

The invention discloses an immunomodulatory composition based on a cordycepin-selenium nano chelate and a preparation method thereof, and belongs to the technical field of biological medicines.The immunomodulatory composition is characterized in that 15-25 nm zero-valent selenium nano particles are chelated through hydroxyl of cordycepin and N7 site bidentate coordination, and a stable five-membered ring structure with the molar ratio is formed; the preparation method comprises the following steps: reducing sodium selenite in an inert atmosphere to generate selenium colloid, chelating the selenium colloid with a cordycepin ethanol solution, and carrying out ultrafiltration and freeze-drying to obtain the product. The invention aims to solve the problems of fuzzy structure, inconsistent batch, uncontrollable immunomodulatory function and the like caused by non-specific mixing in the prior art, and the composition can bidirectionally regulate and control IRF3 pathways, promote polarization of M2 type macrophages and proliferation of Treg cells, and has a clear immunomodulatory mechanism and excellent stability.

The invention discloses an application of a cordyceps militaris germ extract in preparation of an anti-tobacco mosaic virus pesticide, and belongs to the technical field of pesticides. The cordyceps militaris embryo extract has the effect of inhibiting activity on TMV, provides a new way for efficient utilization of cordyceps militaris embryos, promotes high-quality development of the cordyceps militaris cultivation industry, and has important production value and practical significance.

The invention provides a sensor-based cordyceps militaris fermented beverage fermentation evaluation method and system, and relates to the technical field of fermentation engineering.Multi-frequency ultrasonic signals are transmitted and received through an ultrasonic transceiver array deployed on the outer wall of a fermentation tank; and reconstructing the signal into an acoustic parameter three-dimensional distribution image of the fermentation liquid in the fermentation tank by utilizing a tomography algorithm. And based on a pre-established mapping relation, mapping the acoustic parameter three-dimensional distribution image into three-dimensional distribution of the fermentation state parameters. And finally, based on the three-dimensional distribution of the fermentation state parameters, evaluating the overall real state of the internal environment of the fermentation tank to obtain spatial non-uniformity quantitative data of the internal environment of the fermentation tank, and generating an instruction for regulating and controlling the fermentation process according to the data. The method effectively solves the problem that monitoring of a traditional local sensor is not accurate due to non-uniformity of the internal environment of a large industrial fermentation tank in the prior art.

The invention provides a composition for building bodies and improving sexual functions as well as a preparation method and application of the composition, and relates to the technical field of medicinal and edible traditional Chinese medicines and food resources. The composition is prepared from the following components in parts by mass: 20 to 50 parts of oyster peptide, 5 to 20 parts of maca extract, 4 to 18 parts of fructus lycii extract, 4 to 18 parts of herba cistanche extract, 1.5 to 9 parts of radix ginseng extract, 0.3 to 2 parts of cordyceps militaris extract, 0.3 to 2.5 parts of rhizoma polygonati extract and 0.6 to 1.5 parts of vitamin C. Under the synergistic effect of all the components in the composition formula, the antioxidant activity can be remarkably improved, the effects of resisting fatigue and strengthening the physique are achieved, then the composition is beneficial to the male sexual function in multiple ways, cavernosum smooth muscle relaxation and penile erection are promoted, the effects of building the body and improving the sexual function are achieved, and the composition especially plays an important role in improving the sexual function of middle-aged and elderly people.

The invention provides a recombinant cordyceps militaris strain with high yield of beta-glucan as well as a construction method and application of the recombinant cordyceps militaris strain, and belongs to the technical field of bioengineering and genetic breeding of edible fungi. According to the invention, a cordyceps militaris CmGls super-safe overexpression vector is constructed through a CRISPR-Cas9 technology, and then the cordyceps militaris CmGls super-safe overexpression vector is transferred into cordyceps militaris to obtain a recombinant cordyceps militaris strain with high yield of beta-glucan. According to the recombinant cordyceps militaris strain, membrane binding type beta-1, 3-glucan synthetase gene CmGls is accurately inserted into a safe port site CmSh1 of a cordyceps militaris genome, compared with a wild type cordyceps militaris strain, the growth rate of the recombinant cordyceps militaris strain is remarkably increased by 15% or above, and yellow phenotype and cell wall stress resistance are remarkably enhanced; after 6 days of submerged fermentation, the mycelium amount and the extracellular beta-glucan yield are respectively improved by more than 10%, and the strain has good application in improving beta-glucan synthesis.

The invention provides a preparation method of a seed-dressing agent for preventing rice insect pests and a product thereof. According to the method, the survival rate of cordyceps javanica during long-term storage of the seed dressing agent is improved through gelation of exosporin, addition of pyroclastic tuff and addition of casein; the thallus loading capacity of the seed dressing agent cordyceps javanica is improved through alkali treatment, negative pressure treatment, pressurized circulating filtration loading and lactose addition; by adding the binding agent prepared from the corn husks and adding the exowall essence gel prepared from the pollen, the falling rate of the seed dressing agent is reduced; the thallus slow-release capability of the seed dressing agent is improved by adding the exowall element gel prepared from the pollen; the prevention effect on rice planthoppers is improved through the insect manure, and insect pests are prevented.

The invention discloses a cordyceps militaris and pholiota nameko coarse cereal flour pancake and a making method thereof. Cordyceps militaris, pholiota nameko, corn grits, rice, soybeans and table salt are used as raw materials, a proper amount of water is added, and the raw materials comprise 17-19 jin of corn grits, 8.5-10 jin of rice, 0.5-1.5 jin of soybean meal, 1-2 jin of cordyceps militaris, 1-2 jin of pholiota nameko and 0.5-1.5 jin of table salt. Artificially cultured cordyceps sinensis mycelia or sporocarps are selected as the cordyceps militaris; the preparation method comprises the following steps: cleaning fresh cordyceps militaris and pholiota nameko with bubbles, killing at high temperature, quickly freezing, refrigerating, cutting into small blocks, uniformly stirring with the cured corn grit, rice, soaked corn grit, rice, soybean meal and salt by adding water, pulping to prepare pancake paste, fermenting, and putting into a pancake machine to process the pancake. The pancake made by the method is good in texture, fine and smooth in taste and comprehensive in nutrition, retains multiple nutritional health-care components of food materials, is homologous in medicine and food, is a novel nutritional delicious food, and is easy to industrially produce.

The invention discloses a composition for comprehensive conditioning of an internal environment, which comprises the following components in parts by weight: 1000-1200 parts of alpha-linolenic acid, 100-300 parts of cordyceps militaris powder, 50-150 parts of oyster powder, 50-150 parts of ginseng powder, 50-150 parts of pueraria peptide, 50-150 parts of fresh lalang grass rhizome powder and 50-150 parts of polygonatum odoratum powder. Wherein the purity of the alpha-linolenic acid is not lower than 80%. According to the invention, high-purity alpha-linolenic acid and six specific medicinal and edible components are scientifically proportioned to construct a multi-level synergistic system, and all the components complement and synergism on a plurality of targets such as lipid lowering, circulation promoting, sugar stabilizing, acid discharging, repairing and the like, so that comprehensive conditioning on disorder of multiple indexes such as blood fat, blood sugar, uric acid, blood pressure and the like is realized; the limitation of a single component or a simple compound product is broken through, and the comprehensive synergistic conditioning of the internal environment is realized; all the components are selected from a medicinal and edible substance catalog, so that the traditional Chinese medicine composition is safe and mild, meets the physique requirements of Chinese people on warm nourishing and conditioning, gives consideration to conditioning and repairing, and is high in adaptability.

The invention discloses sea-buckthorn, radix astragali and yeast beta-glucan granules and application thereof, and relates to the technical field of food health care, and the sea-buckthorn, radix astragali and yeast beta-glucan granules are prepared from the following raw materials: sea-buckthorn, radix astragali, yeast beta-glucan, American ginseng, radix salviae miltiorrhizae, fructus lycii, flos sophorae, fructus crataegi, xylitol, erythritol, cordyceps militaris, inonotus obliquus, radix polygonati officinalis, rhizoma dioscoreae, radix ophiopogonis and fructo-oligosaccharide. According to the invention, a three-dimensional efficacy system of immune activation, inflammation inhibition and intestinal repair is constructed through scientific proportioning of raw materials such as sea-buckthorn, astragalus membranaceus, yeast beta-glucan, cordyceps militaris and inonotus obliquus. The core components have a synergistic effect, so that not only can the activity of immune cells be activated and the immunity of the organism be improved, but also the release of inflammatory factors can be inhibited, the inflammatory response can be relieved, and meanwhile, the intestinal beneficial bacteria can be proliferated, the intestinal mucosa can be repaired and the intestinal micro-ecology can be improved. Compared with traditional medicinal and edible granules with a single effect, the product can meet the health requirements of people with different constitutions and is richer in adaptive scene.

This invention belongs to the fields of genetic engineering and microbial technology, specifically relating to a yeast quorum sensing dynamic regulation system, method, and its applications. This invention successfully constructs a functional, bacterial-derived RpaI / RpaR quorum sensing system in yeast for the first time. The constructed yeast quorum sensing dynamic regulation system possesses advantages such as low background leakage, high sensitivity, and wide dynamic range. By flexibly coupling the core system with a signal amplification module (Gal4) and a signal conversion module (CRISPRi), a bifunctional cascade platform integrating activation and inhibition is constructed, achieving multidimensional and precise dynamic regulation of metabolic pathways. Furthermore, the system has been applied to the biosynthesis of several important compounds, including cordycepin, geraniol, and 3-hydroxypropionic acid, significantly increasing yields and effectively balancing the conflict between cell growth and product synthesis, demonstrating its great potential as a universal dynamic regulation tool.

The utility model relates to drying treatment equipment, in particular to drying treatment equipment for cordyceps militaris processing. Comprising a box body, a box door, supporting frames, a refrigerating mechanism, a heat insulation layer, a movable plate, an electric guide rail, a heating plate, a temperature sensor, a vacuum gauge, a control panel, an air valve, a first air pipe and a second air pipe, the box door is arranged on the front side of the box body, the supporting frames distributed in a bilateral symmetry mode are arranged in the box body, the refrigerating mechanism is arranged on the left side in the box body, and the heat insulation layer is arranged on the left side in the middle in the box body; an electric guide rail is arranged on the right side of the middle in the box body, a movable plate is connected to a movable piece of the electric guide rail, and the movable plate and the heat insulation layer jointly act to form a sealing face. Due to the design of the electric guide rail and the movable plate, the heating device and the refrigerating device can be separated through the heat insulation layer, the movable plate can be adjusted through the electric guide rail so that the heat insulation layer and the movable plate can be separated in the heating process, and therefore the heating efficiency is improved.

The invention discloses a composition for regulating overall metabolic balance, inhibiting cancer cell growth and resisting tumors. The composition comprises the following raw materials: lucid ganoderma, crocodile peptide, astragalus membranaceus, anoectochilus formosanus, ginseng, turmeric, clove, poria cocos, golden camellia, glutathione-rich yeast, cordyceps militaris, endothelium corneum gigeriae galli, peach kernels, compound probiotics and cardamine violifolia. According to the invention, the modern medical science concept and the theory of'caking caused by blood stasis and qi stagnation 'in the traditional Chinese medicine are fused, the raw materials have a synergistic effect, and mitochondria is protected from being damaged and mutated through the ways of increasing the blood oxygen content, resisting inflammation, improving the metabolic function, promoting blood circulation to remove blood stasis and the like; by means of supplementing composite probiotics and the like, intestinal flora is conditioned, immunity is enhanced, finally, the purposes of softening hardness to dissipate stagnation, adjusting overall metabolic balance, inhibiting cancer cell growth, resisting tumors and relieving tumor treatment side effects are achieved, and the application prospect is wide.

The invention relates to a traditional Chinese medicine preparation for treating gastritis and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation comprises the following raw materials in parts by weight: 40-50 parts of a traditional Chinese medicine composition, 10-15 parts of a sustained release agent, 25-32 parts of a filling agent and 3-8 parts of a flavoring agent, the slow release agent is modified carboxymethyl konjac glucomannan; the filling agent is cordyceps militaris polysaccharide and lactose; the flavoring agent is aspartame or sucralose. The sustained release agent is neohesperidin dihydrochalcone modified carboxymethyl konjac glucomannan, neohesperidin dihydrochalcone has the effect of inhibiting gastric acid secretion, and neohesperidin dihydrochalcone and the traditional Chinese medicine ingredient cuttlebone can synergistically play a role in preparing acid and jointly play a role in protecting gastric mucosa. Meanwhile, the cordyceps militaris polysaccharide has polysaccharide generality of thickening and stable film forming, and forms a compact network structure together with the modified carboxymethyl konjac glucomannan, and the obtained traditional Chinese medicine preparation has a good slow release effect.

The invention relates to a method for rapidly detecting adenosine in artificial cordyceps sinensis mycelium powder and application, and belongs to the technical field of medicine component extraction and detection. The cordyceps sinensis mycelium powder is gliocladium roseum strain powder separated from cordyceps sinensis, and the rapid detection method for adenosine in the artificial cordyceps sinensis mycelium powder comprises the following steps: (a) taking about 0.25 g of a sample, and adding 50 ml of 20% ethanol; (b) heating and refluxing at 100 DEG C for 1 hour; (c) performing microfiltration to obtain a test solution; and (d) injecting 5 [mu] l of the test solution into high performance liquid chromatography, separating by using an octadecylsilane chemically bonded silica chromatographic column and 7% acetonitrile as a mobile phase, and inspecting under the wavelength of a 260nm ultraviolet lamp. The method can be used for rapidly detecting the adenosine content in the artificial cordyceps sinensis mycelium powder.

The invention relates to a medicinal and edible compound extract for improving myelosuppression of a tumor patient after chemotherapy, and a preparation method and application of the medicinal and edible compound extract. The compound extract is extracted from a composition at least comprising the following raw material medicines in parts by weight: 0.9-10 parts of tricholoma matsutake, 0.9-10 parts of mulberry and 0.5-10 parts of rhizoma polygonati. The raw material medicine composition further comprises the following raw material medicines in parts by weight: 0.7-10 parts of longan, 0.5-10 parts of pericarpium citri reticulatae, 0.5-10 parts of scorched hawthorn fruit, 0.5-10 parts of fructus amomi, 1.1-10 parts of cordyceps sinensis rice flour and 2.5-15 parts of rice peptide. The selected raw material medicines are all medicinal and edible components, do not cause adverse effects on liver and kidney functions and gastrointestinal tracts of eaters, and are high in safety and high in patient acceptance degree. Effect verification results show that the mulberry compound extract has an improvement effect on the side effect of bone marrow suppression of tumor patients, especially in the early stage, no related adverse reaction is found, and a safe and effective treatment choice is provided for bone marrow suppression.

The application discloses a kind of composition of adjusting overall metabolic balance, inhibiting cancer cell growth, antitumor, raw material includes ganoderma lucidum, crocodile peptide, astragalus, polypodium pinnatum, ginseng, turmeric, clove, poria cocos, camellia sinensis, rich glutathione yeast, cordyceps militaris, gizzard gold, peach kernel, compound probiotics, brassica campestris l.var.rapa.The application fuses modern medical scientific concept and traditional Chinese medicine "blood stasis and stagnation and cause mass" theory, raw material synergistic effect, by improving blood oxygen content, anti-inflammatory, improve metabolic function, blood circulation and other ways, realize protection mitochondria from damage, anti-mutation;And through the way such as supplementing compound probiotics, regulate intestinal flora, enhance immunity, finally realize soft and hard knot, adjust overall metabolic balance, inhibit cancer cell growth, antitumor, relieve tumor treatment side effect, application prospect is wide.

The invention discloses a traditional Chinese medicine composition for treating middle and advanced stage tumors. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 9-11 parts of ganoderma lucidum slices, 1-3 parts of radix angelicae sinensis, 1-3 parts of cordyceps militaris, 5-7 parts of poria cocos, 1-3 parts of fructus lycii, 2-4 parts of radix astragali, 5-7 parts of polyporus umbellatus, 3-5 parts of ginseng slices and 3-5 parts of exocarpium citri grandis. The traditional Chinese medicine composition has the effects of benefiting qi and nourishing blood, tonifying kidney and spleen, and supporting healthy energy. The traditional Chinese medicine is used for treating qi and blood deficiency syndromes caused by middle and advanced tumors, wherein the syndromes comprise mental exhaustion, limb weakness, body emaciation, pale complexion, inappetence and the like. The traditional Chinese medicine composition can also be used for relieving toxic and side effects after radiotherapy and chemotherapy and early treatment of cancers. The invention further discloses a method for preparing the traditional Chinese medicine composition, the dosage form advantage is remarkable, the preparation process is stable and controllable, and the method is suitable for industrial production.