1019 results about "Chinese Medicinal Formulation" patented technology

The invention provides an online quality detection method of a nerve-soothing and brain-nourishing liquid based on multispectral fusion, and aims at solving the bottleneck problems of long offline time consumption, weak multi-index detection capability, poor dynamic adaptability and the like in the traditional detection technology, and realizing intelligent quality control of the whole process of the production technology. The device integrates an ultraviolet-visible spectrum module, a near-infrared spectrum module and a fluorescence spectrum module, constructs a multi-scale residual convolutional network to extract near-infrared spectrum characteristics, analyzes a fluorescence excitation-emission matrix through bidirectional LSTM, and cooperates with dynamic baseline correction of an ultraviolet spectrum, so that the icariin content detection precision is improved by 40% compared with that of a traditional HPLC method, the heavy metal residue detection lower limit reaches 0.05 ppm, and the detection accuracy is greatly improved. And an innovative solution is provided for intelligent production of traditional Chinese medicine preparations.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine preparation for treating Parkinson's disease and a preparation method thereof. The traditional Chinese medicine preparation for treating Parkinson's disease comprises the following raw materials in parts by weight: 20-30 parts of bischofia polycarpa, 17-25 parts of eucommia ulmoides, 12-16 parts of artemisia sphaerocephala, 10-15 parts of lycopodium clavatum, 8-13 parts of elm leaves, 7-14 parts of pericarpium citri reticulatae, 5-10 parts of semen cuscutae and 2-7 parts of liquorice. In the formula, monarch, minister, assistant and guide are reasonably matched, the curative effect is exact, and the effects of regulating qi and blood, nourishing liver, warming kidney, activating blood and dissipating blood stasis are achieved. The compound can effectively improve core symptoms of Parkinson's disease and delay disease progression, is expected to be further developed into clinical drugs for treatment of Parkinson's disease, and provides an innovative scheme for traditional Chinese medicine treatment of neurodegenerative diseases.

The invention relates to the technical field of quality detection of traditional Chinese medicine preparations, in particular to a quality detection method of rhizoma pinelliae, rhizoma atractylodis macrocephalae and rhizoma gastrodiae granules, and the rhizoma pinelliae, rhizoma atractylodis macrocephalae and rhizoma gastrodiae granules established by the invention are proved to be safe and effective through quality inspection. The rhizoma pinelliae, rhizoma atractylodis macrocephalae and rhizoma gastrodiae granules not only keep the effects of eliminating dampness, reducing phlegm, calming the liver and calming endogenous wind in an original prescription, but also overcome the defects that a decoction is temporarily decocted, time-consuming and energy-consuming, is easy to mildew and deteriorate after being placed for a long time and the like, are smaller in dosage and more convenient to take, carry, store and transport, and greatly reduce the labor intensity and shorten the labor time, so that the production cost of the rhizoma pinelliae, rhizoma atractylodis macrocephalae and rhizoma gastrodiae granules is reduced. And the burden of people is greatly relieved, the market vacancy is filled, the economic benefit is considerable, and obvious advantages are achieved.

The invention discloses a traditional Chinese medicine composition, a preparation method of the traditional Chinese medicine composition, a traditional Chinese medicine preparation and application of the traditional Chinese medicine preparation, and relates to the technical field of medicine production. 9 to 12 parts of ginkgo leaf; 9-30 parts of radix astragali; 9 to 15 parts of hypericum perforatum; 6 to 15 parts of jujube; 3-9 parts of red ginseng; 9-15 parts of semen ziziphi spinosae; and 3-6 parts of valerian. All the medicines in the traditional Chinese medicine composition have a synergistic effect, the curative effect is enhanced, and the depressive symptom is improved together.

The invention provides a traditional Chinese medicine granule fluidized bed drying uniformity online monitoring and improving method and device, relates to the field of traditional Chinese medicine preparation production and online quality control, and solves the technical problem of uniformity judgment deviation caused by single-bed data isolated monitoring. The method comprises the following steps: inputting secondary bed outlet particle spectral data into a spectral model to obtain a secondary bed predicted water content M2, and integrating temperature data of each bed, process parameters and the secondary bed predicted water content M2 to construct a database. And an input vector set is generated after preprocessing. And inputting the input vector set into a principal component analysis model, performing PCA dimension reduction on the input vector set, extracting main components, and inputting the main components into a Hotelling T-party monitoring model. And calculating a control limit based on multiple batches of historical qualified data, comparing the T-party statistical magnitude with the control limit to judge a drying uniformity grade, and outputting a corresponding regulation and control strategy according to the drying uniformity grade. The method is used in the production and on-line quality control process of the traditional Chinese medicine preparation.

The invention discloses fermentation liquor of a traditional Chinese medicine preparation, a preparation method of the fermentation liquor and application of the fermentation liquor in the aspects of losing weight, lowering lipid and / or relieving liver injury. The traditional Chinese medicine preparation is prepared from the following components in parts by weight: 3 to 6 parts of mulberries, 3 to 6 parts of raspberries, 3 to 6 parts of fructus corni, 12 to 20 parts of fructus lycii, 15 to 25 parts of rhizoma polygonati, 15 to 25 parts of fructus crataegi and 2 to 5 parts of semen cassiae. The traditional Chinese medicine preparation is prepared by extracting, sterilizing, cooling, inoculating a leavening agent and fermenting. The mulberry, the raspberry and the dogwood which are medicinal and edible materials are used for replacing fleece-flower root, the original formula of the lipid-lowering drug is combined, the fermentation liquor prepared after fermentation can effectively retain the obesity adjusting effect of the classic formula of the lipid-lowering drug, meanwhile, the biological activity of the lipid-lowering drug is remarkably improved through the optimized compatibility and the probiotic fermentation technology, and the lipid-lowering drug has a good application prospect. A safe and efficient innovative scheme is provided for functional food to intervene in obesity / overweight.

This invention proposes an online quality detection method for An Shen Bu Nao Liquid based on multispectral fusion. Addressing the bottlenecks of traditional detection techniques, such as long offline processing time, weak multi-index detection capabilities, and poor dynamic adaptability, this method achieves intelligent quality control throughout the entire production process. The device integrates ultraviolet-visible spectroscopy, near-infrared spectroscopy, and fluorescence spectroscopy modules. It constructs a multi-scale residual convolutional network to extract ultraviolet-visible spectral features, uses a two-way LSTM to analyze the fluorescence excitation-emission matrix, and employs dynamic baseline correction of the ultraviolet spectrum. This improves the detection accuracy of icariin content by 40% compared to traditional HPLC methods, and achieves a heavy metal residue detection limit of 0.05 ppm, providing an innovative solution for the intelligent production of traditional Chinese medicine preparations.

The invention provides an efficient microbial fermentation device for traditional Chinese medicine preparation processing, and relates to the technical field of traditional Chinese medicine preparation biological fermentation, the efficient microbial fermentation device comprises a tank body and an inlet, the tank body is provided with a rotating assembly, the rotating assembly comprises a first motor and a sealing sleeve, the inner side of the tank body is provided with a stirring assembly, and the stirring assembly comprises a connecting shaft and a rotating pipe; according to the efficient microbial fermentation device for processing the traditional Chinese medicine preparation, when the first motor is damaged, the second motor drives the connecting shaft and the rotating pipe to rotate on the inner side of the tank body, and the connecting shaft and the rotating pipe are driven to rotate through the second motor; therefore, normal stirring and temperature control work in the tank body is guaranteed, abnormal fermentation of microorganisms caused by the fact that stirring and temperature control cannot be conducted on the tank body in the maintenance period of the first motor is avoided, the processing quality of traditional Chinese medicine is guaranteed, fermentation safety of traditional Chinese medicine in the tank body is guaranteed, and the device is suitable for microbial fermentation processing of traditional Chinese medicine preparations.

The invention belongs to the technical field of medicine taste masking, and particularly relates to a traditional Chinese medicine taste-masking water-in-water Pickering emulsion, a microcapsule, a preparation method and application. A first polymer system aqueous solution in which a water-soluble bitter drug is dispersed and a second polymer system aqueous solution in which a particle stabilizer is dispersed are mixed and emulsified, so that the water-soluble bitter drug is embedded into an inner phase of a water-in-water emulsion, and the traditional Chinese medicine taste-masking water-in-water Pickering emulsion is prepared. The traditional Chinese medicine taste-masked water-in-water Pickering emulsion is dried and granulated, and the traditional Chinese medicine taste-masked microcapsule can be obtained. The traditional Chinese medicine taste-masking water-in-water Pickering emulsion and microcapsule provided by the invention have excellent taste-masking effect and good stability, effectively solve the problem of poor taste-masking effect of traditional Chinese medicine preparations, provide a new method for taste masking of extremely bitter traditional Chinese medicines, and have important significance for development and application of traditional Chinese medicine taste-masking preparations.

The invention discloses a traditional Chinese medicine preparation for treating multi-system atrophic upright hypotension and a preparation method. The traditional Chinese medicine preparation is prepared from the following raw materials: ginseng, astragalus membranaceus, antler, roasted ephedra, rehmannia, radix ophiopogonis, radix paeoniae alba, rhizoma cimicifugae and pericarpium citri reticulatae viride. The traditional Chinese medicine composition has the effects of tonifying qi, warming yang, nourishing blood and yin and ascending and descending qi function, and emphasizes the effect of ascending and descending qi function in blood pressure regulation by perfecting the etiology and pathogenesis of MSA erect hypotension; the pathogenesis of the MSA erect hypotension is mainly viscera asthenia and qi and blood ascending and descending disorder, so that the treatment effect is achieved by ascending yang and nourishing yin.

The invention belongs to the technical field of traditional Chinese medicine preparations, and relates to fingered citron-albizia flower compatible traditional Chinese medicine oral liquid for soothing nerves, helping sleep and resisting depression and a preparation method thereof. The oral liquid consists of medicinal materials such as fingered citron, albizia flower, fried jujube kernel, polygala tenuifolia, lily, angelica sinensis, ginseng, radix curcumae, platycladi seed, rhizoma acori graminei and poria cocos, and is supplemented with components such as honeysuckle, liquorice, medlar, honey, phaseolus calcaratus, salvia miltiorrhiza and lophatherum gracile. The preparation method comprises the following steps: stir-frying jujube kernels, soaking medicinal materials, performing double-stage water decoction extraction, performing vacuum concentration, blending honey, performing ultrasonic treatment, performing pasteurization, filling and the like. Animal experiment results show that the traditional Chinese medicine composition is superior to a plurality of contrast groups in the aspects of improving sleep latency, prolonging sleep time, reducing depression-like behaviors, improving sweet water preference and the like, and shows good compatibility synergy and behavior regulation potential.

The embodiment of the invention provides a traditional Chinese medicine preparation for improving lung qi and yin deficiency constitution and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following raw materials: 1-3 parts of American ginseng, 2-15 parts of Chinese yam, 1.5-9 parts of codonopsis pilosula, 1-6 parts of dendrobium officinale, 1.5-9 parts of rhizoma polygonati, 0.5-2 parts of schisandra chinensis, 2-6 parts of lily, 1-3 parts of pericarpium citri reticulatae, 1-2 parts of liquorice, 1-5 parts of folium mori, 1-3 parts of donkey-hide gelatin, 1-3 parts of mint, 1-6 parts of angelica sinensis and 2-9 parts of coix seeds. Therefore, the traditional Chinese medicine composition has the functions of tonifying qi and yin, clearing heat and moistening lung, replenishing blood and promoting salivation, and relieving cough and reducing sputum, and can be widely applied to chronic cough, various pneumonia, pulmonary tuberculosis, chronic obstructive pulmonary disease, lung malignant tumor, asthma remission period of asthma, respiratory failure and other syndrome-differentiated lung qi and yin deficiency patients.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine spray for treating rhinitis and a preparation method thereof.The traditional Chinese medicine spray is prepared from flos magnoliae liliflorae, fructus xanthii, herba ephedrae, fructus forsythiae, flos lonicerae, radix angelicae, herba asari, menthol, herba centipedae and herba menthae. Refining to obtain a fluid extract; and mixing the fluid extract with a penetration enhancer consisting of aminoketone and menthol, a sodium hyaluronate mucous membrane repairing agent, a pH regulator, an isoosmotic adjusting agent and a preservative to prepare spray liquid medicine, and finally performing sterile filtration and filling. Through efficient extraction and synergism of composite auxiliary materials, the permeability and bioavailability of the medicine are remarkably improved, and the symptoms such as nasal obstruction and running nose can be quickly relieved; meanwhile, the anti-inflammatory function and the function of actively repairing the damaged nasal mucosa are achieved, and the recurrence rate is reduced from the source; the pH and osmotic pressure of the preparation are precisely adjusted, the use is comfortable, and the quality is stable and controllable.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine compound preparation for preventing and treating sepsis based on intestinal treatment and gasification regulation and a preparation method and application of the traditional Chinese medicine compound preparation. The composition is prepared from the following medicinal materials in parts by weight: 3 to 10 parts of rheum officinale, 5 to 10 parts of fructus aurantii, 5 to 10 parts of radix aucklandiae, 10 to 15 parts of fructus gardeniae, 10 to 15 parts of dandelion, 10 to 15 parts of fructus forsythiae, 10 to 15 parts of herba artemisiae scopariae, 10 to 15 parts of rhizoma atractylodis, 10 to 15 parts of poria cocos, 10 to 15 parts of radix paeoniae rubra, 10 to 15 parts of radix salviae miltiorrhizae, 15 to 20 parts of astragalus membranaceus, 10 to 15 parts of rhizoma anemarrhenae, 10 to 15 parts of fructus cannabis, 10 to 15 parts of semen pruni and 3 to 6 parts of raw liquorice. The traditional Chinese medicine compound provided by the invention considers the treatment rules of relaxing bowels, purging heat, promoting qi circulation, removing stagnation, detoxifying, dispersing blood stasis, reinforcing qi, nourishing yin and the like, and also considers the effects of relaxing bowels, regulating qi and supporting healthy qi, various diseases of sepsis patients can be remarkably improved through the synergistic effect of the medicines in the formula, and the traditional Chinese medicine compound especially has an obvious curative effect on gastrointestinal dysfunction. A novel traditional Chinese medicine treatment thought is provided for clinical treatment of sepsis diseases.

The invention discloses a traditional Chinese medicine composition for treating or improving hypoovarian reserve function and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by weight: angelica sinensis, parched white paeony root, parasitic loranthus, dodder, roasted rhizoma atractylodis macrocephalae, ligusticum wallichii, herba lycopi, albizia flower and honey-fried licorice root. And after ovulation, morinda officinalis and glossy privet fruit are added. The formula provided by the invention complies with the natural law of human bodies, and according to the growth of qi and blood, yin and yang, nourishing blood, activating blood and tonifying kidney, yin and yang are tonified without stagnation, and blood stasis is removed without hurting healthy qi; meanwhile, the traditional Chinese medicine is used for strengthening the root of acquired days, quieting the main internal organs, combining dynamic and static, regulating qi-blood yin-yang balance and taking the balance as a period. The invention further provides application of the composition or the traditional Chinese medicine extract or the traditional Chinese medicine preparation in preparation of a medicine for treating or improving ovarian reserve hypofunction.

The invention provides a traditional Chinese medicine preparation for treating allergic rhinitis and a preparation method thereof, and relates to the technical field of traditional Chinese medicine pharmacy, the traditional Chinese medicine preparation is prepared from radix asteris, schizonepeta spike, cynanchum paniculatum, perillaseed, spina gleditsiae, cottonrose hibiscus leaf, magnolia flower, semen brassicae, cortex lycii radicis, dendrobe, oroxylum indicum and rhodomyrtus tomentosa; an in-vitro experiment shows that the traditional Chinese medicine preparation can remarkably inhibit the activity of hyaluronidase, also can inhibit the release of beta-HEX in an RBL-2H3 cell degranulation model, reduces the HIS level in a cell supernatant, and effectively improves the morphological abnormality caused by degranulation of RBL-2H3 cells; in-vivo experiments show that the traditional Chinese medicine preparation can significantly reduce behavioral scores of mice suffering from allergic rhinitis, inhibit expression of inflammatory factors TNF-alpha, serum Ig E and OVE-sIg E levels and HA concentration, reduce histopathologic changes caused by allergic rhinitis, effectively repair immune injuries of nasal mucosa of the mice and improve the curative effect of the mice. And a safe and effective new strategy is provided for the treatment of allergic rhinitis.

The invention provides a preparation method and a quality detection method of a nutgall standard decoction. The preparation method comprises the following steps: (1) mixing a nutgall medicinal material with water of which the mass is 8-12 times that of the nutgall medicinal material, and sequentially performing first soaking, first decoction and solid-liquid separation to obtain first filtrate and first medicine residues; (2) mixing the first medicine residue with water which is 6-10 times of the mass of the nutgall medicinal material, performing secondary decoction, and performing solid-liquid separation after secondary decoction to obtain a second filtrate; and (3) combining the first filtrate and the second filtrate to obtain a nutgall filtrate, namely the standard nutgall decoction. The method can solve the problem of lack of a preparation method of a standard gallnut decoction in the prior art, and is suitable for the field of traditional Chinese medicine preparations.

The invention belongs to the field of traditional Chinese medicine preparations, and provides a pure traditional Chinese medicine preparation for treating depression and a preparation method of the pure traditional Chinese medicine preparation. The preparation method comprises the following steps: S1, weighing raw materials according to a formula, putting the raw materials into a clean container, adding water which is 8-12 times of the total weight of the raw materials, and soaking at room temperature for 1-2 hours; s2, transferring the soaked raw materials and liquid medicine into a decoction container, boiling with strong fire, then turning into slow fire, and decocting for 1.5-2.5 hours in a slightly boiling state; according to the pure traditional Chinese medicine preparation disclosed by the invention, through reasonable compatibility of various traditional Chinese medicinal materials, all the components have a synergistic effect, and the effects of soothing liver and regulating qi, strengthening spleen and harmonizing stomach, nourishing heart and tranquilizing mind, promoting blood circulation to remove blood stasis, reducing phlegm and clearing damp are jointly achieved; the pure traditional Chinese medicine preparation can effectively improve the symptoms of low mood, restless mood, insomnia and dreaminess, inappetence and hypodynamia of depression patients, and clinical practice verifies that the pure traditional Chinese medicine preparation prepared by the invention has a remarkable effect in the aspect of treating depression compared with existing conventional anti-depression western medicines.

The invention relates to the field of quality detection of traditional Chinese medicine preparations and specifically provides a method for constructing a characteristic spectrum of nardostachys radix and a preparation thereof and a quality detection method. In the characteristic spectrum construction method, chromatographic conditions include: using acetonitrile and an aqueous solution containing formic acid as mobile phases for gradient elution, the gradient elution program includes: 0-5 min-40 min-50 min, and the volume percentage of acetonitrile in the mobile phase is: 10%-10%-35%-50%. Under the specific elution program, 9 common characteristic peaks are obtained, and good separation of the common characteristic peaks is achieved. The obtained characteristic spectrum has a stable baseline, good characteristic peak shape, good separation effect, and strong characteristic component specificity. The method provides a basis for quality detection and control of nardostachys radix and a preparation thereof, achieves characterization of the overall components of nardostachys radix and a preparation thereof, and has stable reproducibility.

The invention relates to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating atopic dermatitis. The traditional Chinese medicine composition contains cynanchum paniculatum, tripterygium wilfordii, bletilla striata, cuttlebone, duckweed, mint, radix sophorae flavescentis, golden cypress, moutan bark and liquorice. In addition, the invention further provides a traditional Chinese medicine preparation for treating atopic dermatitis and a preparation method and application of the traditional Chinese medicine preparation. The traditional Chinese medicine composition has the effects of dispelling wind, relieving itching, astringing to stop bleeding, clearing heat, drying dampness, detoxifying and dredging collaterals, and has no toxic or side effect.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to an innovative formula and a preparation method of a traditional Chinese medicine preparation for relieving cough and asthma, and the traditional Chinese medicine preparation comprises the following medicinal materials in parts by weight: 10-20 parts of flos farfarae, 10-20 parts of radix asteris, 5-15 parts of ephedra, 5-15 parts of almond, 5-15 parts of scutellaria baicalensis, 5-15 parts of white mulberry root-bark, 5-15 parts of radix stemonae and 3-10 parts of liquorice. Through reasonable compatibility of various traditional Chinese medicines, the traditional Chinese medicine composition acts on the respiratory system in a multi-target manner, can moisten the lung to arrest cough, can release the lung to relieve asthma, can clear heat and reduce phlegm, and has a good treatment effect on cough and asthma caused by various reasons. Animal experiments and clinical preliminary verifications prove that compared with a traditional Chinese medicine preparation for relieving cough and asthma, the preparation disclosed by the invention can more remarkably prolong the cough latency period, reduce the cough frequency, relieve the asthma symptom and improve the lung function, and the links such as reduced pressure concentration and preparation forming in the preparation process are all carried out under strict condition control, so that the traditional Chinese medicine preparation is free of toxic and side effects. The loss and degradation of effective components are reduced, and the stability and consistency of the product quality are ensured.

The invention relates to a traditional Chinese medicine preparation for treating mild and moderate spleen and kidney deficiency and phlegm and blood stasis type Alzheimer's disease sleep disorder and a preparation method of the traditional Chinese medicine preparation, and belongs to the field of traditional Chinese medicine treatment preparations for Alzheimer's disease. The traditional Chinese medicine preparation is prepared from the following traditional Chinese medicine raw materials: rhizoma acori graminei, borneol, poria with hostwood, rhizoma atractylodis macrocephalae, codonopsis pilosula, radix astragali preparata, fructus evodiae, ramulus euonymi, polygala tenuifolia, lily, caulis polygoni multiflori and fossil fragments. The traditional Chinese medicine composition is used for treating mild and moderate spleen and kidney deficiency and phlegm and blood stasis type Alzheimer's disease sleep disorder, and has a good treatment effect. Sleep of patients with mild and moderate spleen and kidney deficiency and phlegm and blood stasis type Alzheimer's disease sleep disorder is evaluated through the intelligent bracelet, sleep condition quantitative monitoring is conducted, traditional Chinese medicine acupoint application treatment is conducted through a traditional Chinese medicine characteristic therapy method, the sleep quality and structure changes of the patients are evaluated, the treatment effect of traditional Chinese medicine acupoint application on the patients is researched, and the clinical application prospect is wide. Therefore, a clinical basis is provided for objective evaluation and standardized treatment of the sleep disorder, and the method has very important clinical significance for improving the life quality of a patient and evaluating prognosis.

The invention relates to the technical field of plant environment control, and particularly discloses a traditional Chinese medicine plant cross contamination prevention system and method based on multi-source data fusion and AI dynamic regulation, and the system is composed of a sensing layer, a data processing layer, a decision-making layer and an execution layer. BIM space information and MES working condition data are fused, and a digital twinborn and pollution risk thermodynamic diagram of the factory building is constructed; lSTM prediction and reinforcement learning are utilized to generate a cooperative control strategy of the air supply and exhaust rate, the air valve opening degree and the adjustable air opening angle of each area, airflow is guided to be discharged in the direction from a pollution source to an air outlet, early warning and active suppression of dust and solvent gas cross contamination are achieved, the cleanliness reaches the standard, energy is saved, consumption is reduced, and the method is suitable for large-scale popularization and application. The method is suitable for traditional Chinese medicine preparation workshops and similar clean environments.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a pharmaceutical composition for treating benign prostatic hyperplasia and a preparation method thereof. The composition is prepared from the following medicinal materials in parts by weight: 6 to 8 parts of radix aconiti lateralis preparata, 3 to 5 parts of cortex cinnamomi, 10 to 15 parts of fructus alpiniae oxyphyllae, 10 to 15 parts of fructus psoraleae, 5 to 10 parts of semen myristicae, 5 to 10 parts of ground beeltle, 8 to 12 parts of spina gleditsiae, 10 to 15 parts of radix angelicae sinensis, 8 to 12 parts of radix linderae, 15 to 20 parts of radix rehmanniae praeparata, 10 to 15 parts of fructus corni, 8 to 12 parts of rhizoma anemarrhenae, 15 to 20 parts of radix scrophulariae, 8 to 12 parts of rhizoma alismatis, 5 to 10 parts of radix stephaniae tetrandrae and 10 to 15 parts of radix cyathulae. The invention provides the self-prepared medicine composition for treating the prostatic hyperplasia, the diseases of patients with the prostatic hyperplasia are remarkably improved through the synergistic effect of all the medicines in the composition, and a new traditional Chinese medicine treatment thought is provided for clinical treatment of the BPH disease. According to the traditional Chinese medicine composition, medicine pairs are increased or decreased on the basis of referring to a traditional Chinese medicine classic treatment compound, the unique traditional Chinese medicine composition is finally formed, and all the medicine pairs in the formula cooperate with one another and are indispensable.

The invention discloses a preparation method and application of a traditional Chinese medicine compound preparation for treating acne, and relates to the technical field of traditional Chinese medicine preparations. Comprising 12 kinds of coptis chinensis, rheum officinale, scutellaria baicalensis, radix sophorae flavescentis, honeysuckle, dandelion, selfheal, rhizoma anemarrhenae, salvia miltiorrhiza, clove, pepper and pomegranate rind. The traditional Chinese medicine composition comprises the following components in parts by weight: 1-2 parts of coptis chinensis, 3-5 parts of rheum officinale, 1-3 parts of scutellaria baicalensis, 1-3 parts of radix sophorae flavescentis, 3-5 parts of honeysuckle, 3-5 parts of dandelion, 3-5 parts of selfheal, 2-4 parts of rhizoma anemarrhenae, 3-5 parts of salvia miltiorrhiza, 0.5-1.5 parts of clove, 1-2 parts of pepper and 1-3 parts of pomegranate rind. The traditional Chinese medicine compound preparation has the effects of clearing away heat and toxic materials, diminishing swelling and removing stasis, removing acnes and inhibiting bacteria. The traditional Chinese medicine composition for treating acne has the advantages of being safe, good in effect and convenient to use when being used for treating acne.

The invention discloses a production and preparation method of palatability-enhanced compound double-flower oral liquid, and relates to the technical field of traditional Chinese medicine preparations. The production and preparation method of the oral liquid comprises the following steps: pretreatment of medicinal materials: taking herba andrographitis, honeysuckle, radix isatidis, fructus forsythiae, honey and dark plum, washing, denucleating and slicing the dark plum (the honey is in a liquid state and does not need to be pretreated), ultrasonic extraction, integrated purification, filtrate collection, dynamic taste modification, sterilization and filling; the method has the advantages that bitter components are accurately neutralized by an innovative gradient inclusion process, qualitative leap of a bitter masking effect is realized, sensory evaluation is verified according to international standards, children acceptance score reaches an excellent level (full score of 10 scores), the core problem that children refer to take medicines due to bitter taste is thoroughly solved, the treatment compliance of patients is remarkably improved, and the treatment cost is reduced. The continuity of medication is ensured, a breakthrough solution is provided for the field of medication for children, and meanwhile, a technical normal form is provided for improvement of medicines similar to bitter taste.

The present application belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating recurrent oral ulcer, a traditional Chinese medicine preparation and a preparation method. The traditional Chinese medicine composition for treating recurrent oral ulcer has the effects of supporting healthy qi, promoting tissue regeneration and clearing heat and detoxifying, is scientific and reasonable in prescription, and simple in preparation process. When used as a medicine for treating recurrent oral ulcer, the traditional Chinese medicine composition has the excellent characteristics of remarkable curative effect, short treatment course, low recurrence after recovery, small toxic and side effects, and can effectively avoid the adverse reactions caused by western medicines. The traditional Chinese medicine composition for treating recurrent oral ulcer is accurate and complete in syndrome differentiation, has the synergistic effect of components, treats symptoms and root causes at the same time, has good treatment effect and low recurrence rate, and is helpful to popularization and application in production practice.

The invention discloses a radix astragali, rhizoma polygonati and ligustrum lucidum ait traditional Chinese medicine preparation for treating myelosuppression as well as a preparation method and a detection method thereof. The preparation is prepared from 50-150 parts of radix astragali, 50-150 parts of wine-processed rhizoma polygonati, 25-75 parts of wine-processed ligustrum lucidum ait, 50-150 parts of blanched rhizoma drynariae, 50-150 parts of radix trichosanthis and 25-75 parts of herba epimedii. The optimal extraction process and refining process are screened out based on effective components and pharmacological activity through a large number of tests, and the optimal preparation process of the Shuanghuangliangwhitening oral liquid and other traditional Chinese medicine preparations is obtained through stability investigation and verification. According to the invention, a thin layer chromatography is adopted, the four medicinal materials of astragalus membranaceus, glossy privet fruit, rhizoma drynariae and herba epimedii are respectively subjected to thin layer chromatography research, and methodology research shows that the method is stable and feasible. The invention establishes a content determination method for astragaloside, calycosin-7-glucoside, specnuezhenide and icariin, establishes a quality standard, and has important significance for ensuring the clinical curative effect and safety of astragaloside, calycosin-7-glucoside, specnuezhenide and icariin.

The invention relates to the technical field of traditional Chinese medicine preparation production, and discloses a continuous traditional Chinese medicine extraction and concentration device which comprises a waste heat tank, a heating tank and a concentration tank which are sequentially connected along a processing procedure, a waste heat collecting box is installed on a gas outlet of the heating tank, a second liquid pump is arranged at the output end of the heating tank and connected with the input end of the concentration tank through a pipeline, and the waste heat collecting box preheats original liquid medicine in a waste heat tank through waste heat generated by high-temperature gas; a condensation assembly, a second pipeline fan and a hot drying assembly are sequentially connected between the air inlet and the air outlet in the concentration tank. Continuous production is realized through process separation of the waste heat tank, the heating tank and the concentration tank, and continuous input of original liquid medicine is realized; the condensation assembly is connected between the air outlet and the air inlet of the concentration tank, and the pipeline fan and the hot drying assembly jointly form a closed space which does not interact with outside air, so that the concentration stability is higher, and the concentration efficiency and the concentration precision are higher.

The invention provides a traditional Chinese medicine preparation quality detection method and system based on multi-dimensional data analysis, and belongs to the technical field of traditional Chinese medicine preparation quality detection. The method comprises the following steps: acquiring mass spectrum data and nuclear magnetic resonance data of various active components in a preparation to generate a multi-dimensional chemical characteristic data set; synchronously collecting corresponding data of the medicinal raw materials, and constructing a process and environment association database; constructing a chemical and process coupling analysis model; and monitoring the production process in real time to obtain the dynamic chemical fingerprint spectrum. By constructing a full-component chemical map and associating the full-component chemical map with process and environmental parameters and combining clinical curative effect data to establish a drug effect and component response curved surface model, the limitation that only a few index components are concerned in traditional detection is broken through, so that a detection result can accurately reflect the multi-target and overall regulation characteristics of the traditional Chinese medicine preparation, and the detection accuracy is improved. The problem that the components are qualified but the curative effect is poor due to single detection dimension is avoided, and the relevance between quality detection and the clinical curative effect is remarkably improved.