715 results about "Chinese Medicinal Formulation" patented technology

The invention provides a traditional Chinese medicine granule fluidized bed drying uniformity online monitoring and improving method and device, relates to the field of traditional Chinese medicine preparation production and online quality control, and solves the technical problem of uniformity judgment deviation caused by single-bed data isolated monitoring. The method comprises the following steps: inputting secondary bed outlet particle spectral data into a spectral model to obtain a secondary bed predicted water content M2, and integrating temperature data of each bed, process parameters and the secondary bed predicted water content M2 to construct a database. And an input vector set is generated after preprocessing. And inputting the input vector set into a principal component analysis model, performing PCA dimension reduction on the input vector set, extracting main components, and inputting the main components into a Hotelling T-party monitoring model. And calculating a control limit based on multiple batches of historical qualified data, comparing the T-party statistical magnitude with the control limit to judge a drying uniformity grade, and outputting a corresponding regulation and control strategy according to the drying uniformity grade. The method is used in the production and on-line quality control process of the traditional Chinese medicine preparation.

This invention proposes an online quality detection method for An Shen Bu Nao Liquid based on multispectral fusion. Addressing the bottlenecks of traditional detection techniques, such as long offline processing time, weak multi-index detection capabilities, and poor dynamic adaptability, this method achieves intelligent quality control throughout the entire production process. The device integrates ultraviolet-visible spectroscopy, near-infrared spectroscopy, and fluorescence spectroscopy modules. It constructs a multi-scale residual convolutional network to extract ultraviolet-visible spectral features, uses a two-way LSTM to analyze the fluorescence excitation-emission matrix, and employs dynamic baseline correction of the ultraviolet spectrum. This improves the detection accuracy of icariin content by 40% compared to traditional HPLC methods, and achieves a heavy metal residue detection limit of 0.05 ppm, providing an innovative solution for the intelligent production of traditional Chinese medicine preparations.

The embodiment of the invention provides a traditional Chinese medicine preparation for improving lung qi and yin deficiency constitution and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following raw materials: 1-3 parts of American ginseng, 2-15 parts of Chinese yam, 1.5-9 parts of codonopsis pilosula, 1-6 parts of dendrobium officinale, 1.5-9 parts of rhizoma polygonati, 0.5-2 parts of schisandra chinensis, 2-6 parts of lily, 1-3 parts of pericarpium citri reticulatae, 1-2 parts of liquorice, 1-5 parts of folium mori, 1-3 parts of donkey-hide gelatin, 1-3 parts of mint, 1-6 parts of angelica sinensis and 2-9 parts of coix seeds. Therefore, the traditional Chinese medicine composition has the functions of tonifying qi and yin, clearing heat and moistening lung, replenishing blood and promoting salivation, and relieving cough and reducing sputum, and can be widely applied to chronic cough, various pneumonia, pulmonary tuberculosis, chronic obstructive pulmonary disease, lung malignant tumor, asthma remission period of asthma, respiratory failure and other syndrome-differentiated lung qi and yin deficiency patients.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine spray for treating rhinitis and a preparation method thereof.The traditional Chinese medicine spray is prepared from flos magnoliae liliflorae, fructus xanthii, herba ephedrae, fructus forsythiae, flos lonicerae, radix angelicae, herba asari, menthol, herba centipedae and herba menthae. Refining to obtain a fluid extract; and mixing the fluid extract with a penetration enhancer consisting of aminoketone and menthol, a sodium hyaluronate mucous membrane repairing agent, a pH regulator, an isoosmotic adjusting agent and a preservative to prepare spray liquid medicine, and finally performing sterile filtration and filling. Through efficient extraction and synergism of composite auxiliary materials, the permeability and bioavailability of the medicine are remarkably improved, and the symptoms such as nasal obstruction and running nose can be quickly relieved; meanwhile, the anti-inflammatory function and the function of actively repairing the damaged nasal mucosa are achieved, and the recurrence rate is reduced from the source; the pH and osmotic pressure of the preparation are precisely adjusted, the use is comfortable, and the quality is stable and controllable.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine compound preparation for preventing and treating sepsis based on intestinal treatment and gasification regulation and a preparation method and application of the traditional Chinese medicine compound preparation. The composition is prepared from the following medicinal materials in parts by weight: 3 to 10 parts of rheum officinale, 5 to 10 parts of fructus aurantii, 5 to 10 parts of radix aucklandiae, 10 to 15 parts of fructus gardeniae, 10 to 15 parts of dandelion, 10 to 15 parts of fructus forsythiae, 10 to 15 parts of herba artemisiae scopariae, 10 to 15 parts of rhizoma atractylodis, 10 to 15 parts of poria cocos, 10 to 15 parts of radix paeoniae rubra, 10 to 15 parts of radix salviae miltiorrhizae, 15 to 20 parts of astragalus membranaceus, 10 to 15 parts of rhizoma anemarrhenae, 10 to 15 parts of fructus cannabis, 10 to 15 parts of semen pruni and 3 to 6 parts of raw liquorice. The traditional Chinese medicine compound provided by the invention considers the treatment rules of relaxing bowels, purging heat, promoting qi circulation, removing stagnation, detoxifying, dispersing blood stasis, reinforcing qi, nourishing yin and the like, and also considers the effects of relaxing bowels, regulating qi and supporting healthy qi, various diseases of sepsis patients can be remarkably improved through the synergistic effect of the medicines in the formula, and the traditional Chinese medicine compound especially has an obvious curative effect on gastrointestinal dysfunction. A novel traditional Chinese medicine treatment thought is provided for clinical treatment of sepsis diseases.

The invention discloses a traditional Chinese medicine composition for treating or improving hypoovarian reserve function and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by weight: angelica sinensis, parched white paeony root, parasitic loranthus, dodder, roasted rhizoma atractylodis macrocephalae, ligusticum wallichii, herba lycopi, albizia flower and honey-fried licorice root. And after ovulation, morinda officinalis and glossy privet fruit are added. The formula provided by the invention complies with the natural law of human bodies, and according to the growth of qi and blood, yin and yang, nourishing blood, activating blood and tonifying kidney, yin and yang are tonified without stagnation, and blood stasis is removed without hurting healthy qi; meanwhile, the traditional Chinese medicine is used for strengthening the root of acquired days, quieting the main internal organs, combining dynamic and static, regulating qi-blood yin-yang balance and taking the balance as a period. The invention further provides application of the composition or the traditional Chinese medicine extract or the traditional Chinese medicine preparation in preparation of a medicine for treating or improving ovarian reserve hypofunction.

The invention provides a traditional Chinese medicine preparation for treating allergic rhinitis and a preparation method thereof, and relates to the technical field of traditional Chinese medicine pharmacy, the traditional Chinese medicine preparation is prepared from radix asteris, schizonepeta spike, cynanchum paniculatum, perillaseed, spina gleditsiae, cottonrose hibiscus leaf, magnolia flower, semen brassicae, cortex lycii radicis, dendrobe, oroxylum indicum and rhodomyrtus tomentosa; an in-vitro experiment shows that the traditional Chinese medicine preparation can remarkably inhibit the activity of hyaluronidase, also can inhibit the release of beta-HEX in an RBL-2H3 cell degranulation model, reduces the HIS level in a cell supernatant, and effectively improves the morphological abnormality caused by degranulation of RBL-2H3 cells; in-vivo experiments show that the traditional Chinese medicine preparation can significantly reduce behavioral scores of mice suffering from allergic rhinitis, inhibit expression of inflammatory factors TNF-alpha, serum Ig E and OVE-sIg E levels and HA concentration, reduce histopathologic changes caused by allergic rhinitis, effectively repair immune injuries of nasal mucosa of the mice and improve the curative effect of the mice. And a safe and effective new strategy is provided for the treatment of allergic rhinitis.

The invention relates to the technical field of plant environment control, and particularly discloses a traditional Chinese medicine plant cross contamination prevention system and method based on multi-source data fusion and AI dynamic regulation, and the system is composed of a sensing layer, a data processing layer, a decision-making layer and an execution layer. BIM space information and MES working condition data are fused, and a digital twinborn and pollution risk thermodynamic diagram of the factory building is constructed; lSTM prediction and reinforcement learning are utilized to generate a cooperative control strategy of the air supply and exhaust rate, the air valve opening degree and the adjustable air opening angle of each area, airflow is guided to be discharged in the direction from a pollution source to an air outlet, early warning and active suppression of dust and solvent gas cross contamination are achieved, the cleanliness reaches the standard, energy is saved, consumption is reduced, and the method is suitable for large-scale popularization and application. The method is suitable for traditional Chinese medicine preparation workshops and similar clean environments.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a pharmaceutical composition for treating benign prostatic hyperplasia and a preparation method thereof. The composition is prepared from the following medicinal materials in parts by weight: 6 to 8 parts of radix aconiti lateralis preparata, 3 to 5 parts of cortex cinnamomi, 10 to 15 parts of fructus alpiniae oxyphyllae, 10 to 15 parts of fructus psoraleae, 5 to 10 parts of semen myristicae, 5 to 10 parts of ground beeltle, 8 to 12 parts of spina gleditsiae, 10 to 15 parts of radix angelicae sinensis, 8 to 12 parts of radix linderae, 15 to 20 parts of radix rehmanniae praeparata, 10 to 15 parts of fructus corni, 8 to 12 parts of rhizoma anemarrhenae, 15 to 20 parts of radix scrophulariae, 8 to 12 parts of rhizoma alismatis, 5 to 10 parts of radix stephaniae tetrandrae and 10 to 15 parts of radix cyathulae. The invention provides the self-prepared medicine composition for treating the prostatic hyperplasia, the diseases of patients with the prostatic hyperplasia are remarkably improved through the synergistic effect of all the medicines in the composition, and a new traditional Chinese medicine treatment thought is provided for clinical treatment of the BPH disease. According to the traditional Chinese medicine composition, medicine pairs are increased or decreased on the basis of referring to a traditional Chinese medicine classic treatment compound, the unique traditional Chinese medicine composition is finally formed, and all the medicine pairs in the formula cooperate with one another and are indispensable.

The invention discloses a radix astragali, rhizoma polygonati and ligustrum lucidum ait traditional Chinese medicine preparation for treating myelosuppression as well as a preparation method and a detection method thereof. The preparation is prepared from 50-150 parts of radix astragali, 50-150 parts of wine-processed rhizoma polygonati, 25-75 parts of wine-processed ligustrum lucidum ait, 50-150 parts of blanched rhizoma drynariae, 50-150 parts of radix trichosanthis and 25-75 parts of herba epimedii. The optimal extraction process and refining process are screened out based on effective components and pharmacological activity through a large number of tests, and the optimal preparation process of the Shuanghuangliangwhitening oral liquid and other traditional Chinese medicine preparations is obtained through stability investigation and verification. According to the invention, a thin layer chromatography is adopted, the four medicinal materials of astragalus membranaceus, glossy privet fruit, rhizoma drynariae and herba epimedii are respectively subjected to thin layer chromatography research, and methodology research shows that the method is stable and feasible. The invention establishes a content determination method for astragaloside, calycosin-7-glucoside, specnuezhenide and icariin, establishes a quality standard, and has important significance for ensuring the clinical curative effect and safety of astragaloside, calycosin-7-glucoside, specnuezhenide and icariin.

The invention provides a traditional Chinese medicine preparation quality detection method and system based on multi-dimensional data analysis, and belongs to the technical field of traditional Chinese medicine preparation quality detection. The method comprises the following steps: acquiring mass spectrum data and nuclear magnetic resonance data of various active components in a preparation to generate a multi-dimensional chemical characteristic data set; synchronously collecting corresponding data of the medicinal raw materials, and constructing a process and environment association database; constructing a chemical and process coupling analysis model; and monitoring the production process in real time to obtain the dynamic chemical fingerprint spectrum. By constructing a full-component chemical map and associating the full-component chemical map with process and environmental parameters and combining clinical curative effect data to establish a drug effect and component response curved surface model, the limitation that only a few index components are concerned in traditional detection is broken through, so that a detection result can accurately reflect the multi-target and overall regulation characteristics of the traditional Chinese medicine preparation, and the detection accuracy is improved. The problem that the components are qualified but the curative effect is poor due to single detection dimension is avoided, and the relevance between quality detection and the clinical curative effect is remarkably improved.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a kidney-tonifying and liver-nourishing compound preparation and a preparation method thereof. The compound preparation comprises 5-15 parts of roasted herba epimedii, 5-15 parts of fructus cnidii, 50-70 parts of roasted radix astragali and 10-30 parts of pulp of dogwood fruit. The traditional Chinese medicine composition has remarkable curative effects on various diseases and chronic strain caused by deficiency of liver and kidney and deficiency of blood and essence, such as dizziness, blurred vision, fatigue, swelling and pain of waist, back and limbs, dry mouth and eyes, limb ache and weakness, irregular menstruation, incapability of holding weight or hemiplegia and the like, and has a very good application prospect.

The invention discloses a traditional Chinese medicine uric acid reducing preparation quality evaluation method and system based on big data, and relates to the technical field of traditional Chinese medicine preparation analysis. The quality evaluation method comprises the following steps: S1, acquiring chromatographic characteristic data, active ingredient content data and physical and chemical detection data, performing preprocessing, and constructing a preparation quality database; s2, carrying out consistency analysis through batch detection data of characteristic peaks, and dynamically optimizing a peak identification and correction strategy; s3, fusing the batch co-occurrence frequency, the distinction degree index and the inter-batch fluctuation which are subjected to correction processing, and performing characteristic peak screening through weighted operation; s4, performing multi-dimensional fusion quantitative evaluation by integrating a high-priority characteristic peak screening result, the effective component content data and the physical and chemical detection data; and S5, based on the multi-dimensional fusion evaluation result and historical sample data iterative training and abnormal mapping, parameter optimization and dynamic updating are realized. The problems of inter-batch feature drift and insufficient feature recognition precision of the traditional Chinese medicine uric acid reducing preparation in batch detection are solved.

The invention belongs to the field of traditional Chinese medicine preparations, and particularly relates to an easy-to-absorb oral liquid capable of promoting qi-blood tonifying and a preparation process thereof. Comprising the following steps: preparing an absorption promoter; preparing a stable compatilizer; steaming and extracting the traditional Chinese medicinal materials; and preparing the oral liquid. The method comprises the following steps: carrying out enzymolysis on mixed slurry prepared from asparagus flowers and resina liquidamberis by utilizing cellulose-pectin compound enzyme, freeze-drying the prepared resina liquidamberis-asparagus flower enzymatic hydrolysate to obtain an absorption enhancer, and adding the absorption enhancer in the process of preparing the oral liquid, the absorption rate of intestinal tracts to active ingredients of Chinese wolfberry fruits, poria cocos, Chinese dates and longan aril can be increased, and the effect of promoting qi and blood tonifying and easy absorption of the oral liquid on blood and qi tonifying of human bodies is improved.

The invention provides a traditional Chinese medicine preparation for treating chronic prostatitis, and relates to the technical field of traditional Chinese medicine pharmacy. The traditional Chinese medicine preparation is prepared from black nightshade, hypericum perforatum, yam rhizome, rhizoma sparganii, common sage herb, chingma abutilon seed, polyporus umbellatus, uniflower swisscentaury root, corydalis amabilis, aspongopus, glossy privet fruit, fructus broussonetiae, radix ophiopogonis, tuber fleeceflower stem, day lily and liquorice. The traditional Chinese medicine preparation has the effects of clearing heat and promoting diuresis, promoting blood circulation to remove blood stasis, nourishing yin and soothing nerves and tonifying liver and kidney. The traditional Chinese medicine preparation disclosed by the invention has a remarkable treatment effect on CNP rats, and the prostate pathological injury condition and inflammatory response of the CNP rats are effectively relieved. In addition, the traditional Chinese medicine composition has a good treatment effect on relieving pain, frequent micturition, urgent urination, dysuria and other clinical symptoms and inflammation conditions of patients, and has a high total treatment effective rate on chronic prostatitis. The traditional Chinese medicine preparation provides a new scheme for treating chronic prostate.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine essential oil microencapsulation transdermal absorption process. The core of the process is that a transdermal enhancer, traditional Chinese medicine essential oil and a wall material are synchronously added in an emulsification stage, a uniform emulsion system is formed through emulsification treatment, then curing treatment is performed to enable the wall material to be crosslinked to form microcapsules, and the microcapsules are separated, dried and dispersed in a matrix to prepare the transdermal preparation. According to the method, full integration of a transdermal enhancer and a microcapsule structure is realized, transdermal permeation of essential oil components is effectively promoted, meanwhile, the stability and biological activity of the essential oil are kept, and the clinical application value of the traditional Chinese medicine essential oil is improved.

This invention belongs to the field of traditional Chinese medicine preparation analysis, specifically disclosing a one-test-multiple-evaluation method for determining the content of seven components in Jinteng Qingbi granules and its application. Using sinomenine as an internal standard, a one-test-multiple-evaluation method is used to establish relative correction factors between sinomenine and gallic acid, neochlorogenic acid, chlorogenic acid, cryptochlorogenic acid, isochlorogenic acid B, and isochlorogenic acid C in Jinteng Qingbi granules. The contents of gallic acid, neochlorogenic acid, sinomenine, chlorogenic acid, cryptochlorogenic acid, isochlorogenic acid B, and isochlorogenic acid C in Jinteng Qingbi granules are calculated using these correction factors. This invention's method is highly practical, simple to operate, cost-effective, and provides accurate and reliable test results, overcoming the shortcomings of existing methods for quality testing of Jinteng Qingbi granules and providing a new approach for quality control and intrinsic quality evaluation of Jinteng Qingbi granules.

The application provides a method for establishing a fingerprint spectrum of Wenshoujieyu granules and the fingerprint spectrum, and relates to the technical field of traditional Chinese medicine preparation detection. The method for establishing the fingerprint spectrum adopts high performance liquid chromatography to detect the Wenshoujieyu granules, and in the method, the chromatographic conditions are as follows: Agilent 5TC-C 18 (2) (4.6mm*250nm, 5um) is used as a chromatographic column; acetonitrile and 0.1% formic acid aqueous solution are used as mobile phases; the flow rate is 1mL*min ‑1 ; the column temperature is 45 DEG C; the injection amount is 15ul; and the detection wavelength is 300nm. The method for detecting the fingerprint spectrum of the Wenshoujieyu granules established by the application is simple in operation, reliable in result, high in stability and precision, and good in repeatability; the fingerprint spectrum provided by the application can be used to comprehensively and effectively control the quality of the preparation, and ensure the stability, reliability and safety of the preparation.

The invention belongs to the field of pharmaceutical composition preparation, and particularly relates to a traditional Chinese medicine composition for invigorating kidney and strengthening yang and a preparation method thereof, the traditional Chinese medicine composition is composed of the following raw materials by weight: 50 g of epimedium, 50 g of cistanche, 50 g of cordyceps sinensis, 50 g of cynomorium songaricum, and 50 g of eucommia ulmoides. The weight ratio of the herba epimedii to the cistanche to the cordyceps sinensis to the cynomorium songaricum to the eucommia ulmoides is the same and is 1: 1: 1: 1: 1. Therefore, through the raw material combination design that the specific medicinal parts of the raw materials are defined and the weight ratio of the herba epimedii to the herba cistanche to the cordyceps sinensis to the cynomorium songaricum to the eucommia ulmoides is 1: 1, the core effective components of the raw materials are distributed in a balanced proportion, and the effect of synergistically constructing a kidney-tonifying essence-strengthening body-strengthening stable effect system is achieved; therefore, the problems that in the background technology, an existing kidney-tonifying and yang-strengthening traditional Chinese medicine preparation is lack of accuracy in raw material proportioning and fuzzy in medicinal part, so that a preparation effect system is unstable, and the requirements of most people with insufficiency of kidney yang cannot be met are solved.

This invention provides a traditional Chinese medicine composition, preparation method, and application for treating uric acid nephropathy, specifically belonging to the field of traditional Chinese medicine preparation technology. The traditional Chinese medicine composition of this invention comprises the following components in parts by weight: Aconitum carmichaelii 3-7 parts, Cinnamomum cassia 1-7 parts, Morinda officinalis 3-10 parts, Sinapis alba 3-9 parts, Fritillaria thunbergii 5-10 parts, Atractylodes lancea 3-9 parts, Coix lacryma-jobi 10-30 parts, Phellodendron chinense 3-12 parts, Pyrrosia lingua 6-15 parts, Dioscorea hypoglauca 9-15 parts, Smilax glabra 15-60 parts, and Prunus persica 5-10 parts. The traditional Chinese medicine composition of this invention can treat uric acid nephropathy, specifically including uric acid nephropathy of kidney yang deficiency type. It has a mild medicinal property, warms the kidney and invigorates the spleen, clears turbidity and detoxifies, and has no toxic side effects.

This invention relates to a traditional Chinese medicine composition for improving cancer-related fatigue, its preparation method, and its application. Belonging to the field of traditional Chinese medicine technology, it solves the technical problems of the lack of modern traditional Chinese medicine preparations for cancer-related fatigue and the lack of a systematic explanation of the pharmacological mechanism. The solution is: a traditional Chinese medicine composition for improving cancer-related fatigue, its preparation method, and its application, formulated according to the principles of principal, assistant, adjuvant, and guide herbs. The principal herbs are Astragalus membranaceus and Codonopsis pilosula; the assistant herbs are Angelica sinensis and Rehmannia glutinosa; the adjuvant herbs are Poria cocos, Citrus reticulata peel, and Ophiopogon japonicus; and the guide herb is Glycyrrhiza uralensis. By weight fraction, the principal herb is 10-18 parts, the assistant herbs are 8-14 parts, the adjuvant herbs are 8-14 parts, and the guide herb is 1-3 parts. The preparation method of the traditional Chinese medicine composition for improving cancer-related fatigue includes the following steps: 1) water extraction; 2) concentration; 3) spray drying; 4) sieving and mixing; 5) granulation; and 6) drying and packaging. Compared with the prior art, this invention has the advantages of convenient administration, stable efficacy, and a systematic explanation of the pharmacological mechanism.

The invention relates to the technical field of medicines, and provides a traditional Chinese medicine preparation and a preparation method thereof.The traditional Chinese medicine preparation is composed of traditional Chinese medicine spray powder, auxiliary materials and a sweetening agent, the addition amount of the auxiliary materials is 0-60% of the total weight of the traditional Chinese medicine spray powder and the auxiliary materials, and the addition amount of the sweetening agent is 0.35-0.65% of the total weight of the traditional Chinese medicine spray powder and the auxiliary materials. The traditional Chinese medicine solid preparation is prepared by adopting a dry granulation method, and the production efficiency and the product quality are remarkably improved by optimizing and regulating the material selection and proportion and process parameters.

The invention provides a traditional Chinese medicine composition, a traditional Chinese medicine preparation, a preparation method and application, and particularly belongs to the technical field of traditional Chinese medicine. The invention provides a traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by weight: 20-50 parts of parched white peony root, 8-15 parts of pawpaw, 10-20 parts of radix clematidis, 20-40 parts of caulis spatholobi, 5-12 parts of honey-fried licorice root, 10-20 parts of fructus broussonetiae, 10-20 parts of radix cyathulae and 5-12 parts of cassia twig. The traditional Chinese medicine composition has great potential in the aspects of treating kOA and inhibiting osteophyte formation, and can be used for improving kOA cartilage injury. Through in-vitro experiments, network pharmacology and in-vivo experiments, the curative effect of XBD in treating kOA and the effect of XBD in inhibiting osteophyte formation are verified, it is proved that XBD has a regulation effect on cartilage degeneration and osteophyte formation, and an important thought is provided for developing innovative drugs with cartilage protection and abnormal osteophyte formation inhibition functions.

The invention relates to a traditional Chinese medicine preparation for preventing and treating poultry mycoplasma synoviae and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 20-30 parts of dried ginger, 10-20 parts of radix sophorae flavescentis, 20-30 parts of cassia twig, 20-30 parts of acanthopanax, 20-30 parts of eucommia ulmoides, 20-30 parts of salvia miltiorrhiza and 20-30 parts of motherwort. Seven traditional Chinese medicines are compounded and have a synergistic effect, the poultry mycoplasma synoviae can be effectively prevented and treated, the normal growth and production performance of poultry can be maintained, the safety of animal products caused by using antibacterial drugs and antibiotics for treatment can be avoided, and the traditional Chinese medicine composition is suitable for popularization and application of large-scale farms.

The invention discloses construction and application of an HPLC (High Performance Liquid Chromatography) fingerprint spectrum for integrally controlling a multi-component material basis of a traumatic injury bone-growing capsule, and belongs to the technical field of quality control of traditional Chinese medicine preparations. According to the method, high performance liquid chromatography and mass spectrometry are combined, and neochlorogenic acid, protocatechuic aldehyde, cryptochlorogenic acid, vanillic acid, rosmarinic acid, alkannic acid, berberine hydrochloride and salvianolic acid B are taken as reference substances; the fingerprint spectrum is successfully constructed by detecting different batches of traumatic injury bone-growing capsules. The method is simple and easy to implement, high in precision, good in reproducibility, accurate and reliable, at least eight components can be confirmed at a time under the same chromatographic condition, the detection efficiency is greatly improved, and time and cost are saved; quality monitoring can be carried out on a plurality of characteristic components of the traumatic injury bone-growing capsule accurately, rapidly and simultaneously, and a powerful guarantee is provided for controlling the quality and ensuring the clinical curative effect of the traumatic injury bone-growing capsule.

The invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for treating or improving prostate diseases and stomach diseases, a traditional Chinese medicine preparation and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw materials: Chinese lobelia, tripterygium wilfordii, selfheal, dandelion, lophatherum gracile, hydrocotyle verticillata and liquorice. The traditional Chinese medicine composition disclosed by the invention is reasonable in compatibility and synergistic in efficacy, can treat prostate diseases such as chronic prostatitis and benign prostatic hyperplasia and stomach diseases such as chronic gastritis and gastric ulcer at the same time by taking a treatment method of clearing away heat and toxic materials, promoting diuresis and treating stranguria, regulating qi and harmonizing stomach and removing stasis and diminishing swelling, has the advantages of definite curative effect, high safety, low recurrence rate, convenience in taking and the like, and is suitable for clinical popularization.

The invention discloses a traditional Chinese medicine composition for treating arthralgia, a traditional Chinese medicine preparation and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine, and the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 10-20 parts of vine of multiflower knotweed, 5-14 parts of rhizoma anemarrhenae, 10-20 parts of dandelion and 10-20 parts of bunge corydalis herb. The composition has a good treatment effect on rheumatoid arthritis, arthritis, arthralgia, muscular pain and the like caused by damp-heat, and can effectively solve the problem of limitation of existing medicines.

The invention belongs to the field of traditional Chinese medicine biological medicine, and particularly relates to a medicinal and edible traditional Chinese medicine composition and a preparation method, a traditional Chinese medicine preparation and application thereof. The invention provides a medicinal and edible traditional Chinese medicine composition which comprises the following components in parts by weight: ginseng, lily, Chinese yam, angelica sinensis, poria cocos, pericarpium citri reticulatae, ginkgo, radix polygonati officinalis, rhizoma zingiberis and honey-fried licorice root. The preparation method comprises the following steps: mixing the raw materials, adding water for soaking, extracting with water, filtering an extracting solution, concentrating filtrate, and collecting paste to obtain a semi-solid extract or a liquid extract; and further drying the obtained semi-solid extract or liquid extract to obtain the solid extract of the traditional Chinese medicine composition. The traditional Chinese medicine composition provided by the invention adopts an all-medicine-food homologous formula, has no toxic or side effect, is suitable for being taken by various people for a long time, has definite functionality, and is creatively compatible aiming at chronic respiratory system diseases, especially chronic obstructive pulmonary disease in a stable phase complex pathogenesis; the traditional Chinese medicine composition can be applied to health-care products for adjuvant therapy of chronic obstructive pulmonary disease or drugs for treatment of chronic obstructive pulmonary disease.

The invention relates to a spleen-tonifying, appetite-stimulating and digestion-promoting traditional Chinese medicine preparation UPLC detection method and a fingerprint spectrum, and belongs to the technical field of medicine detection. The invention aims to solve the technical problems that the existing quality control method of the spleen-tonifying, appetite-promoting and digestion-promoting pills lacks comprehensive and objective analysis on the spleen-tonifying, appetite-promoting and digestion-promoting pills, and the problems of low precision, poor reproducibility, low efficiency and the like during detection of related components in the prior art are solved. According to the technical scheme, the UPLC detection method is characterized in that a mixed standard substance of gallic acid, 5-hydroxymethylfurfural, chlorogenic acid, sinapine thiocyanate, sinapic acid, hyperoside, 3, 6-dimustard acyl sucrose, hesperidin, naringenin, nobiletin and hesperetin is taken as a contrast, an acetonitrile-0. 1% formic acid aqueous solution is taken as a mobile phase, gradient elution is carried out, and the content of chlorogenic acid in the sample is detected. The qualitative and quantitative detection of the effective components of the spleen-tonifying, appetite-promoting and digestion-promoting pill is realized.

This invention relates to the field of traditional Chinese medicine preparation technology, and discloses a Qingfu Chaijin granule, its preparation method, and its application. The Qingfu Chaijin granule comprises the following traditional Chinese medicine raw materials in parts by weight: Bupleurum chinense 8-12 parts, Cyperus rotundus 8-12 parts, Citrus reticulata peel 8-12 parts, Salvia miltiorrhiza 12-18 parts, Curcuma longa 8-12 parts, Angelica sinensis 8-12 parts, Ligusticum chuanxiong 5-8 parts, Foeniculum vulgare 8-12 parts, Amethyst 25-35 parts, Artemisia argyi 5-8 parts, Cistanche deserticola 8-12 parts, Epimedium brevicornu 8-12 parts, and Rehmannia glutinosa 8-12 parts. The invention also discloses the application of the aforementioned Qingfuchaijin granules in the preparation of drugs for relieving or treating dysmenorrhea caused by qi stagnation and blood stasis. By scientifically optimizing the compatibility ratio of Qingfuchaijin granules and combining it with a reasonable preparation process design, the resulting Qingfuchaijin granules have been significantly improved in terms of stability, user experience, and performance. The use of dry granulation or spray drying-dry granulation combined technology effectively reduces the initial moisture content of the granules, significantly reduces the hygroscopicity of the granules, and improves the storage stability of the product.