1287 results about "Chinese Medicinal Formulation" patented technology

The invention provides an online quality detection method of a nerve-soothing and brain-nourishing liquid based on multispectral fusion, and aims at solving the bottleneck problems of long offline time consumption, weak multi-index detection capability, poor dynamic adaptability and the like in the traditional detection technology, and realizing intelligent quality control of the whole process of the production technology. The device integrates an ultraviolet-visible spectrum module, a near-infrared spectrum module and a fluorescence spectrum module, constructs a multi-scale residual convolutional network to extract near-infrared spectrum characteristics, analyzes a fluorescence excitation-emission matrix through bidirectional LSTM, and cooperates with dynamic baseline correction of an ultraviolet spectrum, so that the icariin content detection precision is improved by 40% compared with that of a traditional HPLC method, the heavy metal residue detection lower limit reaches 0.05 ppm, and the detection accuracy is greatly improved. And an innovative solution is provided for intelligent production of traditional Chinese medicine preparations.

The invention discloses a quality control method of a traditional Chinese medicine preparation based on an IV-catfish orifice-freeing prescription, and relates to the technical field of analysis of traditional Chinese medicine preparations, and the quality control method comprises the following steps: carrying out microscopic identification on traditional Chinese medicine components in the IV-catfish orifice-freeing prescription, and determining a pharmacodynamic material basis. According to the quality control method for the traditional Chinese medicine preparation based on the IVV orifice-freeing prescription, various evaluation means such as a drug effect equivalent evaluation index, a stability test, a quality test and a clinical test are comprehensively applied, the consistency and reliability of the curative effect of the traditional Chinese medicine preparation can be remarkably improved, and the drug effect equivalent evaluation index is analyzed from the two factors of drug effect intensity and action time; the method ensures the equivalence of the medicinal component group and the original traditional Chinese medicine preparation, comprehensively detects the raw material medicines and the preparation, including characters, identification, inspection and content determination items, and ensures that the quality of each batch of samples meets the standard, so that the curative effect of the traditional Chinese medicine preparation is effectively guaranteed, and the efficacy of the traditional Chinese medicine preparation is improved.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine preparation for treating Parkinson's disease and a preparation method thereof. The traditional Chinese medicine preparation for treating Parkinson's disease comprises the following raw materials in parts by weight: 20-30 parts of bischofia polycarpa, 17-25 parts of eucommia ulmoides, 12-16 parts of artemisia sphaerocephala, 10-15 parts of lycopodium clavatum, 8-13 parts of elm leaves, 7-14 parts of pericarpium citri reticulatae, 5-10 parts of semen cuscutae and 2-7 parts of liquorice. In the formula, monarch, minister, assistant and guide are reasonably matched, the curative effect is exact, and the effects of regulating qi and blood, nourishing liver, warming kidney, activating blood and dissipating blood stasis are achieved. The compound can effectively improve core symptoms of Parkinson's disease and delay disease progression, is expected to be further developed into clinical drugs for treatment of Parkinson's disease, and provides an innovative scheme for traditional Chinese medicine treatment of neurodegenerative diseases.

The invention discloses a method for using a traditional Chinese medicine preparation to spray the traditional Chinese medicine preparation on the inner wall surfaces with air permeability, humidity regulation, diatom ooze, large white putty walls, inorganic coatings and other adsorption and porous walls, so that the inner wall surface layer has a traditional Chinese medicine health care function. Comprising the following steps: preparing a slow-release traditional Chinese medicine preparation with a health-care function according to health-care and treatment requirements; drying the microporous material which is smeared on the surface of the inner wall and has an adsorption function; the traditional Chinese medicine preparation is uniformly sprayed on a microporous wall, and after being absorbed, the traditional Chinese medicine preparation can be slowly released into a room within an effective time according to treatment and health care requirements, and functional traditional Chinese medicine gas is released into air so as to achieve the effects of improving immunity, delaying senescence, sterilizing, inhibiting diseases and improving air quality. And through mutual compatibility of the medicines, the effects of purifying indoor air and improving living comfort are achieved.

The invention relates to a pharmaceutical composition, in particular to an oral composition for treating allergic rhinitis, which takes magnolia flower and baical skullcap root as monarch drugs, dahurian angelica root, divaricate saposhnikovia root, szechuan lovage rhizome, milkvetch root and Indian buead as ministerial drugs, liquoric root as a guide and the balance as adjuvant drugs. Comprising the following components: 2-3 parts of biond magnolia flower, 2-3 parts of angelica dahurica, 3-5 parts of fructus forsythiae, 3-5 parts of fried burdock, 2-3 parts of divaricate saposhnikovia root, 3-5 parts of dandelion, 3-5 parts of astragalus membranaceus, 3-5 parts of scutellaria baicalensis, 3-5 parts of poria cocos, 3-5 parts of bighead atractylodes rhizome, 10-15 parts of coix seed, 2-3 parts of ligusticum wallichii, 2-3 parts of radix scrophulariae The traditional Chinese medicine preparation for treating wind-heat invading lung and spleen qi weakness type allergic rhinitis has the effects of dispelling wind, clearing lung, dredging nasal orifices and replenishing qi to invigorate the spleen, the symptoms of patients are relieved, and the living quality of vast child patients is improved.

The invention relates to the technical field of chemical component analysis, in particular to a traditional Chinese medicine fingerprint spectrum detection method of a traditional Chinese medicine preparation. The method comprises the following steps: acquiring high-dimensional spectrogram data of the bovine musk deer resuscitation powder, and performing qualitative characteristic analysis on chemical components of the bovine musk desuscitation powder to obtain a chemical component characteristic matrix of the bovine musk desuscitation powder; acquiring multi-modal production data of the bovine musk deer resuscitation powder, and performing high-dimensional feature fusion on the chemical component feature matrix of the bovine musk desuscitation powder and the multi-modal production data of the bovine musk desuscitation powder to obtain a sample feature embedding vector; constructing a chemical component dynamic network according to the sample feature embedding vector, so as to obtain a cattle musk deer resuscitation powder component collaborative network; generating a global fingerprint spectrogram based on the cattle musk deer resuscitation-inducing powder component collaborative network, and performing potential abnormal point spectrum peak correction to obtain an optimized fingerprint spectrogram; and constructing a feature model according to the optimized fingerprint spectrogram to obtain a quality evaluation model of the bovine musk deer resuscitation powder. The accuracy of quality control of the traditional Chinese medicine preparation can be improved.

The invention relates to the technical field of quality detection of traditional Chinese medicine preparations, in particular to a quality detection method of rhizoma pinelliae, rhizoma atractylodis macrocephalae and rhizoma gastrodiae granules, and the rhizoma pinelliae, rhizoma atractylodis macrocephalae and rhizoma gastrodiae granules established by the invention are proved to be safe and effective through quality inspection. The rhizoma pinelliae, rhizoma atractylodis macrocephalae and rhizoma gastrodiae granules not only keep the effects of eliminating dampness, reducing phlegm, calming the liver and calming endogenous wind in an original prescription, but also overcome the defects that a decoction is temporarily decocted, time-consuming and energy-consuming, is easy to mildew and deteriorate after being placed for a long time and the like, are smaller in dosage and more convenient to take, carry, store and transport, and greatly reduce the labor intensity and shorten the labor time, so that the production cost of the rhizoma pinelliae, rhizoma atractylodis macrocephalae and rhizoma gastrodiae granules is reduced. And the burden of people is greatly relieved, the market vacancy is filled, the economic benefit is considerable, and obvious advantages are achieved.

The invention discloses a traditional Chinese medicine composition, a preparation method of the traditional Chinese medicine composition, a traditional Chinese medicine preparation and application of the traditional Chinese medicine preparation, and relates to the technical field of medicine production. 9 to 12 parts of ginkgo leaf; 9-30 parts of radix astragali; 9 to 15 parts of hypericum perforatum; 6 to 15 parts of jujube; 3-9 parts of red ginseng; 9-15 parts of semen ziziphi spinosae; and 3-6 parts of valerian. All the medicines in the traditional Chinese medicine composition have a synergistic effect, the curative effect is enhanced, and the depressive symptom is improved together.

The invention relates to a traditional Chinese medicine decoction piece prescription decoction parameter intelligent generation method and device, a medium and a computer program, and belongs to the technical field of traditional Chinese medicine preparations, and the traditional Chinese medicine decoction piece prescription decoction parameter intelligent generation method comprises the following steps: (1) obtaining a training data set; the artificial intelligence model is used for generating decoction parameters of a traditional Chinese medicine decoction piece clinical prescription; (3) outputting: the target prescription is conveyed to the trained artificial intelligence model, and the artificial intelligence model outputs decoction parameters corresponding to the target prescription for guiding a patient and a decoction center to carry out decoction operation of the traditional Chinese medicine decoction piece compound; the decoction parameters comprise water adding amount, soaking time, decoction time and decoction times. According to the method, the traditional Chinese medicine decoction piece prescription decoction parameters can be automatically generated, and production and guidance of the traditional Chinese medicine decoction piece decoction parameters in a real sense are achieved.

The invention provides a construction method of a fingerprint spectrum of Xinbao pills. The construction method comprises the following steps: 1) preparing a test solution and a mixed reference solution; and 2) constructing the fingerprint spectrum of the Xinbao pill: respectively taking the test solution and the mixed reference substance solution, and performing high performance liquid chromatography detection to obtain the fingerprint spectrum of the Xinbao pill. The invention belongs to the technical field of traditional Chinese medicine preparation detection, and provides a construction method of a fingerprint spectrum of a Xinbao pill, the method is simple and easy to implement, has the advantages of good precision, stability and repeatability and the like, can realize detection of multiple components of the Xinbao pill, and well reflects the overall quality condition of the Xinbao pill; meanwhile, the established HPLC fingerprint spectrum of the Xinbao pill is rich in detection components, totally 21 common characteristic peaks are determined and cover anti-heart-failure active components in ginseng, pseudo-ginseng, venenum bufonis and flos daturae medicinal materials in the Xinbao pill, reference can be provided for comprehensively controlling the internal quality of the Xinbao pill, and the clinical curative effect of the product is further ensured.

The invention provides a traditional Chinese medicine compound for treating sicca syndrome and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine compounds. The traditional Chinese medicine compound provided by the invention has the effects of eliminating dampness and heat, removing blood stasis and promoting salivation, can safely and effectively treat sicca syndrome by improving functions of exocrine glands and regulating immunity, belongs to a pure traditional Chinese medicine preparation, and has no toxic or side effect. The traditional Chinese medicine compound is proved to be capable of remarkably relieving the sicca syndrome, relieving dry mouth and eye symptoms of a patient, relieving fatigue, regulating and controlling a plurality of signals taking RAGE / TLR4 as a core, inhibiting excessive activation of an HMGB1-RAGE / TLR4-NF-kappa B pro-inflammatory pathway from gene and protein levels, inhibiting generation of pro-inflammatory cytokines, reducing inflammatory response and improving the immunity of the patient. The effect of treating the sicca syndrome is achieved. By acting on STAT3 phosphorylation, Tfh proliferation is inhibited, IL-21 secretion is reduced, humoral immune disorder is relieved, and the sicca syndrome is treated, so that the condition of the sicca syndrome is relieved, and the prognosis of the sicca syndrome is improved.

The invention provides a traditional Chinese medicine granule fluidized bed drying uniformity online monitoring and improving method and device, relates to the field of traditional Chinese medicine preparation production and online quality control, and solves the technical problem of uniformity judgment deviation caused by single-bed data isolated monitoring. The method comprises the following steps: inputting secondary bed outlet particle spectral data into a spectral model to obtain a secondary bed predicted water content M2, and integrating temperature data of each bed, process parameters and the secondary bed predicted water content M2 to construct a database. And an input vector set is generated after preprocessing. And inputting the input vector set into a principal component analysis model, performing PCA dimension reduction on the input vector set, extracting main components, and inputting the main components into a Hotelling T-party monitoring model. And calculating a control limit based on multiple batches of historical qualified data, comparing the T-party statistical magnitude with the control limit to judge a drying uniformity grade, and outputting a corresponding regulation and control strategy according to the drying uniformity grade. The method is used in the production and on-line quality control process of the traditional Chinese medicine preparation.

The invention provides a composition for treating sleep disorder, a preparation and a preparation method thereof. The composition comprises spina date seeds, poria with hostwood, cooked pseudo-ginseng, astragalus membranaceus, codonopsis pilosula and fried hawthorn. The traditional Chinese medicine composition is suitable for the technical field of traditional Chinese medicine preparations and can solve the problem of lack of traditional Chinese medicine compositions for improving sleep disorders caused by blood deficiency in the prior art.

The invention discloses fermentation liquor of a traditional Chinese medicine preparation, a preparation method of the fermentation liquor and application of the fermentation liquor in the aspects of losing weight, lowering lipid and / or relieving liver injury. The traditional Chinese medicine preparation is prepared from the following components in parts by weight: 3 to 6 parts of mulberries, 3 to 6 parts of raspberries, 3 to 6 parts of fructus corni, 12 to 20 parts of fructus lycii, 15 to 25 parts of rhizoma polygonati, 15 to 25 parts of fructus crataegi and 2 to 5 parts of semen cassiae. The traditional Chinese medicine preparation is prepared by extracting, sterilizing, cooling, inoculating a leavening agent and fermenting. The mulberry, the raspberry and the dogwood which are medicinal and edible materials are used for replacing fleece-flower root, the original formula of the lipid-lowering drug is combined, the fermentation liquor prepared after fermentation can effectively retain the obesity adjusting effect of the classic formula of the lipid-lowering drug, meanwhile, the biological activity of the lipid-lowering drug is remarkably improved through the optimized compatibility and the probiotic fermentation technology, and the lipid-lowering drug has a good application prospect. A safe and efficient innovative scheme is provided for functional food to intervene in obesity / overweight.

This invention proposes an online quality detection method for An Shen Bu Nao Liquid based on multispectral fusion. Addressing the bottlenecks of traditional detection techniques, such as long offline processing time, weak multi-index detection capabilities, and poor dynamic adaptability, this method achieves intelligent quality control throughout the entire production process. The device integrates ultraviolet-visible spectroscopy, near-infrared spectroscopy, and fluorescence spectroscopy modules. It constructs a multi-scale residual convolutional network to extract ultraviolet-visible spectral features, uses a two-way LSTM to analyze the fluorescence excitation-emission matrix, and employs dynamic baseline correction of the ultraviolet spectrum. This improves the detection accuracy of icariin content by 40% compared to traditional HPLC methods, and achieves a heavy metal residue detection limit of 0.05 ppm, providing an innovative solution for the intelligent production of traditional Chinese medicine preparations.

The invention provides an efficient microbial fermentation device for traditional Chinese medicine preparation processing, and relates to the technical field of traditional Chinese medicine preparation biological fermentation, the efficient microbial fermentation device comprises a tank body and an inlet, the tank body is provided with a rotating assembly, the rotating assembly comprises a first motor and a sealing sleeve, the inner side of the tank body is provided with a stirring assembly, and the stirring assembly comprises a connecting shaft and a rotating pipe; according to the efficient microbial fermentation device for processing the traditional Chinese medicine preparation, when the first motor is damaged, the second motor drives the connecting shaft and the rotating pipe to rotate on the inner side of the tank body, and the connecting shaft and the rotating pipe are driven to rotate through the second motor; therefore, normal stirring and temperature control work in the tank body is guaranteed, abnormal fermentation of microorganisms caused by the fact that stirring and temperature control cannot be conducted on the tank body in the maintenance period of the first motor is avoided, the processing quality of traditional Chinese medicine is guaranteed, fermentation safety of traditional Chinese medicine in the tank body is guaranteed, and the device is suitable for microbial fermentation processing of traditional Chinese medicine preparations.

The invention belongs to the technical field of medicine taste masking, and particularly relates to a traditional Chinese medicine taste-masking water-in-water Pickering emulsion, a microcapsule, a preparation method and application. A first polymer system aqueous solution in which a water-soluble bitter drug is dispersed and a second polymer system aqueous solution in which a particle stabilizer is dispersed are mixed and emulsified, so that the water-soluble bitter drug is embedded into an inner phase of a water-in-water emulsion, and the traditional Chinese medicine taste-masking water-in-water Pickering emulsion is prepared. The traditional Chinese medicine taste-masked water-in-water Pickering emulsion is dried and granulated, and the traditional Chinese medicine taste-masked microcapsule can be obtained. The traditional Chinese medicine taste-masking water-in-water Pickering emulsion and microcapsule provided by the invention have excellent taste-masking effect and good stability, effectively solve the problem of poor taste-masking effect of traditional Chinese medicine preparations, provide a new method for taste masking of extremely bitter traditional Chinese medicines, and have important significance for development and application of traditional Chinese medicine taste-masking preparations.

The invention discloses a poria cocos and flower multiple healing formula as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine preparations. Comprising poria cocos, honeysuckle, scutellaria baicalensis, gallnut, sanguisorba officinalis, lithospermum erythrorhizon and mirabilite. In the formula, the poria cocos has the effects of tonifying spleen, promoting diuresis, calming heart and tranquilizing mind; the honeysuckle flowers have the effects of clearing away heat and toxic materials and dispelling wind and heat; the radix scutellariae has the effects of clearing heat, drying dampness, purging fire and detoxifying; the gallnuts have the effects of clearing lung, reducing fire, clearing damp and healing sore; the radix sanguisorbae has the effects of cooling blood, stopping bleeding, detoxifying and healing sore; in the treatment process of rosacea, the formula can effectively relieve inflammation and improve skin conditions through the effects of clearing away heat and toxic materials, resisting microorganisms, resisting viruses and the like; the problems that in the prior art, the treatment effect on rosacea is unstable, and side effects are large are solved.

The invention discloses a traditional Chinese medicine preparation for treating multi-system atrophic upright hypotension and a preparation method. The traditional Chinese medicine preparation is prepared from the following raw materials: ginseng, astragalus membranaceus, antler, roasted ephedra, rehmannia, radix ophiopogonis, radix paeoniae alba, rhizoma cimicifugae and pericarpium citri reticulatae viride. The traditional Chinese medicine composition has the effects of tonifying qi, warming yang, nourishing blood and yin and ascending and descending qi function, and emphasizes the effect of ascending and descending qi function in blood pressure regulation by perfecting the etiology and pathogenesis of MSA erect hypotension; the pathogenesis of the MSA erect hypotension is mainly viscera asthenia and qi and blood ascending and descending disorder, so that the treatment effect is achieved by ascending yang and nourishing yin.

The invention belongs to the technical field of traditional Chinese medicine preparations, and relates to fingered citron-albizia flower compatible traditional Chinese medicine oral liquid for soothing nerves, helping sleep and resisting depression and a preparation method thereof. The oral liquid consists of medicinal materials such as fingered citron, albizia flower, fried jujube kernel, polygala tenuifolia, lily, angelica sinensis, ginseng, radix curcumae, platycladi seed, rhizoma acori graminei and poria cocos, and is supplemented with components such as honeysuckle, liquorice, medlar, honey, phaseolus calcaratus, salvia miltiorrhiza and lophatherum gracile. The preparation method comprises the following steps: stir-frying jujube kernels, soaking medicinal materials, performing double-stage water decoction extraction, performing vacuum concentration, blending honey, performing ultrasonic treatment, performing pasteurization, filling and the like. Animal experiment results show that the traditional Chinese medicine composition is superior to a plurality of contrast groups in the aspects of improving sleep latency, prolonging sleep time, reducing depression-like behaviors, improving sweet water preference and the like, and shows good compatibility synergy and behavior regulation potential.

The embodiment of the invention provides a traditional Chinese medicine preparation for improving lung qi and yin deficiency constitution and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following raw materials: 1-3 parts of American ginseng, 2-15 parts of Chinese yam, 1.5-9 parts of codonopsis pilosula, 1-6 parts of dendrobium officinale, 1.5-9 parts of rhizoma polygonati, 0.5-2 parts of schisandra chinensis, 2-6 parts of lily, 1-3 parts of pericarpium citri reticulatae, 1-2 parts of liquorice, 1-5 parts of folium mori, 1-3 parts of donkey-hide gelatin, 1-3 parts of mint, 1-6 parts of angelica sinensis and 2-9 parts of coix seeds. Therefore, the traditional Chinese medicine composition has the functions of tonifying qi and yin, clearing heat and moistening lung, replenishing blood and promoting salivation, and relieving cough and reducing sputum, and can be widely applied to chronic cough, various pneumonia, pulmonary tuberculosis, chronic obstructive pulmonary disease, lung malignant tumor, asthma remission period of asthma, respiratory failure and other syndrome-differentiated lung qi and yin deficiency patients.

The invention discloses a feed containing monosodium glutamate by-products and a production method of the feed, and belongs to the technical field of feeds. The fertilizer is prepared from the following raw materials in parts by weight: 60-100 parts of distillers' grains, 20-40 parts of corn sugar residues, 5-12 parts of monosodium glutamate wastewater, 3-8 parts of microbial zymophyte, 15-40 parts of water, 4-10 parts of a traditional Chinese medicine preparation and 8-16 parts of a carrier, wherein the carrier is modified zeolite composite particles. According to the prepared feed containing the monosodium glutamate by-product, recycling of resources is achieved, the storage stability of the feed is improved, the shelf life of the feed is prolonged, meanwhile, the immune antitoxic ability of animals can be improved, and animal growth can be promoted.

The invention provides a pharmaceutical composition as well as a preparation method and application thereof. The pharmaceutical composition comprises the following raw materials in parts by mass: 2-6 parts of radix paeoniae alba, 1-4 parts of ginseng, 1-4 parts of mint and 0.3-3 parts of liquorice. The pharmaceutical composition provided by the invention adopts the radix paeoniae alba, the ginseng, the mint and the liquorice, the mint and the liquorice are medicinal and edible traditional Chinese medicines, and the radix paeoniae alba and the ginseng can be widely applied in a health food raw material list. The pharmaceutical composition is a pure traditional Chinese medicine preparation, has significant antibacterial and anti-inflammatory effects, can effectively inhibit gingival bleeding, reduce dental plaque, reduce gingival sulcus bleeding index, gingival index and dental plaque index, and significantly reduce probe depth, and has a good curative effect. The composition has a remarkable treatment effect on gingivitis and periodontitis and is free of toxic and side effects.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine spray for treating rhinitis and a preparation method thereof.The traditional Chinese medicine spray is prepared from flos magnoliae liliflorae, fructus xanthii, herba ephedrae, fructus forsythiae, flos lonicerae, radix angelicae, herba asari, menthol, herba centipedae and herba menthae. Refining to obtain a fluid extract; and mixing the fluid extract with a penetration enhancer consisting of aminoketone and menthol, a sodium hyaluronate mucous membrane repairing agent, a pH regulator, an isoosmotic adjusting agent and a preservative to prepare spray liquid medicine, and finally performing sterile filtration and filling. Through efficient extraction and synergism of composite auxiliary materials, the permeability and bioavailability of the medicine are remarkably improved, and the symptoms such as nasal obstruction and running nose can be quickly relieved; meanwhile, the anti-inflammatory function and the function of actively repairing the damaged nasal mucosa are achieved, and the recurrence rate is reduced from the source; the pH and osmotic pressure of the preparation are precisely adjusted, the use is comfortable, and the quality is stable and controllable.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine compound preparation for preventing and treating sepsis based on intestinal treatment and gasification regulation and a preparation method and application of the traditional Chinese medicine compound preparation. The composition is prepared from the following medicinal materials in parts by weight: 3 to 10 parts of rheum officinale, 5 to 10 parts of fructus aurantii, 5 to 10 parts of radix aucklandiae, 10 to 15 parts of fructus gardeniae, 10 to 15 parts of dandelion, 10 to 15 parts of fructus forsythiae, 10 to 15 parts of herba artemisiae scopariae, 10 to 15 parts of rhizoma atractylodis, 10 to 15 parts of poria cocos, 10 to 15 parts of radix paeoniae rubra, 10 to 15 parts of radix salviae miltiorrhizae, 15 to 20 parts of astragalus membranaceus, 10 to 15 parts of rhizoma anemarrhenae, 10 to 15 parts of fructus cannabis, 10 to 15 parts of semen pruni and 3 to 6 parts of raw liquorice. The traditional Chinese medicine compound provided by the invention considers the treatment rules of relaxing bowels, purging heat, promoting qi circulation, removing stagnation, detoxifying, dispersing blood stasis, reinforcing qi, nourishing yin and the like, and also considers the effects of relaxing bowels, regulating qi and supporting healthy qi, various diseases of sepsis patients can be remarkably improved through the synergistic effect of the medicines in the formula, and the traditional Chinese medicine compound especially has an obvious curative effect on gastrointestinal dysfunction. A novel traditional Chinese medicine treatment thought is provided for clinical treatment of sepsis diseases.

The invention discloses a traditional Chinese medicine composition for treating or improving hypoovarian reserve function and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by weight: angelica sinensis, parched white paeony root, parasitic loranthus, dodder, roasted rhizoma atractylodis macrocephalae, ligusticum wallichii, herba lycopi, albizia flower and honey-fried licorice root. And after ovulation, morinda officinalis and glossy privet fruit are added. The formula provided by the invention complies with the natural law of human bodies, and according to the growth of qi and blood, yin and yang, nourishing blood, activating blood and tonifying kidney, yin and yang are tonified without stagnation, and blood stasis is removed without hurting healthy qi; meanwhile, the traditional Chinese medicine is used for strengthening the root of acquired days, quieting the main internal organs, combining dynamic and static, regulating qi-blood yin-yang balance and taking the balance as a period. The invention further provides application of the composition or the traditional Chinese medicine extract or the traditional Chinese medicine preparation in preparation of a medicine for treating or improving ovarian reserve hypofunction.

The invention provides an external traditional Chinese medicine preparation for lymphedema, and relates to the technical field of traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from astragalus membranaceus, cassia twig, poria cocos, akebiaquinata, ligusticum wallichii, salvia miltiorrhiza, radix bupleuri, scutellaria baicalensis, lalang grass rhizome and herba lycopi, and all the medicines are combined to jointly achieve the effects of tonifying qi, activating blood, inducing diuresis, soothing liver-qi stagnation and clearing away heat and toxic materials. The traditional Chinese medicine preparation has obvious edema eliminating and anti-inflammatory effects on lymphedema model mice, and the treatment effect is remarkable. Meanwhile, the traditional Chinese medicine preparation for external treatment of lymphedema in traditional Chinese medicine provided by the invention can remarkably improve clinical symptoms of a patient, relieve pain of the patient, help the patient recover a functional state, reduce the level of inflammatory factors, promote edema absorption of the patient and remarkably relieve the lymphedema condition of an affected limb, and the curative effect is remarkable.

The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for treating hashimoto thyroiditis related depression anxiety disorder and application. The traditional Chinese medicine composition comprises astragalus membranaceus, radix pseudostellariae, bighead atractylodes rhizome, pericarpium citri reticulatae, selfheal, thunberg fritillary bulb, oyster, rhizoma cyperi, angelica sinensis, radix bupleuri and liquorice. The traditional Chinese medicine composition can effectively improve the thyroid lymphocyte infiltration degree and the overall inflammatory response level of AIT mice, effectively reduce the number of depression behaviors of the mice and relieve the depression anxiety state. According to the traditional Chinese medicine composition disclosed by the invention, the effects of all the medicines generate a synergistic effect and can be prepared into a traditional Chinese medicine preparation, so that depression and anxiety disorders related to hashimoto thyroiditis can be effectively treated.

The invention provides a traditional Chinese medicine preparation for treating allergic rhinitis and a preparation method thereof, and relates to the technical field of traditional Chinese medicine pharmacy, the traditional Chinese medicine preparation is prepared from radix asteris, schizonepeta spike, cynanchum paniculatum, perillaseed, spina gleditsiae, cottonrose hibiscus leaf, magnolia flower, semen brassicae, cortex lycii radicis, dendrobe, oroxylum indicum and rhodomyrtus tomentosa; an in-vitro experiment shows that the traditional Chinese medicine preparation can remarkably inhibit the activity of hyaluronidase, also can inhibit the release of beta-HEX in an RBL-2H3 cell degranulation model, reduces the HIS level in a cell supernatant, and effectively improves the morphological abnormality caused by degranulation of RBL-2H3 cells; in-vivo experiments show that the traditional Chinese medicine preparation can significantly reduce behavioral scores of mice suffering from allergic rhinitis, inhibit expression of inflammatory factors TNF-alpha, serum Ig E and OVE-sIg E levels and HA concentration, reduce histopathologic changes caused by allergic rhinitis, effectively repair immune injuries of nasal mucosa of the mice and improve the curative effect of the mice. And a safe and effective new strategy is provided for the treatment of allergic rhinitis.

The invention provides a preparation method and a quality detection method of a nutgall standard decoction. The preparation method comprises the following steps: (1) mixing a nutgall medicinal material with water of which the mass is 8-12 times that of the nutgall medicinal material, and sequentially performing first soaking, first decoction and solid-liquid separation to obtain first filtrate and first medicine residues; (2) mixing the first medicine residue with water which is 6-10 times of the mass of the nutgall medicinal material, performing secondary decoction, and performing solid-liquid separation after secondary decoction to obtain a second filtrate; and (3) combining the first filtrate and the second filtrate to obtain a nutgall filtrate, namely the standard nutgall decoction. The method can solve the problem of lack of a preparation method of a standard gallnut decoction in the prior art, and is suitable for the field of traditional Chinese medicine preparations.