Method for producing cordyceps sinensis powder by virtue of liquid fermentation on mixed bacterial strains

A technology of Cordyceps sinensis fungus powder and liquid fermentation, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, plant/algae/fungus/moss components, etc., can solve the problems of limited efficacy and difficult to approach natural cordyceps sinensis in composition, and achieves good results. economic effect

Active Publication Date: 2013-12-11
青海珠峰冬虫夏草原料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the composition of this product made by simple physical mixing is still difficult to approach natural Cordyceps sinensis, and its efficacy is still limited

Method used

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  • Method for producing cordyceps sinensis powder by virtue of liquid fermentation on mixed bacterial strains

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Take the three strains purchased or isolated, Paecilomyces chinensis, Paecilomyces spp. Bacteria were cultured at room temperature for 8 days, and the composition of the slant medium was calculated by weight volume ratio: broad bean powder 5%, glucose 2%, corn flour 3%, peptone 0.75%, agar 2%, bran 1.5%, magnesium sulfate 1%, Dipotassium hydrogen phosphate 0.2% and water 84.55%.

[0028] Inoculate the cultured Mortierella sinensis on the fermentation medium with an inoculation amount of 5-10%, and carry out the first fermentation at 15°C for 7 days; the composition of the fermentation medium is calculated by weight to volume ratio: glucose 2 %, yeast extract 0.5%, peptone 1%, magnesium sulfate 0.1%, dipotassium hydrogen phosphate 0.8%, water 95.6%.

[0029] Mix the Mortierella chinensis after the first fermentation with the Paecilomyces hematalis and Cephalosporium sinensis that have been cultured, and inoculate them together on the fermentation medium with an inoculum...

Embodiment 2

[0032] Take the three strains purchased or isolated, Paecilomyces chinensis, Paecilomyces spp. Bacteria were cultured at room temperature for 10 days, and the composition of the slant medium was calculated by weight volume ratio: broad bean powder 3%, glucose 4%, corn flour 1%, peptone 0.5%, agar 1%, bran 4%, magnesium sulfate 0.1%, Dipotassium hydrogen phosphate 0.05%, water 86.35%.

[0033] Inoculate the cultured Mortierella sinensis on the fermentation medium with an inoculation amount of 5-10%, and carry out the first fermentation at 18°C ​​for 7 days; the composition of the fermentation medium is calculated by weight to volume ratio: glucose 3 %, yeast extract 4%, peptone 0.5%, magnesium sulfate 1%, dipotassium hydrogen phosphate 1%, water 90.5%.

[0034] Mix the Mortierella chinensis after the first fermentation with the Paecilomyces hematalis and Cephalosporium sinensis that have been cultured, and inoculate them together on the fermentation medium with an inoculum siz...

Embodiment 3

[0037] Take the three strains purchased or isolated, Paecilomyces chinensis, Paecilomyces spp. Bacteria were cultured at room temperature for 9 days, and the composition of the slant medium was calculated by weight volume ratio: broad bean powder 4%, glucose 2.5%, corn flour 4%, peptone 2%, agar 0.5%, bran 1%, magnesium sulfate 0.8%, Dipotassium hydrogen phosphate 1%, water 84.2%.

[0038] Inoculate the cultured Mortierella sinensis on the fermentation medium with an inoculation amount of 5-10%, and carry out the first fermentation at 16°C for 8 days; the composition of the fermentation medium is calculated by weight to volume ratio: broad bean powder 4%, glucose 5%, corn flour 3%, peptone 1%, yeast extract 2%, magnesium sulfate 0.9%, dipotassium hydrogen phosphate 0.2%, water 83.9%.

[0039] Mix the Mortierella chinensis after the first fermentation with the Paecilomyces hematalis and Cephalosporium sinensis that have been cultured, and inoculate them together on the ferment...

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Abstract

The invention relates to a method for producing cordyceps sinensis powder by virtue of liquid fermentation on mixed bacterial strains. The method comprises cultivation of bacterial strains, fermentation, solid-liquid separation, drying and smashing. The method for producing the cordyceps sinensis powder by virtue of the liquid fermentation on the mixed bacterial strain is characterized in that the fermented bacterial strains are hirsutella sinensis, hepialidae paecilomyces varioti and China cephalosporium. According to the method, three different bacterial strains, namely hirsutella sinensis, hepialidae paecilomyces varioti and China cephalosporium, are utilized, respective fermentation and growth characteristics of the three different bacterial strains are combined, the cordyceps sinensis powder which is closer to natural cordyceps sinensis in composition and has more effects is obtained by virtue of the liquid fermentation of the three different bacterial strains, and good economic benefit is brought for manual industrialization of cordyceps sinensis.

Description

technical field [0001] The invention relates to a method for producing cordyceps fungus powder by liquid fermentation, in particular to a method for producing cordyceps fungus powder by liquid fermentation of mixed strains. Background technique [0002] Cordyceps sinensis, also known as Cordyceps sinensis, is a traditional precious Chinese medicine in my country. It has various pharmacological effects such as relieving cough, reducing phlegm, lowering serum cholesterol, regulating and enhancing immunity, and anti-tumor. In recent years, the demand for Cordyceps sinensis has increased dramatically at home and abroad. But because Cordyceps sinensis has its strict parasitism and special growth geographical environment, the output is quite limited, and the medicine source is relatively scarce. In order to alleviate the contradiction between supply and demand in the market, artificial fermentation products of Cordyceps sinensis are becoming more and more important. [0003] At ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/068
Inventor 王玉花王辉杨成香李福奎费文全
Owner 青海珠峰冬虫夏草原料有限公司
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