7 results about "Capsule Dosage Form" patented technology

A transient oil-in-simethicone emulsion for oral administration wherein 5 simethicone is present from 50% to 80% by weight of the emulsion. Also described is the process for the preparation of the transient oil-in-simethicone emulsion and capsule dosage form.

The invention provides a nicotine sustained-release capsule, the nicotine sustained-release capsule comprises a content, the content comprises a sustained-release pellet, the sustained-release pellet comprises an active core, a first coating layer and a second coating layer which are sequentially arranged from inside to outside, the active core comprises at least one of nicotine or a nicotine derivative, the first coating layer comprises a first adhesive, and the second coating layer comprises a second adhesive. The second coating layer comprises a second adhesive, and the second coating layer is an enteric coating; through the design of the nicotine sustained-release capsule dosage form, the drug release rate can be delayed, the stable blood concentration can be maintained, the drug effect duration can be prolonged, the smoking process of'low-dose sustained release 'can be simulated, and the emotion and physiological reaction in the smoking cessation process can be improved; in addition, the design of the double-layer coating is also helpful for stabilizing the fluctuation of the blood concentration, and a safer, more continuous and milder nicotine release process is realized.

This invention relates to the field of traditional Chinese medicine preparations, and discloses a Tongli capsule and its preparation process, comprising the following raw materials: Eupolyphaga sinensis, processed Arisaema heterophyllum, vinegar-processed frankincense, vinegar-processed myrrh, dragon bone, Angelica dahurica, Lysimachia christinae, safflower, Notopterygium incisum, Angelica sinensis, Saposhnikovia divaricata, Cimicifuga foetida, Ligusticum chuanxiong, and Acorus tatarinowii; wherein, the raw materials are dried, pulverized, mixed, and then filled into capsule shells to form capsules. This Tongli capsule, using a total of fourteen traditional Chinese medicines as raw materials, follows the treatment principles of traditional Chinese medicine of dispelling wind and dampness, relaxing muscles and tendons, and promoting blood circulation and removing blood stasis. It has significant efficacy for late-stage fractures and joint dislocations, joint pain, synovitis, and other diseases caused by wind-cold-dampness obstructing the meridians. Furthermore, the capsule dosage form, with its uniform fine powder contents, makes it convenient to take, provides accurate dosage, has high bioavailability, and improves patient compliance. Compared to decoctions, capsules do not require decocting, making them easier to carry and store; compared to pills and powders, capsules can mask unpleasant odors of the medicine, and disintegrate rapidly, resulting in faster onset of action.

The invention relates to a cabazitaxel composition and application of the cabazitaxel composition. Embodiments provide a composition comprising cabazitaxel and at least one lipid and / or cougsterol, and / or a cougsterol derivative, and / or sodium cholesterol sulfate, in the form of a tablet or capsule, and administering the composition to a subject.

A racanisodamine capsule with high dissolution rate and fast disintegration belongs to the technical field of medicine preparation, and through the innovation of narrow distribution micronization of active ingredients, synergistic compatibility of novel auxiliary materials, capsule type adaptation process and the like, the prepared racanisodamine capsule has the dissolution rate of more than or equal to 95% within 30 min and the accelerated test dissolution rate of more than or equal to 92% within 12 months, the auxiliary materials are plant-derived or degradable ingredients, and the process energy consumption is reduced by more than 20%. The invention expands the dosage form applicable population, further improves the drug effect and safety, is energy-saving and environment-friendly, and conforms to the green pharmaceutical trend.

The enteric-coated Huoxiang Zhengqi soft capsule is prepared from rhizoma atractylodis, pericarpium citri reticulatae, cortex magnoliae officinalis (processed with ginger), radix angelicae, poria cocos, pericarpium arecae, a raw rhizoma pinelliae extract, licorice extract, patchouli oil, perilla leaf oil and an enteric-coated soft capsule shell material. According to the preparation method, heating extraction is replaced by wet grinding extraction, volatile oil and extractum are synchronously collected in the evaporation and concentration process through a scraper film evaporator, the heating time for evaporation and concentration of feed liquid through the scraper film evaporator is short, and heat-sensitive components in a prescription can be prevented from being damaged by heat; the enteric soft capsule shell of the enteric Huoxiang Zhengqi soft capsule is a completely sealed capsule shell, can overcome volatilization and loss of volatile oil in existing tablets and pills, can overcome volatilization and loss of volatile oil caused by poor sealing of an assembly gap between an upper shell and a lower shell of a hard-shell capsule, and can overcome the defects that the enteric soft capsule shell material is insoluble in a gastric solution, so that the enteric soft capsule shell material cannot be dissolved in the gastric solution and cannot be dissolved in the gastric solution. The medicine is dissolved and released in an intestinal environment, so that the damage of gastric acid to medicinal components is avoided.

The invention discloses a composite nutritional food composition capable of enhancing an immune function and a preparation process, and belongs to the field of functional foods. The composition comprises two key modified components, namely a curcumin-beta-cyclodextrin inclusion compound and sulfated low-molecular fucoidin, and rhizoma curcumae longae, yeast beta glucan, zinc gluconate, a cordyceps militaris extract, ganoderma lucidum spore powder, polygonatum polysaccharide, an oyster extracting solution, plant lactobacillus and lactobacillus acidophilus are matched. The preparation process comprises the following steps: mixing the solid components except the probiotics; drying and granulating the liquid extracting solution, and mixing with the solid; and adding the probiotic powder and the auxiliary materials at low temperature, and uniformly mixing to finally prepare a capsule dosage form. Through molecular modification and scientific compounding of core active components, the bioavailability of insoluble components and the immunocompetence of natural polysaccharides are remarkably improved, all the components have a synergistic effect, the organism immune function is safely and effectively enhanced from multiple ways and multiple targets, and the product stability is good.