11 results about "Extended Release Capsule" patented technology

Disclosed herein are compositions and methods for the treatment of inflammatory bowel disease. According to some embodiments, the compositions and methods involve the use of a delayed-release capsule formulation containing a mesalamine layer, a hyaluronan layer, and at least one coating layer.

The present invention discloses a drug release capsule comprising a housing, a first chamber located within the housing, a second chamber, a drug storage chamber provided within the first chamber, and piping connecting the drug storage chamber to an outlet on the housing. The piping has a control unit, which closes the drug release passage under the influence of the air pressure in the second chamber, and opens the drug release passage when the air pressure in the second chamber decreases and / or when the air pressure in the drug storage chamber increases. This facilitates the control of drug release from the drug release capsule.

The invention provides a soil improvement material for ecologically restoring difficult site conditions and a preparation method and application thereof.The soil improvement material capable of being used for plant planting comprises a slow-release capsule coating body, the slow-release capsule coating body is composed of three layers of capsules which are coaxially arranged at intervals, an inner cavity of the inner layer capsule is filled with a fiber drying agent, and the inner layer capsule is filled with a fiber drying agent; a composite material capable of exploding after absorbing soil moisture is filled between the inner-layer capsule and the middle-layer capsule, and dry sand grains are filled between the middle-layer capsule and the outer-layer capsule; the preparation method comprises the following steps: rolling a fiber drying sheet into a solid cylinder structure with a set diameter, tightening the solid cylinder structure with plant fibers to obtain a roll-type plant fiber drying agent, then loading the roll-type plant fiber drying agent into an inner-layer capsule, sealing the inner-layer capsule, and then coating the inner-layer capsule with a composite material and dry sand grains. The soil conditioner can be used for soil improvement in an area with a deep soil layer, and the air permeability and the loose state of the soil can be kept for a long time.

A method for designing and manufacturing a long release capsule for extended delivery of a drug to a patient in an ingestible capsule. The method includes determining a drug volume to be delivered and a drug delivery rate. A buoyancy element is selected based on the drug volume. A release port is selected based on the drug delivery rate and the properties of the drug. The design elements are used to produce a capsule design for an ingestible capsule. The design of the capsule is used to generate manufacturing instructions and produce the capsule.

The application relates to the technical field of fresh-keeping materials, in particular to a glucosan-water-soluble cellulose antibacterial material and a preparation method and a fresh-keeping film thereof. The preparation method comprises the following steps: preparing a water-phase solution by using glucosan and water-soluble cellulose, wherein the mass concentration of the glucosan is 1.5-3.5%, and the mass concentration of the water-soluble cellulose is 1.0-2.5%; preparing an oil-phase solution by using an antibacterial agent and an emulsifier; adding the oil-phase solution into the water-phase solution and performing high-speed shearing emulsification to form a nano-emulsion; adding a crosslinking agent into the nano-emulsion to form a crosslinked emulsion with a reticular structure; and preparing the crosslinked emulsion into a slow-release capsule. The preparation method effectively wraps the antibacterial agent by using the mixed system of the glucosan and the water-soluble cellulose, and ensures that the antibacterial agent can be stably released.

The present application belongs to the technical field of environmental protection chemical materials, and particularly relates to a green and environment-friendly high-methyl-etherified resin adhesive and a preparation method thereof. The adhesive comprises a high-methyl-etherified melamine formaldehyde resin matrix and temperature-sensitive slow-release capsules dispersed therein. The capsules are composed of a temperature-sensitive liposome encapsulating a formaldehyde adsorbent and a VOC adsorbent. The preparation method comprises the following steps: synthesizing the resin matrix through a two-step method; preparing the temperature-sensitive liposome by using an ether injection method to encapsulate the adsorbents, and then obtaining capsule powder through freeze-drying; and finally, compounding the two. Through the intelligent response release characteristics of the temperature-sensitive capsules, the present application can accurately release the adsorbents in the curing temperature range of the adhesive, realize in-situ efficient capture of free formaldehyde and volatile organic compounds generated in the curing process, thereby significantly reducing the pollutant emissions in the coating process, and not affecting the original mechanical properties and workability of the adhesive.

The application discloses a kind of hot release repair materials suitable for cold area rush-repair engineering, hot release capsule and preparation method thereof, the hot release repair material suitable for cold area rush-repair engineering of the present application includes the following weight fraction proportion of raw materials: Portland cement 40-70 parts, sulphoaluminate cement 22.5-45 parts, gypsum 7.5-15 parts, hot release capsule 1-5 parts, quartz sand 97-103 parts, water 25.5-26.5 parts, high efficiency water reducing agent 0.25-0.35 parts.The present application incorporates the heat release amount, the heat release rate controllable hot release capsule, forms artificial controllable heat source in the interior of repair material matrix, solves the problem that cement-based repair material is influenced by low temperature under cold climate and strength develops slowly even produces frost injury etc., simultaneously is favorable to reduce cold area rush-repair engineering dependence external heat source, reduce high energy consumption and high carbon emission thus generated.

The application relates to the technical field of exploration and engineering, and provides a karst pipeline slow-release plugging method. The method comprises eight steps: drilling, flexible outer wrapping manufacturing, capsule manufacturing, slurry preparation, plugging device assembly and launching, slurry slow-release solidification, injection mass release and secondary injection. The specific process is as follows: firstly, the karst pipeline is explored; the inflatable flexible outer wrapping is manufactured; the slow-release capsule and the buoyancy capsule are manufactured; the outer slurry and the slow-release slurry are configured according to the size of the flexible outer wrapping and the solidification time; the slow-release slurry is injected into the slow-release capsule, the outer slurry is injected into the flexible outer wrapping, and the slow-release capsule and the flexible outer wrapping are launched into the karst pipeline along the drilling hole; after the solidification time is reached, the injection mass is released by cutting the traction rope and the karst pipeline water flow is detected; if the water flow is greater than a predetermined value, the above operation is repeated; otherwise, secondary injection is carried out along the drilling hole until the water flow is completely plugged. The scheme has the beneficial effect that the karst pipeline high-flow-rate and large-flow-rate underground water can be quickly and effectively plugged.

The application discloses a heat runaway inhibition method and device of an immersed energy storage system. The method comprises the following steps: collecting the splashed immersion liquid drops of heat runaway; forming slow-release capsules with temperature-sensitive migration characteristics based on at least part of the immersion liquid drops; trapping heat runaway reaction gas and establishing driving pressure; using the driving pressure to transport the slow-release capsules to the heat runaway source point; and the slow-release capsules are broken at high temperature to release the immersion liquid drops, thereby inhibiting the heat runaway reaction. The device comprises a cavity, a collection unit, an encapsulation unit, a gas trapping unit and a transportation unit. The application recovers the splashed liquid drops and encapsulates them into temperature-sensitive slow-release capsules, uses the gas pressure of heat runaway to drive transportation, and realizes autonomous targeting by means of the temperature-sensitive migration characteristics of the capsules. On the premise of not relying on external energy and source point prediction, the application realizes closed-loop recycling of the immersion liquid and rapid and accurate inhibition of heat runaway.

A functional food composition for attenuating age-related cognitive decline comprises multiple synergistic and additive nutrient components formulated to mimic Mediterranean and MIND dietary patterns. The composition includes omega-3 fatty acids in phospholipid form from herring roe oil, fat-soluble vitamins including cholecalciferol and tocopherols, carotenoids from marigold extract, B-vitamins including nicotinamide and hydroxocobalamin, magnesium bisglycinate chelate, polyphenolic compounds including catechins, flavonols, anthocyanins, and pterostilbene from various plant sources, and I-theanine. The composition achieves greater than 80% nutrient bioavailability through specialized delivery systems, including immediate-release capsules, delayed-release enteric capsules, and lipophilic softgels. Administration for 4-52 weeks to adults aged 50-90 years with suboptimal dietary patterns produces measurable improvements in biomarkers of cognitive health. A systematic method for developing such compositions based on dietary pattern analysis and multi-criteria nutrient scoring. Additionally, a method of inducing changes in important markers for brain aging and disease using a dietary pattern directed nutritional supplementation regimen.