38 results about "Have Difficulty Swallowing" patented technology

A fast-melting pharmaceutical tablet comprises a porous, plastic substance, a water penetration enhancer and a binder. One or more drugs can be incorporated into the formulation at different stages of the process so as to afford a pharmaceutically active tablet. Methods of making the pharmaceutical tablet entail combining the porous, plastic material, the water penetration enhancing agent, and the binder so as to form highly plastic granules, which are compressed into tablets. The resulting tablets dissolve rapidly in the mouth and have good hardness with low brittleness. The tablets are particularly valuable to those who have difficulty swallowing conventional pills.

The present invention related to a method for oral administration of a solid composition comprising an acid labile proton pump inhibitor compound in the form of a multiple of enteric coating layered pellets, wherein the pellets are in admixture with one or more pharmaceutically acceptable thickeners capable of forming a viscous medium when dispersed in an aqueous carrier. Alternatively, the enteric coated pellets are in admixture with a viscous medium. The formed aqueous viscous suspension is administered through a gastric tube. The method and composition are especially aimed for treatment of patients in need of a proton pump inhibitor and having difficulties to swallow or for pediatric patients.

The present invention is a variably thickened pharmaceutical dosage form, its composition and its use for orally administering medications to patients that have difficulty swallowing other solid dosage forms such as tablets or capsules.

The invention is directed to a pharmaceutical composition of topiramate, an anticonvulsant which is useful for treating epilepsy. More specifically, the present invention provides a solid dosage formulation of topiramate intended primarily for use by pediatric patients, or for patients who have difficulty swallowing tablets. Processes for preparing the pharmaceutical composition are also described.

The compositions of the present invention comprise a therapeutically effective amount of particles consisting of diphenhydramine or pharmaceutically acceptable salts thereof, optionally in combination with another drug such as pseudoephedrine, or phenylephrine and hydrocodone, in combination with rapidly-dispersing microgranules comprising a disintegrant and a sugar alcohol and / or a saccharide. These compositions are useful in treating the symptoms of one or more diseases or conditions in which diphenhydramine (alone or in combination with one or two other drugs) is a therapeutically effective, e.g. allergic rhinitis, sinusitis, upper respiratory tract infections, motion sickness, Parkinson's disease, insomnia, the common cold, and nighttime pain management, particularly for subjects or patients with dysphagia, and people ‘on the move’.

The compositions of the present invention composition comprise a therapeutically effective amount of particles comprising lamotrigine, in combination with granules comprising a disintegrant, and a sugar alcohol and / or a saccharide. These compositions are useful in treating epilepsy and bipolar disorder, particularly for patients with dysphagia, and to improve compliance with bipolar patients.

The invention described herein provides a fast dispersing oral solid dosage form containing monoamine oxidase B inhibitor (MAO-B inhibitor) as the active ingredient, and method of treating disease therewith, such as Parkinson's disease. In one embodiment, the monoamine oxidase B inhibitor selegiline or its analogue can be the sole active ingredient in the composition administered. The dosage form composition is formulated to promote absorption through the buccal, sublingual, pharyngeal and / or esophageal mucous membrane tissue, such that at least 5% of the active ingredient is absorbed within one minute of placement in the oral cavity, as determined by a buccal absorption test. Monoamine oxidase B inhibitor compounds administered in accordance with the invention decrease the amount of undesirable metabolites associated with first pass effect of selegiline, for example, such as amphetamine and methamphetamine. The invention provides a number of other advantages over conventional orally administered tablet forms, including administration of monoamine oxidase B inhibitor compounds to patients that have difficulty swallowing.

The invention discloses an American ginseng effervescent tablet containing vitamin C and a preparation method thereof. The invented product is easy to carry and can be taken by effervescence anytime and anywhere. It retains the ginseng essence of the extract. After effervescence, the fragrance of the original ginseng itself is restored. It provides convenience for people who have difficulty swallowing, without going through the process of gastrointestinal disintegration.

The present invention relates to an oil and fat composition for feeding aids for people with difficulty in swallowing and chewing. Its SFC in the range of 5 to 25°C is 3 to 18%, and it is obtained by emulsifying the oil containing oil and having an HLB value of 1 to 10 The composition obtained by quenching and kneading the composition of the preparation; the food for people with swallowing and chewing difficulties, which contains the above-mentioned oil and fat composition for feeding aids for people with swallowing and chewing difficulties and minced food that can be ingested or Pulverized product; a method for producing a food for people with swallowing and chewing difficulties, wherein the oil and fat composition for feeding aids for people with swallowing and chewing difficulties is mixed with chopped or pulverized foods that can be ingested. The oil and fat composition for feeding aids for difficult persons has an SFC of 3 to 18% in the range of 5 to 25°C, and is obtained by quenching and kneading a composition containing fat and oil and an emulsifier with an HLB value of 1 to 10 of. According to the present invention, it is possible to provide an oil and fat composition for assisting feeding for people who have difficulty swallowing and chewing, and a food for people who have difficulty swallowing and masticating using the oil and fat composition, wherein the oil and fat composition can be easily produced and swallowed, Foods that are easy to ingest for those who have difficulty chewing.

This disclosure provides an extended-release capsule dosage form of metoprolol succinate in the form of coated discrete units, wherein said capsule dosage form is bioequivalent to the marketed Toprol-XL® tablet. The extended-release capsule dosage form comprising coated discrete units can be sprinkled onto food to ease administration to patients who have difficulty swallowing tablets or capsules.

The invention disclosed herein relate to an oral vaccine in which the vaccine composition and adjuvant(s) are carried on a solid fast-dispersing dosage form. The vaccines are targeted toward mucosal tissue and the adjuvant serves to ensure sufficient residence time for the vaccine composition on the mucosal tissue to facilitate its absorption thereby. The fast-dispersing oral solid vaccine dosage form of the invention is particularly useful to administer the vaccine to patients that have difficulty swallowing medications. In one embodiment, the invention provides a fast disintegrating oral solid vaccine dosage form comprising: an immunogenic amount of an antigenic preparation, the antigenic preparation comprising a microsphere-antigen complex; an adjuvant, wherein the adjuvant enhances the absorption of the antigen or potentiates the immunogenic response; a mucoadhesive substance; and a low density dosage form matrix.

The present invention relates to compositions and methods for improving hydration in a subject with dysphagia. More specifically, the present invention provides a method of treating or preventing dehydration in a subject suffering from a swallowing impairment, such as dysphagia, which may comprise administering to a subject suffering from dysphagia an effective amount of a composition comprising a salivating agent and a cooling agent in a weight ratio of 1: 0.06 to 1: 0.2. Optionally, the composition comprises a hemp thorn agent. The composition may be a powder that reconstitutes prior to administration, for example, upon drinking. A thickener or rarefied binder may be included in the powder and / or may be included in a liquid in which the powder is reconstituted. The composition may be a beverage comprising a salivating agent and a cooling agent in a total amount of at least 3.0% by weight of the beverage, for example at least 6.0% by weight of the beverage. The composition may be a ready-to-drink beverage or a frozen confection on a stick.

The invention relates to the fields of medicine and food, in particular to a ginseng freeze-dried orally disintegrating tablet and a preparation method thereof. The present invention solves the rapid disintegration of tablets in the oral cavity through freeze-drying technology in ginseng medicine, food and health food. Good, suitable for people who have difficulty swallowing, such as the elderly and children, to improve medication compliance, and suitable for people with inconvenient drinking water.

A cup for a patient suffering from dysphagia comprises a base upon which the cup is capable of standing when on a level surface and a leading wall extending from the base. The leading wall has a first portion that is substantially planar or concave when viewed from outside the cup, the first portion being at an angle of at least 100 degrees relative to the base. The cup also comprises a trailing wall opposite the leading wall, wherein the trailing wall extends from the base to the lip of the cup; and side walls extending between the leading and trailing walls, the side walls being convex when viewed from outside of the cup. The lip of the cup is upwardly inclined relative to the base in the direction of the trailing wall to the leading wall. The cup allows a patient suffering from dysphagia to drink without having to unduly tip back his or her head.

The invention discloses a swallowing real-time monitoring method and system thereof. The microwave image acquisition unit acquires the microwave image of the throat of the monitored person in a state of eating and drinking in real time as a real-time monitoring image, and the main control unit performs processing according to the real-time monitoring image and reference image data. To determine whether the monitored person has dysphagia. It overcomes the technical problems of poor real-time swallowing monitoring in the existing technology, poor experience of the monitored person, and difficult access to professional inspection equipment or drugs, and realizes real-time and effective monitoring of whether the monitored person has dysphagia, thereby improving the quality of the monitored person. quality of life of the patient.

A thickening powder promotes safe swallowing of a nutritional product by an individual with dysphagia and can be used in methods of treating dysphagia, promoting safe swallowing of a nutritional product, and mitigating a risk of aspiration during swallowing of a nutritional product. The powder contains beta-glucan and at least one carrier ingredient in an amount that is neutral toward or enhances the extensional properties of the nutritional product. The at least one carrier ingredient can be one or more of maltodextrin, isomaltulose, sucrose or lactose. The powder can be diluted in a diluent to form an aqueous solution that is at least a portion of a nutritional product and to improve the cohesiveness of the nutritional product. Preferably, the resultant nutritional product has a shear viscosity greater than 200 mPas and up to about 2,000 mPas, preferably greater than 200 mPas and up to about 500 mPas, more preferably 250 mPas to about 450 mPas, most preferably 250 mPas to about 400 mPas, when measured at a shear rate of 50s-1 at a temperature of 20 DEG C.

This disclosure provides an extended-release capsule dosage form of metoprolol succinate in the form of coated discrete units, wherein said capsule dosage form is bioequivalent to the marketed Toprol-XL® tablet. The extended-release capsule dosage form comprising coated discrete units can be sprinkled onto food to ease administration to patients who have difficulty swallowing tablets or capsules.