Hepatitis virus resistant Chinese medicinal formulation and method for preparing same

A technology for anti-hepatitis virus and traditional Chinese medicine preparations, applied in the directions of antiviral agents, pharmaceutical formulations, medical preparations containing active ingredients, etc., to achieve the effect of low toxicity

Inactive Publication Date: 2006-02-08
北京百世利康医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above drugs play a very important role in the treatment of hepatitis, accounting for more than 60% of the liver disease drug market, but they are all mainly symptomatic treatment, and there are very few anti-hepatitis traditional Chinese medicines that are really antiviral or have better curative effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] The raw materials of the present invention consist of 3000 grams of Phyllanthus urinaria, 1000 grams of Sophora flavescens, 1000 grams of licorice, and 40 grams of total saponins of ginseng stems and leaves.

[0072] (1) Take the prescription amount of Phyllanthus urticae, Sophora flavescens, and licorice, add water and decoct once for 0.8 hours each time, combine the decoction, filter, and concentrate the filtrate into a clear ointment with a relative density of 1.05 at 60°C. The alcohol content is 50%, stir well, let stand overnight, filter the precipitate, the filtrate recovers ethanol and concentrates into a clear ointment with a relative density of 1..05 at 60℃, and then add ethanol to make the alcohol content 70%. Stir thoroughly, let it stand overnight, take the supernatant and concentrate it into a thick paste with a relative density of 1.30 at 60°C, vacuum dry, pulverize into fine powder, and sieve to obtain an extract.

[0073] (2) Preparation of preparations:

[...

Embodiment 2

[0083] The raw material medicine of the invention consists of 4000 grams of Phyllanthus urinaria, 2000 grams of Sophora flavescens, 2000 grams of licorice, and 60 grams of total saponins of ginseng stems and leaves.

[0084] (1) Take the prescription amount of Phyllanthus vulgaris, Sophora flavescens, and licorice, add water and decoct 3 times for 1.5 hours each time, combine the decoction, filter, and concentrate the filtrate into a clear ointment with a relative density of 1.15 at 60°C. Add ethanol to make The alcohol content is 70%, stir well, let stand overnight, filter off the precipitate, the filtrate recovers ethanol and concentrates into a clear paste with a relative density of 1.15 at 60°C, then add ethanol to make the alcohol content 90%, stir well, After standing overnight, the supernatant was concentrated into a thick paste with a relative density of 1.35 at 60°C, dried in vacuum, pulverized into fine powder, and sieved to obtain an extract.

[0085] (2) Preparation of...

Embodiment 3

[0095] The raw materials of the present invention are composed of 3500 grams of Phyllanthus urinaria, 1500 grams of Sophora flavescens, 1500 grams of licorice, and 50 grams of total saponins of ginseng stems and leaves.

[0096] (1) Take the prescription amount of Phyllanthus urticae, Sophora flavescens, and licorice, add water and decoct twice, each time for 1.2 hours, combine the decoction, filter, and concentrate the filtrate into a clear ointment with a relative density of 1.08 at 60°C. Add ethanol to make The alcohol content is 60%, fully stir, let stand overnight, filter the precipitate, the filtrate recovers ethanol and concentrates into a clear cream with a relative density of 1..08 at 60°C, then add ethanol to make the alcohol content 80%, Stir fully and let it stand overnight. Take the supernatant and concentrate it into a thick paste with a relative density of 1.33 at 60°C, dry it in vacuum, pulverize it into fine powder, and sieve to obtain an extract.

[0097] (2) Pre...

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PUM

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Abstract

The invention relates to a hepatitis viruse-resisting Chinese medicinal composition and process for preparation, which is prepared from Chinese herbal extract including blattbulume, flavescent sophora root, licorice root as well as ginseng leaves saponins and medicinal auxiliary materials. The preparation can be made into various oral forms including tablet, capsule, granule, soft capsule, drop pill, oral liquid, slow release tablet and slow release capsule.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and specifically relates to an anti-hepatitis virus Chinese medicine preparation and a preparation method thereof. Background technique [0002] Chronic viral hepatitis is a common clinical disease and frequently-occurring disease. According to reports, the average annual incidence of viral hepatitis in my country is about 120 per 100,000, ranking third among legally reported infectious diseases. There are more than 100 million people who are positive for hepatitis B virus surface antigen (HBsAg) in my country, of which 27.7% are HeAg positive, which is more infectious. There are more than 2.2 million patients with chronic hepatitis in our country, and about 300,000 people die from liver disease every year. Most of the onsets of liver cirrhosis and liver cancer are related to hepatitis B or C virus infection. Due to the complicated transmission route of chronic hepatitis,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/484A61P1/16A61P31/14
Inventor 易小平
Owner 北京百世利康医药科技有限公司
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