17 results about "Phyllanthus urinaria" patented technology

This invention relates to the field of traditional Chinese medicine technology, specifically to a compound traditional Chinese medicine preparation for treating liver cancer, made from the following herbs: cinnamon twig, schisandra fruit, inula flower, immature bitter orange, peony root, scutellaria root, rhubarb, turtle shell, physalis, and wisteria vine. The weight ratio of the above herbs is as follows: cinnamon twig 9g-15g, schisandra fruit 12g-18g, inula flower 9g-15g, immature bitter orange 9g-15g, peony root 12g-30g, scutellaria root 9g-15g, rhubarb 3g-9g, turtle shell 15g-45g, physalis vine 15g-30g, and wisteria vine 15g-30g. This invention can significantly improve symptoms such as hypochondriac pain, poor appetite, depression, abdominal distension, and bitter taste in the mouth, reduce the damage to the digestive system function caused by targeted therapy, improve the quality of life for patients, reduce toxicity and increase efficacy, lower treatment costs, and prolong patient life.

The invention provides a natural plant feed additive for protecting livers and kidneys of livestock and poultry and a preparation method, and relates to the field of feed additives, the feed additive is prepared from centella asiatica, penthorum chinense pursh, felwort, phyllanthus urinaria, purpleflower holly fruit, isatis root, polyporus umbellatus, pericarpium arecae, uncaria, cyrtomium fortunei, talc, cortex acanthopanacis and cassia twig. Experimental data show that the feed additive can significantly inhibit the activities of ALT, AST and ALP in serum, reduce the level of TBIL, enhance the activities of SOD and GSH-Px, recover T-AOC and reduce the generation amount of MDA, so that the multi-dimensional liver protection function of laying hens with acute liver injury is realized; meanwhile, the feed additive can significantly improve the average daily gain of the fattening pigs, reduce the feed-gain ratio, reduce the activity of ALT and AST, increase the content of TP and ALB, and achieve a multi-target comprehensive physiological regulation effect; in addition, the difference between the serum BUN content and the serum Cr content of each group of fattening pigs has no statistical significance, it is proved that the fattening pigs have no risk of renal dysfunction, and a new solution is provided for developing green and efficient functional feed additives.

The invention relates to an automatic preparation method and device of a medicament for treating liver cirrhosis. A traditional Chinese medicine decoction is prepared from the following raw materials in parts by weight: 10 parts of radix astragali, 5 parts of radix notoginseng, 15 parts of radix salviae miltiorrhizae, 10 parts of rhizoma atractylodis macrocephalae stir-fried with bran, 10 parts of poria cocos, 10 parts of fructus aurantii stir-fried with bran, 15 parts of vinegar turtle shell, 5 parts of vinegar schisandra chinensis, 15 parts of vinegar tortoise shell, 10 parts of peach kernel, 10 parts of radix curcumae, 15 parts of Chinese lobelia and 20 parts of phyllanthus urinaria. An automatic preparation device of the liver cirrhosis treatment medicament is applied, and the method comprises the following steps: S1, filling; s2, performing soaking; s3, decocting first; s4, group decoction; s5, later operation is carried out; s6, squeezing; a standardized decoction process aiming at a specific liver cirrhosis treatment prescription can be executed in a single container through exquisite mechanical linkage and automatic control in a whole process without manual intervention, and a specific traditional Chinese medicine formula (astragalus membranaceus, vinegar turtle shell and the like) is deeply combined with an automatic operation process of the device, so that a set of optimized preparation process is formed.

The present invention discloses a traditional Chinese medicine compound preparation for treating chronic liver disease, as well as its preparation method and application. The raw materials of the effective ingredients of the traditional Chinese medicine compound preparation include astragalus, raw oyster, polygonatum, seaweed, poria, salvia miltiorrhiza, zedoaria, raw turtle shell, kelp, phyllanthus urinaria, sophora flavescens, bupleurum, cyperus rotundus, vinegar-cured corydalis, and Panax notoginseng. The traditional Chinese medicine compound preparation of the present invention is mainly used for chronic liver disease and liver fibrosis, and is symptomatic. It has the effects of promoting blood circulation and removing blood stasis, removing dampness and resolving phlegm, softening and dispersing hard masses, and has good absorption effect, significant efficacy, no toxic side effects and clinical adverse reactions. It has a high cure rate for liver fibrosis as clinically verified.

This invention belongs to the field of biomedical technology, specifically relating to the application of phyllanthin (PHY) in the preparation of drugs for the treatment or prevention of colitis. The technical problem this invention aims to solve is to provide a new option for the treatment of colitis. The technical solution of this invention is the application of phyllanthin (PHY) in the preparation of drugs for the treatment or prevention of colitis, ulcerative colitis, or Crohn's disease. This invention is applicable to the treatment or prevention of colitis, providing a treatment solution with both "anti-inflammatory" and "barrier repair" functions.

The invention discloses traditional Chinese medicine granules for treating lung cancer and a preparation method thereof, and relates to the technical field of traditional Chinese medicine formulas. The invention discloses traditional Chinese medicine granules for treating lung cancer. The traditional Chinese medicine composition is prepared from aged black nightshade, marsdenia tenacissima, podophyllum, thunberg fritillary bulb, sculellaria barbata, oldenlandia diffusa, ganoderma applanatum, poria cocos, phellinus igniarius, honeysuckle, fructus forsythiae, dandelion, carbonized sanguisorba root, humifuse euphorbia herb, phyllanthus urinaria, folium isatidis, astragalus membranaceus, cottonrose hibiscus leaves, pericarpium trichosanthis, lance asiabell root, radix ranunculi ternati, spicate clerodendranthus herb, platycodon grandiflorum, aster, rhizoma atractylodis macrocephalae, herba cepbalanoplosis segeti, scorpio, turtle shell, radix ophiopogonis, codonopsis pilosula, radix pseudostellariae, momordica grosvenori, fig, Japanese ardisia herb and pyrrosia lingua. The traditional Chinese medicine has the effects of detoxifying, astringing to stop bleeding, astringing lung and improving symptoms, can finally reduce relapse, and is safe and reliable.

The invention discloses application of a radix astragali-pearl formula in preparation of a medicine for preventing or treating metabolism-related fatty liver diseases, and the radix astragali-pearl formula comprises the following components in parts by weight: 10-20 parts of radix astragali, 10-20 parts of phyllanthus urinaria, 15-30 parts of polygonum cuspidatum, 15-30 parts of rhizoma smilacis glabrae, 10-20 parts of radix paeoniae rubra, 10-20 parts of salvia miltiorrhiza and 15-30 parts of oldenlandia diffusa. The invention provides a water decoction prepared by utilizing the traditional Chinese medicine formula and application of the water decoction in medicines for treating metabolism-related fatty liver diseases. The whole formula has the effects of replenishing qi to invigorate the spleen and removing heat from the liver to dissipate blood stasis as a whole, is used for treating the metabolism-related fatty liver diseases, relieving liver fat deposition, relieving abdominal fat deposition, regulating blood fat metabolism and improving liver functions, and is beneficial to treatment of the metabolism-related fatty liver diseases.

The invention provides a traditional Chinese medicine for relieving itching and diminishing swelling, and relates to the technical field of biological medicine, the traditional Chinese medicine comprises the following components by mass percentage: self-made vinegar accounting for 50%-75% of the total mass of the traditional Chinese medicine, the self-made vinegar is prepared by cooking and saccharifying glutinous rice and polished round-grained rice according to a mass ratio of 1: 1, and fermenting at 6-8 DEG C for 1-2 months; the Chinese herbal medicine semen accounts for 20-45% of the total mass of the traditional Chinese medicines, and the Chinese herbal medicine semen is obtained by mixing a Chinese herbal medicine extracting solution extracted from lysimachia christinae hance and phyllanthus urinaria according to the mass ratio of 1: 1 with honey according to the mass ratio of 4: 1; the skin penetration enhancer accounts for 0.1%-0.3% of the total mass of the traditional Chinese medicine, and the penetration enhancer is a saponin extract; and the acid-base buffer system accounts for 0.1-0.5% of the total mass of the traditional Chinese medicines. The traditional Chinese medicine for relieving itching and diminishing swelling is based on self-made fermented vinegar, Chinese herbal medicine extracts, honey enzymatic hydrolysate and skin permeation enhancing components, a composite, mild and efficient natural external preparation is constructed, and the traditional Chinese medicine can effectively relieve pruritus, inhibit skin inflammation response and promote skin barrier repair.

The invention relates to a traditional Chinese medicine composition for treating gastrointestinal tumor as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine, the traditional Chinese medicine composition for treating gastrointestinal tumor comprises the following components in parts by weight: 30-40 parts of vaccinium bracteatum leaves, 25-35 parts of phyllanthus urinaria, 15-25 parts of astragalus membranaceus, 15-20 parts of poria cocos, 10-18 parts of angelica sinensis, 5-10 parts of pericarpium citri reticulatae, 3-7 parts of rhizoma zingiberis and 2-5 parts of liquorice. The vaccinium bracteatum leaves and the phyllanthus urinaria are used as monarch drugs for clearing away heat and toxic materials and directly attacking tumor poison; radix astragali, Poria cocos and Chinese angelica are used as ministerial drugs, can strengthen immunity and tumor resistance, improve tumor microenvironment and strengthen healthy qi, and assist the monarch drugs to strengthen healthy qi and eliminate pathogenic factors; the dried orange peel and the dried ginger are used as adjuvant drugs to harmonize the spleen and the stomach, and the liquorice is used as a conductant drug to harmonize the medicines, enhance the curative effect, realize multiple effects of resisting tumors, regulating immunity, reducing toxicity and enhancing efficacy, accord with the pathogenesis characteristics of deficiency in vital qi and excess evil of gastrointestinal tumors, and provide a new method for the treatment of gastrointestinal tumors.

The present application belongs to the technical field of natural product development and bioactivity application, and particularly relates to a preparation method of Phyllanthus niruri extract and application thereof in anti-Helicobacter pylori drugs. The Phyllanthus niruri medicinal material is crushed, soaked in purified water, extracted by water bath reflux, concentrated by rotary evaporation, and freeze-dried to obtain the Phyllanthus niruri water extract. The Phyllanthus niruri water extract has obvious anti-Helicobacter pylori activity. The MIC of the Phyllanthus niruri water extract dissolved in brain heart infusion for different strains is as low as 160-320 μg / mL, and the MBC is as low as 320-640 μg / mL. The Phyllanthus niruri water extract is mixed with different antibiotics in different proportions to test the minimum combined inhibitory concentration. It is found that the combined inhibitory index value of the Phyllanthus niruri water extract and clarithromycin for strain ATCC700392 is 0.75, which is an additive effect. Therefore, the Phyllanthus niruri water extract and clarithromycin can be combined to be used in anti-Helicobacter pylori drugs.

A polyherbal formulation for preparing a pharmaceutical composition for the treatment of a liver disease, hepatic injury, or hepatotoxicity in a subject in need thereof, comprising plant material in the form of Rauwolfia serpentina, Eclipta alba, and Phyllanthus amarus.

The present invention discloses herbal cigarette formulation to achieve the complex nicotine stimulation and addresses the symptoms of nicotine rejection with eight categories of herbal ingredients, which includes nerve stimulation herbs (54-80%, preferably 65%), tobacco taste and smell giving herbs (55-80%, preferably 70%), throat clearing herbs (11-35%, preferably 17%), throat burning sensation herbs (3-12%, preferably 4%), fragrance herbs (6-20%, preferably 8%), herbs for fast absorption (4-15%, preferably 5%), herbs for preventing and treating cold and lung diseases (93-98%, preferably 98%), and herbs for preventing and treating cancer (8-20%, preferably 9%). The best formulation is disclosed as; Leucas zeylanica (Plant)- 30%; Desmodium triflorum (Plant)-30%; Vetiveria zizanioides (Root)-2%; Erythroxylum monogynum (Root)-3%; Withania Somnifera (Root)-2%; Glycyrrhiza glabra (Root)-2%; Curcuma longa (Root)-2%; Piper longum L. (Dried immature fruit)-1%; Piper nigrum L. (Dry seeds)-1.5%; Zingiber officinale roscoe (Rhizomes)-1.5%; Bee honey-5%; Justicia Adhatoda (Leaves)-10%; Phyllanthus debilis (Plant)-7%; and Saussurea lappa (Root)-3%.

The application provides a kind of natural plant feed additive for livestock and poultry protection liver and kidney and preparation method, it is related to the field of feed additive, the feed additive is made of gynostemma pentaphyllum, chases yellow grass, gentian, phyllanthus urinaria, winter son, isatis root, polyporus umbellatus, big belly skin, Uncaria, rhinacanthus nasutus, talc, ginseng bark, cassia twig;Experimental data show that the feed additive of the application can significantly inhibit serum ALT, AST, ALP activity, reduce TBIL level, and enhance SOD, GSH-Px activity, restore T-AOC, reduce MDA production to realize the multi-dimensional liver protection function of acute liver injury laying hen;At the same time, the feed additive of the application can significantly improve the average daily gain of fattening pigs, reduce the feed conversion ratio, reduce ALT, AST activity, increase TP, ALB content, and realize the comprehensive physiological regulation effect of multi-target point;In addition, the difference of serum BUN and Cr content of each group of fattening pigs has no statistical significance, which confirms that it has no risk of abnormal kidney function, and provides a new solution for the development of green, efficient functional feed additive.

A multi-herbal formulation for the preparation of a pharmaceutical composition for the treatment of liver disease, liver injury or hepatotoxicity in a subject in need thereof, the multi-herbal formulation comprising plant material in the form of hedyotis diffusa, eclipta alba and phyllanthus bitter.

The invention discloses a plate with antibacterial and insect-repelling functions and a preparation method thereof. The board is a multi-layer composite board prepared by dipping veneers with Chinese herbal medicine extracts with antibacterial and insect-repelling effects and bonding and pressing the veneers. In the bonding and hot pressing processes of the board, no formaldehyde component is released, and the board has the antibacterial and insect-repelling effects. And in the plate steeping liquor, a humifuse euphorbia herb extract and a phyllanthus urinaria extract are combined, and a cortex meliae extract and a radix berberidis extract are combined, so that the antibacterial and parasite expelling effects of the plate are improved, and synergistic interaction is achieved.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for preventing or treating cataract and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines: lespedeza cuneata or senecio scandens, phyllanthus urinaria, chrysanthemum, liquorice, concha haliotidis, asarum and radix angelicae lateralis preparata. The traditional Chinese medicine composition has the effects of clearing heat, reducing internal heat, detoxifying, resisting inflammation, clearing liver, improving eyesight, removing nebula and promoting blood circulation to remove blood stasis, is mainly used for fire excess from yin deficiency, cataract, dark vision and dim vision, and particularly has good prevention and treatment effects on senile cataract. Experimental results show that the traditional Chinese medicine composition has a good treatment effect, is small in taking dosage and convenient to absorb, and can improve the taking compliance of patients, so that the traditional Chinese medicine composition has good development and utilization prospects.

This invention belongs to the field of pharmaceutical formulation technology and provides a topical formulation for herpes lesions and its preparation method. This invention employs a synergistic design of three nanocarriers: a polyvinyl alcohol and sodium alginate composite film-forming matrix, core-shell nanoparticles N1 (chitosan-sodium tripolyphosphate ion-crosslinked core + tannic acid-coated shell), plant polyphenol-phospholipid composite nanoparticles N3 (lecithin composite of Phyllanthus urinaria and Wedelia trifoliata alcohol water extract), and agarwood volatile oil-cyclodextrin inclusion complex N2 (agarwood volatile oil O and hydroxypropyl-β-cyclodextrin inclusion complex). This achieves low viscosity (2-80 mPa·s) and uniform spraying performance that can be atomized by a mechanical pump, dense film coverage and wet-state erosion resistance, and sustained drug release and dispersion stability under high load of multiple nanocarriers. It solves the technical contradiction of existing systems in balancing low viscosity atomization, film density, multi-carrier stability, and low irritation, and has broad application value.