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67 results about "Sophora flavescens" patented technology

Sophora flavescens, the shrubby sophora, is a species of plant in the genus Sophora of the family Fabaceae. This genus contains about 52 species, nineteen varieties, and seven forms that are widely distributed in Asia, Oceania, and the Pacific islands. About fifteen of these species have a long history of use in traditional Chinese medicines. The root is known as Ku shen and is a commonly-used in traditional Chinese medicine.

Traditional Chinese medicine shampoo soap and preparation method thereof

PendingCN122278563AAngelica Sinensis RootGleditsia sinensis
This application relates to the field of shampoo bar technology, and more particularly to a traditional Chinese medicine shampoo bar and its preparation method. The traditional Chinese medicine shampoo bar includes active components of traditional Chinese medicine and basic raw materials for forming the soap body; the active components of traditional Chinese medicine are formed by soaking, decocting, and filtering the following raw materials in the indicated weight ratios: Platycladus orientalis leaves, dried ginger, chrysanthemum, Sapindus mukorossi, Gleditsia sinensis, duckweed, Eclipta prostrata, Ligustrum lucidum, processed Polygonum multiflorum, Sophora flavescens, Kuding tea, peppermint, Artemisia argyi, ginseng, Ganoderma lucidum, Angelica sinensis, mulberry leaves, and Perilla frutescens; wherein, the decoction solvent for the raw materials is rice water. The traditional Chinese medicine shampoo bar formula provided in this application is entirely made from traditional Chinese herbs, has high safety, and has the advantages of effectively cleaning the scalp, preventing hair loss, promoting hair growth, and darkening and brightening hair, effectively solving problems such as oily scalp, itchy scalp, acne on the scalp, increased dandruff, hair loss, and gray hair. The preparation process can maximize the extraction of the effective components of traditional Chinese medicine and can be mass-produced.
Owner:张宁

Traditional Chinese medicine for treating HPV infection in women

The present application relates to a kind of traditional Chinese medicine for treating female HPV infection, which is prepared from the following weight ratio of traditional Chinese medicine raw materials: 2-4 parts of catechu, 2-4 parts of half lotus, 2-4 parts of snakeberry, 1-2 parts of longjin, 1-2 parts of gotu kola, 1-2 parts of wintergreen, 1-2 parts of coptis, and 1-2 parts of sophora. The present application can effectively treat female HPV infection.
Owner:HEBEI COLLEGE OF TRADITIONAL CHINESE MEDICINE

An anorectal disease treating traditional Chinese medicine powder

PendingCN122440737AMyrrhBiology
The application discloses a traditional Chinese medicine powder for treating anorectal diseases and belongs to the technical field of traditional Chinese medicine, and comprises the following components in parts by weight: 20-40 parts of rhubarb, 50-70 parts of mirabilite, 10-30 parts of cape jasmine, 5-15 parts of red peony root, 10-20 parts of dandelion, 15-35 parts of sophora, 5-15 parts of purple flower ground ivy, 5-15 parts of licorice, 10-20 parts of corydalis, 5-15 parts of indigo leaf, 5-15 parts of frankincense, 5-15 parts of sophora flower, 5-15 parts of scutellaria, 5-15 parts of myrrh, 15-25 parts of honeysuckle, 10-20 parts of cortex moutan, 30-50 parts of semen euryae, 5-15 parts of giant knotweed, 15-25 parts of cortex meliae, and 10-20 parts of bletilla. The traditional Chinese medicine powder can prevent anorectal wound infection, reduce postoperative bleeding, reduce anal pain, reduce wound edema, promote wound repair, shorten the healing course and improve the clinical curative effect.
Owner:牟洁霏

Wetness-removing thunder-fire moxibustion stick and preparation method thereof

This invention relates to the field of external moxibustion devices in traditional Chinese medicine, and in particular to a moxa stick for clearing dampness using the thunder-fire method, and its preparation method. The moxa stick comprises moxa wool, compound Chinese herbal powder, and moxa leaf paper; the compound Chinese herbal powder includes principal, assistant, adjuvant, and guiding herbs; the principal herbs include Evodia rutaecarpa, Cinnamomum cassia, and Ligusticum chuanxiong; the assistant herbs include stir-fried Atractylodes lancea, Poria cocos, Polyporus umbellatus, Alisma plantago-aquatica, stir-fried Atractylodes macrocephala, Astragalus membranaceus, and Amomum villosum; the adjuvant herbs include stir-fried Phellodendron chinense, Sophora flavescens, Artemisia capillaris, Gardenia jasminoides, Akebia quinata, Pinellia ternata, Centella asiatica, and Rosa laevigata root; the guiding herbs include Angelica dahurica, Pogostemon cablin, Angelica sinensis, Paeonia lactiflora, Glycyrrhiza uralensis, and Nelumbo nucifera leaf. This invention, guided by compound formulation theory, material innovation, process optimization, and packaging design, provides a thunder-fire moxa stick with strong targeted dampness-clearing properties, stable combustion performance, safety, portability, and controllable quality, showing promising application prospects.
Owner:QIANYUANSEN (BEIJING) BIOTECHNOLOGY CO LTD

Taxus baccata gel

PendingCN122272723ADiseaseLymphatic vessel
The invention patent is titled "Dragon and Cypress Gel," belonging to the pharmaceutical category. The main components of Dragon and Cypress Gel are: Phellodendron bark, earthworm, dragon's blood, Oldenlandia diffusa, Sophora flavescens, and Bletilla striata. In recent years, research on cervicitis and cervical lesions has shown good results using external treatments of traditional Chinese medicine. Vaginal cervical medications are characterized by high local drug concentration, low dosage, and safety and effectiveness, receiving high clinical evaluation. The vagina and cervix have abundant capillaries and lymphatic vessels, and lack clearly defined nerve endings, resulting in minimal pain stimulation for patients during administration. This makes it an effective drug release site for specific diseases such as cervicitis and vaginitis. Traditional Chinese medicine gels are a novel type of external preparation of traditional Chinese medicine. They are made by dissolving or uniformly dispersing traditional Chinese medicine in a gel. These gels adhere tightly to the treatment site for a relatively long time, exhibiting good bioadhesion, and are simple to prepare. It is suitable for use on skin, mucous membranes and cavities. It not only avoids the first-pass effect of enzymes and acids in the gastrointestinal tract that exists in oral administration, but also reduces the adverse reactions of drugs. It has the characteristics of good spreadability, non-greasy feeling, easy to wash off, good transdermal absorption, and comfortable use.
Owner:TAIYUAN YIYUAN ANFANG MEDICAL SERVICES CO LTD

A plant source preservative of gomphocarpus physocarpus and its preparation method and application

This invention discloses a plant-derived preservative for Akebia quinata, its preparation method, and its application, belonging to the field of fruit and vegetable preservation technology. The preservative uses young Akebia quinata fruit as the main raw material, combined with Sophora flavescens, Phellodendron chinense, and Zanthoxylum bungeanum, and is prepared through primary yeast fermentation and secondary fermentation with Lactobacillus plantarum and Bacillus amyloliquefaciens. The preservative significantly reduces polyphenol oxidase (PPO) activity, effectively inhibiting enzymatic browning in Akebia quinata; after 14 days of storage at room temperature, the rot rate decreases to 64%-66%, with effects comparable to imazalil; it delays fruit cracking, reduces the cracking rate, and decreases the length and width of the ventral suture; it also has a significant inhibitory effect on Escherichia coli and Staphylococcus aureus. The product of this invention is purely plant-derived, with no chemical residues, and possesses four functions: inhibiting browning, preventing rot, preventing fruit cracking, and broad-spectrum antibacterial activity. The process is stable, and the application is simple, making it suitable for post-harvest green preservation of Akebia quinata and showing good industrialization prospects.
Owner:THE KEY LAB OF CHEM FOR NATURAL PROD OF GUIZHOU PROVINCE & CHINESE ACADEMY OF SCI

A cream for treating psoriasis vulgaris and a method for preparing the same

This invention discloses a cream for treating psoriasis vulgaris and its preparation method: belonging to the technical field of psoriasis drug technology, this cream is made from the following raw materials in parts by weight: 1-5 parts Tripterygium wilfordii, 1-5 parts Euphorbia fischeriana, 10 parts Catechu, 8 parts Eucalyptus globulus, 10 parts Dictamnus dasycarpus, 10 parts Spatholobus suberectus, 10 parts Sophora flavescens, 10 parts Rehmannia glutinosa, 10 parts Angelica sinensis, 100-140 parts water, 40-50 parts emulsifier, and 0.05-0.1 parts preservative. The preparation method includes: decocting Tripterygium wilfordii, Euphorbia fischeriana, Catechu, Eucalyptus globulus, Dictamnus dasycarpus, Spatholobus suberectus, Sophora flavescens, Rehmannia glutinosa, and Angelica sinensis with water, then removing the herbs to obtain a medicinal paste; mixing the medicinal paste, emulsifier, and preservative and adding them to an emulsifier for emulsification to obtain the product. This formula can treat psoriasis vulgaris. As a topical cream for psoriasis, this invention has antifungal, antiviral, heat-clearing and blood-cooling, and antioxidant activities. It can inhibit epidermal cell proliferation, slow down the epidermal metabolic cycle, promote keratinization, inhibit sebum secretion, inhibit the growth environment of bacteria and fungi, and relieve itching caused by inflammation.
Owner:蔡梓豪

A traditional Chinese medicine compound preparation for treating anal eczema, and a preparation method and application thereof

ActiveCN121015749BWide range of sourcesReduce the area of ​​skin lesionsPerianal pruritusAngelica Sinensis Root
The application belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine compound preparation for treating anal eczema as well as a preparation method and application thereof. The traditional Chinese medicine compound preparation is prepared from the following raw medicinal materials in parts by weight: 35-45 parts of Sophora flavescens, 35-45 parts of Cnidium monnieri, 18-22 parts of Semen Astragali Complanati, 18-22 parts of Cortex Dictamni, 18-22 parts of Scutellaria baicalensis, 118-22 parts of Phellodendri, 10-14 parts of Chuanxiong Rhizoma, 16-20 parts of Angelica sinensis, 10-14 parts of Radix Paeoniae Alba, 16-20 parts of Saposhnikovia divaricata, and 10-14 parts of Gleditsia sinensis. The application provides a traditional Chinese medicine compound preparation and a Chinese medicine treatment method for treating acute and chronic anal eczema caused by 'damp-heat invasion'. The traditional Chinese medicine compound preparation can not only significantly relieve the perianal pruritus and exudation of the patients with anal eczema, but also effectively reduce the skin lesion area and improve the skin lesion state, and the clinical curative effect is obvious. In addition, the raw materials of the traditional Chinese medicine compound preparation are widely sourced and low in price, the pure traditional Chinese medicine raw materials are used for processing, and the preparation process is simple.
Owner:HANZHONG TRADITIONAL CHINESE MEDICINE HOSPITAL

A traditional Chinese medicine exosome complex with anti-HPV and application thereof

The application discloses a traditional Chinese medicine exosome compound with anti-HPV and application thereof, and relates to the technical field of biotechnology.The compound comprises functional components secreted by a human cell co-culture system and a traditional Chinese medicine source extract, and the traditional Chinese medicine source extract is derived from a combined traditional Chinese medicine extract of Astragalus membranaceus, Isatis indigotica Fort., Honeysuckle and Sophora flavescens Ait., and relates to the technical field of biotechnology.The traditional Chinese medicine exosome carries natural active ingredients, and a multi-target anti-virus network is formed by beta-defensin-2 and interferon-gamma generated by co-culture with human cells.Compared with single traditional Chinese medicine extract or chemically synthesized nanoparticles, the HPV inhibition rate is increased by more than 170%, and the direct cytotoxicity of traditional Chinese medicine is reduced through an exosome delivery system, and the IC 50 >200ug / mL, which is significantly lower than that of a water decoction, and mucous membrane irritation experiments show no damage.
Owner:北京圣美细胞生命科学工程研究院有限公司

Special small molecule slow carbon bacterial fertilizer for crab culture and preparation method thereof

The application discloses a kind of small molecule slow carbon bacterial fertilizer special for crab culture and a preparation method thereof, and belongs to the technical field of fertilizer preparation and aquaculture.The small molecule slow carbon bacterial fertilizer raw materials include, by weight: 60-70 parts of non-resistant chicken manure, 30-40 parts of corn bran, 5-10 parts of Sophora flavescens seedling, 0.2-0.4 parts of fermentation bacteria, 0.2-0.4 parts of EM bacteria, 0.3-0.5 parts of chitosan, 0.3-0.5 parts of seaweed extract, 4-6 parts of magnesium chloride hexahydrate, and 2-5 parts of diatomite.The preparation method includes raw material pretreatment, fermentation material mixing, fermentation, aging, crushing and screening, nutrient additive and EM bacteria addition, and packaging and storage.The application balances the carbon-nitrogen ratio, nitrogen-phosphorus ratio, calcium-magnesium ratio and silicon nutrients in water, constructs a "water grass-algae-microorganism" microecological balance system, inhibits green moss and blue algae, kills ciliates, proliferates beneficial bacteria, improves crab immunity, realizes water quality control, substrate improvement, water grass maintenance and growth promotion, and is suitable for crab pond mouth whole-cycle breeding, while realizing agricultural waste resource utilization.
Owner:SHANDONG LELIANG IND CO LTD

An antifungal skin disease agent containing radix paeoniae alba and radix sophorae flavescentis, and a preparation method and application thereof

PendingCN122321034AAntifungalVeterinary Drugs
This invention proposes an antifungal dermatitis agent containing peony bark, white peony root bark, and sophora flavescens, its preparation method, and its application, belonging to the field of veterinary drug technology. It includes an active ingredient and other pharmaceutically acceptable excipients. The active ingredient comprises a traditional Chinese medicine extract and an antifungal compound in a mass ratio of (50-100):1. The traditional Chinese medicine extract is obtained by extracting peony bark, white peony root bark, and sophora flavescens in a mass ratio of (1-3):(2-5):(2-4). The antifungal compound has the structural formula shown in Formula I or a pharmaceutically acceptable salt thereof.
Owner:JINAN GUANGSHENGYUAN BIOTECH

Use of a traditional Chinese medicine composition in the preparation of a medicament for treating intestinal injury

This invention relates to the application of a traditional Chinese medicine composition in the preparation of a drug for treating intestinal injury. The traditional Chinese medicine composition comprises: 50-150 parts of ginseng, 60-180 parts of polygonatum, 40-90 parts of atractylodes, 30-58 parts of sophora flavescens, 60-180 parts of ophiopogon japonicus, 60-110 parts of rehmannia glutinosa, 40-90 parts of polygonum multiflorum, 60-180 parts of cornus officinalis, 40-90 parts of poria cocos, 35-58 parts of eupatorium fortunei, 35-58 parts of coptis chinensis, 35-90 parts of anemarrhena asphodeloides, 35-58 parts of epimedium, 40-110 parts of salvia miltiorrhiza, 60-180 parts of kudzu root, 80-140 parts of litchi seed, and 40-90 parts of lycium chinense root bark. The above-mentioned traditional Chinese medicine composition can inhibit the expression of TNF, AGE-RAGE, TLR and IL-17 and the infiltration of macrophages. It also helps to regulate the proliferation and differentiation of intestinal cells, restore beneficial bacteria in the intestine, and significantly improve the barrier function of the intestine, thereby effectively improving the damaged intestinal function.
Owner:SHIJIAZHUANG YILING PHARMA CO LTD

A sensitive skin suitable targeted acne-removing composition, its preparation method and application

PendingCN122440523APropanoic acidBacillus acnes
The application discloses a targeted acne-removing composition suitable for sensitive skin and a preparation method and application thereof. The targeted acne-removing composition comprises lysozyme, a first extract and a second extract in a mass ratio of 1:(0.1-10):(0.1-5). The first extract comprises guaiacum extract and myrtle fruit extract. The second extract comprises sophora flavescens extract and angelica sinensis extract. The targeted acne-removing composition containing lysozyme, the first extract and the second extract in specific mass ratios can inhibit the activity of propionibacterium acnes, down-regulate the expression of Toll-like receptor 2 (TLR2) and Toll-like receptor 4 (TLR4), and achieve efficient acne removal, and has the mild property and can be suitable for sensitive skin.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

A composition for human papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN) and its preparation method.

PendingCN122075594AAmphibian material medical ingredientsAnthropod material medical ingredientsCnidium monnieriCervical intraepithelial neoplasia
This invention discloses a composition and its preparation method for treating human papillomavirus (HPV) and cervical intraepithelial neoplasia (CIN), belonging to the field of traditional Chinese medicine technology. The formula consists of 6-15 parts of American cockroach, 5-11 parts of hawthorn, 5-11 parts of chicory, 3-9 parts of *Scutellaria baicalensis*, 8-20 parts of *Sophora flavescens*, and 6-15 parts of *Cnidium monnieri*, and also contains 0.01-1 parts by weight of toad venom. The dosage form is one or more of the following: external gel, rinse, foam, suppository, and film preparation. It has high safety and is suitable for HPV infection and CIN changes, solving the problem of poor efficacy in existing treatments.
Owner:ZHONGRUNDA (CHANGZHOU) BIOMEDICAL TECHNOLOGY CO LTD

Composite bactericide containing plant extract and preparation process and application thereof

PendingCN122439699AFluazinamThymelaea
The present application relates to a fungicide for crops, and in particular to a composite fungicide containing plant extracts, a preparation process and application thereof.The composite fungicide comprises plant extracts and a fungicide preparation.The present application selects propineb and fluazinam in a weight ratio of 1:9-9:1 as the fungicide preparation, which can effectively prevent and control grape botrytis cinerea.In addition, plant extracts of chebula, oregano, thyme and sophora flavescens are used to optimize the performance of the extracts in inhibiting grape botrytis cinerea, and the composite fungicide containing plant extracts has good application prospect.
Owner:DAOYUAN SCI & TECH CO GUIZHOU PROV

A granular medicine of erdun-7 and a preparation method thereof

ActiveCN122124183ANervous disorderAnthropod material medical ingredientsRubus sachalinensisElecampane
This invention relates to the field of Mongolian medicine preparation technology, and discloses an Erdun-7 granule preparation and its preparation method, which is made from the following raw materials in parts by weight: 1 part of *Inula japonica* and 1.3-1.8 parts of *Rubus idaeus*, used to regulate qi, relieve exterior symptoms and reduce fever; 1.6-2.4 parts of *Sophora flavescens*, 0.7-1.3 parts of *Gardenia jasminoides*, and 0.7-1.3 parts of *Terminalia chebula*, used to enhance the heat-clearing, fire-purging, detoxifying and blood-cooling effects of *Inula japonica* and *Rubus idaeus*; 0.8-1.2 parts of *Uncaria rhynchophylla* and 0.8-1.2 parts of *Cicada slough*, used to calm the liver, extinguish wind, and stop spasms; and 0.7-1.3 parts of *Kaempferia galanga* and 0.7-1.3 parts of *Melia azedarach*. This Erdun-7 granule preparation and its preparation method target the anticonvulsant effect of the granules, prolonging the latency period and reducing the incidence and severity, which is significantly better than traditional preparations, demonstrating the synergistic effect of clearing heat and relieving exterior symptoms and extinguishing wind and stopping spasms.
Owner:ORDOS MONGOLIAN MEDICINE HOSPITAL (ORDOS MONGOLIAN MEDICINE RES INST)

A clearing acne and acne-removing ointment for treating acne, its preparation method and application

PendingCN122140871AHydroxy compound active ingredientsAerosol deliveryTreatment acneMagnolia officinalis
The present application relates to the technical field of traditional Chinese medicine compositions, in particular to a kind of Qinggua Xiaocuo ointment for treating acne and its preparation method and application.The Qinggua Xiaocuo ointment comprises 400-600 parts of rhubarb, 480-520 parts of sulfur, 150-180 parts of Chinese milk vetch, 380-420 parts of golden cypress, 70-100 parts of white and yellow, 70-90 parts of turmeric, 40-60 parts of Cape jasmine, 20-40 parts of ginger and magnolia officinalis, 20-40 parts of dried tangerine or orange peel, 20-40 parts of Chinese artichoke, 70-100 parts of white peony root, 10-25 parts of borneol, 20-40 parts of prepared rhizoma arisaematis, 150-180 parts of chapter dan, 300-350 parts of sophora, 300-350 parts of scutellaria, and 20-40 parts of licorice.The Qinggua Xiaocuo ointment provided by the present application has the effects of relieving redness, swelling and pain of inflammatory skin lesions, promoting the regression of nodules and pustules, and effectively preventing or treating acne.
Owner:HEILONGJIANG UNIV OF CHINESE MEDICINE

A pharmaceutical composition for treating skin inflammation, and a preparation method and application thereof

PendingCN122440753ADiseaseSenile pruritus
The present application relates to traditional Chinese medicine composition and its application in the field of skin inflammation diseases, and discloses a kind of drug composition for treating skin inflammation and its preparation method and application.The composition is prepared from white fungus, tribulus terrestris, smilax glabra, kochia scoparia, honeysuckle, baishiy, rehmannia glutinosa, oak, peony, radix lithospermi, periostracum cicadae, licorice, gardenia and sophora flavescens.The UPLC-Q-TOF-MS identification contains 110 kinds of components;Animal experiments show that it can significantly reduce psoriasis skin lesions, down-regulate TNF-alpha, IL-1beta and IL-6, up-regulate IL-10, and inhibit PI3K-Akt pathway.The present application has clear components, clear mechanism and definite curative effect, and can be used for preparing medicine for treating psoriasis, chronic urticaria and senile pruritus.
Owner:ZUNYI TRADITIONAL CHINESE MEDICINE HOSPITAL

A traditional Chinese medicine compound for treating insulin resistance of polycystic ovary syndrome

The application provides a traditional Chinese medicine compound for treating polycystic ovary syndrome insulin resistance, and relates to the technical field of traditional Chinese medicine preparation. In the traditional Chinese medicine compound, gentiana scabra, and sophora flavescens are used as monarch drugs, scrophularia ningpoensis, sophora flavescens, smilax glabra, and radix rehmanniae are used as ministerial drugs, and then, humulus scandens, plantago, angelica sinensis, taraxacum, lycopus virginicus, luffa, chihkiu, and curcuma zedoary are used as auxiliary drugs. The whole prescription is used for clearing heat and drying dampness, purging fire and nourishing yin, and promoting dampness and dredging collaterals, and is suitable for treating polycystic ovary syndrome insulin resistance of the liver meridian damp-heat type.
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV

An external synthetic Chinese medicine composition for treating osteomyelitis, sinus and intractable ulcer and a preparation method thereof

The present application relates to the technical field of external use of traditional Chinese medicine, in particular to an external use synthetic traditional Chinese medicine composition for treating osteomyelitis, sinus tract and stubborn ulcer and a preparation method thereof, which comprises, by weight, 10-15 parts of honeysuckle, 10-15 parts of dandelion, 10-12 parts of purple flower ground ivy, 6-10 parts of Chinese cork tree, 6-10 parts of bitter apricot seed, 5-8 parts of red root of sophora, 5-8 parts of Chinese angelica, and 1-4 parts of borneol; the present application is applicable to the infection period and the repair period, realizes the integration of anti-inflammatory, bacteriostasis, muscle regeneration and repair, adopts low-temperature ultrasonic extraction, avoids high-temperature damage to heat-sensitive components, has stronger and more stable efficacy, the formula contains blood-activating and stasis-removing components such as red root of sophora, Chinese angelica, frankincense and myrrh, can promote the penetration of the medicine into deep tissues, has a remarkable effect on the sinus tract and osteomyelitis wound, is a pure traditional Chinese medicine for external use, does not add hormones and antibiotics, is mild in nature, and is suitable for long-term use.
Owner:张红亮

Preparation and application of extract containing gleditsia sinensis l. and antibacterial agent

This invention belongs to the technical fields of biomedicine and daily chemical care industries. It discloses the preparation and application of an antibacterial extract containing Gleditsia sinensis thorns and a formulated combination. Gleditsia sinensis thorns are extracted with 60%–75% ethanol via ultrasonic extraction followed by ethyl acetate extraction, and the extract is purified by column chromatography to obtain a Gleditsia sinensis thorn extract. Eucalyptus leaves and camphor leaves are extracted with supercritical CO2 and purified to obtain essential oils. Sophora flavescens, Gentiana scabra, Lygodium japonicum root, Houttuynia cordata, and Cnidium monnieri are extracted with 70%–85% ethanol via ultrasonic extraction, and the crude extracts are purified using macroporous adsorption resin to obtain extracts. By utilizing the natural antibacterial components of Gleditsia sinensis thorns and its formulated combination, the formulated antibacterial agent not only exhibits high efficiency in inhibiting common bacteria and fungi but also shows good effects against some microorganisms that are difficult to inhibit with traditional chemical antibacterial agents. Compared with traditional chemical antibacterial agents, Gleditsia sinensis thorns and the formulated antibacterial agent, based on natural plant extracts, significantly improve environmental friendliness and safety during use.
Owner:BIJIE MEDICAL COLLEGE (BIJIE HEALTH SCHOOL) +1

Antifungal traditional chinese medicine composition and application

PendingCN122440721ABiotechnologyAntifungal
The application belongs to the field of traditional Chinese medicines, and relates to an antifungal traditional Chinese medicine composition and application. The antifungal traditional Chinese medicine composition is prepared from Sophora flavescens, Coptis chinensis, Phellodendri chinensis, Chinese toon, Cortex Meliae, Cortex Dictamni and Cnidium monnieri. The application provides the antifungal traditional Chinese medicine composition and application which has remarkable bacteriostatic effect, no obvious side effect, can repair skin barrier and is not easy to produce drug resistance.
Owner:XIAN HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Biological pesticide for preventing and treating aphanomyces cochlioides root rot and application thereof

PendingCN122096133ABiocidePlant growth regulatorsBiotechnologySequence analysis
The application discloses a kind of biological source pesticides for preventing and treating aigan's root rot, it includes one or more than two combinations of berberine, ningnanmycin, Sophora flavescens extract, zhongshengmycin, allicin, polyoxin, matrine, osthol, lentinan.The application takes aigan's root and rhizome infected with root rot as research object, obtains a strain of pathogenic bacteria from disease-healthy boundary by separation, purification and pathogenicity determination, and is identified as bean shell ball spores by morphological observation, rDNA-ITS sequence analysis Macrophomina phaseolina Comprehensive indoor and field screening results, the most effective pesticide screened includes 3% zhongshengmycin, 0.5% berberine, 3.5% Sophora flavescens extract and 8% ningnanmycin, and all does not show plant adverse effect and phytotoxicity to aigan growth.Especially, it can significantly reduce malondialdehyde level, while increasing the activity of superoxide dismutase, catalase and peroxidase, so as to improve the disease resistance of aigan.
Owner:NANJING UNIV OF TRADITIONAL CHINESE MEDICINE

A low-irritation bacteriostatic repairing dual-effect external composition for allergic skin problems and a preparation method thereof

PendingCN122297571AUltrasonic emulsificationPhospholipid
This invention discloses a low-irritation, antibacterial, and repairing dual-effect topical composition for allergic skin problems and its preparation method. The composition is a compound of herbal extracts such as Coptis chinensis and Sophora flavescens, and plant essential oils such as clove oil and tea tree oil. An essential oil phospholipid nano-dispersion is prepared by ultrasonic emulsification of phospholipids, followed by cross-linking with a polysaccharide encapsulation material to construct a double-layer microcapsule structure, and finally spray-dried. The composition exhibits pH-responsive release characteristics, with accelerated release of active ingredients under acidic conditions, and maintains stability and antibacterial activity over a wide temperature range of -18℃ to 100℃. This invention effectively solves the problems of poor dispersibility and easy inactivation due to temperature sensitivity of natural active ingredients through a double-layer encapsulation system, achieving broad-spectrum and highly effective antibacterial activity (antibacterial rate > 99.7%), while maintaining a skin irritation index below 0.15. It combines low irritation with highly effective antibacterial and repairing effects, and the preparation process is simple and controllable, making it suitable for sensitive skin care and personal care products.
Owner:HUAIHUA HECHENG DISTRICT KANGSHOUTAI TRADITIONAL CHINESE MEDICINE HOSPITAL CO LTD

A soothing repair composition containing Saint John's wort glycosides and its use in sensitive skin care

PendingCN122140546ACosmetic preparationsAntipyreticChamomile extractInflammation
The present application relates to a soothing repair composition containing Saintgrass nuclease and its application in sensitive skin care, belonging to the technical field of cosmetics. The soothing repair composition containing Saintgrass nuclease includes Saintgrass nuclease, chamomile extract, Sophora flavescens root extract and Magnolia kobus extract, which synergistically act on multiple links such as nerves, immunity and inflammation to comprehensively soothe sensitive symptoms, repair skin barrier, and the effect is significantly better than that of single component, is safe and non-irritating, and has a wide application prospect in the field of skin care.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

A traditional Chinese medicine shampoo for liver and kidney deficiency type androgenetic alopecia, a preparation method and application thereof

PendingCN122351417APaeonia suffruticosaSalvia miltiorrhiza
This invention discloses a traditional Chinese medicine shampoo for androgenetic alopecia caused by liver and kidney deficiency, its preparation method, and its application. Belonging to the field of traditional Chinese medicine technology, the shampoo uses processed Polygonum multiflorum, wine-processed Ligustrum lucidum, Eclipta prostrata, ginseng, Angelica sinensis, safflower, Salvia miltiorrhiza, Platycladus orientalis leaves, mulberry leaves, honey-processed mulberry bark, Sophora flavescens, Cnidium monnieri, Paeonia suffruticosa, Cercis chinensis bark, ginger, Sapindus mukorossi, Gleditsia sinensis, and Clematis chinensis as raw materials, prepared through water extraction and concentration. This invention achieves both symptomatic and root-cause treatment, addressing both the underlying cause and symptoms. It intervenes in androgenetic alopecia through the HIF-1 / VEGE and IL-17 pathways, promoting angiogenesis and improving microcirculation in the scalp, inhibiting follicular immune inflammation, and creating a favorable environment for hair follicle growth. Compared with existing technologies, this invention has irreplaceable advantages in improving local symptoms such as oily scalp, itching, and dandruff.
Owner:YIBIN HOSPITAL OF INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE (YIBIN NANXI DISTRICT TRADITIONAL CHINESE MEDICINE HOSPITAL)

Preparation process of a three-in-one vaginal bacteriostatic solution for bacteriostasis, repair and purification

PendingCN122297603ABiotechnologyCnidium monnieri
This invention discloses a formulation process for a vaginal antibacterial solution that combines antibacterial, repair, and purification functions. It relates to the field of antibacterial wash manufacturing. By weight, its active ingredients consist of 5-15 parts povidone-iodine, 3-8 parts Sophora flavescens root extract, 2-6 parts Cnidium monnieri extract, 1-5 parts yeast extract, 2-8 parts aloe vera extract, 1-4 parts witch hazel extract, and purified water. This invention achieves a synergistic closed-loop effect of antibacterial, detoxifying, and repairing functions through specific component combinations and ratios. Povidone-iodine, combined with Sophora flavescens root extract and Cnidium monnieri extract, achieves dual-targeted antibacterial action; Sophora flavescens root extract and Cnidium monnieri extract, combined with witch hazel extract, achieve active detoxification through physical and chemical adsorption solidification; and aloe vera extract and yeast extract synergistically promote mucosal repair.
Owner:HUNAN HUALIANKANG BIOTECHNOLOGY CO LTD

A plant-based mosquito repellent composition and method of making the same

This invention relates to the field of mosquito repellent composition technology, specifically to a plant-based mosquito repellent composition and its preparation method, comprising Sophora flavescens extract, eucalyptol, montmorillonite glycol, and natural Echinacea purpurea extract; the natural Echinacea purpurea extract is an aqueous extract with a chicoric acid content ≥4%. The plant-based mosquito repellent composition and preparation method of this invention, through functional optimization of single components and synergistic formulation of multiple components, fundamentally solves the core problems of existing plant-based mosquito repellent products, such as poor mosquito repellent effect, short effective duration, and lack of skin soothing function, while also taking into account the product's naturalness and safety. Because a combined low-temperature enzymatic hydrolysis-stepwise alcohol extraction-microfiltration purification process is used to prepare the Sophora flavescens extract, and natural menthol extract is added as a drug guide, the extraction rate and utilization efficiency of plant active ingredients are effectively improved, reducing the waste of plant resources. Furthermore, the preparation process is green and environmentally friendly, generating no harmful waste.
Owner:CHENGDU HUIDE PHARM TECH CO LTD

An antipruritic soothing composition and uses thereof

PendingCN122251300ACosmetic preparationsToilet preparationsPurslane extractSwertia
The application discloses an itching-relieving and soothing composition and application thereof, and the itching-relieving and soothing composition comprises the following components: calamine, an extract of portulaca oleracea, an extract of sophora flavescens, an extract of japaenese swertia, an extract of clematis fruticosa, and the itching-relieving and soothing composition prepared by the application has very good itching-relieving and soothing effects, the calamine has good suspending effect and high safety, and can be widely applied to cosmetics and washing and protecting products.
Owner:RENHE GLOBAL (SHANGHAI) GRAND HEALTH RESEARCH INSTITUTE CO LTD +1