The present application relates to the technical field of
scalp care, and specifically provides a
dandruff-removing composition containing
sophora flavescens polypeptide, a preparation method and application thereof.The
dandruff-removing composition contains various active ingredients such as
sophora flavescens polypeptide SoFla-I,
salicylic acid,
selenium disulfide,
glutathione and
nicotinamide, and is prepared through a specific process.The
amino acid sequence of the
sophora flavescens polypeptide SoFla-I is shown as SEQ ID No.1, and the preparation includes steps such as freeze-
drying of
sophora flavescens roots, ultrasonic extraction,
ammonium sulfate precipitation and
dialysis purification.Experiments show that the composition can effectively inhibit
malassezia, and significantly improve
dandruff and pruritus symptoms, and the dandruff
score and pruritus
score significantly decrease after 14 days of use, and the satisfaction of the subjects is high.The composition of the present application is high in safety and significant in dandruff-removing effect, and is suitable for
shampoo products,
scalp care agents and the like.