33 results about "Nigella" patented technology

The present invention provides a novel nicotine free anticigarette herbal formulation as an anti-dote to the poisoning effects of tobacco products such as Cigarettes, Gutka, Pan masala and other similar tobacco related products. Formulation(s) comprises of sterilized dried plant powder / extracts together with the conventional additives to form the oral dosage forms, which include tablets, capsules, syrup and powders ready for suspension and mouth spray. The anti tobacco addiction herbal formulation comprises of Sesbania grandiflora, Catharanthus roseus, Ocimum sanctum, Myristica fragrans, Elettaria cardamomum, Carum copticum, Syzygium aromaticum, Cinnamomum tamala, Acorus calamus, Zingiber officinale, Piper nigrum, Cinnamomum zeylanicum, Cuminum cyminum, Nigella sativum, Cinnamomum camphora, Piper longum Ocimum gratissimum and Hemidesmus indicus.

The invention discloses an extraction method for Nigella saliniva seed polysaccharide. The method comprises the following concrete steps of: decocting Nigella saliciva seeds with water, carrying out filtering, adding absolute ethyl alcohol into a filtrate until a final concentration is 70 + / -5 V%, carrying out standing, collecting a precipitate, removing protein by a Sevage method after water dissolution of the precipitate, taking a supernatant, adding absolute ethyl alcohol until a final concentration is 70 + / -5 V%, performing standing, washing a precipitate, and freeze-drying the washed precipitate to obtain the Nigella saliniva seed polysaccharide. Experiments show that the Nigella saliniva seed polysaccharide can significantly reduce the levels of FBG, glycated serum protein (GSP), triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), TNF-alpha, IL-6 and IL-1 beta of mice, and can significantly reduce the levels of FBG, glycated serum protein GSP,triglyceride TG, total cholesterol TC, low-density lipoprotein cholesterol LDL-C and increase the expression levels of insulin (INS), high-density lipoprotein cholesterol (HDL-C) and total antioxidantcapacity (T-AOC). The results of intestinal flora composition analysis show that the abundance of the f_Microbacterium_Unclassified bacterial genus and the Bacteroides genus in a model group is obviously reduced, and the Nigella saliniva seed polysaccharide remarkably increases the abundance of the f_Microbacterium_Unclassified bacterial genus and the Bacteroides genus, which indicates that the Nigella saliniva seed polysaccharide can improve the abnormal state of diabetic mice by regulating intestinal microbiota, and is an ideal medicine for treating type 2 diabetes mellitus.

The invention discloses a Xinjiang-Uygur-medicine nigella-sativa shampoo soap and a production technology thereof. The shampoo soap is prepared from nigella sativa seed oil, nigella-sativa plant ash,water, strong base, lavender essential oil and rosemary essential oil. The production technology includes the steps that 1, the nigella sativa seed oil is squeezed, a plant ash solution is prepared, and a base solution is prepared; 2, the plant ash solution and the strong base solution are mixed and added into the nigella sativa seed oil, and stirring and saponification are carried out; 3, the lavender essential oil and the rosemary essential oil are added, the saponified solution is poured into a mold, drying is carried out, and then demolding, cutting and packaging are carried out. The Xinjiang-Uygur-medicine nigella-sativa shampoo soap has the advantages that the shampoo soap has the effects of the three ingredients of the nigella sativa seed oil, the lavender essential oil and the rosemary essential oil, is capable of preventing alopecia, controlling the oil content, removing freckles, whitening the skin, removing wrinkles, tendering the skin and exciting hair regeneration, and isremarkable in hair growth and alopecia preventing effect; the odor is fragrant, hair is smooth and elegant after the shampoo soap is used, and light fragrances of the lavender essential oil and the rosemary essential oil are emitted; the making technology is scientific and simple, the working procedure is simple, and the cost is low.

The present invention relates to a Nigella sativa Method for separating and extracting phenolic glycosides from seeds: drying Nigella sativa After the seeds are crushed, degrease with petroleum ether, extract with 60-80% ethanol, recover the solvent under reduced pressure, and obtain the extract extract; Eluted to obtain 7 components Fr1-Fr7; 3) The fourth component Fr4 was separated by silica gel column chromatography to obtain 5 components 4-1~4-5; 4) Component 4-3 was separated by gel column Chromatography, silica gel column chromatography separation, obtain 3,5 dihydroxyphenethyl alcohol-3- O - β ‑Pyranoside; Component 4‑2 was separated by reverse phase column chromatography and Sephadex LH‑20 dextran gel column chromatography to obtain broadbactin C. The extraction process of the invention is simple, the product is easy to obtain, the solvent can be recycled, the extraction amount is large, and industrial production is possible.

The invention discloses an oleanane-type triterpene saponin and its extraction and separation method and its application. It is confirmed by spectral technology that the oleanane-type triterpene saponin is a new kind isolated from Nigella nigella for the first time. compound. The invention discloses a method for extracting and separating the above-mentioned oleanane-type triterpene saponins from Nigella nigellae. The total saponins are obtained after preliminary extraction and separation by 70% ethanol, and the total saponins are obtained after passing through a silica gel chromatographic column. The crude triterpene saponins were separated and purified by Sephadex LH‑20 gel column and high performance liquid chromatography, and the target compound NGTS was successfully separated. The present invention also discloses for the first time that the above-mentioned oleanane-type triterpene saponins have anti-tumor effects, and in vitro anti-tumor experiments have found that the compounds have obvious inhibitory effects on gastric cancer cells and glioma cells, indicating that they can be further used as new anti-tumor compounds. Drug research and development.

The invention relates to an oral preparation for treating vitiligo, the preparation is prepared by the ana roots, cloves, dried ginger, aniseed, nigella seed, vegetable seedsf, west fruit, acid vine fruit, deworming Vernonia, psoralen, yellow myrobalan skin, belleric terminalia fruit, emblic leafflower fruit, and saffron. The clinical data indicate that 286 cases of patients is inspected and treated, after they takes the preparation 15-20 days, have obvious effect, the white spot area becomes red, continue taking 45 days, 92% of the patients return to normal local pigment, the pigment recoveryarea is more than 85%, after continued three courses of treatment, the disease will not relapse. The preparation is capable of regulating abnormal phlegm, promoting blood-circulation and removing blood stasis, catalyzing the synthesizing of melanin cell, having remarkable effect of treating vitiligo, short curative effect, high curability, is not liable to relapse, no toxic effect deputy to makeup the lack of other drugs.

The invention discloses a Minjiang lily WRKY transcription factor gene LrWRKY2 , whose nucleotide sequence is as described in SEQ ID NO: 1, and encodes a protein with an amino acid sequence as shown in SEQ ID NO: 2, which is confirmed by functional genomics-related technical research in the present invention LrWRKY2 The gene has the function of improving the antifungal effect of the plant, and the antifungal effect of the present invention LrWRKY2 The gene is constructed on a plant expression vector and transferred to tobacco for overexpression. The transgenic tobacco plants have a strong ability to resist fungal infection. The experimental results show that the overexpression LrWRKY2 The transgenic tobacco has a high level of resistance to the infection of Nigeria oryzae, Fusarium solani, Fusarium verticillium, Vitis vinifera, and Alternaria ginseng.

The invention discloses a chitinase gene of Minjiang lily LrCHI2 , the nucleotide sequence of which is described in SEQ ID NO: 1, encoding the protein of the amino acid sequence shown in SEQ ID NO: 2. The present invention is confirmed by technical research related to functional genomics LrCHI2 The gene has the function of improving the plant's resistance to pathogenic fungi. Antifungal gene of the present invention LrCHI2 Constructed on a plant expression vector and transferred to tobacco for overexpression, overexpression LrCHI2 The genetically modified tobacco has a strong ability to resist the infection of Nigersporium oryzae, Streptococcus and Fusarium oxysporum.

The present invention relates to novel black cumin extract compositions and a green process for making the composition. The black cumin extract composition of the invention can be used to treat anxiety, sleep and stress disorders along with significant effect on memory enhancement. The composition is available in oil and powder forms.

The invention discloses a method and a device for extracting nigella plant seed volatile oil and an application of the volatile oil. The method comprises the following steps: extracting, namely extracting volatile oil from soaked ground materials under the microwave irradiation power of 400-700W and the pressure of 0.03-0.05MPa, vaporizing out the volatile oil along with water vapor and feeding into a condensation device; dissolving, namely washing and dissolving the condensed and refluxed volatile oil by an organic solvent; drying to remove water, namely removing water from the organic solvent in which the volatile oil is dissolved through an organic solvent drying water remover; recovering and separating, namely recovering the organic solvent by performing reduced-pressure rotary thin film evaporation on the dried organic solvent in which the volatile oil is dissolved at 28-32 DEG C, wherein the rest liquid is the nigella plant seed volatile oil. According to the method, the volatile oil is extracted by virtue of a microwave-assisted extraction method under the reduced-pressure condition, so that the extraction efficiency is remarkably improved. Meanwhile, the obtained volatile oil is better in aroma quality and suitable for spice and essence research.

The present invention relates to compositions comprising the botanicals from the Family Ranunculaceae, Subclass: Dicotyledonae; Crassinucelli, Superorder: Ranunculales. Examples of these botanicals include but are not limited to; Actaea, Anemone, Ranunculus, and Nigella, or extracts thereof, which are useful in treating liver diseases, particularly those with viral etiology. More specifically, the compositions of the present invention are derived from various botanicals or medicinal plants. The compositions of the invention have demonstrated outstanding efficacy for treatment of patients with hepatic disorders. Compositions of the present invention have also exhibited immunomodulatory activities. The preferred compositions contain the botanical ingredients in concentrations of not less than 20% w / v. The treatment can be therapeutic or prophylactic and may be administered orally, parenterally, as suppository or via nasal mucosa. The treatment may be delivered in a single dose, multi-doses or via a slow release mechanism.

The invention relates to the technical field of application of Nigella tumefica extract, and relates to the application of the extract of Nigella cumin in the preparation of adjuvant arthritis medicine. The present invention discloses for the first time the application of the flavonoids of Nigella tumosa, the volatile oil of Nigella tumosa and the composition of the flavonoids of Nigella tumosa and the volatile oil of Nigella tumosa as the preparation of adjuvant arthritis medicine. Experiments show that the flavonoids of Nigella tumosa, the volatile oil of Nigella tumosa and the composition of the flavonoids of Nigella cumulatus and the volatile oil of Nigella tumosa have a better therapeutic effect on adjuvant arthritis, and have obvious inhibitory effects on adjuvant arthritis. The role of immune function, it is particularly worth mentioning that the composition of Nigella tumefaction flavonoids and volatile oil of Nigella tumefaction has comparable therapeutic effects on adjuvant arthritis and dexamethasone on the disease.

The invention discloses a tipping paper base paper with functions of clearing away heat and relieving alcohol, which is characterized in that it is prepared from the following raw materials in parts by weight: 3-4 parts by weight of ashweed, 1-2 parts of nigella seed oil, and 41 parts by weight of pomegranate pulp -46, cork pulp 52-55, pterygium 2-4, mannitol 1-1.5, Hovenia dulcis 1-2, taurine 0.5-0.7, activated clay 3-4, iron oxide yellow 1-2, Carboresin 2-3, Ammonium Bicarbonate 1-1.6, Calcium Peroxide 2-2.5, Calcium Propionate 1-2, Auxiliary 1-2, appropriate amount of water; the present invention adds Pterocephala clearing heat and detoxifying, Hovenia dulcis Alcohol poisoning, the production of tipping paper base paper has certain health effects, suitable for social use, adding additives, not only can increase the amount of tar adsorption, but also has a natural fragrance, fresh and pleasant, reducing bad breath, and the fiber distribution of the product of the present invention Uniform, small fluctuations in thickness, tightness, air permeability and other indicators, easy to print.

The invention discloses a mascara and a preparation method thereof, belonging to the technical field of cosmetic preparation. The main raw materials of the mascara include: laurocapram, glyceryl monostearate, β-glucan, modified hydroxyethyl cellulose, lecithin, propolis, concentrated watermelon peel juice, actin, beet Alkali, multivitamin, black seed, lovage and mulberry. The raw materials of the invention have mutual synergistic effect, are rich in nutrition, good in absorbability, have good biological activity, can effectively promote the rapid growth of eyelashes, have good antiseptic performance, and are worthy of popularization and application.

The invention discloses a notoginseng sweet protein gene PnTLP2 , its nucleotide sequence is shown in SEQ ID NO: 1, encoding the sweet protein of amino acid sequence shown in SEQ ID NO: 2; PnTLP2 The gene has the function of improving the anti-fungal effect of the plant, and the anti-fungal effect of the present invention PnTLP2 The gene was constructed on a plant expression vector and transferred to tobacco for overexpression. As a result, the transgenic tobacco plants had strong antifungal activity in vitro, and the overexpression PnTLP2 The transgenic tobacco has a significant inhibitory effect on the growth of five plant pathogenic fungi, including Fusarium oxysporum, Fusarium solani, Alternaria ginseng, Sclerotinia and Nigeroryza sativa.

The invention provides an Antrodia fermented product and a preparation method thereof. The preparation method comprises the following steps that (1) Antrodia is soaked in water, extracted, crushed and subjected to mashing, and mash is obtained; (2) after culture medium components are added into the mash, leuconostoc mesenteroides are added to carry out first fermentation, and first fermentation liquor is obtained; (3) pectinase is added into fruit and vegetable liquid with the pH value being 4.5-6 to carry out enzymolysis, and zymolytic fruit and vegetable liquid is obtained; (4) after culture medium components are added into the zymolytic fruit and vegetable liquid, compound lactic acid bacteria are added to carry out second fermentation, and second fermentation liquor is obtained; (5) after culture medium components are added into the second fermentation liquor, compound microzyme is added to carry out third fermentation, and third fermentation liquor is obtained; (6) the first fermentation liquor and the third fermentation liquor are evenly mixed and then centrifuged, and the Antrodia fermented product is obtained after homogenization and sterilization are carried out on centrifuged supernate. The Antrodia fermented product is good in taste and unique in flavor, has good immune adjustment and oxidation resistance functions, and is suitable for the crowd.